... Pro154, Ile156 and Pro161 of the other monomer Similarly, Gly175Ala181 forms an anti-parallel intermolecular b sheet with the b12 of the other monomer, and towards the C-terminus, the subsequent ... in the binding of the phosphate group(s) of FMN or FAD Lys92 forms a salt bridge with the O3P of FMN A salt bridge that involves avin species has not been reported in the structures of the other ... Resolution of the structure of NADP+-bound FeR revealed that the nicotinamide moiety of NADP+ faces the re-side of the isoalloxazine ring, and that the 2Â-P-AMP moiety is held in the groove between the...
Ngày tải lên: 07/03/2014, 02:20
... However, the contextual effects that determine the relevance of the different functions of customer reference marketing are beyond the scope of this study Theoretical implications The results of the ... Frow P (2008) “Managing the co-creation of value”, Journal of the Academy of Marketing Science, Vol 36 No 1, pp, 83-96 Penrose, E T (1959) The Theory of the Growth of the Firm, New York: John ... related to other intangible assets in that they help in building the industrial brand (Blombäck and Axelsson, 2007) and the firm's reputation and credibility (Salminen and Möller, 2006) The existing...
Ngày tải lên: 23/03/2014, 03:20
Báo cáo khoa học: Extraenzymatic functions of the dipeptidyl peptidase IV-related proteins DP8 and DP9 in cell adhesion, migration and apoptosis doc
... molecules [7–9] The functions of DP8 and DP9 are unknown The known characteristics of DPIV and FAP may provide hypotheses concerning DP8 and DP9 function DPIV is predominantly expressed on epithelial ... Despite their close sequence relatedness, DP8 and DP9 exert these differences in their cellular effects Therefore, these two proteins are likely to have different functions and ligands These data ... and dipeptidyl peptidase (DP9)–GFP reduced in vitro wound healing Ratios of the percentage of fluorescent cells in the wound area to the percentage of fluorescent cells in nonwound regions of the...
Ngày tải lên: 23/03/2014, 11:20
Charity Law & Social Policy National and International Perspectives on the Functions of the Law Relating to Charities pptx
... The Advancement of Animal Welfare The Promotion of the Efficiency of the Armed Forces of the Crown, or of the Efficiency of the Police, Fire and Rescue Services ... the profiling of functions and policy in respect of Australia and New Zealand, the United States, Singapore and Canada Part IV, the final section, reflects on the findings of Part III and considers ... to furthering the public benefit of the disadvantaged and in the eyes of society confers upon them a stamp of virtue Free from the exigencies of government, and to some extent also from the competitive...
Ngày tải lên: 29/03/2014, 05:20
bridges the science and art of the worlds most inspiring structures mar 2010
... the thrust to the foot of the cantilever tower, and the two sides of the towers balance each other The downward forces from the towers sit directly on and compress the foundations This idea of ... According to the latest theory the ‘critical number’ of people above which these wobbles will occur depends on the weight of the bridge, its natural frequency, and the amount of damping (i.e the degree ... lengths of rope and pieces of steel or other materials used in a real bridge to find out how strong they are The internal force is acting all along the length of the rope from one of the teams to the...
Ngày tải lên: 11/06/2014, 01:43
báo cáo hóa học:" Multiple functions of the von Willebrand Factor A domain in matrilins: secretion, assembly, and proteolysis" ppt
... matn-1 To further test this hypothesis, we determined whether the presence of the inhibitors of matrix proteases affected the proteolytic processing of matn-1 The presence of mM EDTA in the medium ... I192N, T120M, and E134K [13] Interestingly, all of these MED-causing mutations are located in the β strands in the center of the vWF A domain, which are important for the folding of the protein ... shown that the number of the EGF repeats does not affect the assembly of matrilins [4] In this study, we investigate whether the presence or absence of the vWF A domain adjacent to the coiled-coil...
Ngày tải lên: 20/06/2014, 01:20
prevalence and influencing factors of the lower reproductive tract infections among sex workers in the centre for treatment - education- labour ii hanoi and evaluation of the intervention
... detection testing and treatment regimens at the center, the other activities as providing support materials "International Standard of reproductive health "of the Ministry of Health and other specialized ... staffs of the center Practical meaning: The results of the thesis has performed the effectiveness of the intervention model to help planners and policy makers as well as presventing LRT for FSW and ... improve knowledge and pratising STD managing for health workers, base on that to expand this intervention model for other centers over the nation The layout of the thesis The thesis is presented...
