structure function and dynamic actions
Tài liệu Báo cáo khoa học: Relationships between structure, function and stability for pyridoxal 5¢-phosphate-dependent starch phosphorylase from Corynebacterium callunaeas revealed by reversible cofactor dissociation studies doc
Ngày tải lên :
19/02/2014, 16:20
... fractions obtained (AC) were characterized by N-terminal sequencing and two parameters of enzyme function distinguishing sensitively between CcStP and EcMalP: (a) apparent substrate afnity and ... Analytical enzymes and enzyme substrates were specied in previous papers [1518] All other chemicals were of reagent grade and obtained from Sigma and Fluka Preparation of apo-Cc StP and apo-Ec MalP ... citrate and 0.1 M cysteine hydrochloride, in short, the resolution buffer Various pH values between 5.0 and 8.0 were tested, and a pH of 7.0 was chosen (see below) Prior to the resolution, CcStP and...
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Báo cáo khoa học: Serpins 2005 – fun between theb-sheets Meeting report based upon presentations made at the 4th Interna-tional Symposium on Serpin Structure, Function and Biology (Cairns, Australia) doc
Ngày tải lên :
30/03/2014, 20:20
... the mouse, fly and worm, and more exciting discoveries are no doubt on the way On the other hand, the function of plant serpins represents an obvious deficiency in our global understanding of the ... crystallography and this meeting proved no exception; in addition to published work, 10 unpublished serpin structures were presented affording major new insights into serpin function and providing ... serpin function and dysfunction in the coagulation cascade In a related talk, Daniel Johnson (Cambridge Institute for Medical Research, UK) provided an elegant structural explanation for dysfunction...
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A study on structure, function and diachronic evolution of chinese extended middle construction
Ngày tải lên :
09/09/2015, 17:57
... Yang Lili and Wu Yayun, for their friendship and the happy days we have been together Finally, I would like to thank my parents, my sister and brother for their love, understanding, and patience ... intriguing semantic relations and syntactic features have prompted many scholars debating its particularity and intrinsic properties This study explores the structure, function, and historical developments ... descriptive and illustrative context where Chinese extended middle construction emerges and put forwards that this construction is a double-topic nested structure The issue of how its form and meaning/function...
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02 three dimensional static and dynamic analysis of structure
Ngày tải lên :
12/01/2014, 21:45
... 1996-2001 The CSI Logo is a trademark of Computers and Structures, Inc SAP90, SAP2000, SAFE, FLOOR and ETABS are trademarks of Computers and Structures, Inc ISBN 0-923907-00-9 STRUCTURAL ENGINEERING ... research papers to understand the theory presented in this book The author has developed and published many computational techniques for the static and dynamic analysis of structures It has been ... Three Dimensional Dynamic Analysis of Structures is included and updated in this book I am looking forward to additional comments and questions from the readers in order to expand the material...
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Optimal security design and dynamic capital structure in a countinous time agency model DEMARZO & SANNIKOV
Ngày tải lên :
12/01/2014, 22:16
... continuous-time capital structure models developed by Leland and Toft (1996), Leland (1998), and others These papers take the form of the securities as given and derive the effect of capital structure on ... 1213-1252 Leland, Hayne E., 1998, Agency costs, risk management, and capital structure, Journal of Finance 53, 1213-1243 Leland, Hayne E., and Klaus.B Toft, 1996, Optimal capital structure, endogenous ... σ and liquidation value L of the project The mix of debt and credit will depend on these parameters, however, as we explore next II Optimal Capital Structure and Security Prices The capital structure...
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Tài liệu Cognitive function and brain structure correlations in healthy elderly East Asians doc
Ngày tải lên :
14/02/2014, 06:20
... regions based on prior structural and functional imaging data that related structure to cognitive functions of interest (see Greenwood, 2007; Raz, 2005; Reuter-Lorenz and Lustig, 2005 for recent reviews) ... were standardized (z-transformed) and combined into six theoretically motivated composite scores (attention, verbal memory, visuospatial memory, speed of processing, executive functions and language) ... test (Delis et al., 2001), and the Trail Making Test B (Reitan and Wolfson, 1985) Speed of processing was assessed with the TrailMaking Test A (Reitan and Wolfson, 1985) and the Symbol-Digit Modalities...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc
Ngày tải lên :
18/02/2014, 16:20
... l-threo- and l-erythro-b-phenyl serine [4–6] It also catalyzes transamination, racemization and decarboxylation reactions [7] SHMT has been isolated and studied from several sources X-ray crystal structures ... al [15] determined the structures of E75Q and E75L mutants of rcSHMT and studied their properties However, the structures determined by them were not at high resolution and suffered from a lack ... we determined the structure of E53QbsSHMT and its binary complexes with Gly, l-Ser, l-allo-Thr and ternary complex with Gly and 5-formyl-THF (FTHF) In addition, the biochemical and spectral properties...
