specialized procedures in the management of patients with rheumatic diseases

... subjects received their first dose of aripiprazole at the start of the switching treatment period, the starting dose of which was determined by the investigator After weeks of adverse event (AE)-free ... receiving >20 mg/day Of the 153 patients enrolled in the study, 106 patients (69.2%) were compliant with treatment During the 12-week switching period, no patients received diphenhydramine and ... during the switching treatment phase This finding, coupled with the improvement in QOL ratings, is important as it provides an estimation of the real-world impact of antipsychotic treatment with...

Ngày tải lên: 09/08/2014, 01:21

... common in the group whose position was varied than in the group that remained continuously supine Con: prone positioning is not useful in the management of ARDS patients Gordon Rubenfeld Imagine the ... Finally, intensivists are strongly motivated by the ‘rule of rescue’ Intensivists feel obliged to offer some therapy, any therapy, to a patient in imminent danger of dying [16] As is often the ... lung injury [8] Clinical experience Prone positioning has improved arterial oxygenation in all studies in patients with ARDS that have examined the question, especially in the early phase of illness...

Ngày tải lên: 12/08/2014, 18:21

... useful in the management of septic shock Katherine G Craig and Keith R Walley The debate surrounding the use of corticosteroids in septic patients has continued for over 30 years Two metaanalyses in ... yet preliminary, The patient described in the present scenario is improving in all aspects of organ failure, but remains catecholamine dependent A thorough examination and review of his management ... groups [8] There is ongoing debate in the literature as to the usefulness of this corticotropin stimulation test in so-called ‘relative adrenal insufficient’ patients, although it may be of prognostic...

Ngày tải lên: 12/08/2014, 18:21

... difference in the rate of infection of pancreatic necrosis [4] Pooling of the data from these 183 patients by Bosscha and colleagues in a meta-analysis resulted in a group of 95 patients treated with ... used intravenous and enteral antibiotics (including amphotericin) to achieve decontamination of the gastrointestinal tract for the purpose of possibly decreasing bacterial inoculation of the necrotic ... selective decontamination of the digestive tract Selective decontamination is attractive as it may allow the use of prophylaxis without the risk of inducing superinfections through the use of long-term...

Ngày tải lên: 12/08/2014, 19:22

... pointes Unlikely Risk of liver injury in conjunction with lipid-lowering agents; risk of bleeding complications in conjunction with antiplatelet agents, warfarin, niacin Induction of CYP3A4 increases ... gabapentin in patients with HCV [55] These findings suggest that valproate can be used for some patients with HCV without adversely affecting ALT levels Obtaining pretreatment baseline ALT levels in ... syndrome), including carbamazepine, phenytoin, phenobarbital, and lamotrigine The triad of hypersensitivity includes fever, rash and internal organ involvement with onset of symptoms within to weeks of...

Ngày tải lên: 25/10/2012, 10:51

... photocopy of each form before sending it 24 The management of patients with venous leg ulcers Appendix 2: Audit Form The management of patients with venous leg ulcers Notes 25 26 The management of patients ... audit form The purpose of clinical audit is to improve the quality of care to patients locally It is intended that by providing nationally-produced guidelines and The management of patients with venous ... of occurrence of the first ulcer; the site of the ulcers and of any previous ulcers; the number of previous episodes of ulceration; the time taken to heal in previous episodes; the time free of...

Ngày tải lên: 15/03/2014, 23:20

... zygapophyseal joints in patients with AS [10] In the present study, we first examined whether inflammation in the spine of patients with AS, as detected by histopathology, can be correlated with bone ... highest score of bone marrow infiltation in the histopathological assessment Some of the patients had inflammatory lesions in other parts of the spine, as indicated in Table Page of (page number ... illustration of the anatomy and detection of inflammation in the bone marrow The entire lumbar spine including the zygapophyseal joints and, if available, the thoracic spine was analyzed for increased...

Ngày tải lên: 09/08/2014, 08:22

... was the principal investigator of the OASIS study and is the principal investigator who assisted in designing the ATLAS study WPM is the principal investigator and assisted in designing the Canadian ... Goldstein N, Braun J, Ankylosing Spondylitis Study for the Evaluation of Recombinant Infliximab Therapy Study Group: Radiographic findings following two years of infliximab therapy in patients with ... based on their experience with musculoskeletal imaging and experience in reading spinal imaging studies of patients with AS However, none of the assessors was familiar with the OASIS films The assessors...

Ngày tải lên: 09/08/2014, 14:22

... finding should be interpreted in the context of the newly established network One of the aims of ParkinsonNet is to better integrate primary care professionals in the treatment of patients with ... variation of individual network characteristics for all measures in both the network of ‘knowing each other’ and in the network of ‘having professional contact.’ For example, the number of others ... Consistent with the pattern in the total network, mean and maximum values of the network measures were highest in the network of knowing each other Table shows the same 12 measures in the predefined...

Ngày tải lên: 10/08/2014, 11:20

... sustained The findings further indicate that the use of US imaging of the foot would be more beneficial than clinical examination alone in the refinement of diagnosis and the implementation of ... beneficial in monitoring the progression of active inflammation in rheumatoid arthritis [13] and in the monitoring of biologic therapy [14-16] The aim of this study was to evaluate by means of US, the ... and foot pain and no account was taken of the mechanical forces of foot function during gait as this was not feasible within the confines of our study Others, having investigated the association...

