structural description and apparent physiological role of sp b

... that the longest and < /b> intermediate bands were full-length CCN4 ⁄ WISP1 and < /b> WISP1v, respectively However, the shortest band was a novel variant of < /b> WISP1 (WISP1vx) not previously described (Fig 2A) ... comparable results CCN4 ⁄ WISP1 and < /b> WISP1v proteins were actually translated from CCN4 ⁄ WISP1 and < /b> WISP1v mRNAs in HCS-2 ⁄ cells A rabbit ortholog of < /b> the reported CCN4/WISP1splicing variant (WISP1v) ... cells (right) that had been cultured weeks at confluence was analyzed The expected sizes of < /b> the amplicons were 550 bp from rabbit CCN4 ⁄ WISP1 and < /b> 289 bp from rabbit WISP1v, respectively, which were...

Ngày tải lên: 07/03/2014, 10:20

... hormone binding globulin (SHBG) to which most circulating testosterone is bound (and < /b> thus is not ‘free’) SHBG is produced by the liver and < /b> is regulated by sex hormones and < /b> especially by insulin, and < /b> ... PCB exposure This conclusion would fit with the absence of < /b> any effect at puberty in a larger study of < /b> boys from the Faroe islands who exhibited a wide range of < /b> exposure to PCBs, based on cord blood ... acting, feasible based on animal studies o Dissimilarly acting, no animal data • The mechanism needs to be measurable, but probably not possible because of < /b> access and < /b> ethical issues • Problems in...

Ngày tải lên: 13/02/2014, 10:20

... Protein purification, and < /b> cloning and < /b> characterization of < /b> the cDNA and < /b> gene for xylose isomerase of < /b> barley Eur J Biochem 237, 240–246 15 Vangrysperre W, Vandamme J, Vandekerckhove J, Debruyne CK, Cornelis ... effect of < /b> mutations of < /b> His-220 on enzyme stability J Biol Chem 269, 2687–2694 Cha J (1999) Contribution of < /b> second metal binding site for metal specificity of < /b> d-xylose isomerase J Microbiol Biotechnol ... Fuxreiter M, Bocskei Z, Szeibert A, Szabo E, Dallmann G, Naray-Szabo G & Asboth B (1997) Role < /b> of < /b> electrostatics at the catalytic metal binding site in xylose isomerase action: Ca2+ inhibition and < /b> metal...

Ngày tải lên: 23/03/2014, 13:20

... espL2, nleB1 and < /b> nleE on SpLE3) or by Ler with Pch (e.g espJ and < /b> tccP on Sp1< /b> 4) All the genes in the Pch–Ler regulon are repressed by H-NS, but once expression of < /b> pchA and < /b> ler is stimulated by ... starvation butyrate etc Regulation and < /b> distribution of < /b> the espL gene family in EHEC ⁄ EPEC Orthologs of < /b> the EHEC O157:H7 Sakai espL2 gene have been found in all EHEC and < /b> EPEC strains examined by hybridization ... downstream of < /b> the espL2 gene in these strains (NCBI database) EspL2 must be an essential type III effector for the pathogenicity of < /b> EHEC and < /b> EPEC In addition, because the nucleotide sequences of < /b> espL2...

Ngày tải lên: 29/03/2014, 09:20

... issues like the determinants behind a disclosure choice, the characteristics of < /b> the discloser (i.e credibility) and < /b> of < /b> the information disclosed (i.e verifiability) and < /b> how these characteristics ... weaknesses of < /b> the research design, the main assumptions made and < /b> the main results are presented Finally and < /b> most importantly, the contribution of < /b> the paper to the literature needs to be discussed and < /b> ... evidence from the practice about the relevance of < /b> the findings The presenter should also be prepared to respond to questions about the paper made by other students Specifically each student is...

Ngày tải lên: 29/03/2014, 14:20

... relation to body mass index and < /b> obesity, the ApoE4 phenotype also appears to be the link between obesity and < /b> abnormalities related to glucose metabolism and < /b> diabetes In obese men, the expression of < /b> the ... [36,37] Despite the pivotal role < /b> of < /b> obesity and < /b> dyslipidemia in the development of < /b> the metabolic syndrome and < /b> heart disease, the functional interactions between adipose tissue and < /b> the lipid and < /b> lipoprotein ... imbalance and < /b> genetic predisposition may also contribute to obesity [24–35] Epidemiological and < /b> population studies have established a direct correlation between obesity and < /b> the development of...

Ngày tải lên: 29/03/2014, 22:21

... Division of < /b> Primary Care and < /b> Public Health, University of < /b> Oxford, UK 5Universitat Autònoma de Barcelona (UAB), Barcelona, Spain Universitat Pompeu Fabra (UPF), Barcelona, Spain Authors’ contributions ... Physical well-being Boys Girls Boys Girls Psychological well-being School Parent Environment relation and < /b> Home Life Boys Boys Girls Boys Girls Boys Girls 55.2 Girls Social Support and < /b> Peers Low: ... events KS-10 Boys Physical well-being Psychological wellbeing Girls School Environment Girls Parent relation and < /b> Home Life Social Support and < /b> Peers Girls Boys Boys Girls Boys Boys Girls Boys Girls...