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Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc
Ngày tải lên :
20/02/2014, 01:20
... hypoxanthine) and the diphospho-bridge, as they can be replaced by much simpler ether strands These ether strands mimic the distance between the nucleobase and the diphospho-bridge, but on the other hand ... permeabilized T-cells and induced both local and global Ca2+ signalling in intact T-cells [46] 8-Azido- and 8-NH2-cIDPRE performed similarly (Fig 4) whereas the halogenated compounds 8-Br- and 8-Cl-cIDPRE ... (2005) 4590–4597 ª 2005 FEBS 4591 Second messenger function of cADPR (ADPRC) and thereby induce the formation of cADPR (Fig 2) G-protein coupling and Tyr phosphorylation have been implicated in...
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Báo cáo Y học: Structure, mechanism and function of prenyltransferases docx
Ngày tải lên :
08/03/2014, 22:20
... three distinct forms, and the structure of form A solved The enzyme is a homodimer, and the structure shows two domains in the a subunit Ó FEBS 2002 Structure, mechanism and function of prenyltransferases ... molecular dyad axis The seven a helices and six b strands are shown in red and green, respectively, for subunit A, and in magenta and cyan for subunit B, and they are labelled separately The blue ... distribution of the UPPS and OPPS reactions is that, when the Ó FEBS 2002 Structure, mechanism and function of prenyltransferases (Eur J Biochem 269) 3347 concentration of the UPPS and FPP complex is...
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Reproductive System Structure, Development and Function in Cephalopods with a New General Scale for Maturity Stages pot
Ngày tải lên :
14/03/2014, 16:20
... pedal and hypobranchial glands in different species of this class In mollusks which lay their eggs in rigid capsules, capsule glands and albumin glands are present in a complex of pallial glands ... development and functioning of the reproductive systems Octopus and cuttlefish females are functionally mature at the end of stage IV (stages V and VI occur at spawning) Female squid are usually functionally ... that during the juvenile phase and through physiological maturation, the gonad and accessory glands function asynchronously At physiological maturity these two organs function synchronously Preliminary...
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Báo cáo khoa học: Structure–function relationship of novel X4 HIV-1 entry inhibitors – L- and D-arginine peptide-aminoglycoside conjugates pptx
Ngày tải lên :
16/03/2014, 06:20
... HIV-1 Tat responsive element (TAR) RNA binding, NMR structures of TAR–ligand complexes and aminoglycoside–RNA interactions, we have designed and synthesized a set of conjugates of aminoglycoside ... aminoglycosides Thus, a new set of poly arginine 6-mer and 9-mer d- and l-aminoglycoside conjugates (APACs) was designed and synthesized, and their cell uptake and antiviral activities were determined We ... interaction with CXCR4 and compete with its natural ligand SDF-1a to CXCR4 Results Synthesis and chemical characterization of APACs The synthesis of the regioselectively functionalized aminoglycosides...
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Báo cáo khoa học: Effect of valine 106 on structure–function relation of cytosolic human thymidine kinase Kinetic properties and oligomerization pattern of nine substitution mutants of V106 ppt
Ngày tải lên :
16/03/2014, 16:20
... the structure and function of the enzyme by mutating Val106 to amino acids differing in polarity, size and conformation, and subsequently investigating their effect on the quaternary structure and ... [28] The amino acid sequence identity is 34% between dNK and dGK [29], and 47% between dGK and dCK [28], and the structures of dNK, dGK and dCK appeared to be very similar [27,28] Despite the ... dithiothreitol) with and without 2.5 mM ATP, and incubated on ice for h before storage at )80 °C The enzymes incubated and stored with and without ATP are referred to as the +ATP and –ATP forms, respectively...
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Báo cáo khoa học: Surface-enhanced vibrational spectroscopy for probing transient interactions of proteins with biomimetic interfaces: electric field effects on structure, dynamics and function of cytochromec doc
Ngày tải lên :
22/03/2014, 16:20
... demands are imposed on the sensitivity and selectivity of the methodology, which should provide molecular structure and dynamics information In this article, we present the potential of Raman and ... field effects on protein structure, dynamics, and function Information provided by surfaceenhanced vibrational spectroscopy Redox proteins immobilized on SAM-coated Ag and Au electrodes are usually ... interfacial processes, which, on the other hand, is accessible with the structure- sensitive SERR and SEIRA spectroscopy To probe the dynamics of molecular structure changes during the redox process,...
