... parts of the structure also contain hydrogen bonds Several structures have been determined independently by different groups and the structures appear to be in good agreement The structure of ImI ... three-dimensional structure of the ribbon disulfide bond isomer of AuIB, where the connectivities are CysI-CysIV and CysII-CysIII, with the disulfide bonds shown in blue importance of this element of structure ... that the diversity of conotoxin primary structures is likely to increase, and this will aid in the elucidation of structureactivity relationships and in the characterization of the nAChR subtypes...
Ngày tải lên: 19/02/2014, 12:20
... Superposition of structure models of the ADP-EcODC complex in crystal and solution The crystal structure of 2q28 is shown in ribbon and line style in deepsalmon, the solution structure model of ADP-ThDP-EcODC ... 369–564) [5] (Fig 2A) The overall structure of the monomer is highly similar to that of ˚ OfODC (rmsd 0.62 A for 488 superimposed Ca atom pairs) The locations of the cofactor ThDP and the activator ... c-carboxyl group of the side chain of residue D302, the d and x nitrogen atoms of the guanodino group of R158 interact with the hydroxyl groups of ribose, and the main chain nitrogens of K220 and...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Studies on structure–function relationships of indolepyruvate decarboxylase from Enterobacter cloacae, a key enzyme of the indole acetic acid pathway ppt
... integral of with respect to the indole protons is consistent with the occurrence of the enol form of indolepyruvate (Fig 1) In the course of the establishment of the equilibrium % 85% of the enol ... constants of reconstitution, calculated from the corresponding progress curves, on the concentration of ThDP (Fig inset) is indicative of a two-step mechanism of cofactor binding as Ó FEBS 2003 Structure function ... sequence of the purified enzyme (Met-Arg-Thr-Pro-Tyr-Cys-Val-Ala) is identical to that of the nucleotide sequence of the EcIPDC gene (DCIP_ENTCL) Fig pH dependence of the oligomeric state of EcIPDC...
Ngày tải lên: 08/03/2014, 02:20
Báo cáo khoa học: Structure–activity relationships of fowlicidin-1, a cathelicidin antimicrobial peptide in chicken docx
... Solution structure of fowlicidin-1 (A) Ribbon stereo-diagram of the restrained minimized average structure of fowlicidin-1 (B) Stereo-diagrams of the backbone trace of the 20 lowest energy structures ... Journal compilation ª 2006 FEBS Y Xiao et al Structure activity relationships of fowlicidin-1 Because of adoption of a well-defined structure in the presence of TFE or SDS, subsequent NMR experiments ... 2582 Results Solution structure of fowlicidin-1 To determine the secondary structure of fowlicidin-1, CD spectroscopy was performed in increasing concentrations of the structure- promoting agents...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo toán học: " Structure-property relations of co-doped bismuth layer-structured Bi3.25La0.75(Ti1-xMox)3O12 ceramics" pptx
... conductivity of BLT and BLTM ceramics measured at frequencies of 1, 50, and 100 kHz is shown in Figure The conductivity values of BLTM were lower than those of undoped BLT ceramic regardless of measurement ... substitution by a replacement of volatile Bi with rare earth or other metal oxide additives is often necessary for ferroelectric property improvement For example, ions of La [5], V [6], Nd [7], and ... orthorhombic structure similar to those found in the powders It could be seen from the XRD patterns of samples with high MoO3 doping content (≥0.05 mol) that X-ray intensities of a particular set of planes,...
Ngày tải lên: 20/06/2014, 20:20
Structure property relationship of crystalline poly(lactic acid)s DFT DFPT studies and applications
... properties of PLA are determined by the polymer primary structures, conformations, the crystal structures and the degree of crystallinity Hence, a study on the relationship of structure and property ... chain primary structures, conformations and packings; crystal structures and the degree of crystallinity etc Hence, an understanding on the relationship of structure/ morphology and property is ... 1.272 g/cm3, observed heat of fusion of beta sample 61 J/g, calculated heat of fusion of a beta crystal 124 J/g) [77] -form: The existence of a third crystal modification of PLLA or the form has...
