steps in excitation contraction coupling in skeletal muscle figures 1 12 and 1 13

Báo cáo khoa học: Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma pot

Ngày tải lên : 07/03/2014, 06:20

... 1. 2 1. 5 0.9 0.6 26 80 90 52.4 ± 1. 0 13 .3 ± 2 .1 9.6 ± 0.4 2.2 82 .1 88.5 NMb 11 2 12 0 11 9 12 5 Reduction (%)c ST ± ± ± ± 4.0 3.2 1. 2 1. 5 10 2.4 ± 2.6 ND 11 4.5 ± 2.9 96 41 33 12 ± ± ± ± 3.0 2 .1 6.7 ... 4.7 2.9 4.9 12 5 .1 ± 3.0 14 2.6 ± 1. 2 16 4.5 ± 3.4 12 6.7 44.8 14 .9 0.9 ± ± ± ± 2.9 3.5 3.9 1. 1 8.3 32.0 89.9 99.4 12 0.9 ± 3.7 10 .9 ± 1. 9 0.6 ± 0.8 3.3 92.3 99.0 a CK content was measured in contralateral ... creatine and creatine kinase in sarcoma of creatine and an increased choline ⁄ creatine ratio, and a decrease in the activity of CK and some of its isoforms in several different forms of cancer [15 –20]...

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Báo cáo khoa học: A new pathway encompassing calpain 3 and its newly identiﬁed substrate cardiac ankyrin repeat protein is involved in the regulation of the nuclear factor-jB pathway in skeletal muscle pdf

Ngày tải lên : 29/03/2014, 21:20

... heart and skeletal muscle [18 ,22,23], Ankrd2 is mainly expressed in skeletal muscle [18 ,24,25], CARP in the heart [18 , 21, 26–28] and DARP in equivalent amounts in both tissues [20] Interestingly, ... Komulainen J, Kainulainen H & Kyrolainen H (2009) Effects of fatiguing jumping exercise on mRNA expression of titin-complex proteins and calpains J Appl Physiol 10 6, 14 19 14 24 31 Aihara Y, Kurabayashi ... more efﬁciently bound to titin after cleavage by calpain (P < 0. 01; Fig 2E) It is worth noting that, in skeletal muscle, an endogenous inhibitor maintains calpain in an inactive state until a signal,...

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Báo cáo y học: " Module-based multiscale simulation of angiogenesis in skeletal muscle" doc

Ngày tải lên : 13/08/2014, 16:20

... governing equations for VEGF164 and VEGF120 are: ∂CV164 = DV164 ∇ CV164 + ∂t koff ,V164,H CV164•H − kon,V164,H CV164 CH (6) ∂CV120 = DV120 ∇ CV120 ∂t (7) where CV164, CV120 , CH and CV164•H are ... for arteriolar inlets 0.6,0.3 - Oxygen DV120 V120 diffusivity in ECM 1. 13 × 10 -6 cm2 s -1 VEGF DV164 HECM V164 diffusivity in ECM HSPG density in ECM 1. 04 × 10 -6 7.5 × 10 -10 cm2 s -1 pmol μm-3 ECM ... by tissue 1. 5 × 10 -3, 1. 67 × 10 -4 ml O2 ml -1 s -1 Oxygen Mb Cbind Myoglobin O2-binding capacity 1. 016 × 10 -2 ml O2 (ml tissue) -1 Oxygen CRBC bind P50,Mb P50,Hb nh Hemoglobin O2-binding capacity...

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Mitsugumin 53 (MG53) as an e3 ligase in skeletal muscle

Ngày tải lên : 20/05/2016, 15:30

... targeting insulin receptor substrate -1 Cell Death and Differentiation 17 (2 010 ), 12 54 -12 65 10 MG53 is highly expressed in skeletal muscle and heart MG53 is upregulated during myogenesis 11 Figure ... repair by interacting with dysferlin -1, caveolin-3 and cavin -1, forming membrane repair machinery after acute membrane damage in skeletal and cardiac muscles (Figure 3) (14 -18 ) Indeed, the muscle ... activated integrin state at the cell surface.The integrin-binding proteins paxillin and talin recruit focal adhesion kinase (FAK) and vinculin to focal contacts -Actinin is a cytoskeletal protein that...

