structure and function of the human body

... cloned into pGEX-4T-2 The KIND domains of Spir-2 and PTPN13 were generated by RT-PCR and inserted into pEGFP-C1 and pGEX-4T-2 The N- and C-terminal regions of the v-KIND KIND2 and the MAP2 CD were ... structural and functional importance of the v-KIND and MAP2 interaction core modules in the regulation of dendrite growth and branching in hippocampal neurons and cerebellar granule cells Further studies ... proteins of these subregions (Fig S1C) and 1654 Fig Of all members of the KIND family of proteins, only KIND2 binds to MAP2 Pull-down assay (PD) of the endogenous MAP2 from cerebellar lysates of P21...

Ngày tải lên: 14/02/2014, 19:20

... conformer of the C-domain (red and blue) on the crystal structure [20] of the complex of human eRF1 (green) and the truncated eRF3 (purple) The superposition was made using the Ca, C¢ and N atoms of the ... on one side of the b-sheet and two on the other side The rmsd of the heavy atoms (Ca, C, and N) of the protein core, when the NMR structures of both conformers are superimposed on the crystal ... between the signal of the HN of Gly337 in the open conformer and the signal of the water protons All of these observations indicate that the loop region of the open conformer has a higher degree of...

Ngày tải lên: 06/03/2014, 11:20

... in the mutant First, there is an increase in the negative charge in the active site and, second, breaking the salt bridge would alter the quaternary structure of the protein and therefore the ... in the ArCMLE1 structure The figure was created from the coordinates of the P212121 structure of ArCMLE1 and of PpCMLE (Protein Data Bank code 1RE5) (B) Water cavity below the active site The ... structure The variation in size and the observed amino acid modification between PpCMLE and ArCMLE suggested important differences between the two enzymes Therefore, the crystal structure of the...

Ngày tải lên: 30/03/2014, 10:20

... STRUCTURE AND FUNCTION OF THE ARABIC VERB Structure and Function of the Arabic Verb is a corpus-based study that unveils the morpho-syntax and the semantics of the Arabic verb ... very indicative, in our opinion, of the adequacy and the basis of this orientation, on the one hand, and the destiny of linguistics, on the other hand Of course, these implications might be too ... constructions The frequency of WA, FA-, LA-, and Ø in front of QAD Frequency of the compound perfect The distribution and frequency of sawfa/saThe frequency of QAD, laʕalla, and rubbamaa The contextual...

Ngày tải lên: 03/04/2014, 12:48

... measuring and understanding the roles of different kinds of organisms in the flux and storage of elements in ecosystems The total biomass per unit area, W, is simply the sum of the body mass of all ... tradition of empirical and theoretical work in biological oceanography and limnology that relates the structure, function and biotic composition of these systems to the body sizes of the organisms ... reproduction, number and size of offspring, inter-clutch interval, and juvenile and adult survival The effects of changes in the magnitude of each of these traits on the others (e.g increased offspring...

Ngày tải lên: 17/02/2014, 19:20

... human body The position of proverbs referring to part of the human body Parts of the human body 21 21 21 The classification of parts of the human body according to position Graduation thesis ... three functions: the function of comprehension, the aesthetic function, the function of education, the words about parts of human body are used to form the meaning of proverbs, therefore, they ... diversified (multiple form) The classification of parts of the human body according to the position In the system of the proverbs, the system of words referring to parts of the human body is divided into...

Ngày tải lên: 12/12/2013, 00:03

... earth The hand of a child - The hand of a lock The heart of a man - The heart of a matter 37 The tongue of a man - The tongue of a shoe The tooth of a person - The tooth of a comb The head of a ... hands of a farm 13 The heel of a person - The heel of the hand 14 One's leg - The leg of a trip 15 One's brain - The brains of a family 16 The bosom of a person - The bosom of the church 17 The ... The head of the page The scar left on one's kin - The scars of war The arm of a person - The arm of jacket 10 One's breast - The chest 11 One's foot - The foot of sock 12 One's hands - The hands...

Ngày tải lên: 18/12/2013, 21:45

... above, the determination of the subunit composition of the nAChRs involved has been hindered by the lack of selective ligands and imperfect correlations between the characteristics of native and ... native and heterologously expressed nAChRs The examples presented above clearly demonstrate the usefulness of a-conotoxins in the determination of the structure and function of native nAChRs, and ... Furthermore, the distance of the projection areas from the cell bodies and the indistinct correlation between subunit mRNA levels and functional surface nAChRs hampers the interpretation of studies...

Ngày tải lên: 19/02/2014, 12:20

... Further examination of the structure and sequence of sbwAFP and TmAFP reveal other similarities (Fig 8C) The panel shows the similarity of the TXT face again, and also reveals the presence of ... changes in the structure of the insect AFPs and to further characterize the TXT face of these proteins, the backbone dynamics of TmAFP and sbwAFP were measured at 30 °C and °C [38,40] Overall, the results ... shown as smoothed, Ca traces, with the structure and PDB code shown below each panel (A) Overlap of isoform 337 with the structure of the longer isoform CfAFP-501 using the main chain of residues...

