structure function and evolution
A study on structure, function and diachronic evolution of chinese extended middle construction
Ngày tải lên :
09/09/2015, 17:57
... Yang Lili and Wu Yayun, for their friendship and the happy days we have been together Finally, I would like to thank my parents, my sister and brother for their love, understanding, and patience ... intriguing semantic relations and syntactic features have prompted many scholars debating its particularity and intrinsic properties This study explores the structure, function, and historical developments ... descriptive and illustrative context where Chinese extended middle construction emerges and put forwards that this construction is a double-topic nested structure The issue of how its form and meaning/function...
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Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc
Ngày tải lên :
19/02/2014, 16:20
... Analytical enzymes and enzyme substrates were specied in previous papers [1518] All other chemicals were of reagent grade and obtained from Sigma and Fluka Preparation of apo-Cc StP and apo-Ec MalP ... citrate and 0.1 M cysteine hydrochloride, in short, the resolution buffer Various pH values between 5.0 and 8.0 were tested, and a pH of 7.0 was chosen (see below) Prior to the resolution, CcStP and ... R226A and R242A mutants (Table 1), all enzymes were stable for h in the presence of mM potassium phosphate and potassium sulphate Reconstitutions with PLP of apo-Cc StP and mutants thereof, and...
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Báo cáo khoa học: Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species pptx
Ngày tải lên :
16/03/2014, 06:20
... protein and protein–lipid interactions In this review, I describe post-translational regulation of Nox-family enzymes on the basis of three-dimensional structures and evolutionary conservation Structure ... unknown whether the EF-hand-containing Nox subfamilies originated from a common Structure, regulation and evolution of Nox ancestor gene It seems rather likely that EF-hand motifs have been obtained ... enzymes, and not EF-hand-containing oxidases such as Nox5 and Duox, although these two families are found in a variety of species of protostomes and deuterostomes (Fig 3) Thus, Nox5 and Duox...
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Báo cáo khoa học: Serpins 2005 – fun between theb-sheets Meeting report based upon presentations made at the 4th Interna-tional Symposium on Serpin Structure, Function and Biology (Cairns, Australia) doc
Ngày tải lên :
30/03/2014, 20:20
... the mouse, fly and worm, and more exciting discoveries are no doubt on the way On the other hand, the function of plant serpins represents an obvious deficiency in our global understanding of the ... JC (2001) The serpins are an expanding superfamily of structurally similar but functionally diverse proteins Evolution, mechanism of inhibition, novel functions, and a revised nomenclature J Biol ... serpin function and dysfunction in the coagulation cascade In a related talk, Daniel Johnson (Cambridge Institute for Medical Research, UK) provided an elegant structural explanation for dysfunction...
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software visualization visualizing the structure behaviour and evolution of software
Ngày tải lên :
03/07/2014, 21:10
... example its static structure, its concrete and abstract execution, and its evolution In short, they are concerned with visualizing the structure, behavior, and evolution of software Structure refers ... memorize concepts and to exploit analogies to better understand structures or functions Computer scientists use the terms “automata” and “machines” for mathematical models of computation The terms ... “queues”, “files”, “folders”, and “archives” are used to denote data structures For example, a Turing machine is a mathematical model composed of sets, functions, and/ or relations The machine...
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Tài liệu Cognitive function and brain structure correlations in healthy elderly East Asians doc
Ngày tải lên :
14/02/2014, 06:20
... regions based on prior structural and functional imaging data that related structure to cognitive functions of interest (see Greenwood, 2007; Raz, 2005; Reuter-Lorenz and Lustig, 2005 for recent reviews) ... were standardized (z-transformed) and combined into six theoretically motivated composite scores (attention, verbal memory, visuospatial memory, speed of processing, executive functions and language) ... test (Delis et al., 2001), and the Trail Making Test B (Reitan and Wolfson, 1985) Speed of processing was assessed with the TrailMaking Test A (Reitan and Wolfson, 1985) and the Symbol-Digit Modalities...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc
Ngày tải lên :
18/02/2014, 16:20
... al [15] determined the structures of E75Q and E75L mutants of rcSHMT and studied their properties However, the structures determined by them were not at high resolution and suffered from a lack ... we determined the structure of E53QbsSHMT and its binary complexes with Gly, l-Ser, l-allo-Thr and ternary complex with Gly and 5-formyl-THF (FTHF) In addition, the biochemical and spectral properties ... bsSHMT (Blue) Y51 and the Schiff base are in the same orientation in E53QbsSHMT and bsSHMT, whereas the orientations of E53, Y60 and Y61 have changed ˚ wild-type and mutant structures is 0.10...