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Báo cáo khoa học: An asymmetric ion channel derived from gramicidin A Synthesis, function and NMR structure ppt
Ngày tải lên :
30/03/2014, 15:20
... types: those between aHi and NHi+6 (i ¼ 1, 3, and for chain A, and 1, 3, 5, 7, and for chain B); and those between aHi and NHi-6 (i ¼ 10 and for chain A, and 14, 12, 10, and for chain B) These ... The left-handed doublehelix structure transformed into two single-stranded right-handed b-helices with 6.3 residues per turn Whereas the left-handed double b-helix is consistent with the structure ... A and Trp15 of chain B are highly uncertain (with three and four unambiguous data points and R of 0.98 and 0.98, respectively) Fig NOESY spectrum (150 ms) in the region of (F2) 9.7–8.0 p.p.m and...
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Báo cáo khoa học: A possible physiological function and the tertiary structure of a 4-kDa peptide in legumes potx
Ngày tải lên :
31/03/2014, 07:20
... performed to understand the physiological function of the 4-kDa peptide, and suggests that this peptide is involved in the regulation of callus growth and cell proliferation Tertiary structure of the ... °C, and washed twice with Tris/NaCl/Pi for Finally, the cross-reacted bands were detected with alkaline phosphatase substrate (Moss, Maryland) Results and discussion Possible physiological function ... octadecanoid Ó FEBS 2003 Possible function and structure of a 4-kDa legume peptide (Eur J Biochem 270) 1275 Fig Ribbon representation of insulin and the 4-kDa peptide (A) Solution structure of human insulin...
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Báo cáo toán học: "Short term interactions between tree foliage and the aerial environment: An overview of modelling approaches available for tree structure-function model" potx
Ngày tải lên :
08/08/2014, 14:22
... acquisition and use (e.g transpiration and/ or photosynthesis) and study the interactions between these processes and tree architecture; ii) dynamic models aimed at simulating tree architecture dynamics ... result of the interactions between tree structure, function and the environment Such models are structural-functional tree models sensu stricto and should include both instantaneous and delayed tree ... fuel economy and pollutant capture in urban environment [50, 85] The framework of tree structure function models is primarily aimed at understanding tree growth and development Functional-structural...
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Báo cáo khoa học: " Avian reovirus L2 genome segment sequences and predicted structure/function of the encoded RNA-dependent RNA polymerase protein" docx
Ngày tải lên :
12/08/2014, 04:21
... strains of ARV (ARV138 and ARV176) in order to expand the available ARV sequence database, determine sequences of the ARV RdRp protein, and to delineate conserved structure/ function features of ... CSRV, and AqRV GCRV are aligned (Fig 1) Thus, to gain structure/ function information about this key viral-encoded enzyme, ARV, MRV, and AqRV identical amino acids, conservative substitutions, and ... MRV, and AqRV RdRp protein sequences (Fig 1, closed circles) Amino acid identities between ARV λB and homologous MRV λ3 or AqRV VP2 are ~55% and ~42%, respectively (Table 3), suggesting the ARV and...
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Báo cáo y học: " Inhaled salmeterol and/or fluticasone alters structure/function in a murine model of allergic airways disease" potx
Ngày tải lên :
12/08/2014, 11:20
... fluticasone and salmeterol, both separately and in combination, on lung structure and function in allergically inflamed mice Salmeterol alone worsened airways hyperresponsiveness and increased ... epithelial cells containing airway mucin was greatest in the V and S groups and was significantly less in the F and FS groups (Figures and 7) There was a trend for increased PAFS positive cells in ... Groups include naïve mice (N) and OVA sensitized and challenged mice treated with vehicle control (V), salmeterol (S), fluticasone (F), and a combination of fluticasone and salmeterol (FS) Results...
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Báo cáo y học: "Dynamic changes of serum SARS-Coronavirus IgG, pulmonary function and radiography in patients recovering from SARS after hospital discharge" ppt
Ngày tải lên :
12/08/2014, 18:21
... given a routine pulmonary function test (ventilation and diffusion function: SensorMedics 2200 pulmonary function test apparatus, U.S.A.), a chest X-ray examination and serum SARS-CoV specific ... study focused on the dynamic changes in the IgG antibody levels against SARS-CoV and in lung lesions in the discharged but recovering SARS patients as measured by lung function and imaging tests ... acquired immune function, pulmonary function, bones and joints over the course of time At present, there have been few reports about the relationship between the prognosis for recovery and the degree...
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