Ngày tải lên: 09/09/2015, 18:56
Structure function relationships of variegin a novel class of thrombin inhibitors
... Identification of thrombin inhibitors from salivary gland extract of female tropical bont tick, Amblyomma variegatum 2.3.1.1 2.3.1 Protein sequence analysis 74 Structure- function relationships of variegin ... Effect of pre-incubation times on activities of peptides 116 3.3.6 Loss of MH22 activity on prolonged pre-incubation 119 3.4 Discussion 127 3.5 Summary 134 Chapter four: The structure of thrombin-s-variegin ... glands of Amblyomma variegatum, the tropical bont tick 55 Figure 2.2 Pictures of Amblyomma variegatum 55 Figure 2.3 Purification of variegin isoforms by RP-HPLC 72 Figure 2.4 Amino acid sequence of...
Ngày tải lên: 14/09/2015, 14:11
Understanding structure mechanical property relationship of breast cancer cells
... metastasis and cell mechanics In view of the importance of structure- property relationship of cancer cell mechanics, we will then review the components and structures of cells including cytoskeleton, ... square cross section area of 10 μm × 10 μm 38 Fig 3.2 Diagram of the PBS column-based microfluidic system 39 Fig 3.3 Plot of a distance-to-origin profile of a single typical MCF-7 ... and mechanical properties of cancer cells Before we attempt to understand the structure- property relationship of cancer cells, we will first take a look at the structure of a eukaryotic cell Fig...
Ngày tải lên: 14/09/2015, 08:48
Time and performance a three part study examining the relationships of job experience, organizational tenure, and age with job performance
... production, etc.) of performance Fifty-one of the samples were of white collar employees, 20 of blue collar employees, and 11 of medical employees (e.g., nurses, medical aids, etc.) Six of the studies ... samples were of white collar Page 18 Time and Performance CAHRS WP 01-05 employees, 12 were of blue collar employees, eight samples were of mixed groups of employees, and two were of police officers ... Thirty-seven of the samples used “hard” measures of performance; 120 samples used “soft” measures, 115 of which were supervisory ratings Ninety-seven of the correlations were from samples of white-collar...
Ngày tải lên: 11/09/2013, 11:44
Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
... recruitment of MOF to recently transcribed regions, especially at the 3¢ ends of genes where H3-K36me3 is enriched [128] In mammalian cells MOF also exists as part of a separate MOF–MSLv1 complex ... modulation of chromatin structure and transcription by nucleosome binding properties of PARP-1 Cell 119, 803–814 111 Ryoji M & Worcel A (1985) Structure of the two distinct types of minichromosomes ... borders of active genes within polytene chromosome puffs [78] One of the proposed mechanisms of BE function involves the recruitment of chromatin modifying complexes that create islands of active...
Ngày tải lên: 14/02/2014, 18:20
Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
... KIND2-binding specificity of residues 702–744 of MAP2, we performed a pulldown assay of combinations of EGFP-fused KIND1 or KIND2 of v-KIND with GST-fused CD2-1-6-1 or CD2-1-6-2 of MAP2 We successfully ... series of GST-fused deletions of the CD2-1 region (Fig 3E) and examined the interactions between bacterially expressed proteins of these subregions (Fig S1C) and 1654 Fig Of all members of the ... full-length v-KIND; DKIND1, deletion of KIND1; DKIND2, deletion of KIND2; DKIND1 + 2, deletion of both KIND1 and KIND2; DRasN, deletion of RasN; DGEF, deletion of RasGEF; KIND1, KIND1 domain; KIND2,...
Ngày tải lên: 14/02/2014, 19:20
Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt
... and A Patel of cell fate Leukemias associated with loss -of- function or gain -of- function variants of MLL1 are prime examples of the importance of maintaining the enzymatic activity of MLL1 under ... channel that divides a pair of acidic lobes, one of which is composed of residues from the SET-I region and the other of residues from the SET-C and post-SET regions Lysine of histone H3 is inserted ... interaction to the KIX or CREB-binding domain of CBP [31] The KIX domain of CBP is a structural platform that is capable of binding several different families of transcriptional activators [30], and...
Ngày tải lên: 16/02/2014, 14:20
Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): structure–function relationships docx
... Ding et al Structure reactivity–function study of GIF A1 B1 A2 B2 Fig (A1) and (A2) Simulated structure of the b-domain of rlMT2 (B1) and (B2) Predicted structure of the b-domain of hGIF Panels ... domains The progress of structural studies on GIF has mainly been made using NMR and molecular dynamics simulation Structure of the a-domain of GIF The structures of the a-domain of rat GIF and hGIF ... contribute to the dynamics of the b-domain of hGIF However, the structure of the b-domain of hGIF remained unsolved by NMR spectroscopy because insufficient amounts of medium-range and long-range...
