structure and content of clinical study reports guideline step 4 1995

... 195 61 ( 14) 32 (13) 29 (15) Identifying and locating CPGs 310 (71) 191 (80) 119 (61) Critical appraisal of CPGs 222 (51) 130 ( 54) 92 (47 ) Content of specific CPGs 329 (76) 185 (77) 144 ( 74) Dealing ... (28) Time constraints on residents 2 14 (49 ) 118 (49 ) 96 (49 ) Time constraints on faculty 245 (56) 140 (59) 105 ( 54) None 94 (22) 35 (8.0) 53 (22) 22 (9.2) 41 (21) 13 (6.7) Barriers *Audit can ... (28.5) 22.0 (8.1) 53.8 ( 34. 0) 75% 94 (22) 31 (13) 63 (32) Gender of program director, n (%)...

Ngày tải lên: 11/08/2014, 05:21

... 195 61 ( 14) 32 (13) 29 (15) Identifying and locating CPGs 310 (71) 191 (80) 119 (61) Critical appraisal of CPGs 222 (51) 130 ( 54) 92 (47 ) Content of specific CPGs 329 (76) 185 (77) 144 ( 74) Dealing ... (28) Time constraints on residents 2 14 (49 ) 118 (49 ) 96 (49 ) Time constraints on faculty 245 (56) 140 (59) 105 ( 54) None 94 (22) 35 (8.0) 53 (22) 22 (9.2) 41 (21) 13 (6.7) Barriers *Audit can ... (28.5) 22.0 (8.1) 53.8 ( 34. 0) 75% 94 (22) 31 (13) 63 (32) Gender of program director, n (%)...

Ngày tải lên: 11/08/2014, 16:20

... aS1- and b-casein may contain » 20% a helix and possibly a small amount of b sheet [45 ,46 ] A conventional Raman study indicated » 10% a helical structure and » 20% b structure in both aS1- and ... b- and c-synuclein and cannot cross-seed its homologs J Biol Chem 275, 345 74 345 79 13 Cleveland, D.W., Hwo, S.H & Kirschner, M.W (1977) Physical and chemical properties of puri®ed tau factor and ... longer-chain (and nonglobular) versions of the structure of the Bowman±Birk inhibitor in Fig The X-ray crystal structure pi2 reveals that the /,w angles of most of the residues of the Bowman±Birk...

Ngày tải lên: 21/02/2014, 15:20

... produced and diffused in the period of study (January 19 94- December 20 04) and could be freely accessed The exclusion criteria were: 1) guidelines targeted to patients (patients'guidelines) and/ or ... 42 % [29%] 44 % [38%] 0 ,40 6% [17%] 11% [17%] 0, 24 0% [0%] 0% [0%] 0 ,43 42 % [44 %] 28% [31%] 39% [32%] 39% [50%] 0,12 13% [15%] 8% [13%] 13% [17%] 21% [13%] 0,01 11% [13%] 12% [12%] 7% [ 14% ] 12% [17%] ... Average of raters ICC (95% CI) Cronbach alpha 0,33 (0, 24 0 ,42 ) 0,09 (0,05–0,16) 0,09 (0,05–0, 14) 0,26 (0,19–0, 34) 0,16 (0,09–0, 24) 0,05 (-0,02–0,16) 0, 74 (0,65–0,81) 0 ,46 (0,28–0,61) 0,58 (0 ,45 –0,70)...

Ngày tải lên: 11/08/2014, 16:21

... = 1 04. 61 C2 No of molecules in the A.U 2 2 4 2.20 2.26 2.21 2.22 2.17 2.20 Solvent content (%) 44 .1 45 .5 44 .3 44 .6 43 .4 44. 0 Resolution range (Å) * 50.0 – 2.8 (2.9-2.8) 50.0 - 2 .4 (2 .49 -2 .4) 50.0 ... Materials and Methods 4. 2.1 Cloning, expression and protein purification 4. 2.2 Crystallization and structure determination 4. 2.3 Isothermal titration calorimetry 4. 2 .4 PDB Code 4. 3 Results and discussion ... 13019 20 044 22 841 11578 50893 36997 Redundancy 8.3(3 .4) 3.2(2 .4) 3.6(2.6) 5.6 (2.7) 5.1 (4. 4) 7.5 (5.3) Completeness (%) Overall (I/ σ (I) 95.3 ( 74. 7) 94. 7 (73.1) 93.5(86.0) 92.8 ( 74. 5) 94. 7 (68.0)...

Ngày tải lên: 10/09/2015, 08:38

... students per year Total Long-term 52,9 84 47,198 57,779 48 ,885 55,227 39,220 53, 245 37,763 51,1 94 41 ,41 1 54, 682 40 ,538 49 ,47 4 37,575 46 ,41 7 33,579 66,685 44 ,43 5 69,057 48 ,938 Total student Total Long-term ... schools Number of students Number of graduates Number of vocational training centers Number of people studying 52,115 45 ,737 45 ,320 45 ,600 198 43 ,44 6 182 29,987 177 1 54, 667 66,925 142 ,49 2 51,300 ... 92-93 266 37 93- 94 272 35 94- 95 259 35 95-96 253 37 (Source: Compiled by the author) Agr/Fors & fish 44 41 41 42 42 31 42 35 31 30 66 58 58 53 53 57 54 62 54 51 25 24 24 26 26 24 28 32 31 33 In...