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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc
Ngày tải lên :
20/02/2014, 01:20
... hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, but on the other hand ... permeabilized T-cells and induced both local and global Ca2+ signalling in intact T-cells [46] 8-Azido- and 8-NH2-cIDPRE performed similarly (Fig 4) whereas the halogenated compounds 8-Br- and 8-Cl-cIDPRE ... (2005) 4590–4597 ª 2005 FEBS 4591 Second messenger function of cADPR (ADPRC) and thereby induce the formation of cADPR (Fig 2) G-protein coupling and Tyr phosphorylation have been implicated in...
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Tài liệu Báo cáo khoa học: Complete subunit sequences, structure and evolution of the 6 · 6-mer hemocyanin from the common house centipede, Scutigera coleoptrata pptx
Ngày tải lên :
20/02/2014, 11:20
... complete molecular structure is known This allows us to compare structure, and intra- and intermolecular evolution of hemocyanins from Myriapoda, Crustacea and Chelicerata Materials and methods Protein ... structural or functional constraints have been imposed on the subunits during evolution Distinct hemocyanin structure and function in Chilopoda and Diplopoda Both the chilopod and diplopod hemocyanins ... in Spirostreptus [15,16] and were lost during the evolution of the Spirostreptidae (Fig 5) The reason for different hemocyanin function and thus structure of Scutigera and Spirostreptus may be...
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Báo cáo khoa học: Evolutionary changes to transthyretin: structure–function relationships ppt
Ngày tải lên :
07/03/2014, 00:20
... amphibians and fish Here, we have shown how evolution of the structure function relationship of a protein can be studied using comparative biochemistry and how hypotheses regarding the structure function ... eightstranded b-sheets, one inner (strands DAGHH¢G¢A¢D¢) and one outer (strands CBEFF¢E¢B¢C) (Fig 2) The interactions predominantly involved are hydrogen bonding between two F strands (F, F¢) and ... chimeric and truncated proteins As structure determines function, and because much current research is associated with human diseases such as amyloidoses, insight into the structure function...
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Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx
Ngày tải lên :
08/03/2014, 22:20
... three distinct forms, and the structure of form A solved The enzyme is a homodimer, and the structure shows two domains in the a subunit Ó FEBS 2002 Structure, mechanism and function of prenyltransferases ... molecular dyad axis The seven a helices and six b strands are shown in red and green, respectively, for subunit A, and in magenta and cyan for subunit B, and they are labelled separately The blue ... two a helices (a2 and a3) and four b strands (bB, bA, bD, and bC) as shown in Fig 5A In contrast with the symmetric structure of M luteus UPPS, two protein conformations (open and closed forms)...
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Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot
Ngày tải lên :
14/03/2014, 16:20
... pedal and hypobranchial glands in different species of this class In mollusks which lay their eggs in rigid capsules, capsule glands and albumin glands are present in a complex of pallial glands ... ventral arm (in squid (Ommastrephes sp and others)) with a short penis Types of Reproductive Strategy and Evolution Differences in reproductive system structure and function (particularly in females) ... development and functioning of the reproductive systems Octopus and cuttlefish females are functionally mature at the end of stage IV (stages V and VI occur at spawning) Female squid are usually functionally...
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Báo cáo khoa học: Structure–function relationship of novel X4 HIV-1 entry inhibitors – L- and D-arginine peptide-aminoglycoside conjugates pptx
Ngày tải lên :
16/03/2014, 06:20
... aminoglycosides Thus, a new set of poly arginine 6-mer and 9-mer d- and l-aminoglycoside conjugates (APACs) was designed and synthesized, and their cell uptake and antiviral activities were determined We ... HIV-1 Tat responsive element (TAR) RNA binding, NMR structures of TAR–ligand complexes and aminoglycoside–RNA interactions, we have designed and synthesized a set of conjugates of aminoglycoside ... interaction with CXCR4 and compete with its natural ligand SDF-1a to CXCR4 Results Synthesis and chemical characterization of APACs The synthesis of the regioselectively functionalized aminoglycosides...