Ngày tải lên: 19/02/2014, 16:20

... changes the conformation of the other subunit, thereby completely abolishing reaction of SDTG with the second subunit Analysis of the crystal structure of the enzyme in complex with the S-atrazine–GSH ... hydrophobic pocket of domain II of the other monomer, physically anchors the two subunits together at either end of the interface Explanation of the biphasic kinetics An average incorporation of 0.5 mol ... concentration of SDTG, k3 is the maximal rate of inactivation (min)1), and Kd is the apparent dissociation constant of the E:SDTG complex From the data shown in Fig 2, Kd values of 107.9 ± 2.1 lM and 224.5...

Ngày tải lên: 16/03/2014, 16:20

... ago and since then the HAMLET field has widened in scope, acquiring new members and enriching our understanding of the basic principles underlying protein self-assembly and acquisition of new functionality ... radii of HAMLET (Rh = 26.9 A), which is intermediate of the hydrodynamic radii of the acidic molten globule state of a-lactalbumin ˚ (Rh = 20.9 A) and the theoretically extreme expansion state of ... describing the form and function of novel complexes such as HAMLET and ELOA, we have provided new evidence that a loss of native structure can endow proteins and their complexes with distinct and beneficial...

Ngày tải lên: 29/03/2014, 21:20

... 2A) and between the ratio of the length of appressed to non-appressed thylakoid membranes and photon fluence rate (Fig 2B) This suggests that, in the canopy, acclimation of the thylakoid structure ... below 1.4 (Fig B) The leaves examined from levels and were physiologically young and the rates of C0 uptake recorded were from intermediate to high (Fig 2A) The ratio of the length of appressed to ... a lower rate of C0 uptake and an appressed/non-appressed membrane ratio of about In the present study, a tion was found between negative correla- N P and the ratio of the length of appressed...

Ngày tải lên: 09/08/2014, 03:24

... Background The liver sinusoids are lined by endothelial cells that have a unique structure and function essential for hepatic and systemic homeostasis Much of our understanding of the biology of the ... IM and BS conceived of the study IM carried out most of the experimental work and the writing AW and DGL participated in the determination of fenestration parameters, statistical analysis and ... arteriole and the portal venule [10] In average, the oxygen content of hepatic blood is rather low (~55 mmHg) However, oxygen gradients normally exist between the periportal and the perivenous areas of...

Ngày tải lên: 13/08/2014, 13:20

... comparative analysis between the architecture and function of the CHD and the structure and function of eukaryotic DNA, which we now define as the DNA hard drive (DHD) The computer ATA (Advanced ... correlations and expansions to these properties by structural and informational aspects of the of DHD, 3) examination of the current discrepancies between the CHD and the DHD, and how these discrepancies ... between the orthogonality of magnetic representation of data on the CHD to the orthogonal representation of information in the form of Qbits on the DHD The generation of various types of RNA from the...

Ngày tải lên: 13/08/2014, 16:20

... in the ubiquinone biosynthesis pathway The objective of this study is to understand the structure and function of these two MTases through the following experimental approaches1 To clone the ... nervous system, the head, the neck, the chest, the abdomen, the pelvis, the skin, and the soft tissues) get infected by Bacteriodes, they can cause or exacerbate abscesses and other infections ... determine the Apo and complex structures of these proteins with ligands (AdoMet/SAM and AdoHcy/SAH) using X-ray crystallography Structure function analysis to understand the role of these enzymes...

Ngày tải lên: 10/09/2015, 08:38

... this area and gases from vehicles on Le Duan road HUMAN IMPACTS - CONSEQUENCES SOLUTIONS  Increasing the number of wastebasket  Planning the rubbish dumps and quick transporting the waste as ... penalties) for the restaurant and visitors to keep the park green, clean and beautiful CONCLUSIONS  Plant species on peninsula are quite diverse  People are having huge impacts on the formation and development ... Location Biotics and abiotics Energy and material flow Human impacts, consequences and solutions Conclusion LOCATION  Thong Nhat Park  Peninsula : 1200 m2  Including : mainland, lake, plants,...

Ngày tải lên: 28/05/2016, 09:28

Ngày tải lên: 12/12/2013, 00:15

... Hence, the maintenance of a condensed chromatin structure throughout the entire body of a gene may rely on the combined actions of Set3 at the 5¢ end and Set2 at the 3¢ end In yeast the cycle of ... cycle of transcription commences with the recruitment of transcription factors and co-factors bound at the promoter, which modify the local chromatin structure and enable the assembly of the pre-initiation ... bp intervals The lighter colour shades depict the bottom half of the nucleosome, and the exploded view below the octamer depicts the arrangement of the histones contacting 73 bp of DNA within...

Ngày tải lên: 14/02/2014, 18:20

... functions, and topological features retain functionality and phylogeny However, the nature of the connections between these factors needs to be understood at the level of the protein domain The ... compares the studied network with randomized versions of it with the same size and degree distribution The so-called Z-score quantifies the difference between the studied network and an ensemble of randomized ... relation to the function and structure of TFs from available information From a structural point of view, the overabundance of self-interactions is associated with a majority group of 55% of basic...

Ngày tải lên: 19/02/2014, 07:20

... of the mature enzyme and by the ÔflapÕ The anchorage of the prosegment and of part of the N-terminus in the active site cleft is made by ionic interactions established between Lys11/Tyr13 of the ... other by three disulfide bridges A unique feature of the PSI is the swap of the N- and C-terminal portions of the saposin-like domain, where the C-terminal portion of one saposin is linked to the ... representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain, blue; C-terminal domain, red) (C) Model structure of the PSI domain of cardosin A based on the crystal structure...

Ngày tải lên: 19/02/2014, 12:20