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THE EFFECTS OF CHROMIUM ON SKELETAL MUSCLE MEMBRANE/CYTOSKELETAL PARAMETERS AND INSULIN SENSITIVITY

Ngày tải lên : 24/08/2014, 12:27

... of insulin resistance (11 6 -11 8) Systemic inflammation is known to result in macrophage accumulation in adipose tissue (11 9, 12 0) and more recently skeletal muscle (12 1), for example The expanding ... hyperinsulinemia is typically viewed as a compensatory response by the pancreas to offset insulin resistance, studies in man (12 8, 12 9) and in cultured cells (13 0, 13 1) have clearly shown that insulin ... relevant insulin concentrations [10 0-833 µU/ml; 600-5000 pM] (13 4) induces insulin resistance while proximal insulin signaling remains intact Similarly to hyperinsulinemia, exposure of muscle and...

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Báo cáo y học: "Skeletal muscle sodium glucose co-transporters in older adults with type 2 diabetes undergoing resistance training"

Ngày tải lên : 31/10/2012, 17:08

... utilization in skeletal muscle It has been proposed that insulin resistant individuals have a defect in GLUT4 trafficking and targeting leading to reduced GLUT4 in the cell membrane in skeletal muscle ... human insulin resistance J Clin Invest 19 98 ;10 1 (11 ):2377-86 32 Hayashi T, Wojtaszewski JF, Goodyear LJ Exercise regulation of glucose transport in skeletal muscle Am J Physiol 19 97;273(6 Pt 1) :E1039- 51 ... Hemoglobin (%) Fasting Blood Glucose (mg/dL) Resistance Training (N =13 ) 66 ± 9/4 32 .1 ± 6.8 8±6 8.6 ± 1. 8 Control (N=5) 60 ± 3/2 33.4 ± 6.3 10 ± 8 .1 ± 1. 2 P-value * 0 .17 0.63 0.28 0.99 0. 41 147 ±...

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Tài liệu Báo cáo khoa học: Subproteomics analysis of Ca2+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle pdf

Ngày tải lên : 19/02/2014, 16:20

... pH A 10 2D ‘Stains-All’ analysis of dystrophic muscle Normal Hot-CB 11 6 66 45 78 10 11 12 13 pH B 10 Hot-CB mdx 11 6 66 45 78 10 11 13 12 Fig Proteomics-based identiﬁcation of major protein species ... Ca2+-binding proteins, calsequestrin, calmodulin, troponin C, and S -10 0, with the cationic carbocyanine dye ÔStainsallÕ J Biol Chem 258, 11 267 11 273 33 Murray, B.E & Ohlendieck, K (19 97) Crosslinking ... Normal Stains-All B -DG SAR 95 C 10 66 Dp427 10 NKA CSQ D CAM SERCA1 11 pH B E 205 mdx 10 1- DHPR Stains-All F CSQ SAR 95 G 10 66 CAL CSQ CAM 11 Fig 2D ‘Stains-All’ labelling of normal and mdx muscle...

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Body composition in the elderly: Reference values and bioelectrical impedance spectroscopy to predict total body skeletal muscle mass pot

Ngày tải lên : 28/03/2014, 20:20

... 95 16 1 69.2 26.5 40.6 28.6 15 .6 40.7 11 .0 17 .4 6.6 679 16 00 5 .19 14 .1 16.5 0.87 15 1 51. 4 20.3 31. 1 15 .7 12 .1 28.4 6 .1 12. 4 5 .1 564 11 60 4.23 11 .2 12 .0 0.69 17 1 90.7 34.6 50.9 43.5 19 .5 50.7 16 .4 ... 18 5 10 6.6 33.2 71. 3 39.2 22.9 43.6 12 .4 31. 0 9.6 7 01 1750 6.66 24.2 29.9 1. 01 162 70.9 27.0 41. 7 29.2 15 .9 40.6 11 .1 18 .1 6.9 638 15 81 5.06 14 .8 16 .7 0.90 14 9 52.3 18 .8 31. 8 17 .1 11. 9 30.9 6 .1 13. 2 ... 16 .4 21. 7 7.9 803 214 7 6.23 16 .9 21. 4 1. 05 17 5 82 .1 26.9 55.8 26.3 18 .3 31. 7 8.6 26.3 8.6 574 13 08 5.54 19 .1 22.8 0.84 16 4 61. 8 21. 5 42.9 14 .0 4.2 19 .5 4.7 20.8 7.5 459 935 4.45 14 .6 16 .9 0.69 18 5...

