structure of the capstone project report

... TRANSLATION ? ?The chart of temperature contour lines in dry season (in November) reveals that the mass of heated water approached close to the southeast of the port or the breakwater and the coast The ... in the ecosystem as a result of the changes in the organisms directly affected) 40 The direct effects of thermal discharges on the water environment include: change to the temperature regime of ... significant elevation of over 360 meters to the north of Tay Yen Village and to the south of the Plant The elevations range from 240 meters to 310 meters to the southwest of the plant (Figure 3.3)

Ngày tải lên: 30/04/2022, 13:28

... amide groups of Ile128 and Arg129. Despite these differences in the coordination of the res- idues in the tip, the fold of the loop is strikingly simi- lar. The rmsd for the Ca atoms of the residues ... conserved. The LL residues of the LLR sequence are important for the stability of the hydrophobic core below the ade- nine group. Fig. 8. A stereoview of the conformation shift of the KMSKS loop. In the ... inhibition of the enzyme. The pos- sibilities for design of a competitive inhibitor are also discussed. These structures exhibit a new structural feature of the CP domain. In one of the complexes, the

Ngày tải lên: 06/03/2014, 22:21

... regrowth upon the optic nerve crush, and also expressed in the germinal neuroepithelium of retina, which generates new neurons throughout the lifespan of the fish [11]. The cloning of the RICH proteins ... orientation of 3¢-AMP when bound to the catalytic domain of RICH. (F) Mapping of the chemical shift changes due to the adenine group of 3¢-AMP on the RICH structure. Fig. 6. Catalytic site of RICH. ... 1600–1609 ª 2007 The Authors Journal compilation ª 2007 FEBS 1601 Results Structure of the RICH catalytic domain We determined the structure of the 24 kDa catalytic fragment of goldfish RICH protein

Ngày tải lên: 07/03/2014, 10:20

... high accuracy, shows clearly the influence of cryo-cooling, which is manifested in shrinkage of the molecule and lowering the volume of the unit cell In the structure of the complex, two acarbose ... and discussion Description of the structures There is one molecule in the asymmetric unit of both structures composed of a single domain consisting of 14 helices, 12 of them forming an (a ⁄ a6) ... which confirms that the deviation of torsion angles from ideal geometry of these two residues is an intrinsic feature of the structure In Glu1.1 there is another residue, Ser305 in the generously

Ngày tải lên: 07/03/2014, 12:20

... towards the interior of the protein. The space that in the wild-type molecule is occupied by the large hydrophobic side chain of Fig. 3. Structure ensemble of HPr(I14A). The average structure of the 10 ... was computed as the ratio of the s tandard deviations of the chemical shifts of the amide nitrogen and p roton nuclei. Results Determination of the three-dimensional structure of HPr(I14A) To allow the comparison ... used for the calculations. Therefore, we recalculated the structure of the w ild-type protein on the b asis of the restraints used previously [15] with the same protocol used here for the mutant

Ngày tải lên: 07/03/2014, 16:20

... with domains A and C of the other subunit. In contrast, the TVA-II group dimer attaches the B domain to an N-terminal domain of the other subunit, which restricts the size of the B domain (Fig. ... between the long B-domain extension of CDase (His251, Fig. 7) and the N-terminal domain of the other subunit of the TVA-II dimer (Tyr45¢). It has been suggested that the N-terminal domain of the ... the loops at the opposite barrel end. The lengths of the b-strands in the barrel vary from two (b14) to seven (b11) residues. As in other enzymes of family no. 13, the regularity of the CDase TIM

Ngày tải lên: 08/03/2014, 02:20

... Cc of Asp and Cd of Glu, and Og of Tyr Positive unit charges were added at the following atoms: Nt of the N-terminus, Nf of Lys, Cf of Arg, and Nd or Ne of His (depending on the position of the ... 42–44) The secondary structure of RIIa D/D was determined from the coordinates of the ensemble of 24 structures using the program MOLMOL [27] For both helices I (I¢) and II (II¢) the beginning of the ... shows the van der Waals model of the top face of the best structure of RIIa D/D in the region )1 to 44 This view is generated by rotating the orientation of RIIa D/D of Fig 4A by 90° about the

Ngày tải lên: 08/03/2014, 22:20

... two factors: (a) the overall similarity of the enzymatic part, and (b) the variability of the angle of approach of the inhibitor relative to the catalytic cleft of the enzyme The latter factor ... out of the catalytic cleft The angle of approach, calculated in the way described above, has the lowest value for the tetragonal form of the chagasin–cathepsin B complex and the highest for the ... chagasin–cathepsin L complex (Table 3) The difference of 9° between these complexes may be correlated with the variation of the rate of binding and affinity for chagasin of these enzymes On the other

Ngày tải lên: 16/03/2014, 04:20

... relative orientations of the a and b domains. In one struc- ture, the catalytic cysteines face each other; in the other, the catalytic residues of the a domain face away from the a¢ domain. The crystal structures ... mm of monomers at 30 °C. Most of the 1 H- 15 N HSQC signals of the dimeric form of PDI-bb¢ coincide with the signals of the monomeric form or are weak as a result of the high molecular weight of ... and the crystal structure of human ERp57-bb¢ [19] is 4.5 A ˚ for 209 amino acids (Z = 14.9). A comparison of the b domain in our PDI-bb¢ structure with the reported solution structure of the

