stem cells and signals for tissue regeneration

... remaining stem cells for tissue regeneration and repair? In conclusion, MSCs derived from adult tissue present an exciting progenitor cell source for applications of tissue engineering and regenerative ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymal stem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stem cells are found ... engineering and regeneration [134] Mesenchymal stem cells versus embryonic stem cells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can...

Ngày tải lên: 09/08/2014, 01:21

... Feinberg AP: Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts Nat Genet 2009, 41:1350-1353 ... embryonic stem cells and differentiation Nat Rev Mol Cell Biol 2006, 7:540-546 51 Park SH, Kook MC, Kim EY, Park S, Lim JH: Ultrastructure of human embryonic stem cells and spontaneous and retinoic ... Rada-Iglesias A, Wysocka J: Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease Genome Medicine 2011, 3:36 ...

Ngày tải lên: 11/08/2014, 12:21

... Stem cells circulate among tissues, and stem cells migrate to the injured tissues once injury occurs Stem cell homing is a complicated process in which a lot of molecules were involved Once tissues ... application of stem cells provides promise for the treatment of ischemic femoral head necrosis When compared with vascular intervention and local drilling for injection, transplantation with stem cells ... molecules, and stem cells are motivated and migrate into peripheral blood and target tissue, in which specific receptors or http://www.medsci.org Int J Med Sci 2011, ligands expressed in injured tissues...

Ngày tải lên: 25/10/2012, 11:18

... brain and nervous system cells, insulin-producing cells of the pancreas, bone cells, hematopoietic cells, yolk sac, endothelial cells, primitive endodermal cells, and smooth and striated muscle cells, ... PROJECT OVERVIEW AND DEFINITIONS ADULT STEM CELLS 19 EMBRYONIC STEM CELLS 31 OPPORTUNITIES FOR AND BARRIERS TO PROGRESS IN STEM CELL RESEARCH FOR REGENERATIVE MEDICINE 41 FINDINGS AND RECOMMENDATIONS ... between adult and embryonic stem cells and among adult stem cells found in different types of tissue The implications of these biological differences for therapeutic uses are not yet clear, and additional...

Ngày tải lên: 15/03/2014, 09:20

... embryonic and adult neural stem cells in both invertebrates and vertebrates, and highlights the history and the most advanced discoveries in neural stem cells This book provides the strategies and ... Formation of Nervous Systems and Neural Stem Cells in Ascidians 121 Kiyoshi Terakado Chapter Regeneration of Brain and Dopaminergic Neurons Utilizing Pluripotent Stem Cells: Lessons from Planarians ... (slowly dividing astroglial cells and the bona fide adult neural stem cells) , type C cells (transit-amplifying cells derived from asymmetric division of Type B cells) , type A cells (immature neuroblasts...

Ngày tải lên: 30/03/2014, 23:20

... pEGFPn3 (Clontech) and sequenced on both strands Tissue extraction Mouse spinal cord tissue Animals were handled in accordance with standard ethical guidelines (NIH Guide for Care and Use of Laboratory ... limit was 10 fmol for NPFF-derived peptides, 55 fmol for hNPAF and 520 fmol for QFW-NPSF HPLC fractions were collected every 60 s for gradient 1(HPLC-1) and (HPLC-2), every 30 s for gradient (HPLC-3) ... performed on frozen tissue: sonication in 0.1 M HCl, followed by boiling for 10 Tissue homogenates were buffered to pH 7.4 with M Tris pH 7.4, at a final concentration of 25 mg tissue mL)1 and...

Ngày tải lên: 31/03/2014, 07:20

... novel circulating human embryonic blood stem cells Blood 96, 1740 - 1747 IItskovitz - Eldor, J and et al (2000).; Differentiation of human embryonic stem cells into embryoid bodies comprising the ... al (1998); Embryonic stem cells lines derived from human blastocysts Science 282, 1145 - 1147 12 Raisman, G., (2001); Olfactory ensheathing cells - another miracle cure for spinal cord injury? ... tham khảo Amit et al (2000); Clonally derived human embryonic stem cell lines maintain pluripotency and proliferative potential for prolonged periods of culture Dev Biol 227, 271 - 278 Beltrami,...

