structure and interpretation of computer programs mit press

Ngày tải lên: 05/04/2014, 01:31

Ngày tải lên: 13/08/2014, 16:20

Ngày tải lên: 12/12/2013, 00:15

... bulk of AcH4-K16 in vivo is likely to be MOF in mammals and Drosophila, and its homologue Sas2 in yeast. MOF is H4-K16 specific and was originally identified in Drosophila as a component of the ... A (1979) Involvement of histone H1 in the organization of the nucleosome and of the salt-dependent superstructures of chromatin. J Cell Biol 83, 403–427. Active chromatin and DNase I hypersensitive ... with binding of both MOF and Tip60 (equivalent to Esa1 in yeast NuA4) [124,130]. However, in human cells depletion of MOF, but not Tip60, results in reduced global levels of AcH4-K16 and defective...

Ngày tải lên: 14/02/2014, 18:20

... (Hamamatsu, Japan) and used in accordance with protocols approved by the Animal Care and Use Committee of RIKEN. Plasmid construction and expression Plasmid construction and expression in Escherichia ... full-length v-KIND; DKIND1, deletion of KIND1; DKIND2, deletion of KIND2; DKIND1 + 2, deletion of both KIND1 and KIND2; DRasN, deletion of RasN; DGEF, deletion of RasGEF; KIND1, KIND1 domain; KIND2, KIND2 ... α -Flag KIND2-Flag Δ GEF-Flag A B Fig. 1. Domain structure of the MAP2-asso- ciated RasGEF v-KIND and its dendritic tar- geting via KIND2 domain. (A) Structures of the v-KIND. KIND1, KIND2, coiled-coil (CC), RasN and RasGEF domains....

Ngày tải lên: 14/02/2014, 19:20

... predicting, measuring and understanding the roles of different kinds of organisms in the flux and storage of elements in ecosystems. The total biomass per unit area, W,is simply the sum ofthe body mass of all ... & Jumars, 1991) and the problems of dealing with extremely small particles. It is reasonable to expect tuning of the size of filtering structures and collect- ing elements to profitable prey size ... detected and the processes that appeared to be important, and (ii) to compare freshwater and marine ecosystems. In Body Size: The Structure and Function of Aquatic Ecosystems, both those questions of...

Ngày tải lên: 17/02/2014, 19:20

... (1990) The structure and function of the aspartic proteinases. Annu. Rev. Biophys. Biophys. Chem. 19, 189–215. 2. Dunn, B.M. (2002) Structure and mechanism of the pepsin-like family of aspartic ... and C-terminal domain in red. (B) Ribbon representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain, blue; C-terminal domain, red). (C) Model structure of ... isoforms by the excision of the prosegment and of most of the PSI [21]. Conversely to what has been found in vivo [31], heavy and light chains of the processed forms of recombinant cyprosin are...

Ngày tải lên: 19/02/2014, 12:20

... determination of the subunit composition of the nAChRs involved has been hindered by the lack of selective ligands and imperfect correlations between the characteristics of native and heterologously expressed ... heterologous expression [2,3]. Coexpression of a7anda8, as well as of a9 and the highly homologous a10 subunit [10] has been shown to generate heteromeric channels with properties distinct from those of ... subunits, and was not reliably expressed in combination with b4 subunits, an a6/a3 chimera consisting of the extracellular ligand-binding domain of the a6 subunit and the transmembrane and intracellular...

Ngày tải lên: 19/02/2014, 12:20

... [31,32,36] and their three- dimensional structures were determined [34,37–40]. In subsequent sections, we describe the structure and dynamics of each protein, and present a comparison of s bwAFP and TmAFPwitheachotherandwithproteinsthathavea similar ... and TmAFPwitheachotherandwithproteinsthathavea similar fold. Structure of sbwAFP and TmAFP The structure of sbwAFP has been determined by X-ray crystallography to 2.5 A ˚ and by NMR at both 30 °Cand 5 °C ... Overlap of X-ray structure with 5 °C NMR structure using the main chain of residues Ser12 fiThr70 in t he structure a lignment. (B) O verlap of the X-ray structure with the 30 °C NMR structure using...

Ngày tải lên: 19/02/2014, 16:20

... were submitted to MALDI- TOF analysis and assigned to distinct subunits. Fig. 1. SDS/PAGE and immunoblotting of S. coleoptrata hemocyanin. About 10 lg of total hemolymph protein (HL) and 3 lgofpurified hemocyanin ... SDS/ PAGE and stained by Coomassie brilliant blue. The two hemocyanin bands were cut out and dispersed. About 100 lg of hemocyanin was used for the immunization of rabbits. For determination of the ... subunits and HcX, plus 6–45 bp of the respective 5¢ untranslated regions and the entire 3¢ untranslated regions. The standard polyadenylation signals (AATAAA) and the poly(A)-tails of different...