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Báo cáo hóa học: " Overexpression of microRNA-206 in the skeletal muscle from myotonic dystrophy type 1 patients" docx

Ngày tải lên : 18/06/2014, 16:20

... DM1 muscle In this work we have profiled the expression of miR -13 3 (miR -13 3a, miR -13 3b), miR -1, miR -18 1 (miR -18 1a, miR181b, miR -18 1c) and miR-206, specifically induced during myogenesis, in muscle ... showing the Utrophin and α-Tubulin protein expression levels in DM1 patients and controls Utophin/Tubulin ratios in the analyzed samples are: DM1 -1 = 0,63, DM1-2 = 0,74, DM1-3 = 0, 31, DM1-4 = 1, 66, ... in skeletal muscles, and promotes muscle differentiation if induced by MyoD and myogenin during myogenesis [16 ,17 ] These muscle- specific miRNAs seem to participate in muscle diseases, including...

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báo cáo hóa học: " Influence of dietary state and insulin on myocardial, skeletal muscle and brain [18F]fluorodeoxyglucose kinetics in mice" pptx

Ngày tải lên : 21/06/2014, 02:20

... Muscle Brain Non-fasted 9.5 ± 2.4 0.55 ± 0 .11 1. 45 ± 0. 41 Non-fasted and insulin Fasted 9.98 ± 1. 06 3.48 ± 1. 73* 0.97 ± 0.29* 0.40 ± 0.09 0.96 ± 0 .11 * 2.87 ± 0.50* Fasted and insulin 9.35 ± 1. 62 ... insulin 20. 01 ± 12 .70 2.04 ± 1. 80* 3.56 ± 1. 21 MRgluc (mg/min /10 0 g) Non-fasted 19 . 41 ± 5.39 1. 06 ± 0.34 3. 21 ± 0.53 Fasted 3.26 ± 1. 97* 0.34 ± 0.08* 2.85 ± 0.23 SUV (45-60 p.i.) Ki (ml/min /10 0 ... during insulin clamping (about 4.9 mg/min /10 0 g) [20] In the myocardium, the MRgluc in mice (19 .4 and 3.3 mg/min /10 0 g in non-fasted and fasted mice, respectively) again were similar to those in...

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Báo cáo y học: " Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV-1 transgenic rats" docx

Ngày tải lên : 10/08/2014, 05:22

... Alcohol Clin Exp Res 2007, 31( 12) :19 53 -19 62 47 Vary TC, Frost RA, Lang CH: Acute alcohol intoxication increases atrogin -1 and MuRF1 mRNA without increasing proteolysis in skeletal muscle Am J ... LIF(-/-) mouse Cytokine 2006, 34(3-4) :12 5 -13 0 31 Kim H, Jo C, Jang BG, Oh U, Jo SA: Oncostatin M induces growth arrest of skeletal muscle cells in G1 phase by regulating cyclin D1 protein level Cell ... 89(4) :13 65 -13 79 doi :10 .11 86 /17 42-6405-8-30 Cite this article as: Clary et al.: Chronic alcohol ingestion exacerbates skeletal muscle myopathy in HIV -1 transgenic rats AIDS Research and Therapy 2 011 ...

