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structure function and nutritional requirements

Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc

Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc

Báo cáo khoa học

... Analytical enzymes and enzyme substrates were specied in previous papers [1518] All other chemicals were of reagent grade and obtained from Sigma and Fluka Preparation of apo-Cc StP and apo-Ec MalP ... citrate and 0.1 M cysteine hydrochloride, in short, the resolution buffer Various pH values between 5.0 and 8.0 were tested, and a pH of 7.0 was chosen (see below) Prior to the resolution, CcStP and ... R226A and R242A mutants (Table 1), all enzymes were stable for h in the presence of mM potassium phosphate and potassium sulphate Reconstitutions with PLP of apo-Cc StP and mutants thereof, and...
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Báo cáo khoa học: Serpins 2005 – fun between theb-sheets Meeting report based upon presentations made at the 4th Interna-tional Symposium on Serpin Structure, Function and Biology (Cairns, Australia) doc

Báo cáo khoa học: Serpins 2005 – fun between theb-sheets Meeting report based upon presentations made at the 4th Interna-tional Symposium on Serpin Structure, Function and Biology (Cairns, Australia) doc

Báo cáo khoa học

... the mouse, fly and worm, and more exciting discoveries are no doubt on the way On the other hand, the function of plant serpins represents an obvious deficiency in our global understanding of the ... crystallography and this meeting proved no exception; in addition to published work, 10 unpublished serpin structures were presented affording major new insights into serpin function and providing ... serpin function and dysfunction in the coagulation cascade In a related talk, Daniel Johnson (Cambridge Institute for Medical Research, UK) provided an elegant structural explanation for dysfunction...
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A study on structure, function and diachronic evolution of chinese extended middle construction

A study on structure, function and diachronic evolution of chinese extended middle construction

Y - Dược

... Yang Lili and Wu Yayun, for their friendship and the happy days we have been together Finally, I would like to thank my parents, my sister and brother for their love, understanding, and patience ... intriguing semantic relations and syntactic features have prompted many scholars debating its particularity and intrinsic properties This study explores the structure, function, and historical developments ... descriptive and illustrative context where Chinese extended middle construction emerges and put forwards that this construction is a double-topic nested structure The issue of how its form and meaning/function...
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Tài liệu Cognitive function and brain structure correlations in healthy elderly East Asians doc

Tài liệu Cognitive function and brain structure correlations in healthy elderly East Asians doc

Sức khỏe người cao tuổi

... regions based on prior structural and functional imaging data that related structure to cognitive functions of interest (see Greenwood, 2007; Raz, 2005; Reuter-Lorenz and Lustig, 2005 for recent reviews) ... were standardized (z-transformed) and combined into six theoretically motivated composite scores (attention, verbal memory, visuospatial memory, speed of processing, executive functions and language) ... test (Delis et al., 2001), and the Trail Making Test B (Reitan and Wolfson, 1985) Speed of processing was assessed with the TrailMaking Test A (Reitan and Wolfson, 1985) and the Symbol-Digit Modalities...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc

Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc

Báo cáo khoa học

... al [15] determined the structures of E75Q and E75L mutants of rcSHMT and studied their properties However, the structures determined by them were not at high resolution and suffered from a lack ... we determined the structure of E53QbsSHMT and its binary complexes with Gly, l-Ser, l-allo-Thr and ternary complex with Gly and 5-formyl-THF (FTHF) In addition, the biochemical and spectral properties ... bsSHMT (Blue) Y51 and the Schiff base are in the same orientation in E53QbsSHMT and bsSHMT, whereas the orientations of E53, Y60 and Y61 have changed ˚ wild-type and mutant structures is 0.10...
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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc

Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc

Báo cáo khoa học

... hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, but on the other hand ... permeabilized T-cells and induced both local and global Ca2+ signalling in intact T-cells [46] 8-Azido- and 8-NH2-cIDPRE performed similarly (Fig 4) whereas the halogenated compounds 8-Br- and 8-Cl-cIDPRE ... (2005) 4590–4597 ª 2005 FEBS 4591 Second messenger function of cADPR (ADPRC) and thereby induce the formation of cADPR (Fig 2) G-protein coupling and Tyr phosphorylation have been implicated in...
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Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx

Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx

Báo cáo khoa học

... three distinct forms, and the structure of form A solved The enzyme is a homodimer, and the structure shows two domains in the a subunit Ó FEBS 2002 Structure, mechanism and function of prenyltransferases ... molecular dyad axis The seven a helices and six b strands are shown in red and green, respectively, for subunit A, and in magenta and cyan for subunit B, and they are labelled separately The blue ... two a helices (a2 and a3) and four b strands (bB, bA, bD, and bC) as shown in Fig 5A In contrast with the symmetric structure of M luteus UPPS, two protein conformations (open and closed forms)...
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Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot

Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot

Sức khỏe phụ nữ

... pedal and hypobranchial glands in different species of this class In mollusks which lay their eggs in rigid capsules, capsule glands and albumin glands are present in a complex of pallial glands ... development and functioning of the reproductive systems Octopus and cuttlefish females are functionally mature at the end of stage IV (stages V and VI occur at spawning) Female squid are usually functionally ... that during the juvenile phase and through physiological maturation, the gonad and accessory glands function asynchronously At physiological maturity these two organs function synchronously Preliminary...
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Báo cáo khoa học: Structure–function relationship of novel X4 HIV-1 entry inhibitors – L- and D-arginine peptide-aminoglycoside conjugates pptx

Báo cáo khoa học: Structure–function relationship of novel X4 HIV-1 entry inhibitors – L- and D-arginine peptide-aminoglycoside conjugates pptx

Báo cáo khoa học

... aminoglycosides Thus, a new set of poly arginine 6-mer and 9-mer d- and l-aminoglycoside conjugates (APACs) was designed and synthesized, and their cell uptake and antiviral activities were determined We ... HIV-1 Tat responsive element (TAR) RNA binding, NMR structures of TAR–ligand complexes and aminoglycoside–RNA interactions, we have designed and synthesized a set of conjugates of aminoglycoside ... interaction with CXCR4 and compete with its natural ligand SDF-1a to CXCR4 Results Synthesis and chemical characterization of APACs The synthesis of the regioselectively functionalized aminoglycosides...
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Báo cáo khoa học: Effect of valine 106 on structure–function relation of cytosolic human thymidine kinase Kinetic properties and oligomerization pattern of nine substitution mutants of V106 ppt

Báo cáo khoa học: Effect of valine 106 on structure–function relation of cytosolic human thymidine kinase Kinetic properties and oligomerization pattern of nine substitution mutants of V106 ppt

Báo cáo khoa học

... the structure and function of the enzyme by mutating Val106 to amino acids differing in polarity, size and conformation, and subsequently investigating their effect on the quaternary structure and ... [28] The amino acid sequence identity is 34% between dNK and dGK [29], and 47% between dGK and dCK [28], and the structures of dNK, dGK and dCK appeared to be very similar [27,28] Despite the ... glycerol and mM dithiothreitol) with and without 2.5 mM ATP, and incubated on ice for h before storage at )80 °C The enzymes incubated and stored with and without ATP are referred to as the +ATP and...
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Báo cáo khoa học: Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric field effects on structure, dynamics and function of cytochromec doc

Báo cáo khoa học: Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric field effects on structure, dynamics and function of cytochromec doc

Báo cáo khoa học

... demands are imposed on the sensitivity and selectivity of the methodology, which should provide molecular structure and dynamics information In this article, we present the potential of Raman and ... physiological processes of cytochrome c Methodology Raman and IR spectroscopy are molecular structuresensitive techniques, as the frequencies and band intensities of vibrational transitions represent ... field effects on protein structure, dynamics, and function Information provided by surfaceenhanced vibrational spectroscopy Redox proteins immobilized on SAM-coated Ag and Au electrodes are usually...
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Báo cáo khoa học: An asymmetric ion channel derived from gramicidin A Synthesis, function and NMR structure ppt

Báo cáo khoa học: An asymmetric ion channel derived from gramicidin A Synthesis, function and NMR structure ppt

Báo cáo khoa học

... types: those between aHi and NHi+6 (i ¼ 1, 3, and for chain A, and 1, 3, 5, 7, and for chain B); and those between aHi and NHi-6 (i ¼ 10 and for chain A, and 14, 12, 10, and for chain B) These ... The left-handed doublehelix structure transformed into two single-stranded right-handed b-helices with 6.3 residues per turn Whereas the left-handed double b-helix is consistent with the structure ... A and Trp15 of chain B are highly uncertain (with three and four unambiguous data points and R of 0.98 and 0.98, respectively) Fig NOESY spectrum (150 ms) in the region of (F2) 9.7–8.0 p.p.m and...
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Báo cáo khoa học: A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes potx

Báo cáo khoa học: A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes potx

Báo cáo khoa học

... performed to understand the physiological function of the 4-kDa peptide, and suggests that this peptide is involved in the regulation of callus growth and cell proliferation Tertiary structure of the ... °C, and washed twice with Tris/NaCl/Pi for Finally, the cross-reacted bands were detected with alkaline phosphatase substrate (Moss, Maryland) Results and discussion Possible physiological function ... octadecanoid Ó FEBS 2003 Possible function and structure of a 4-kDa legume peptide (Eur J Biochem 270) 1275 Fig Ribbon representation of insulin and the 4-kDa peptide (A) Solution structure of human insulin...
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Chapter 070. Nutritional Requirements and Dietary Assessment (Part 1) docx