Ngày tải lên: 25/07/2014, 13:32
a study on the forms and meanings of lexical verb get and vietnamese equivalents nghiên cứu hình thái và ngữ nghĩa của động từ get và những tương đương trong tiếng việt
... put it: „Many English verbs have five forms: the base, the –s form, the past, the –ing participle and the –ed participle.‟ Example of these forms are given in the table below: Symbol Regular verbs ... Kim Than, the above Vietnamese sentences use the pattern N1 + V + N2 + N3 in which N1 is the first noun, N2 is the second noun and N3 is the third noun of the sentence and V is the verb of sentence ... INTRODUCTION Rationale of the study Aims of the study Research questions Scope of the study Methodology of the study Design of the study ...
Ngày tải lên: 02/03/2015, 14:22
Study on failure of surface and interface of the laminated composite structures of a small ship
... Doctor of Philosophy Study on the failure of surface and interface of the laminated composite structures of a small ship The Graduate School of the University of Ulsan Department of Mechanical ... and thesis layout The amount and role of surface in composite boat is quite great The interface decides the strength of structures and outer surface impacts on the working efficiency and aesthetics ... performed similarly All these layers will cure together (Fig 2-1) However, the quality of type of joint depends on the properties of resin and fiber and the mixed rate of them So this bonding is...
Ngày tải lên: 12/03/2015, 15:31
TÀI LIỆU HƯỚNG DẪN- the minimum necessary operations and functions for the optimum adjustment of machines
... finalize the setting Then, switch the screens using the and keys When the setting of the items marked with " " is not changed, switch the screens using the and keys without pressing the [Enter] ... detector and the zero tension detection output of the LE-40MTA-E together , and set the speed limit input of the motor to when the material is cut Wiring check • Erroneous connection of the power ... setting of these items,refer to the initial setting Seting screen Standard of volume set output The control output by the manual torque and the stall setting are set by the following standard...
Ngày tải lên: 02/06/2015, 17:54
Molecular and cellular functions of the alternatively spliced isoforms of GDNF receptor complex in neuronal differentiation
... coinfected with mouse RET9 and GFRα2 isoforms The expression levels of RET9 and GFRα2 isoforms were quantified by real-time PCR and normalized to the expression levels of GAPDH The results were expressed ... involved in NTN and NGF induced neurite outgrowth Collectively, these findings demonstrated the hitherto unrecognized role of specific ligands and receptor isoforms in activating STAT3 and the transcription ... the diverse functions of GFLs (5-7) This thesis further explores the emerging view that the combinatorial interactions of the multi-component ligand receptor system with multiple receptor isoforms,...
Ngày tải lên: 09/09/2015, 10:13
Mechanisms and functions of lymphangiogenesis in regulating the immune response and inflammation resolution 2
... through the LN could influence the spatial-temporal distribution of VEGF-A during the course of inflammation and, as a consequence, modulate the remodeling of cortical and medullary sinuses As other ... of the LN The heparin-binding carboxyl-domain of the predominant VEGF-A isoform, VEGF164 may bound the molecule to the extracellular matrix and limit its access deeper into the LN via the reticular ... indispensable for the occurrence of lymphangiogenesis in µMT LNs, it is unlikely that they were the only cells driving the process Depletion of monocytes and macrophages by the use of AFS98 MAb inhibited...
Ngày tải lên: 09/09/2015, 18:48
Mechanisms and functions of lymphangiogenesis in regulating the immune response and inflammation resolution 1
... reabsorbed at the venous side of the capillary bed, where the colloid osmotic pressure of the blood exceeds the blood pressure The main function of the lymphatic vasculature is to return the remaining ... and so forth The mouse isoforms are one amino acid residue shorter than the corresponding human isoform and they are denoted as VEGFA120 and so forth Human VEGF-A121, VEGFA165, VEGFA189 and their ... splicing of human VEGF-C Although the identification of short VEGF-C splicing isoforms (VEGF-C62, VEGF-C129 and VEGF-C184) has been recently reported, the functional activity of these isoforms remains...
