... Urine cadmium (μg/g of creatinine) Urinary Total NAG (U/g of creatinnine) Urinary NAG-A (U/g of creatinnine) Urinary NAG-B (U/g of creatinnine) Urine cadmium Urinary Total NAG Urinary NAG-A Urinary ... incadmiumexposed and controls Variables Cadmiumexposed (N = 50) Control group (n = 50) Urine cadmium (μg/g of creatinine) Urinary Total NAG (U/g of creatinine) Urinary NAG-A (U/g of creatinine) ... Consumption Usually Sometimes Never Urine cadmium ≤5 >5 (n) Urinary Total NAG (U/g of creatinnine) Urinary NAG-A (U/g of creatinnine) Urinary NAG-B (U/g of creatinnine) (92) (8) 3.67 ± 1.68 3.95 ±...
... contradictory results in the increase of liver enzyme levels in workers exposedto VCM [14,17,18] Maybe the increase of sample size would lead to significant difference in the level of other ... were usually in the normal range and our findings in fact show the changes of these tests in working population The clinical importance of these subtle changes of liver function in working populations ... used to reduce the number of false negatives [1] Previous studies have shown increase in liver transaminases in workers exposedto high levels of VCM [9,14-16] Our study showed mild increase in...
... abies / cytokinine/ métabolisme / cytokinine radiomarquée / dépérissement des forêts INTRODUCTION substrates It is as yet uncertain whether are also involved in the interconversion of Cks (Letham ... low but constant Within h about 73% of the initial radioactivity was incorporated into the plants BLF and Ingestad seedlings exhibited only small differences in the uptake kinetics (fig 1A) was ... stress, including soil acidification, nutrient shortage and phytotoxic aluminium ions (Al have been suggested to be an ), 3+ important factor causing the phenomenon of the novel type of forest decline...
... and Methods Experiment Transplants (2 + ) of beech (Fagus sylvatica L.) were rooted into m plastic tubes containing compost Tubes were sunk into the ground in open top chambers sited at Headley, ... same chambers during April 1988 Plants were rooted into compost Measurements of gas exchange (photosynthesis, transpiration and stomatal conductance) were made using a laboratory system (Taylor ... (1989) Characteristics photosynthesis, stomatal responses and water relations of Fagus sylvatica: impact of air quality at a site in southern Britain New Phyof tol in press U.K Terrestrial Effects...
... activity rhythms: effects of melatonin J Pineal Res 1988, 5:203-215 Slotten HA, Pitrosky B, Pevet P: Influence of the mode of daily melatonin administration on entrainment of rat circadian rhythms ... records of Rw, Tb and melatonin levels obtained in a rat (#1 in Table 1) that did not show desynchronization or a reduced night -to- day serum melatonin ratio Although melatonin levels in the animals ... VM: Pinealectomized rats entrain and phase-shift to melatonin injections in a dosedependent manner J Biol Rhythms 1993, 8:233-245 Lin MT, Chuang JI: Melatonin potentiates 5-HT(1A) receptor activation...
... Nevertheless, we confirmed these findings in preliminary studies exposing macrophage cultures to 0.05% DMSO (data not shown) To induce production of MMPs and proinflammatory cytokines, macrophages were challenged ... production of MMPs, TIMPs, and pro-inflammatory cytokines in human monocyte-derived macrophages and report that indeed, PHT and HPPH significantly modulate macrophage MMP and cytokine protein levels in ... these cells to contribute to the fibroblast-mediated degradation of exuberant ECM proteins seen in DIGO Since plaque-induced gingival inflammation exacerbates the manifestations of PHT-induced GO...
... Nevertheless, we confirmed these findings in preliminary studies exposing macrophage cultures to 0.05% DMSO (data not shown) To induce production of MMPs and proinflammatory cytokines, macrophages were challenged ... production of MMPs, TIMPs, and pro-inflammatory cytokines in human monocyte-derived macrophages and report that indeed, PHT and HPPH significantly modulate macrophage MMP and cytokine protein levels in ... these cells to contribute to the fibroblast-mediated degradation of exuberant ECM proteins seen in DIGO Since plaque-induced gingival inflammation exacerbates the manifestations of PHT-induced GO...
... rekindled in pre-clinical settings, and has encouraged investigators to further analyze the underlying mechanisms in vitro and in vivo [7-9] The roles of endogenous PGE2 and of fluctuations in ... in the presence of exogenous PGE2 might be the result of less infiltrated inflammatory cells producing such PG within the airways Sulprostone neither reduces inflammation nor alters the HDM-induced ... analysis of airway EP receptor expression in the presence of EP receptor agonists brings us to a similar conclusion Exogenous PGE2 does not prevent the HDM-induced increase in EP2, but sulprostone...
... switching to a hypothetical reduced risk nicotine product in the future Reasons for not previously considering switching to ST or pharmaceutical nicotine to stop smoking but continuing to use ... as smoking There are things I enjoy about smoking besides just getting nicotine Smoking is important to my social life Reasons for not previously considering switching to ST to stop smoking but ... quitting smoking, but continuing to use nicotine, by switching from smoking to this product? 90% (86%, 94%) 60% (54%, 66%) 56% (50%, 62%) Reasons for not considering switching1 I believe that using...
... response to cadmium, approximately 21% of the 237 cadmium- inducible genes (≤1.5-fold) are involved in the resistance tocadmium toxicity (although these genes certainly could also be involved in detoxification ... largely only cadmium detoxification genes are over-expressed By using RNAi to examine the role of 92 cadmium responsive genes in the resistance tocadmium toxicity, we find that 50 of these genes ... and resistance tocadmium toxicity, the effects of inhibiting the expression of the cadmiumresponsive genes in the presence or absence ofcadmium on C elegans growth were determined information...