Ngày tải lên: 10/08/2014, 21:24

... transduction in B cells The interaction with TRAFs induces the nuclear factor (NF)-B signaling pathway, which plays a pivotal role in regulating diverse aspects of immune function, including mediating inflammatory ... difference in detectable levels of BLyS was found in patients with RA (33%) compared with the healthy donor samples (18%) (Table 1) Within the samples containing detectable levels of the three ... form of BLyS The molecular mass of the heterotrimers was confirmed by SEC-MALS mass distribution LS/UV/RI 3-detector analysis Binding kinetics and affinity studies The binding affinities and kinetics...

Ngày tải lên: 12/08/2014, 12:20

... associated with off-label use of FVIIa, the majority occurring in trauma patients However, MedWatch is a database for voluntary reporting of observed complications, and therefore the incidence of complications ... (upper gastrointestinal bleeding) without any evidence for the drug’s efficacy and safety The first issue is the off-label use After a single successful report of off-label use of recombinant FVIIa ... Recombinant activated factor VIIa in an unselected series of cases with upper gastrointestinal bleeding Thromb Res 2005, Epub ahead of print 18 Rizoli SB, Chughtai T: The emerging role of recombinant...

Ngày tải lên: 12/08/2014, 23:24

... significant improvements in oxygenation within hours of HFOV initiation, allowing a majority of patients to benefit from a decrease in FiO2 Ventilation was maintained with HFOV, and there were no adverse ... that the survival of adult patients with ARDS is improved with the use of HFOV Animal data Most of the studies published over the past 40 years comparing HFOV with CMV have favored HFOV [9] In ... controlled trials of high-frequency ventilation in infants have been performed, with nine of these trials using HFOV [12] The overall results of these trials are equivocal In a meta-analysis,...

Ngày tải lên: 12/08/2014, 18:21

... the number of male patients was higher in the index cases, but the number of female patients was higher in contacts determined active disease In our opinion, the reason of this findings were that ... presence of cavity in the chest radiograph of index case increased the frequency of TB in household contacts In our country, Kolsuz et al found the frequency of TB in close contact of TB cases ... [7] Chee et al detected a rate of 0.9% TB patients in investigation of 5699 close contacts of 1374 index case in Singapore [8] In their study which they detected TB in 36 children younger than years...

Ngày tải lên: 29/03/2014, 03:20

... factors in patients with SMI Methods The aim of this literature review was to highlight the efficacy of lifestyle interventions based on diet and exercise in the management of CVD risk factors in patients ... 17.5% in women) [50] It is worth noting that in a study conducted in individuals with SMI in the community, 29% of men and almost 60% of women with SMI were obese [51] The prevalence of obesity in ... medication is not the sole underlying factor for weight gain in patients with SMI, as there are multiple factors contributing to the risk of obesity among patients with schizophrenia including poor dietary...

Ngày tải lên: 09/08/2014, 01:21

... unresolved issues is the inability to explain the nonrandom, selected organ injury that defines the WG vasculitis and the concurrent, seemingly random, nature of injury within ‘targeted’ organs ... the infiltrating cells were characterized as macrophages However, a few cells seemed to be endothelial cells This is in line with our recent findings of de novo synthesis of PR-3 in endothelial ... importance of PR-3 in the pathogenesis of WG, we sought to define the expression pattern of PR-3 in lung tissue Materials and methods Patients Normal tissues were obtained from five patients undergoing...

Ngày tải lên: 09/08/2014, 03:24

... 90% of 336 reported cases with technical failure reported in 8% of cases and perforation in 4% [12] In this series the technique of stenting was introduced and developed in the unit during the ... patients with surgically incurable CRC without resection of the primary tumour is the risk of the patient presenting acutely with obstruction, bleeding or perforation either at the time of diagnosis ... and in the future may reduce the need for emergency surgical intervention and stoma formation in patients presenting with malignant large bowel obstruction One of the concerns in managing patients...

Ngày tải lên: 09/08/2014, 04:21

... When testing the activity using SF of patients with RA, we found that while the percentage of inhibition of the NPA in the presence of inhibitor III rarely exceeded 10–15%, the level of inhibition ... microspheres, thereby minimizing interference with debris (Figure 1a, left panel) The NPA in the clinical sample is then obtained by measuring the mean fluorescence intensity resulting from the loss of ... simply the presence of proteases, in patients during the course of their disease and under the influence of treatment This may represent a sine qua non to achieve clinical success in the development...

Ngày tải lên: 09/08/2014, 08:22

... mRNA in osteoarthritis (OA) patients and the attempt to inhibit the potential signaling of DREAM in SFLCs using siRNA The targeted inhibition of the expression of DREAM in SFLCs might enhance the ... showed the binding of DREAM to DNA, which implied a role in the hierarchical machinery regulating the rat dynorphin-encoding prodynorphin (pdyn) gene in a Ca2+-dependent manner Dynorphin interacts ... role in pain transmission by regulating the transcription of pdyn in the spinal cord DREAM-/- mice showed less pain sensitivity in all paradigms tested [11] To inhibit the blocking function of the...

Ngày tải lên: 09/08/2014, 10:23

... analysis The clinical significance of these nodules is also unknown, since they could interfere with the surrounding branches of the greater and lesser occipital nerves and create most of the symptomatology ... obtain a true anteroposterior image of the cervical spine at the C1-C2 interspace, and the overlying skin was marked with a sterile marker Thereafter a portable ultrasound with a sterile linear ... surface The skin overlying the greater occipital protuberance was injected with ml or ml of 1% lidocaine as a local anesthetic, and the stimulating electrodes were introduced through a 14-gauge introducer...

Ngày tải lên: 11/08/2014, 00:23