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Báo cáo y học: "Insulin alleviates degradation of skeletal muscle protein by inhibiting the ubiquitin-proteasome system in septic rats" pps

Ngày tải lên : 11/08/2014, 06:23

... increased to 4.8 mU.kg -1. min -1, the net release of tyrosine was significantly decreased compared to the LPS and low-dose insulin groups (298. 21 ± 11 .18 vs 383.4 ± 12 .72, P < 0. 01; 298. 21 ± 11 .18 ... into four groups as follows: control group (n = 12 ) LPS group (n = 12 ), low-dose insulin group (n = 12 ) and high-dose insulin group (n = 12 ) The sepsis model was mimicked by intraperitoneal injection ... intraperitoneal injection with LPS, low -and high-dose insulin group animals received a continuous infusion of insulin at 2.4 mU.kg -1 min -1 or 4.8 mU.kg -1. min -1, and blood glucose was controlled to 4.4-6.1...

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Báo cáo y học: " No effect of short-term amino acid supplementation on variables related to skeletal muscle damage in 100 km ultra-runners - a randomized controlled trial" potx

Ngày tải lên : 11/08/2014, 23:21

... amino acids - Δ control) 16 8.3 ( 61. 7) 4,582.5 (3 ,15 0.3) 4, 414 (3 ,10 7) ** 15 7.8 (74.5) 3,8 61. 5 (2,357.8) 3,703 (2,340) ** 711 (1, 065) 6.2 (1. 4) 10 .6 (2 .1) 4.4 (1. 6) ** 5.9 (1. 5) 9.5 (1. 6) 3.6 (1. 5)** ... in running during training (km/h) 10 .9 (1. 8) 11 .2 (1. 1) Number of finished 10 0 km runs 5.7 (5 .1) (n = 10 ) 2.8 (2.3) (n = 8) Personal best time in a 10 0 km run (min) 6 01 (10 7) 672 (98) Results ... a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise Journal of Science and Medicine in Sport 2 010 , 13 :17 8 -18 1 doi :10 .11 86 /15 50-2783-8-6...

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Báo cáo y học: " A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease" pot

Ngày tải lên : 12/08/2014, 15:20

... 40.5 (17 .9) 39.8 (19 .9) 18 1 (32) 5.2 (1. 1) 9.4 (1. 4) 34.8 (1. 5) 66.3 (17 .9) 24.3 (5.2) 70.5 (15 .7) 47.5 (8.3) 67.4 (19 .5) 98.9 (43.9) 62.0 (9.4) 36.0 (18 .4) 40 .1 (19 .3) 17 6 ( 41) 5.2 (0.9) 9.4 (1. 6) ... 2007, 62 :11 5 -12 0 Decramer M, Lacquet LM, Fagard R, Rogiers P: Corticosteroids contribute to muscle weakness in chronic airflow obstruction Am J Respir Crit Care Med 19 94, 15 0 (1) :11 -16 Hopkinson ... MA, Evans WJ, Roubenoff R: Aging of skeletal muscle: a 12 -yr longitudinal study J Appl Physiol 2000, 88(4) :13 21- 132 6 Ferrucci L, Penninx BWJH, Volpato S, Harris TB, Bandeen-Roche K, Balfour J,...

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Báo cáo y học: " Skeletal muscle dysfunction in chronic obstructive pulmonary disease" pps

Ngày tải lên : 12/08/2014, 18:20

... Research Vol No Mador and Bozkanat References 10 11 12 13 14 15 16 17 18 19 20 Bernard S, LeBlanc P, Whittom F, Carrier G, Jobin J, Belleau R, Maltais F: Peripheral muscle weakness in patients with ... changes include an increase in mitochondrial number, increased muscle capillarization, and an increase in muscle oxidative enzyme activity After intense training the proportion of type I fibers increases, ... physical training and detraining on enzyme histochemical and functional skeletal muscle characteristic in man Muscle Nerve 19 85, 8: 714 –722 Decramer M, de Bock V, Dom R: Functional and histologic...