Ngày tải lên: 13/04/2013, 10:31

... determination of the basic long-term goals and objectives of an enterprises, and the adoption of courses of action and the allocation of resources necessary for carrying out these goals” (Chandler,1989) ... number of buyers and their relative sizes • The prevalence of backward and forward integration • Ease of entry and exit • The pace of technological change in both production processes and new ... service more professional, and they structured Ministries into more logical groups by, for example combining the ministries of Light and Heavy industry, and the Ministries of Forestry and Agriculture...

Ngày tải lên: 13/04/2013, 10:32

... 1 142 0 212 542 .756 363,880 12, 345 20,600 6,158 1,256.361 558,651 26,368 45 543 145 24 2,516.57 855,329 21 ,41 2 56,983 6 ,42 5 3,397. 64 Table 4. 1 1995 Average growth rate (%) 1,225,319 56.05 25,831 48 .73 ... 1993 and 19 94 With a current ratio of 4. 03 times in 19 94, BPC could liquidity current assets at only 24. 81% (1 /4. 03) of book value and still pay off current liabilities in full Even in case of ... market 4. 5 Sales and Net income Sales and net income of BPC in the period 1991 -1995 are depicted in Figures 4. 5 and 4. 6 From 1991 up to now, the company’s sales have soared Sales in 19 94 was multiplied...

Ngày tải lên: 13/04/2013, 10:32

Ngày tải lên: 12/12/2013, 00:15

... 138 139 140 141 142 143 144 145 146 147 148 149 150 regulatory phase of gene transcription Mol Cell 18, 723–7 34 Avvakumov N & Cote J (2007) The MYST family of histone acetyltransferases and their ... sensitivity of the nontranscribed sequences flanking the 5¢ and 3¢ ends of the ovomucoid gene and the ovalbumin and its related X and Y genes in hen oviduct nuclei Biochemistry 19, 44 03 44 41 Wood ... nucleosome assembly A B Gal4 USF 20 Factor B cannot bind alone Factor A alone can bind USF Gal4 18 43 NF- kB USF 20 Factor A promotes binding of factor B 44 44 Gal4 NF-kB 20 46 Fig Transcription factors...

Ngày tải lên: 14/02/2014, 18:20

... interaction between v-KIND and MAP2, we generated EGFP-tagged KIND2 mutants with an Ala substitution at Leu461, 47 4, 47 7, 48 2 or 48 5 (L461A, L474A, L477A, L482A or L485A) and conducted a pull-down ... CD2-1-6-2 of MAP2 (Fig 6B) KIND2 L461A, L474A and L477A mutants failed to bind to CD2-1-62 of MAP2, whereas the L482A and L485A mutants did bind to this module These results suggest that the Leu461, 47 4 ... v-KIND and PTPN13 shared 46 .9% homology and had only two or three conserved Leu residues out of seven residues It is notable that four Leu residues (amino acids 46 1, 47 4, 47 7 and 48 2) and one...

Ngày tải lên: 14/02/2014, 19:20

... different levels of biological organization: from the life histories of individuals, to the structure and dynamics of populations and communities, to the fluxes and pools of energy and materials ... & Paranjape, M A (1977) Structure of pelagic food-chain and relationship between plankton and fish production Journal of the Fisheries Research Board of Canada, 34, 2 344 –2353 Sprules, W G & Bowerman, ... Sciences, 24, 140 1– 140 8 BODY SIZE AND SUSPENSION FEEDING Nowell, A R M & Church, M (1979) Turbulent flow in a depth-limited boundary layer Journal of Geophysical Research, 84, 48 16 48 24 Nowell,...

Ngày tải lên: 17/02/2014, 19:20

... representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain, blue; C-terminal domain, red) (C) Model structure of the PSI domain of cardosin A based on the crystal structure ... Physiol 131, 43 0 44 2 84 Lindholm, P., Kuittinen, T., Sorri, O., Guo, D.Y., Merits, A., Tormakangas, K & Runeberg-Roos, P (2000) Glycosylation of phytepsin and expression of dad1, dad2 and ost1 during ... prosegment and total or partial removal of the internal Ó FEBS 20 04 Plant aspartic proteinases (Eur J Biochem 271) 2069 Fig Ribbon representation of the crystal structures of cardosin A (A) and prophytepsin...

