imaging in the evaluation of patients with prostate cancer

... standards The opinion from the Ethics Committee of the coordinating investigator (Ärztekammer Sachsen-Anhalt) was sought for the final study protocol, including the final version of the Informed ... at the end of observation in the chemotherapy group compared with the other two groups challenges the interpretation of these data Conclusions Findings from the REASON study secondary endpoints ... combination chemotherapy to TKI/gefitinib therapy First-line therapy was continued as maintenance in 71 (22.2%) patients with EGFR Mut + NSCLC, mainly planned to be gefitinib (44 patients) There

Ngày tải lên: 24/07/2020, 00:35

... or HEC in patients with cancer APF530 was found to be noninferior to palonosetron in the control of acute CINV in patients receiving MEC or HEC and in the prevention of delayed CINV in patients ... palonosetron in the control of acute CINV in patients receiving MEC or HEC, and in the prevention of delayed CINV in patients receiving MEC [19] In this post hoc analysis of the study breast cancer ... data) (Fig 2) Within the subgroup of patients with breast cancer, 629 patients initiated cycle and were included in the safety population (431 MEC, 198 HEC), 608 of whom were included in the mITT

Ngày tải lên: 21/09/2020, 02:01

... marker within the study can define the positivity of CTCs), each of the subgroups was considered an independent data set However, as for studies with multiple time points (i.e., pre-therapy and intra/post-therapy ... conducted by alternating with data on the other time points With regard to studies from the same institutions, sensitivity analyses by excluding all of them or only keeping the latest study were ... phase II clinical trial evaluating the activity of single-agent lapatinib in patients with HER2-negative metastatic breast cancer and HER2-positive circulating tumor cells: a proof -of- concept

Ngày tải lên: 14/10/2020, 17:02

... and FOXP3 in Peripheral Blood Lymphocyte (PBL) of Patients with Liver Cancer and their Significance Ze-Wei Lin1, Li-Xuan Wu2, Yong Xie1, Xi Ou1, Pei-Kai Tian1, Xiao-Ping Liu1, Jun Min3, Jie Wang3, ... and FOXP in peripheral blood mononuclear cells (PBMC) of patients with hepatocellular carcinoma (HCC) and to evaluate the correlation between the imbalances of Th1/Th2, Th17/Treg at the expression ... Int J Med Sci 2015, Vol 12 Ivyspring International Publisher International Journal of Medical Sciences 2015; 12(1): 7-16 doi: 10.7150/ijms.8352 Research Paper The Expression Levels of Transcription

Ngày tải lên: 15/01/2020, 02:13

... available in doublet regimens and investigated the effectiveness of irinotecan-based chemotherapy regimen in improving the survival of patients with gastric cancer considering the rarity of irinotecanbased ... less considering the high heterogeneity and lack of targets in gastric cancer Therefore, systemic chemotherapy remains the current main treatment in patients with advanced gastric cancer [6] Especially ... analyses including whether the regimens included fluorouracil (FU), platinum, anthracycline, taxane, irinotecan (I), MMC, and others and whether the studies included either Asian or Western patients

Ngày tải lên: 17/06/2020, 19:11

... found that the size and number of tumors had an effect on the prognosis of patients The larger the tumor and the greater the number of tumors, the shorter the survival time is In line with the results ... OS rates of patients with adenocarcinoma in villous adenoma read last by finding the number on the “Total Points” scale Validation of the nomogram model To investigate the validity of the nomogram, ... from the SEER database Table lists the basic information regarding the demographic and clinical characteristics of the patients with adenocarcinoma in villous adenoma As shown in Table 1, of the

