stem cells riding cells and the synergistic induction of bone formation

... fat cells, various brain and nervous system cells, insulin-producing cells of the pancreas, bone cells, hematopoietic cells, yolk sac, endothelial cells, primitive endodermal cells, and smooth and ... called the trophoblast, and the cluster of cells inside the sphere is called the inner cell mass At this stage, there are about 70 trophoblast cells and about 30 cells in the inner cell mass The cells ... understanding the capabilities of adult stem cells is the relationship of the cellular environment to the concept of plasticity in adult stem cells Markus Grompe showed that HSCs and pancreatic stem...

Ngày tải lên: 15/03/2014, 09:20

... (2000); Identification of novel circulating human embryonic blood stem cells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stem cells into embryoid ... human pancreatic cell line in vitro and in vivo Mol Endocrinol 15, 476 - 483 Dzierzak, E et al (1998); Embryonic beginnings of definitive hematopoietic stem cells Ann N Y Acad Sci 872, 256 - 262 ... 814 - 822 Jones, G M., et al (2000); Human embryonic stem cells technology Semin Reprod Med 18, 219 - 223 Orlic D et al (2001); Bone marrow cells regenerate infarcted myocardium nature 410, 701...

Ngày tải lên: 02/04/2014, 22:20

... 2011, searchers have transplanted the bone marrow stem cells into the necrotic femoral heads, and results show bone marrow stem cells can remove vascular lesions and promote angiogenesis in necrotic ... ischemic, stem cells in circulation are adherent to the vascular endothelial cells, cross the endothelial cells, migrate and finally reached at ischemic sites Inflammatory may be observed in the local ... mesenchymal stem cells: feasibility and safety from monkey to human Stem Cells Dev,2006,15(3):349-357 Devine SM, Bartholomew AM, Mahmud N, et al Mesenchymal stem cells are capable of homing to the bone...

Ngày tải lên: 25/10/2012, 11:18

... inhibition was the consequence of a blockade in virus replication and no to host cells death The validity of these findings was provided by the inclusion of HSV-1 KOS and HSV-1 F strains in the experiments ... formation Since there is no published data on the effect of IFNs on HSV-2 infection in Vero cells the capacity of human IFNα and/ or IFN-γ to inhibit the replication of HSV-2 strains MS and G was initially ... combination and infected with HSV-2 (MS or G strain) at the MOI of PFU per cell HSV-1 (KOS and F strains) were also tested using the same MOI and served as controls The efficiency of HSV-1 strains KOS and...

Ngày tải lên: 20/06/2014, 01:20

... culture and cell surface epitope characterisation of IPFP cells The cells isolated from the IPFP proliferated in culture and reached confluence by day 14 The yield of cells by the end of passage ... CD105 (markers for mesenchymal stem cells) , and for CD29 (β1 integrin) The cells stained poorly for LNGFR and STRO-1 (markers on freshly isolated bone marrow stem cells) and sparsely for 3G5 (marker ... characterisation and showed the increase in fluorescence (green) compared with the autofluorescence (black) Chondrogenic culture of IPFP cells and the effect of low oxygen tension The cultured cell...

Ngày tải lên: 09/08/2014, 10:20

... reports of the effects of FGF-2 on bone marrow-derived mesenchymal stem cells [25-27] and has important implications for the role of FGF-2 in tissue engineering applications of these cells There ... staining of IPFPderived cells It was therefore interesting that they showed a pattern of expression on a high proportion of the IPFP-derived cells and of epitopes commonly abundant on adult stem cells ... with further culture [41-44] Another possibility is that the expression of 3G5 could be due to culture conditions and not the reminiscence and the demonstration of a cell origin, and further work...

Ngày tải lên: 09/08/2014, 10:23

... of proteoglycans after pellet co-culture of disc cells with BM-MSC [20] Stimulation of disc cells with stem cells or CM could enhance the success of autologous implantation of disc cells In the ... 50:50 ratio of AD-MSC and annulus cells in coculture compared with the predicted value calculated from the sum of the proteoglycan contents of individual cultures of ADMSC and annulus cells Data ... either cell type enhancing the overall ECM production, or by modification of the microenvironment of the 3D matrix through deposition of ECM components by either the AD-MSC or the annulus cells...

Ngày tải lên: 09/08/2014, 10:23

... Mesenchymal stem cells and their potential as cardiac therapeutics Circ Res 95, 9–20 Quesenberry, P.J., Aliotta, J.M., 2008 The paradoxical dynamism of marrow stem cells: considerations of stem cells, ... identified Thesis The specific aims of this PhD project were to identify the active cardioprotective factor of the MSCs secretion and to elucidate the mechanisms of the cardioprotection The findings ... Mesenchymal Stem Cells In The Treatment Of Acute Myocardial Infarction With the emergence of stem cells as potential regenerative medicine, attempts to use stem cells to reduce infarct size and enhance...

Ngày tải lên: 10/09/2015, 08:42

... stromal stem cells J Cell Sci Suppl :63-76 123 Beresford JN 1989;Osteogenic stem cells and the stromal system of bone and marrow Clin Orthop Relat Res (240):270-280 124 Caplan AI 1991;Mesenchymal stem ... niche, self-renewal and differentiation Arthritis Res Ther (1):204 121 Owen M, Peck W 1985;Lineage of osteogenic cells and their relationship to the stromal system In ed Bone and MineralAmsterdam ... 31 Schofield R 1978 ;The relationship between the spleen colony-forming cell and the haemopoietic stem cell Blood Cells (12):7-25 32 Moore KA, Lemischka IR 2006 ;Stem cells and their niches Science...