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Báo cáo khoa học: Effect of valine 106 on structure–function relation of cytosolic human thymidine kinase Kinetic properties and oligomerization pattern of nine substitution mutants of V106 ppt
Ngày tải lên :
16/03/2014, 16:20
... the structure and function of the enzyme by mutating Val106 to amino acids differing in polarity, size and conformation, and subsequently investigating their effect on the quaternary structure and ... [28] The amino acid sequence identity is 34% between dNK and dGK [29], and 47% between dGK and dCK [28], and the structures of dNK, dGK and dCK appeared to be very similar [27,28] Despite the ... glycerol and mM dithiothreitol) with and without 2.5 mM ATP, and incubated on ice for h before storage at )80 °C The enzymes incubated and stored with and without ATP are referred to as the +ATP and...
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Cosmology the origin and evolution of cosmic structure coles p , lucchin f
Ngày tải lên :
17/03/2014, 13:34
... Astronomia, Università di Padova, Italy Cosmology The Origin and Evolution of Cosmic Structure Cosmology The Origin and Evolution of Cosmic Structure Second Edition Peter Coles School of Physics & ... both have a strong research interest in theories for the origin and evolution of cosmic structure – galaxies, clusters and the like – and, in many respects, this is indeed the central problem in ... places and in all directions, but also at all times This stronger version of the Cosmological Principle was formulated by Bondi and Gold (1948) and it subsequently led Hoyle (1948) and Hoyle and...
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Báo cáo khoa học: Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric field effects on structure, dynamics and function of cytochromec doc
Ngày tải lên :
22/03/2014, 16:20
... demands are imposed on the sensitivity and selectivity of the methodology, which should provide molecular structure and dynamics information In this article, we present the potential of Raman and ... physiological processes of cytochrome c Methodology Raman and IR spectroscopy are molecular structuresensitive techniques, as the frequencies and band intensities of vibrational transitions represent ... field effects on protein structure, dynamics, and function Information provided by surfaceenhanced vibrational spectroscopy Redox proteins immobilized on SAM-coated Ag and Au electrodes are usually...
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Báo cáo khoa học: An asymmetric ion channel derived from gramicidin A Synthesis, function and NMR structure ppt
Ngày tải lên :
30/03/2014, 15:20
... types: those between aHi and NHi+6 (i ¼ 1, 3, and for chain A, and 1, 3, 5, 7, and for chain B); and those between aHi and NHi-6 (i ¼ 10 and for chain A, and 14, 12, 10, and for chain B) These ... The left-handed doublehelix structure transformed into two single-stranded right-handed b-helices with 6.3 residues per turn Whereas the left-handed double b-helix is consistent with the structure ... A and Trp15 of chain B are highly uncertain (with three and four unambiguous data points and R of 0.98 and 0.98, respectively) Fig NOESY spectrum (150 ms) in the region of (F2) 9.7–8.0 p.p.m and...
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Báo cáo khoa học: A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes potx
Ngày tải lên :
31/03/2014, 07:20
... performed to understand the physiological function of the 4-kDa peptide, and suggests that this peptide is involved in the regulation of callus growth and cell proliferation Tertiary structure of the ... °C, and washed twice with Tris/NaCl/Pi for Finally, the cross-reacted bands were detected with alkaline phosphatase substrate (Moss, Maryland) Results and discussion Possible physiological function ... octadecanoid Ó FEBS 2003 Possible function and structure of a 4-kDa legume peptide (Eur J Biochem 270) 1275 Fig Ribbon representation of insulin and the 4-kDa peptide (A) Solution structure of human insulin...
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cosmology the origin and evolution of cosmic structure, 2nd edition the origin and evolution of cosmic structure
Ngày tải lên :
03/06/2014, 01:49
... Astronomia, Università di Padova, Italy Cosmology The Origin and Evolution of Cosmic Structure Cosmology The Origin and Evolution of Cosmic Structure Second Edition Peter Coles School of Physics & ... both have a strong research interest in theories for the origin and evolution of cosmic structure – galaxies, clusters and the like – and, in many respects, this is indeed the central problem in ... places and in all directions, but also at all times This stronger version of the Cosmological Principle was formulated by Bondi and Gold (1948) and it subsequently led Hoyle (1948) and Hoyle and...
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