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Báo cáo khoa học: "Skeletal muscle oxygen saturation does not estimate mixed venous oxygen saturation in patients with severe left heart failure and additional severe sepsis or septic shock" docx

Ngày tải lên : 13/08/2014, 03:20

... (n = 41) P value Heart rate (beats/min) 11 1 ± 21 111 ± 24 11 1 ± 19 0.9 SAP (mmHg) 12 0 ± 22 12 2 ± 25 11 9 ± 22 0.8 DAP (mmHg) 73 ± 21 71 ± 22 74 ± 22 0.7 PAPs (mmHg) 56 ± 14 57 ± 13 56 ± 12 0.2 ... 4 .1 ± 2.5 3 .1 ± 2 .1 0 .1 CRP (mg/l) 11 0 ± 84 78 ± 72 12 8 ± 86 0.02 PCT (mg/l) 5.0 ± 6.0 2.5 ± 2.7 6.5 ± 6.8 0.02 10 6/l) 14 .1 ± 7.2 14 .5 ± 9.0 13 .9 ± 5.2 0.6 Haemoglobin (mg/l) 11 2 ± 14 10 9 ± 11 ... 11 11 4 ± 15 0 .1 Creatinine (μmol/l) 19 9 ± 16 5 15 6 ± 14 8 227 ± 18 6 0 .1 7.37 ± 0.03 7.38 ± 0.07 7.36 ± 0 .1 0.5 PCO2 (kPa) 4.8 ± 1. 0 4.7 ± 1. 1 4.9 ± 1. 0 0.4 PO2 (kPa) 16 .6 ± 8.0 17 .8 ± 10 .8 15 .9...

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Báo cáo khoa học: "Erythropoietin improves skeletal muscle microcirculation and tissue bioenergetics in a mouse sepsis model" ppsx

Ngày tải lên : 13/08/2014, 03:21

... (4.3) 294 (11 ) 293 (4) 12 .8 (0.8) 5.97 (1. 26) 1, 206.7 (12 8.6) 0.79 (0 .18 ) CLP+NS 73 (1. 8)c 68 (2.7)c 337 (30) 358 (29) 12 .1 (0.6) 1. 19 (0.35)c 938.8 (82.7)d 1. 94 (0.37)d CLP+EPO 70 (2.8)c 71 (3.0)d ... Hematology Hemostasis and Thrombosis at London Health Sciences Center, for providing the hematological laboratory support for this study References 10 11 12 13 14 15 16 Levy MM, Fink MP, Marshall ... systemic and intestinal O2 uptake during endotoxemia J Appl Physiol 19 88, 64:2 410 -2 419 Cain SM, Curtis SE: Experimental models of pathologic oxygen supply dependency Crit Care Med 19 91, 19 :603- 612 ...

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Na+, k+ ATPase in single skeletal muscle fibres and the effects of ageing, training and inactivity

Ngày tải lên : 04/12/2015, 13:59

... 11 0 XVIII 4.4.2 No decreases in [3H]ouabain binding in ageing 11 2 4.4.3 Methodological considerations - Single fibre and whole muscle homogenate western blotting in ageing 11 3 ... 12 1 5.2.8 Western Blots 12 1 5.2.8 .1 Western blotting analysis 12 2 5.2.9 [3H]ouabain binding site content 12 2 5.2 .10 Statistical Analysis 12 2 5.3 ... adaptation in skeletal muscle following intensified training, using RSE training in healthy young adults in Chapter and chapter HIT in the elderly in Chapter 51 Table 2.3 Exercise performance and skeletal...

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Basic Steps in Disaster-Recovery Planning

Ngày tải lên : 28/10/2013, 14:15

... procedures You should take into consideration the following aspects: Procedures for ensuring and maintaining physical security Coordination of restoration for the original site Restoration of electronic ... recovery, and the business can be up and running again According to statistical data, more than 75% of all companies in the United States rely on this technique This is understandable, since tape ... Contract and maintenance agreements Special operating instructions for sensitive equipment Cellular telephone inventory and agreements Miscellaneous Present the plan to all staff and train employees...

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Tài liệu Unit_8: Steps in problems solving ppt

Ngày tải lên : 21/12/2013, 20:15

... Assemble is one example of a machine……… printer, printing, print, printed a ……… your name and address in block letters b ……… was introduced by Gutenberg in Germany in the 14 00s c The quality of the……… ... computer is very intelligent It is capable of thinking III Locating information Find the place where the following ideas are expressed Programs are usually written on certain lined forms A block ... the instructions 10 does what it is told V Understanding words Find the synonyms for the following words construct takes a lot of time exact mistakes help Find the antonyms for the following...

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