Ngày tải lên: 11/09/2015, 09:16

... Introduction 1.1 Stem cells Stem cells have the remarkable potential to differentiate into specialized cells and thereby are key factors for the development of the whole organism All types of stem cells ... by the integration of wild-type genes into the AAVS1 locus The use of AAVs was further simplified by the arrival of commercially available systems Following the hypothesis that homology of the ... Reynolds and Weiss, 1992; Urbach et al., 2004) Neural stem cells of this process can give rise to neurons and glia, the two lineages most cells of the central nervous system belong to, and are therefore...

Ngày tải lên: 26/11/2015, 09:54

... stem cells The nature and origin of the neural stem cell in the SGZ of the hippocampus has been also a subject of an intense debate, questioning whether they could be considered true neural stem ... especially relevant in the case of human samples because of their low availability 4 Neural Stem Cells and Therapy Therefore, the aim of this chapter is to recapitulate some of these technical differences ... stem cells and the different range of progenitor cells This will allow the study of their specific biological features and maybe modulate their behavior in vivo 20 Neural Stem Cells and Therapy...

Ngày tải lên: 30/03/2014, 23:20

... concentrate stem cells to an area of need, to modulate effects of stem cells once they are in that specific area, or even to use light together with other agents to modulate endogenous stem cells The ... induced in rats and the effects of daily He-Ne irradiation at 1.2 and 2.4 J/cm were assessed in comparison to 0.2% nitrofurazone cream The number of macrophages at day 16, and the depth of new epidermis ... regeneration of the rat mid-cortical diaphysis of the tibiae, which is a model of post-injury bone healing A small hole was surgically made with a dentistry burr in the tibia and the injured area and...

Ngày tải lên: 18/06/2014, 16:20

... Cancer Center of Sun Yat-Sen University All the patients underwent radical surgery, and none of them had undergone either chemotherapy or radiotherapy before the collection of the samples The histopathologic ... mast cells and its relationship with the progression of colon cancer to identify the role of mast cells in this process Therefore, the current study examined the mast cell counts in primary and ... Committee of our institution Patients were informed of the investigational nature of the study and provided their written informed consent The count of tryptase-positive mast cells in the cancer...

Ngày tải lên: 18/06/2014, 19:20

... Cancer Center of Sun Yat-Sen University All the patients underwent radical surgery, and none of them had undergone either chemotherapy or radiotherapy before the collection of the samples The histopathologic ... mast cells and its relationship with the progression of colon cancer to identify the role of mast cells in this process Therefore, the current study examined the mast cell counts in primary and ... Committee of our institution Patients were informed of the investigational nature of the study and provided their written informed consent The count of tryptase-positive mast cells in the cancer...

Ngày tải lên: 20/06/2014, 03:20

... http://www.ovarianresearch.com/content/2/1/20 The binding of FSH and/ or LH in granulosa cells to its own receptors led to rapidly and nongenomic activation of PKA, p38 MAPK, and PI3K in a cAMP-dependent manner [16] and of ERK1/2 via the ... detected The addition of H89 or SB20580 to the medium significantly decreased the intensity of bands as compared with those in cumulus cells of COCs cultured without any inhibitor, and these inhibitory ... pathway played dual roles in cumulus cells One role is the induction of EGF-like factor and TACE/ADAM17 expression The other is direct induction of cumulus expansion of porcine COCs In granulosa cell...

Ngày tải lên: 20/06/2014, 07:20

... receptors and ligands of the IGF system Purple represents the alpha and beta subunit of IGF-1R; red represents the alpha and beta subunit of the IR-B; orange represents the alpha and beta subunit of the ... to the over simplicity of the model, the instability of the strain, the existence of “false cell lines” and the failures of representativeness of the tumour Thus, it clearly appears that these ... in the use and publication of these cells Shown is the total number of papers published using MDA-MB-435 cells (green bars) and the percent of the total number of publications use MDA-MB-435 cells...

Ngày tải lên: 27/06/2014, 17:20

... local injury and inflammation there is local up-regulation of Wnt signaling and the activity of ␤-catenin, and that this is then switching some of the cells to become progenitors of intestine.” ... at the surface of a cell, it blocks degradation of the co-factor ␤-catenin and frees it to interact with the transcription factors of the TCF/LEF family, thereby triggering the transcription of ... whether the cells that give rise to the metaplasia are progenitor or stem cells, or a more differentiated cell type Because of the way their experiment was set up, Hogan favors the notion that the...

Ngày tải lên: 06/08/2014, 18:21

... the body and large numbers of ES cells can be relatively easily obtained in vitro culture Therefore, ES cells could be the choice of cells in stem cell therapy for various diseases One of the critical ... into the cavity of an expanded blastocyst, ES cells give rise to chimeric mice in which ES cells take part in the development of all types of tissue including the germ line [62] Applications of stem ... Gokhale PJ, Andrews PW Culture and characterization of human embryonic stem cells Stem Cells Dev 2004, 13, 325-336 18 Drukker M, Benvenisty N The immunogenicity of human embryonic stem- derived cells...

Ngày tải lên: 07/08/2014, 18:21

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Ngày tải lên: 07/08/2014, 18:21