Ngày tải lên: 20/06/2014, 16:20

... projects handle more than twice the expected number of < /b> clients At the end of < /b> 2007, 3600 PWID had been reached by NSPs [58] A target has been set of < /b> reaching 20,000 PWID by 2010 [58] MMT has been scaled ... country's initiatives by supporting the conduct of < /b> a situation and < /b> response analysis of < /b> PWID-related work in the country and < /b> of < /b> IHBSS among PWID in the cities of < /b> Zamboanga and < /b> General Santos [65] ... the status of < /b> a considered land-locked country and < /b> being fast transformed in a land linked country [46] A high way being developed by the Asian Development Bank and < /b> the Great Mekong SubRegion Governments...

Ngày tải lên: 11/08/2014, 18:20

... was abated by blocking the activity of < /b> interleukin-1, and < /b> interleukin-1β mRNA and < /b> protein levels are increased by interleukin-5 Interleukin-5 may contribute to airway hyperreactivity by both ... placebo Patients were challenged with allergen weeks before and < /b> and weeks after dosing Peripheral blood and < /b> sputum eosinophil levels were measured, and < /b> early-phase and < /b> late-phase asthmatic responses ... eosinophils and < /b> basophils possess a type-1 cytokine receptor for interleukin-5 with a specific α-subunit and < /b> the βc-subunit that confers high-affinity binding and < /b> signal transduction A specific inhibitor...

Ngày tải lên: 12/08/2014, 18:20

... flash of < /b> skin above the waist of < /b> her jeans, and < /b> the way her breasts – Jesus, is she even wearing a bra? Christ, Caid, stop looking at her breasts! – strained against the fabric of < /b> her shirt “obyn Shit, ... laughed, startled by a less serious side of < /b> obyn that I hadn’t seen before e laugh was spontaneous, and < /b> seemed to take us both by surprise, probably because my laughter in her presence up until ... Liz and < /b> me e rest of < /b> the regulars sat across from us; Danny De Lorenzo, a loud but undeniably likable Italian ladies man, Henry Stoddard, stocky and < /b> strong with a bald head and < /b> bushy mustache, and...

Ngày tải lên: 02/06/2015, 21:24

... of < /b> the junctions The size of < /b> J(V) data sets is determined by the number of < /b> junctions and < /b> the number of < /b> scans of < /b> each junction The number of < /b> junctions reflects the reproducibility and < /b> the number ... rectification ratio of < /b> diodes and < /b> the on-off ratio of < /b> switches In a varying degree of < /b> rigor, the reproducibility, in terms of < /b> precision (widths of < /b> data distributions) and < /b> replicability (within a laboratory ... 最后谨以此文献给我挚爱的家人。 iv Table of < /b> Contents Thesis Declaration i Acknowledgement iii Table of < /b> Contents v Summary x List of < /b> Table xiii List of < /b> Figures xv List of < /b> Abbreviations xxviii List of < /b> Symbols xxix Chapter...

Ngày tải lên: 09/09/2015, 08:18

... be submitted II CONTENTS ACKNOWLEDGEMENT I LIST OF < /b> PUBLICATIONS II ABSTRACT IX LIST OF < /b> TABLES XIII LIST OF < /b> FIGURES XIV LIST OF < /b> ABBRIVIATIONS XV 1 INTRODUCTION 1.1 Obstructive airway disease and < /b> ... contribution of < /b> stressful life events and < /b> perceived stress in the psychiatric comorbidity and < /b> quality of < /b> life of < /b> asthma and < /b> COPD in adolescent, adult and < /b> elderly individuals, as well as the role < /b> of < /b> ... Correlations of < /b> psychological and < /b> biological stress variables with IL-4 level 82 Table 17 Independent associations and < /b> mediational analyses of < /b> measures of < /b> perceived and < /b> HPA stress and < /b> NPY with...

Ngày tải lên: 09/09/2015, 11:28

... accounted for 36% of < /b> abortions, 30% of < /b> abortions were obtained by non-Hispanic Black women, 25% of < /b> abortions were obtained by Hispanic women and < /b> 9% by women of < /b> other races Hispanic women represent ... abortions, 30% of < /b> abortions were obtained by nonLatina Black women, 25% of < /b> abortions were obtained by Latina women and < /b> 9% by women of < /b> other races From 1997-2006, the rate of < /b> abortion in non-Latinas ... number of < /b> pregnancies 42 Table describes the mean and < /b> standard deviation for level of < /b> familism and < /b> number of < /b> pregnancies Table Descriptives Mean and < /b> standard deviation for level of < /b> familism and...

Ngày tải lên: 01/10/2015, 17:30

... List of < /b> Tables Table Bank loans and < /b> Party leadership positions of < /b> general managers 40 Table Summary statistics of < /b> main variables 41 Table Pearson correlation coefficients between bank ... measure of < /b> access to bank credit is Numbank, which is a category variable of < /b> the number of < /b> banks that the firm business with The bigger the number, the more likely the firm has access to bank channeled ... common and < /b> value-reduced Next, I use a less direct measure of < /b> access to bank credit-the number of < /b> banks that the firm business with Ideally, more banks suggest a higher possibility of < /b> obtaining bank...