Ngày tải lên: 06/08/2020, 05:24

... for the diagnosis and monitoring of these cancers [20-24] The diagnostic value of serum YKL-40 in patients with ESCC remains unknown The goal of our present study is to investigate the levels of ... epithelial cell line NE-3, induced by human papillomavirus type 16 E6/E7, was obtained from Dr Jin (the University of Hong Kong, Page of 10 P.R China) and was cultured in Keratinocyte-SFM (Invitrogen, ... Laboratory of Oncology in Southern China, Guangzhou, China Department of Experimental Research, Sun Yat-sen University cancer center, Guangzhou, China Full list of author information is available at the

Ngày tải lên: 14/10/2020, 17:33

... diagnosis In stage I, cancer has formed in the inside lining of the mucosa (innermost layer) of the stomach wall, whereas in stage IV, cancer has spread to distant parts of the body Early gastric cancer, ... [1] In recent decades, the morbidity and mortality of gastric cancer have fallen down dramatically, with the decline first taking place in the countries with low incidence while the decline in the ... part of China Despite a slight increase from the 1970s to the early 1990s, remarkable declines in gastric cancer mortality were noticed in almost the entire population in China These declines

Ngày tải lên: 05/11/2020, 00:14

... in patients who continued on peginterferon beta-1a every weeks, and was maintained in the every weeks treatment group [6] Magnetic resonance imaging (MRI) results reflected the clinical findings, ... pharmacodynamic properties of protein therapeutics, including interferon beta-1a [2, 3] The approved dosing schedule of pegylated interferon beta-1a (peginterferon beta-1a) for relapsing-remitting multiple ... defined below  MRI-NEDA: no Gd + lesions at any scan after the beginning of the stated time period, and no new or newly-enlarging T2 hyperintense lesions at the end compared with the beginning

Ngày tải lên: 04/12/2022, 10:37

... Silverman DHS, Cumming JL, Small GW, et al assessment of the added clinical benefit of incorporating FDG-PET into the clinical evaluation of patients with cognitive impairment Mol Imaging Biol 2002;4:283–293 ... being the most common By the time patients are symptomatic v vi Preface with these disorders, they have undergone significant distinct alterations in brain metabolism The increasing use of brain ... and functional neuroimaging in the clinical workup are given context The clinical utility of brain positron emission tomography (PET), as with other imaging modalities, depends in part on how accurately

Ngày tải lên: 05/03/2014, 23:20

... of the ulcer and its surrounding skin. Serial measurement of size (length and width) of the ulcer is a reliable index of healing. Appropriate techniques include tracing of the margins, measuring ... of occurrence of the first ulcer; the site of the ulcers and of any previous ulcers; the number of previous episodes of ulceration; the time taken to heal in previous episodes; the time free of ... help the project team to test the development of the audit package and methodology. The projrct team is grateful to the participating sites for their input and feedback in the development of the

Ngày tải lên: 15/03/2014, 23:20

... ester-induced disruption of the CD4–Lck complex occurs within a detergent-resistant microdomain of the plasma membrane. Involvement of the translocation of activated protein kinase C isoforms. J ... showing that EGFR is initially concentrated in caveolae within lipid rafts, but rapidly moves out of this membrane domain in response to EGF [7]. The inefficient movement of ErbB2 out of these ... observed (Fig. 4C,E respectively). These findings support the view that GM3 is mainly involved in retaining ErbB2 in lipid- raft domains, but that it is not involved in ErbB2 phosphorylation. EGFR

Ngày tải lên: 23/03/2014, 10:21

... population in the joint in comparison with the circulation was observed in all patient groups. These are interesting findings with regard to the clinical differences between the diseases. First, the ... the groups (Fig. 3c). The range of CD25 bright CD4 + T cells in the inflamed joint in the patient groups with or without erosions was the same, with a median of 2.2% in both groups, as was the ... blood. The range of CD25 bright CD4 + T cells in the inflamed joint in the patient groups with or without RF was compara- ble, with medians of 2.3% in the RF-positive group and 2.4% in the RF-negative