Ngày tải lên: 20/02/2014, 11:20

... orm of b strand [18]. The positive bands at » 1675 cm )1 in the amide I r egion of the ROA spectra of b-andj-casein, which originate mainly in the peptide C  O stretch, are characteristic of ... theme of PPII structure and rheomor- phism is explored by a comparative ROA study, supple- mented with DSC, of caseins, synucleins and tau, together with several mutants of a-synuclein and tau ... agreement between our present results and the earlier interpretations of the U VCD spectra of b-andj-caseins (see above) to the fact that t he basis s ets of protein UVCD spectra used in the analysis...

Ngày tải lên: 21/02/2014, 15:20

... model of the role of point of view in problem solving. SUMMARY We have reported here a three pronged approach to the study of problem solving action and report: I) the collected of data ... of data on problem solving and talk about problem solving, 2) development of a process model of these behaviors, and 3) use of coding techniques to extract traces of "critical phenomena" ... types of problem solving phenomena: the changes in the problem solver's organization of the problem ("point of view"), and systematic multl-utterance structures used to express...

Ngày tải lên: 21/02/2014, 20:20

... to grasp yet it is essential for defining precise specifications of what programs do. Like Structure and Interpretation of Computer Programs, by Abelson, Sussman, & Sussman [1, 2], our book ... of Computer Science, and the De- partment of Microelectronics and Information Technology at KTH. We apologize to anyone we may have inadvertently omitted. Copyright c  2001-3 by P. Van Roy and ... improved versions of Java). The kernel language approach Practical programming languages scale up to programs of millions of lines of code. They provide a rich set of abstractions and syntax. How...

Ngày tải lên: 22/02/2014, 06:20

... concentrations of monomer and dimer, respectively. The K d canalsobe expressed in terms of the total mass concentration of protein, [arrestin] total (in mgÆmL )1 ), the mass fraction of monomer, f M , and ... McDowell 2 , W. Clay Smith 2 and Paul A. Hargrave 2,3 1 Department of Biochemistry, University of Western Ontario, London, Ontario, Canada; 2 Departments of Ophthalmology and 3 Biochemistry and Molecular ... phosphorylation of the C-terminus of R* and binding by arrestin. Phosphorylation somewhat decreases the ability of R* to signal transducin. Rapid shut- off of R* signalling is then accomplished by binding of arrestin...

Ngày tải lên: 22/02/2014, 07:20

... of the spectral pressure modes as well as the linkage between the pressure modes and hidden events of the unsteady pressure fields. 6. Synthesis and identification of random pressure field Firstly, ... applications of the Proper Transformations based on both cross spectral matrix and covariance matrix branches to analysis and identification of multi-variate random pressure fields. The random pressure ... section. The fluctuating pressure field can be represented as spatially-correlated multi-variate random processes. Understanding and knowledge of the random pressure field and its distribution is...

Ngày tải lên: 05/03/2014, 14:20

... minidomain and the zinc-binding domain of the zinc finger protein Ynr046w [25] (Fig. 8). The fit of the heavy atoms (Ca, C, and N) from three b-strands and the a-helices of both the closed and the open ... TA, Gargaro AR & Feeney J (1999) Structure and dynamics in solution of the complex of Lactobacillus casei dihydrofolate reduc- NMR structure and function of the eRF1 C-domain A. B. Mantsyzov ... variation of pH in the range between 6.3 and 7.7, of ionic strength between 25 and 100 mm NaCl and of temperature between 278 and 313 K did not lead to any detectable change in the populations of the...

Ngày tải lên: 06/03/2014, 11:20

... helices A V and B V at the surface of domain V. Gly621 and Gly617 are in the area of contact with the 1095 and 2473 regions of 23S RNA. The two helices are facing the ribosome, and the four-stranded ... 666 and 670, within one b-strand of domain V, are also important for interdomain interac- tions. The N-terminal part of the strand interacts with the N-terminal part of helix C G in domain G, and ... occupancy of GDP in the nucleotide-binding site. Therefore, we present here the apo structure of S. aureus EF-G. Overall structure and comparison with previous EF-G structures All five domains of S....

Ngày tải lên: 06/03/2014, 22:21

Ngày tải lên: 07/03/2014, 00:20

Ngày tải lên: 07/03/2014, 05:20

Ngày tải lên: 07/03/2014, 05:20