... advantages of tomato include the high biomass yields (about 68,000 kg/ha, approaching the yields possible in tobacco) and the increased containment offered by growth in greenhouses Instead of introducing ... are shown in gray and light chains in pink Solid black lines indicate continuation of the polypeptide backbone (simple lines indicate the constant parts of the antibody, curly lines indicate the ... expressed inplants Heavy-chain derivatives are shown in gray and light-chain derivatives in pink Solid black lines indicate continuation of the polypeptide backbone (simple lines indicate the...
... your pen-and-ink drawing will be apt to incline too much to a scratchy and broken kind of shade For instance, the texture of the white convent wall, and the drawing of its tiled roof, in the vignette ... lightly, and putting a multitude of little touches, crossing and recrossing in every direction, you will gradually be able to work up to the darker tints, outside of each, so as quite to efface their ... must not attempt anything of this kind When you are first sketching the leaves, shut one of your eyes, fix a point in the background, to bring the point of one of the leaves against; and so sketch...
... cycle [11–15] Certain transacting proteins such as HuR were proposed as regulators of changes in mRNA stability during the cell cycle [15] In this context it is of interest that during vertebrate ... thymidine ⁄ amphidicolin block, the half-life of cyclin B1 mRNA measured after actinomycin D addition increased from 1.2 h in early G1 to 12 h in G2 ⁄ M phase [11] With the same method the cyclin ... reported to change from 1.6 h in early G1 to 12 h in late G1 and h in S and G2 ⁄ M phase [12] Similarly, cyclin A and B1 mRNA half-lives increased in RKO cells from about 2.5 h in G1 to 18 h in S...
... + + + + to + + + + + to + + + + + to + + + - to + + + to+ + + + + to + + + + + + to + + + + + to + + + ++ - to+ + to+ + ++++ + + to + + + + + + to + + + + + to + + + Page of 12 (page number not ... embedded in paraffin Haematoxylin and eosin stained, five micron thick sections, were used for histopathological evaluation of lung inflammation Remaining lung tissue was snap frozen in liquid ... greater health risk to swine barn workers [8] exposure Our data show that lungs of rats exposedto the barn air remain capable of mounting an effective innate inflammatory response to a secondary...
... in which polypharmacy can be identified, including its role in precipitating hospital attendance, leading to corrective action being initiated, particularly in patients being sent home [10] In ... close level of monitoring of therapeutic anticoagulation in dedicated anticoagulation clinics in the hospital, and of wider awareness of the potential for drug interactions with warfarin • Hospital ... warfarin is used in a significant number of elderly patients, we were unable to find any drug combinations leading to potential adverse interaction with warfarin usage This may be because of the...
... band-matching process, based on a 1.5% position tolerance, was used to obtain presence-absence matrixes, allowing the classification of individual bands according to their positions in gels and ... basis led to the classification of the profiles into two categories (Fig 2) For the first year of sampling, farms B and C could be distinguished from farms A and D with respect to dominant OTUs In particular, ... respectively In addition to this observation of coincident bands, cloning and DNA sequencing were also used to identify some of the most frequent OTUs observed in raw milk Clones of Clostridium-specific...
... the specimens with at least 13 mm (1⁄2 in. ) of water The ratio of the volume of water to a volume of the bars shall not exceed toto prevent excessive leaching Replenish the water with fresh water ... and 1100 g of sand The amount of mixing water shall be 194 mL for all non-airentraining portland cements and 184 mL for all air-entraining portland cements 9.2 Mix the mortar according to the procedure ... off flush with the top of the mold and smooth the surface with a few strokes of the trowel 10.2 Storage of Test Specimens: 10.2.1 Initial Storage—Cure the specimens in the molds in the moist closet...
... TGF-beta1 and bleomycin intracellular signaling through autocrine regulation of Smad binding to the proximal promoter of the Smad gene J Cell Biochem 2006, 97(5):933-939 13 Rubin P, Johnston CJ, Williams ... Hamazaki Y, Shinkai H, Nishioka K: Animal model of sclerotic skin I: Local injections of bleomycin induce sclerotic skin mimicking scleroderma J Invest Dermatol 1999, 112(4):456-462 Page of 15 Yarnold ... no/minimal change in breast appearance Transcriptional response of cultured fibroblasts exposedto bleomycin sulphate To identify the transcriptional response of cells exposedto bleomycin sulphate,...
... with prostate cancer – were prospectively enrolled onto an intramural protocol Each underwent CT simulation in the supine position in an alpha cradle fixed to the treatment table in order to minimize ... received the intended total dose Treatment was never stopped because of toxicity Acute Grade toxicity was seen in 9% of patients Late Grade and Grade gastrointestinal toxicity was seen in patients ... A variety of strategies are being explored to quantify and address issues relating to pancreatic motion, including gating of radiation with respiration[4] and implantation of markers to directly...
... heterogeneous small interfering RNAs (siRNAs) As regulatory relationships are refined, the precision and phasing of hairpin processing may increase Shortening of the hairpin to produce a single defined duplex ... in plants, but one short hairpin intron in rice (MIR1429) generates specific miRNA/miRNA* reads indicative of mirtron processing [58] In addition to other types of Drosha-independent miRNAs in ... 1b), which are pre-miRNA hairpins whose ends are defined by splicing instead of Drosha cleavage [55-57] Following their debranching into a linear form, they are diced into conventional miRNAs Mirtron...