Ngày tải lên: 02/04/2014, 22:20

... He-Ne-based laser for adherent cells that may be useful in regeneration such as fibroblasts and mesenchymal stem cells Studies have also been performed in vitro on immunological cells High intensity ... at 28 and 112 J/cm2 of human peripheral blood mononuclear cells, a heterogeneous population of T cells, B cells, NK cells, and monocytes has been described to induce chromatin relaxation and to ... rationale for stem cell-based COPD treatments, we began our exploration into this area by performing several preliminary experiments and filing patents covering combination uses of stem cells with...

Ngày tải lên: 18/06/2014, 16:20

... breast tissue normal mammoplasty (transformed) normal mammoplasty (transformed) primary tissue primary tissue primary tissue primary tissue primary tissue lymph node primary tissue primary tissue ... 1998 origin primary tissue primary tissue pleural effusion primary tissue primary tissue primary tissue primary tissue primary tissue primary tissue primary tissue primary tissue pleural effusion ... Microenvironment, Stem Cells and Metastasis McAteer, J., and Davis, J (2002) Basic cell culture technique and the maintenance of cell lines (Oxford, England, Oxford Press) McGarrity, G., and Coriell,...

Ngày tải lên: 27/06/2014, 17:20

... adult stem cells (such as blood-forming hematopoietic stem cells and cartilage-forming cells) A potential advantage of using adult stem cells is that the patient's own cells could be expanded ... these cells are allowed to attach again and form outgrowths, embryoid bodies can give rise to differentiated tissues such as myocardium, blood islands and hematopoietic stem cells [16,51] ES cells ... blastocyst, ES cells give rise to chimeric mice in which ES cells take part in the development of all types of tissue including the germ line [62] Applications of stem cells for tissue repair and transplantation...

Ngày tải lên: 07/08/2014, 18:21

... ectopic bone formation of embryonic stem cells and cord blood stem cells in vivo Tissue Eng Part A 2010, 16:2475-2483 Luo JZ, Xiong F, Al-Homsi AS, Roy T, Luo LG: Human BM stem cells initiate ... embryonic stem cells Head Face Med 2008, 4:10 doi:10.1186/1746-160X-7-5 Cite this article as: Handschel and Meyer: Infection, vascularization, remodelling - are stem cells the answers for bone ... Transplant 2010 Meyer U, Meyer T, Handschel J, Wiesmann HP: Fundamentals of Tissue Engineering and Regenerative Medicine Berlin, Heidelberg: Springer-Verlag; 2009 Handschel J, Berr K, Depprich RA,...

Ngày tải lên: 11/08/2014, 20:20

... rat MSC and primary rat endothelial cells (10 apneic and 10 control rats for each assay) Mesenchymal stem cells The study was performed on well-characterized Lewis rat marrow stromal cells kindly ... marrow stromal cells Stem Cells 2001, 19:219-25 10 Burt RK, Loh Y, Pearce W, Beohar N, Barr WG, Craig R, et al.: Clinical applications of blood-derived and marrow-derived stem cells for nonmalignant ... [1113], as well as for several respiratory pathologies [14-17] It has been proven that, in addition to their capacity for tissue regeneration by homing at the injured tissue and differentiating...

Ngày tải lên: 12/08/2014, 11:22

... augment resident stem cells, and we comprehensively review such data from lung Finally, there is great hope that embryonic stem cells, embryonic germ cells, or even adult somatic stem cells can be ... mast cells, and macrophages, has hindered identification of lung stem cells and patterns of cell migration during tissue renewal Nevertheless, the prevailing view is that airway basal and Clara cells ... stem/ progenitor cells or delivery of adult somatic stem cells, embryonic stem cells, or embryonic germ cells may theoretically improve barrier function, supporting the notion of treating a "stem...