Ngày tải lên: 16/02/2014, 15:20
Tài liệu Body Size: The Structure and Function of Aquatic Ecosystems pptx
... G H I L D R E W is Professor of Ecology in the School of Biological and Chemical Sciences at Queen Mary, University of London D A V I D G R A F F A E L L I is Professor of Environmental Science ... roles of different kinds of organisms in the flux and storage of elements in ecosystems The total biomass per unit area, W, is simply the sum of the body mass of all individuals For organisms of ... set of traits, such as age and size at first reproduction, number and size of offspring, inter-clutch interval, and juvenile and adult survival The effects of changes in the magnitude of each of...
Ngày tải lên: 17/02/2014, 19:20
Tài liệu Personal Relationships of Dependence and Interdependence in Law pdf
... regard to the development of a culture of ethics Development of a Culture of Ethics The development of an ethical community of professionals, of commercial actors, or of bureaucrats does not involve ... between relationships of dependence and relationships of interdependence As can the intervention of powerful third parties Third-Party Involvement In managing the risk of exploitation, it is often ... example of the concept of fiduciary obligations involves an executor of an estate appointed to manage property “for the good of heirs who are too young to manage the assets themselves Of course,...
Ngày tải lên: 18/02/2014, 05:20
Tài liệu Báo cáo khoa học: Structure and function of plant aspartic proteinases pptx
... representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain, blue; C-terminal domain, red) (C) Model structure of the PSI domain of cardosin A based on the crystal structure ... form of cyprosin was processed in different isoforms by the excision of the prosegment and of most of the PSI [21] Conversely to what has been found in vivo [31], heavy and light chains of the ... removal of the internal Ó FEBS 2004 Plant aspartic proteinases (Eur J Biochem 271) 2069 Fig Ribbon representation of the crystal structures of cardosin A (A) and prophytepsin (B) (A) Structure of...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: a-Conotoxins as tools for the elucidation of structure and function of neuronal nicotinic acetylcholine receptor subtypes doc
... (2001) Crystal structure of participate in the formation of EpI-resistant a7 receptors, or an ACh-binding protein reveals the ligand-binding domain of that the functional properties of the nAChR ... found in cone snail venoms Identification of further selective peptides, together with the investigation and understanding of their structure- activity relationships, may start to provide a rational ... of the DNA of different Conus species has already revealed a large number of a-conotoxin sequences [45] and the identification of further specific nAChR ligands is likely The advantage of a molecular...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Evolutionary relationships of the prolyl oligopeptidase family enzymes docx
... multiple sequence alignment of the 79 selected sequences was constructed by a combination of T-COFFEE and CLUSTALX programs [14,15] A structure based sequence alignment of pig POP (1QFS) and human ... be of Ó FEBS 2004 Evolutionary relationships of the POP family enzymes (Eur J Biochem 271) 2711 Fig The neighbor-joining tree of POP family enzymes Protein sequences were aligned with T-COFFEE ... was supported by National Technology Agency of Finland and Ministry of Education of Finland (to J I V.) We wish to thank Prof Dan Larhammar, University of Uppsala, for his advice and extremely helpful...
Ngày tải lên: 19/02/2014, 13:20
Tài liệu Báo cáo khoa học: Cold survival in freeze-intolerant insects The structure and function of b-helical antifreeze proteins pdf
... (A) Overlap of X-ray structure with °C NMR structure using the main chain of residues Ser12fiThr70 in the structure alignment (B) Overlap of the X-ray structure with the 30 °C NMR structure using ... chain of residues Ser12fiThr70 in the structure alignment (C) Overlap of X-ray structure of TmAFP with the NMR structure determined at 30 °C using the main chain of residues Gln1fiGly80 in the structure ... Comparison of the X-ray structures of sbwAFP isoform 337 with CfAFP-501 The structures are shown as smoothed, Ca traces, with the structure and PDB code shown below each panel (A) Overlap of isoform...
Ngày tải lên: 19/02/2014, 16:20