Ngày tải lên: 16/10/2015, 15:36

... LIST OF< /b> ABBREVIATIONS   ADS albumin-dextrose-saline AFB acid-fast bacillus/bacilli AIDS Acquired immune deficiency syndrome BCG Bacille Calmette-Guerin bp base pairs BSA Bovine serum albumin BSC Biosafety ... of < /b> 16S rRNA and < /b> IS6110 sequences specific to MTB forms the basis of < /b> one of < /b> the procedures (Boshoff and < /b> Barry, 2005) Clinical diagnostics of < /b> TB employs the use of < /b> chest X-rays to check for tubercles ... pYUB854 Plasmids M tuberculosis H37Rv H37Rv ∆fbiC fbiC -complemented BCG Invitrogen mutant M bovis BCG strain incapable of < /b> expressing fbiC and < /b> biosynthesising cofactor F420 mutant M bovis BCG...

Ngày tải lên: 16/10/2015, 15:38

... traditional robots, for example In particular, it is designed to overcome two of < /b> the major barriers to the adoption of < /b> industrial robots: usability and < /b> cost Instead of < /b> hundreds of < /b> thousands of < /b> dollars, ... “roboticists” He is the former Panasonic Professor of < /b> Robotics at the Massachusetts Institute of < /b> Technology (MIT) and < /b> previously founded iRobot, maker of < /b> the Roomba, one of < /b> the world’s first robot ... but humans have already been relieved of < /b> millions of < /b> equally torturous jobs thanks to industrial automation and < /b> robotics Although there has been concern about the loss of < /b> jobs ever since the Industrial...

Ngày tải lên: 04/12/2015, 00:21

... variables, PR1LIB, PR2LIB and < /b> DLTPR1 DLTPR2 These are interaction terms between LIB and < /b> DLTALIB, on the one hand, and < /b> PRIN1 and < /b> PRIN2 on the other Finally, to look at how the impact of < /b> PRIN1 and < /b> ... important, both for performance and < /b> the speed of < /b> economic liberalization; also that political reform, in particular, affects the speed of < /b> economic liberalization Belarus and < /b> Uzbekistan offer examples of < /b> ... dimensions of < /b> the transition process See Aslund, Boone and < /b> Johnson (1996), de Melo, Denizer and < /b> Gelb (1996a and < /b> b) , de Melo and < /b> Gelb (1996), Fisher, Sahay and < /b> Vegh (1996a ,b) , Sachs (1996a), Selowski and...

Ngày tải lên: 30/08/2016, 07:40

... generated that spans the possible combinations of < /b> charge neutralization (by mutation to alanine) and < /b> charge inversion (by mutation to lysine and < /b> aspartate, respectively) at positions D72 and < /b> K8 After ... (for the double mutants of < /b> D72K ⁄ K8D and < /b> D72K ⁄ K8A) or even abolished (for the double FEBS Journal 272 (2005) 3317–3327 ª 2005 FEBS Table Double-mutant cycle analysis Interaction Gibbs energies ... Interestingly, one of < /b> the side chain oxygens of < /b> D72 appears to be hydrogen-bonded to the backbone N atom of < /b> G6, bridging the crossing between the N- and < /b> C-terminal a helices of < /b> cyt c6 (Fig 6)...

Ngày tải lên: 30/03/2014, 20:20

... with N10 and < /b> E97 of < /b> the second subunit The backbone NH group of < /b> R98 forms a hydrogen bond with the backbone CO of < /b> F102 Furthermore, the orientation of < /b> the side chain of < /b> the two residues brings ... FEBS M Banerjee et al Effect of < /b> mutation on the dimer interface of < /b> PfTIM DHAP Fig Key backbone hydrogen bonds between K12 and < /b> the side chains of < /b> N10 and < /b> Q64, which maintain the unusual Ramachandran ... (A) 4.02 NE2 Arg-99 (A) through its backbone CO and < /b> NH groups to Arg98 and < /b> Glu97 of < /b> the neighboring subunit The dimer interface and < /b> the network of < /b> hydrogen bond interactions positioning the active...

Ngày tải lên: 18/02/2014, 11:20

... cyt b6 f complex and < /b> phosphorylates the mobile LHCII antenna (dark green; P, phosphate groups) The activity of < /b> LHCII kinase is regulated by co-operative redox control, both via PQ and < /b> cyt b6 f, and < /b> ... light (see the two hm bolts above PSII), when the PQ pool becomes over-reduced Binding of < /b> the PQH2 to the quinol-binding site of < /b> the cyt b6 f complex activates a specific thylakoidbound kinase that ... the stroma Phospho-LHCII, together with the phosphorylated linker subunit CP29 (and < /b> possibly TSP9 in plants) (blue triangles), detaches from PSII and < /b> docks onto PSI to redirect absorbed excitation...

Ngày tải lên: 16/03/2014, 06:20