Ngày tải lên: 09/09/2015, 18:48
Expression pattern and functions of dihydropyrimindase like 3 in the rodent microglia
... EXPRESSION PATTERN AND FUNCTIONS OF DIHYDROPYRIMIDINASE LIKE-3 IN THE RODENT MICROGLIA JANANI MANIVANNAN, M.Sc A THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY DEPARTMENT OF ANATOMY YONG ... Further, Dpysl3 knockdown in activated microglia altered the expression of proinflammatory cytokines such as TNF-α and IL-1β and inflammatory mediators including iNOS and NO and the migratory and ... receptors) and elicits the activation of signaling cascades thereby resulting in microglial activation (Bamberger and Landreth, 2001; Doens and Fernandez, 2014) Excessive secretion of proinflammatory...
Ngày tải lên: 12/09/2015, 11:24
A study of the functions and politeness of the discourse marker ORH in spoken singapore mandarin
... newcomer to the field, it is furthermore often very difficult to find the bits and pieces that constitute an original model of the meanings and functions of discourse particles Moreover, the studies ... STUDY OF THE FUNCTIONS AND POLITENESS OF THE DISCOURSE MARKER “/ORH/” IN SPOKEN SINGAPORE MANDARIN 江滨 JIANG BIN (B.A Hons, NUS) 新加坡国立⼤大学中⽂文系 北京⼤大学中国语⾔言⽂文学系 双学位硕⼠士(研究)学位论⽂文 A THESIS SUBMITTED FOR THE ... function is to facilitate the process of interpreting the coherence relation(s) between a particular unit of discourse and other, surrounding units and/ or aspects of the communicative situation.14...
Ngày tải lên: 26/09/2015, 10:13
Investigations on the tissue distribution, localization and functions of brain enriched leucine rich repeats (LRR) containing proteins AMIGO AND ngr2
... number of proteins, and these could be divided into seven subfamilies based on Chapter1 Introduction the consensus sequences of the repeats, its species origin and the cellular localization (Kobe and ... the amino acid level between AMIGO to AMIGO-2 and AMIGO-3 is around 50% The most conserved regions between the three proteins are the LRR domain, the transmembrane region, and some parts of the ... group of endoplasmic reticulum associated protein whose functions are unclear All three isoforms of Nogo share the same C-terminus region The topology of Nogo-A has remained controversial but the...
Ngày tải lên: 08/11/2015, 17:08
Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... case of MZ with mirror-imaging of AC in the literature In this case, we describe the second case of MZ with mirror-imaging of AC and discuss the possible clinical implications First, Helland and ... lack of systematic monitoring and follow-up Therefore, a large percentage of patients with AC are probably undiscovered Mirror images, on the other hand, are present in approximately 25% of MZ Therefore, ... consider that it is mandatory to monitor the counterpart of the symptomatic patient with AC as early as possible, irrespective of the absence of symptoms Conflict of Interest The authors have declared...
Ngày tải lên: 25/10/2012, 11:00
Báo cáo y học: "Aplasia and Agenesis of the Frontal Sinus in Turkish Individuals: A Retrospective Study Using Dental Volumetric Tomograph"
... craniotomy because of the proximity of the sinus to the orbit and the anterior skull base [5] The frequency of bilateral absence of the frontal sinus has been reported in 3-4% to 10% of several populations ... reliability between observers and was 0.86 Fig Unilateral absence of the frontal sinus; on the right, the absence of the frontal sinus, and on the left, the limited aeration of the frontal sinus; axial ... a metopic suture, the frontal sinuses are small or absent [8-10] The form of the face and forehead in the presence of a metopic suture conforms to the evolutionary trend of the skull [30] In...
Ngày tải lên: 25/10/2012, 11:04
Báo cáo y học: " Post-traumatic glioma: Report of one case and review of the literature"
... occurrence of the tumor corresponded exactly one to the other; and (4) there was a more than one year interval between trauma and the appearance of the tumor As regards the pathogenesis of post-traumatic ... time interval between trauma and the appearance of the tumor of at least year, a longer latent period increasing the likelihood of a causal relationship The presence of the tumor must be proved histologically ... at the time of the trauma demonstrating significant injury and the follow-up scans demonstrating tumor at the same site4 With the routine use of CT and magnetic resonance imaging (MRI), some of...
Ngày tải lên: 25/10/2012, 11:48