Ngày tải lên: 16/03/2014, 04:20

... binds to the core of the other in a manner similar to that in which helix 6 binds to the core of the structure in the mono- meric solution structure (Figs 3A and 4). The two conformers in the crystal ... Stereo views of the solution and crystal structures of DnaG-C. (A) Superposi- tion of the backbone atoms of residues 447–581 of the 20 NMR conformers of DnaG-C representing the NMR structure (Table ... analysis of linker residues and of residues in the C-terminal domain of B. stearothermo- philus DnaB confirmed the importance of residues in these parts of the protein [3,16]. Unlike in the wild- type

Ngày tải lên: 16/03/2014, 12:20

... protein via the distal surface of v. The base of the clamp-loader complex has an open C-shaped structure, and the shape of the v:w com- plex is suggestive of a loose docking within the crevice ... but, like the d and d¢ subunits of the clamp-loader, neither v nor w contain any of the functional elements required for nucleotide binding. The topology of the w subunit resembles that of the bacterial ... the v:w heterodimer onto the clamp-loader. The structure of the clamp-loader complex is such that there is a prominent gap in the C-shaped base of the structure, between the d and d¢ subunits.

Ngày tải lên: 16/03/2014, 16:20

... site on the extracellular domain. The second step will then be the deposition of the ligand into the TM pocket causing the conformation change of the receptor and triggering the coupling of the receptor ... monitoring the conformation movement and defining the final conformation of the eLPs. These studies were limited to the three eLP domains. The conformation of the eLPs in the simulated reduced form of the ... further definition of the ligand recognition pocket on the extracellular side of the receptors. This has become a major obstacle to the further understanding of the molecular mechanism of the

Ngày tải lên: 16/03/2014, 18:20

... shield the active site pocket by occupying the position corresponding to the lid-loop. To better understand the significance of the absence of the lid-loop sequence and the presence of the extra ... present in most other GGTs at the C-terminal region of the L-subunit. In E. coli GGT, upon autocatalytic cleavage of the peptide bond on the N-terminal side of Thr391, the C-terminal segment of the newly ... GGT. Here, we report the crystal structure of B. subtilis GGT in complex with glutamate, a product of the enzymatic reaction, at 1.95 A ˚ resolution, revealing the unique structure of the catalytic

Ngày tải lên: 22/03/2014, 21:20

... European Union within the framework of the Pilot Project on Transatlantic Methods for Handling Global Challenges The contents of this report are the sole responsibility of the authors and cannot ... this report, which makes evaluation of the impact of the pledges hard to assess Furthermore there appear to be lapses in the adherence to these pledges within Europe, and evidence that they are ... Encourage 25 TheFoodProfiler is a method of evaluating the nutritional quality of foods according to their potential to ‘rebalance’ or ‘unbalance’ the diet (see http://thefoodprofiler.com/) Table...

Ngày tải lên: 18/02/2014, 21:20

... committees of both VI The Constitution Project Members of The Constitution Project s Task Force on Detainee Treatment the State Bar of Texas and as the chairman of the Automation Subcommittee of the ... report on the CIA’s treatment of detainees • The Report of the Special Task Force on Interrogation and Transfer Policies • The CIA Office of the Inspector General (OIG) reports on the deaths of Gul ... secret if they involve the participation of hundreds or thousands of people While the Pentagon controlled the narrative completely at the beginning, The Constitution Project 27 The Report of The Constitution...

Ngày tải lên: 08/03/2014, 04:22

... Strategy of business diversification Combination of the strengths of finance with the threats of market and the intrinsic limitations of the business in the SWOT matrix will help us to formulate the ... analyze the operating environment outside the organization The goal of the analysis is the awareness of opportunities from which the business environment should capture, at the same time as the threats ... technology of Viettel, raising the level of transmission up to 2-3 times of the basic design of the GSM technology In combination with the unique locations of stations, each transceiver station of Viettel...

Ngày tải lên: 28/06/2014, 00:20

... firms to match the proposed plan with the external environment; It is in the direction of future actions  Consider as the state of art in business administration 1.1.3 Types of strategy: Corporate ... competitiveness and determines the optimal solutions for stabilization and development of the Group  However, because of limits on theoretical knowledge as well practice of the group’s members ourselves, ... period of 20112015  Subject & Scope of the study - Subject: Viettel group & other competitive companies in the mobile telecommunication industry - Scope: Basing on specific statistics on the macro...

Ngày tải lên: 28/06/2014, 00:20

... Also, the of phrase can be used to express the subject or object relation: The bus arrived - the arrival of the bus Someone imprisoned the murderer - the imprisonment of the murderer ... concord and (for the most part) other kinds of congruence with the rest of the sentence outside the noun phrase This is exemplified in: The only girl in this class is hardworking All of the beautiful ... - the four legs of the table However, some are relatable to ‘be’ sentences: London is a capital the capital of London The news was the team’s victory - the news of the team’s...

Ngày tải lên: 23/07/2014, 14:20

... according to changes of the market on the basis of the calculation of the actual costs, the analytical reports of the average rates of the inputs and outputs to ensure that the gap of the interest rates ... with the efforts of the whole staff of NaviBank Hai Phong, the financial capability of the branch has been strengthened - The total assets is always higher the operating budget - The unity of the ... influence of the capital providers 38 - Power of the State Bank of Viet Nam: the banking system in general and the banks in particular, have been subjected to the impact created by the policies of the...

Ngày tải lên: 26/03/2015, 10:59

... Duration of this stage is about 15% of the total time of the project, the amount of capital to use is about 0.2% of the total capital of the project The main stages are: - Operation with a capacity of ... yet profitable The longer the investment period (about 60% of the time project) is, the more accumulation of capital is, the greater losses But the time of investing depends on the quality of investment ... in the perspective of its impact on the project, but the project' s impact on the economy at the macro perspective such as socio-economic benefits, the project' s impact on the development of the...

Ngày tải lên: 12/05/2016, 10:46