Ngày tải lên: 19/02/2014, 12:20

... ca7L 247 T acts as an agonist [59] a3b2 99 [55] a7 252 [55] ca7 349 [59] ca7L 247 T 1 94 [59] a3b2 9.6 [55] a7 44 1 [35] a7 220 [ 34] , 100 [23], 191 [35], 1 040 [106] ha7 132 [85] a9 1800 [ 34] a3b4 no ... 518 [39] a7 4. 5 [80] a3b2 3.1 [80] a4b2 152 [80] ha3b2 1.1 [38] ha3b4 755 [38] ha4b2 309 [38] a3b4 27.500 [61] a3b4 750 [41 ], 966 [61], Kdd 500 [41 ] a7 10 000 [41 ] a3b2 Kdd 1.9 [ 64] IC50 (nM) ... [39], Kdd 0.35 [ 64] a6/a3b2b3 0 .4 [39] ha6/a4b4 (HEK293) 24 [1 04] a7  100 [37] a4b2 43 0 [39] a7 30 [61] ca7/5HT3 (HEK293) 103 [61] a7 61 [55] a3b2 1970 [55] a7 1710 [55] a3b2 241 [55] a7 13 [55]...

Ngày tải lên: 19/02/2014, 12:20

... [31,32,36] and their threedimensional structures were determined [ 34, 37 40 ] In subsequent sections, we describe the structure and dynamics of each protein, and present a comparison of sbwAFP and TmAFP ... residues Gly 34 to Thr49) and TmAFP (blue, residues Asn29fiGly41) Letters denote the five residues of one of the three sides of sbwAFP or six residues of one of two sides of TmAFP The strands that make ... the structure and PDB code shown below each panel (A) Overlap of isoform 337 with the structure of the longer isoform CfAFP-501 using the main chain of residues Thr23fiAsn90 in isoform 337 and...

Ngày tải lên: 19/02/2014, 16:20

... 53.0 53.1 49 .5 54. 4 44 .6 48 .1 42 .1 43 .3 51.0 46 .0 44 .9 45 .3 38.9 Similar to the Onychophora and Chelicerata, a-helix 1.2 is missing in the myriapod hemocyanins Tentative 3D structures of the subunits ... ScoHcD ScoHcX SpiHc1 AJ 344 359 AJ512793 AJ431379 AJ 344 360 AJ431378 AJ297738 2258 2283 2236 2271 2209 2082 656 659 673 668 685 653 74. 44 73.93 75.91 74. 75 77. 74 73. 74 5 .44 5.57 5.68 6.18 5.79 6.16 ... K.H & Hol, W.G.J (1993) Crystal structure of Centipede hemocyanin structure (Eur J Biochem 270) 2867 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 deoxygenated Limulus polyphemus...

Ngày tải lên: 20/02/2014, 11:20

... the study of problem solving action and report: I) the collected of data on problem solving and talk about problem solving, 2) development of a process model of these behaviors, and 3) use of ... problem solving from a record of the problem solving report and a record of moves made Then, we use this extracted trace to evaluate our model of the role of point of view in problem solving SUMMARY ... organization of the problem ("point of view"), and systematic multl-utterance structures used to express the forms of inference used to solve the problem ("Justificatlon argument structures")...

Ngày tải lên: 21/02/2014, 20:20

... radius of gyration is given by: R2 ¼ fM R2 þ fD R2 g gM gD ð7Þ where fM and fD are the mass fractions of monomer and dimer, respectively, and RgM and RgD are the radii of gyration for the monomer and ... asymmetric unit of both crystal structures [9,10] has a radius of gyration of almost 4. 3 nm, and would have a forward scattering approximately twice as large as that observed by us Neither of these ... that it can be viewed as a dimer of dimers The tetramer may be composed of either AB and CD dimers, or AD and CB dimers The AB dimer has a radius of gyration of 4. 0 nm, but has an extremely limited...

Ngày tải lên: 22/02/2014, 07:20

... were 0.6, 8.6, 24. 7, 48 .8, 96.9, 193.2, 345 .7, 49 8.2, 795.2, 1196 .4 and 1597.3 ms, and those for the R2 experiments were 0, 8.6, 17.2, 25.8, 34. 4, 43 .0, 51.7, 60.3, 77.5 and 94. 7 ms The excitation ... NMR structure and function of the eRF1 C-domain A B C E D Fig The solution structure of the C-domain (A) Stereo view of the ensemble of the final 48 calculated structures Twenty-four structures of ... fit of the heavy atoms (Ca, C, and N) from three b-strands and the a-helices of both the closed and the open conformer onto a corresponding set of atoms of ˚ Ynr 046 w gives rmsd values of 3.7 and...

Ngày tải lên: 06/03/2014, 11:20

... typhimurium [ 34] S aureus [35] S aureus [27,35] Residue Thr385 Pro4 04 Pro406 Val407 Ala426 Leu430 Asp4 34 Pro435 Thr436 His438a Gln 447 Gly451a Gly452 Table (Continued) FEBS Journal 277 (2010) 3789–3803 ª ... III–V The mutations T385N, P404L, P404Q, P404R, P406L, V407F and H438N can affect the conformational dynamics of EF-G through their effect on the structure and dynamics of the linker, but can also ... a new amino group to the drug Similarly, Glu433 in helix AIII hydrogen bonds with Arg4 64 in helix BIII, and the mutations R464C, R464H, R464L and R464S will cause changes to the packing between...

Ngày tải lên: 06/03/2014, 22:21