Chapter 070. Nutritional Requirements and Dietary Assessment (Part 1) docx

Sức khỏe giới tính

... corn), and roots Combinations of plant proteins that complement one another in biologic value or combinations of animal and plant proteins can increase biologic value and lower total protein requirements ... genetic defects, those having pathologic states with nutritional implications, and developmentally immature infants Many organic phytochemicals and zoochemicals present in foods have health effects ... cirrhosis of the liver Fat and Carbohydrate Fats are a concentrated source of energy and constitute on average 34% of calories in U.S diets For optimal health, saturated fat and trans-fat should be...
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Chapter 070. Nutritional Requirements and Dietary Assessment (Part 2) pps

Chapter 070. Nutritional Requirements and Dietary Assessment (Part 2) pps

Sức khỏe giới tính

... Infants have high requirements for water because of their large ratio of surface area to volume, the limited capacity of the immature kidney to handle high renal solute loads, and their inability ... blunted thirst sensation, and may be taking diuretics Other Nutrients See Chap 71 for a detailed description of vitamins and trace minerals Dietary Reference Intakes and Recommended Dietary Allowances ... be established, the adequate intake (AI), and the tolerable upper level (UL) The current DRIs for vitamins and elements are provided in Tables 70-1 and 70-2, respectively Table 70-1 Dietary Reference...
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Chapter 070. Nutritional Requirements and Dietary Assessment (Part 3) doc

Chapter 070. Nutritional Requirements and Dietary Assessment (Part 3) doc

Sức khỏe giới tính

... α-tocopherol that occurs naturally in foods, and the 2R-stereoisomeric forms of α-tocopherol (RRR-, RSR-, RRS-, and RSS-α-tocopherol) that occur in fortified foods and supplements It does not include ... include the 2S-stereoisomeric forms of αtocopherol (SRR-, SSR-, SRS-, and SSS-α-tocopherol), also found in fortified foods and supplements e As niacin equivalents (NE) mg of niacin = 60 mg of ... pregnancy is confirmed and they enter prenatal care, which ordinarily occurs after the end of the periconceptional period—the critical time for formation of the neural tube Source: Food and Nutrition...
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Chapter 070. Nutritional Requirements and Dietary Assessment (Part 4) potx

Chapter 070. Nutritional Requirements and Dietary Assessment (Part 4) potx

Sức khỏe giới tính

... the healthy individuals of a specific age and sex The types of evidence and criteria used to establish nutrient requirements vary by nutrient, age, and physiologic group The EAR is not useful ... of the U.S Department of Agriculture (USDA), therapeutic diets, and descriptions of the nutritional content of processed foods and dietary supplements The nutrient content in a food is stated ... activity, composition of diet, coexisting diseases, and drugs When only slight differences exist between the requirements for nutrient sufficiency and excess, dietary planning becomes more difficult...
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Chapter 070. Nutritional Requirements and Dietary Assessment (Part 5) pptx

Chapter 070. Nutritional Requirements and Dietary Assessment (Part 5) pptx

Sức khỏe giới tính

... (2) assessing food and dietary supplement intake, and establishing the absence or presence of malnutrition and its possible causes; and (3) planning for the most appropriate nutritional therapy ... body's nutritional needs for growth, maintenance, and other functions Imbalances in nutrient intakes are recognized as risk factors for certain chronic degenerative diseases, such as saturated and ... trans-fat and cholesterol in coronary artery disease; sodium in hypertension; obesity in hormone-dependent endometrial and breast cancers; and ethanol in alcoholism However, the etiology and pathogenesis...
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Chapter 070. Nutritional Requirements and Dietary Assessment (Part 6) pps

Chapter 070. Nutritional Requirements and Dietary Assessment (Part 6) pps

Sức khỏe giới tính

... should be noted and corrected Nutritional monitoring is especially important for patients who are very ill and who have extended lengths of stay Patients who are fed by special enteral and parenteral ... review the adequacy of present and usual food intakes, including vitamin and mineral supplements, medications, and alcohol, as all of these may affect the patient's nutritional status The assessment ... Persons Servings Examples of and Lower: Standard 1600 kcal Moderate: 2200 kcal Higher: 2800 kcal Portion Sizes Fruits, cups 1.5 2.5 Servings Examples and of Lower: Standard 1600 kcal Moderate:...
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