Ngày tải lên: 12/08/2014, 18:21

... Hematopoietic Stem Cells and Progenitors: Implications for Clinical Application Annual Review of Immunology 2003, 21:759-806 Reya T, Morrison SJ, Clarke MF, Weissman IL: Stem cells, cancer, and cancer stem ... cell types, including hematopoietic and stromal cells of the bone marrow, endothelial cells, epithelial cells, fibroblasts, neuronal cells, and smooth muscle cells [3,53-57] The bone marrow is ... that Bmi-1 is required for the activation and survival of pre-T -cells and during transition from DN to DP T -cells [157] Bmi-1 is required for the proliferation of LSC/CSCs, and the deregulation...

Ngày tải lên: 12/08/2014, 23:23

... cardiac tissue mainly through cardiac and vascular tissue growth and regeneration (Caplan and Dennis, 2006b; Liu and Hwang, 2005) This paracrine hypothesis could potentially provide for a noncell-based ... rights and privacy, and to provide confidential counseling for patient's fully informed consent to voluntary donation TOP for fetal abnormalities and sexual assault cases and in minor (16 and below) ... Mesenchymal Stem Cells In The Treatment Of Acute Myocardial Infarction With the emergence of stem cells as potential regenerative medicine, attempts to use stem cells to reduce infarct size and enhance...

Ngày tải lên: 10/09/2015, 08:42

... underlying human nervous system development (Ben-Nun and Benvenisty, 2006; Dvash et al., 2006) 2.7 Embryonic stem cells and induced pluripotent stem cells Embryonic stem cells (ESC) have two characteristics ... and Jayanthi for i running the lab so smoothly and my students Huizi, Huishan, Su Fung, Huiling, Jin Ju and Lydia for your helping hands The administrative staff in BTI who are so efficient and ... people in my life, Mum, Dad and Sam, for your unfailing love and confidence in me Mum and Dad, I am so blessed to have parents that pray for me daily And finally, to my husband Stephen Words cannot...

Ngày tải lên: 11/09/2015, 10:14

... B and T cells leading to proliferation and the generation of antibodies (for B cells) and the generation of armed effector T cells such as cytotoxic T cells and helper T cells (Th) (for T cells) ... lymphocytes [CTLs], helper T cells and Tr cells) traverse inflamed epithelia and reach the injured tissue, where they eliminate microbes and/ or microbe-infected cells (e) Activated B cells migrate into ... immune system is immediate, mediated by neutrophils, natural killer cells (NK), macrophages and dendritic cells, cells that phagocytose and kill the pathogens Among the innate immune cells, dendritic...

Ngày tải lên: 14/09/2015, 08:24

... thigh region, and used lentiviruses to induce the cells to pluripotent cells These pluripotent cells are studied and characterized The pluripotent stem cells exhibited morphology and genomic markers ... cardiomyocytes for cell therapy (Odorico, Kaufman, & Thomson, 2001) The cardiomyocytes must be pure, and no parental stem cells should be used as stem cells are oncogenic and will result in the formation ... porcine embryonic stem cells have been isolated, induced pluripotent stem cells for the pig must be used as a source of pluripotent cells Hence, fibroblasts from the pig is taken, and induced into...

Ngày tải lên: 30/09/2015, 10:13

... embryonic stem cells 1.1.1 Overview and characteristics of human embryonic stem cells 1.1.2 Regulatory networks and transcription factors in human ES cells 1.1.3 Induced pluripotent stem cells 1.1.4 ... million cells per ml and blasted into single cells Cell sorting was performed using the MoFlo sorter (Beckman Coulter) Page 27 Forward and side-scatter plots were used to exclude dead cells and debris ... were 24bp and 34 bp for shortSAGE and longSAGE library, respectively Database was managed with MS access and numerical analyses were preformed with MS Excel Cancer and normal tissue and EC cell...

Ngày tải lên: 16/10/2015, 11:58