Ngày tải lên: 09/08/2014, 01:23

... that in RA. Immunostaining in normal donors revealed the expression of both BMPs predominantly in the synovial lining layer, whereas in patients with RA the expression was more frequently found in ... signaling has been shown to be involved in the onset and progression of ankylosing enthes- itis in spondyloarthropathies and in the induction of osteo- phytes in OA [8,9]. Antagonism of BMP signaling ... at the same time increased the loss of proteoglycan from the cartilage matrix, thereby cer- tainly promoting the damage of the joint surface [10]. Thus, regenerative triggers in the treatment of

Ngày tải lên: 09/08/2014, 07:20

... ascertain the low maturation status of the immature B cells a combination of CD38, CD24, and CD10 was used The frequency of expression of CD24/CD10 was clearly increased within the remaining B ... all of the B cell populations decreased when analysing absolute numbers as shown in Table The majority of the surviving B cells was found within the IgD- populations This argues for a predominant ... treatment results in a total depletion of CD38 expressing B cells in BM The expression of CD38 in combination with IgD was analysed for further characteristics of B cell maturation in BM shortly

Ngày tải lên: 09/08/2014, 14:22

... elevated in the bronchoalveolar lavage fluid of patients with CF Matrix metalloproteinases, implicated in remodeling of inflamed areas of the lung, are found in excess in the lungs of patients with ... diphtheria toxin Exotoxin A catalyzes the transfer of the ADP-ribosyl moiety of nicotinamide adenine dinucleotide onto elongation factor 2, which then is inactive in protein synthesis Exotoxin ... surface binding of bacteria is not quantitatively important in the establishment of infection, it may be important for the initiation of an exuberant inflammatory response [33] The binding of pilin

Ngày tải lên: 13/08/2014, 13:20

... on the total score of the three research indexes include the improving level of pain on a VAS scale, the improving expansion of the lumbar spine and the improving daily living according to the ... - The effective study of EA in treating LBP with kidney failure type: + The level of pain, pain threshold + Improving the expansion of the lumbar spine + Activities of daily living + sEMG + The ... of the body and the smooth flow of the meridians It pointed out by the balance of the bioelectric properties, according to the rule Yin- Yang balance of the Yin-Yang theory

Ngày tải lên: 04/10/2014, 13:22

... patient with ALCAPA A: Preop injection into the dilated RCA and retrograde staining of the LCA and MPA B: Post-Op injection into the LCA from the left coronary sinus 61 Page | VII List of Tables ... MR-angiography in a patient with TGA showing the bifurcation of the pulmonary arteries in front of the aorta after ASO with Lecompte procedure Note the steep course of the aortic arch 55 ... correction of CHD involving the coronary arteries, and in patients with CHD including coronary artery anomalies (Angelini 2007; Hauser et al., 2001; Maiers & Hurwitz, 2008; Vogel et al., 1991), or in

Ngày tải lên: 20/05/2016, 20:50

... 0–0.2, suggesting the formation of single LHD phase with the intercalation of tetrahedrally-coordinated Mo species in the interlayer domains As a consequence, a slight shift in ‘c’ or interlayer ... seen in Fig [9, 10, 38] The c parameter of the Mo-containing LHD is higher than that of the hydrotalcite reference MAC-00, reflecting a successful intercalation of MoO42- anions into the interlayer ... filtration, washing with hot distilled water, and drying at 70 °C for 24 h The obtained solid was ground into powder In the case of preparation of the Mg/Al intercalated carbonate anion in the free

Ngày tải lên: 12/12/2017, 06:08

... members of the general public aware of the extraordinary human toll of abuse and neglect in the lives of children with and without disabilities? Is the abuse and neglect of children with and without ... know New York: Penguin Paavilainen, E., & Flinck, A (2013) National clinical nursing guideline for identifying and intervening in child maltreatment within the family in Finland Child abuse review, ... neglect in the lives of children with disabilities The challenge is to integrate prevention efforts within the context of the children’s day-to-day lives at home, in school, and the community Inherent

Ngày tải lên: 14/05/2018, 15:40