some ultrastructural changes in the brain of phenylketonuric rats and monkeys

... suggest that this hypothesis is true The decrease in the number of vacuoles stained in an intense purplish red colour as a result of the PAS reaction, and the increase in the number of yellow vacuoles ... 20th of January most of them stained red after the PAS reaction [Figs 2(8A) and 2(8B)] In the material collected on 28th of January the pith cells at the base of the embryonic shoot and some ... starch grains There were no changes during autumn and winter [11] In the present study starch in a spruce bud was found in the embryonic shoots during winter However, the starch grains were so...

Ngày tải lên: 08/08/2014, 01:21

... Although succinylacetone and CoCl2 are known inhibitors of heme biosynthesis, these agents also elicit nonspecific and toxic effects in animals To ascertain that the effects of these agents, on the catalytic ... 0.1% Chaps and 150 mM NaCl and protease inhibitors [5 lgÆmL)1 pepstatin A, lgÆmL)1 aprotinin, and mM phenylmethanesulfonyl fluoride]) and lysed by three cycles of freezing and thawing in liquid ... assayed in membrane fragments (SMP) by the method of Smith [20], wherein the rate of oxidation of ferrocytochrome c was measured by following the decrease in absorbency of its a band at 550 nm The...

Ngày tải lên: 20/02/2014, 23:20

... degenerate case of the NSI action In the case of the NSI action, the speaker and hearer mutually know of a plan that will result in identification of the intended referent, and in the case of the S[ action, ... along the horizontal axis of Figure There are really' two kinds of definite referring actions: one is that in which the precondition is mutual knowledge of a description and the other in which there ... possible There are several ways to measure the complexity of a description, including the number of descriptors involved and the ease with which these descriptors can be incorporated into the utterance...

Ngày tải lên: 21/02/2014, 20:20

Ngày tải lên: 16/03/2014, 09:20

Ngày tải lên: 23/03/2014, 10:21

... domain and also with the idea that binding of the PCP to the A domain in a productive manner increases the compactness of the protein Further control reactions with a noncognate inhibitor of the ... consisted of the first two functional domains, namely the phenylalaninespecific A domain and the PCP domain The terminal E domain was excised (the exact amino acid composition of the investigated protein ... propose the following model Binding of inhibitor induces the thioester conformation of the A domain, and the solventprotected Ppant thiol points simultaneously into the catalytic centre of the A...

Ngày tải lên: 29/03/2014, 08:20

... present in brain, but not in PBL (Fig 3A, lanes and 3) To examine whether the CbD4 variants were expressed in different parts of the brain as well as in fetal brain, PCR was carried out using the ... expressed in Rhesus monkey brain but probably not in mouse brain As depicted in Fig 6A, exon encodes an a-helix in the outer border of the catalytic domain in Ca1 (yellow line), suggesting that ... DC305863 and DC310086) and several of the CbD4 variants contained sequences encoded by the exons a, b and c in the Cb gene that are only transcribed in nerve cells [6] In addition, the brain is the...

Ngày tải lên: 30/03/2014, 04:20

... approach the company and the continuing owners Sometimes the company or the continuing owners will be happy to buy the departing owner out—perhaps the company is now quite profitable and the remaining ... purchase the interest of the transferring owner at the Agreement Price selected in Section VI and according to the manner of payments and other terms of the purchase as established in Section VII of ... conditions are met: • the power to revoke the trust remains with the grantor (the owner of the interest), and • the grantor (the owner of the interest) is a trustee of the trust If the owner ceases...

Ngày tải lên: 18/04/2014, 14:03

... about the utility of GSPT for explaining the dynamics of both the full and simplified versions of the model [31–33] For the values of the parameters used here, the right-hand sides of the c, n and ... involves the fast variables, all the information needed to determine the criticality of the bifurcation is contained in the fast subsystem but in other cases there is crucial information in the ... voltage attained on the corresponding branch of periodic orbits in the reduced model (b) An enlargement of part of (a), near the left pair of Hopf bifurcations On the other hand, in [29], the authors...

Ngày tải lên: 20/06/2014, 23:20

... completes our proof since the manipulations at the beginning of the section prove that the two quotients in (5.42) have the same Hilbert series References [1] Yu Berest, P Etingof and V Ginzburg, Cherednik ... where Sλ is the Schur function corresponding to λ, ST (λ) denotes the collection of standard tableaux of shape λ, co(T ) denotes the cocharge of T and cλ gives the sum of the contents of the partition ... lies in the ideal (p2 , gn )É[x,y] In particular, under the total order x > y we derive that x2 and y 2k lie in the upper set of leading monomials of the elements of this ideal It follows that the...

Ngày tải lên: 07/08/2014, 08:22

... feeding of the adults In the past two decades the grubs of M. hippocastani Fabr seriously hindered the regeneration of forest stands in some regions The results of evaluations of the abundance of ... the intensity of cockchafer swarming and interpreted the trend of development of the abundance of cockchafer tribes in the particular forest regions and then we estimated the assumed extent of ... out of the total number of adults of both species caught in the light trap were 34% in 2003, 84% in 2004, 81% in 2006, 68% in 2007 and 95% in 2008 On the basis of comparisons of the numbers of...

Ngày tải lên: 07/08/2014, 10:21

... For the plywood specimen inoculated with P ostreatus, the combination of resin coating and edge painting did not lead to a significant improvement in the level of protection than the resin coating ... resin coating and edge painting did not lead to a significant improvement in the level of mass loss than the resin coating alone Contrasting results were obtained in the test pieces inoculated ... testing protocol should give results in shorter times and be more in line with the real situations of the use of panels in outdoor conditions Within the current evolution of the European standardization...

Ngày tải lên: 08/08/2014, 01:21

... with the breaking of cambial dormancy (Little and Wareing, 1981Moreover, ABA content increases again in reactivating cambium, for example, in the trunk of Pinus contorta (Savidge and Wareing, ... peaking in late summer is rather incidental and drought-induced During winter, a decrease in the ABA level, often associated with an increase in conjugated ABA, is frequently reported, but these changes ... applied to the lower and upper sides of an inclined stem, respectively Reports concerning the intervention of other phytohormones in this process are somewhat conflicting Several observations indicate...

Ngày tải lên: 09/08/2014, 02:21

... existence of cells that contain both mucin and secretary granules within their cytoplasm Therefore we agree with the hypothesis of the dual entodermal and neuroendocrine origin of goblet cell carcinoid ... synaptophysin- and serotonin- (Figure 3) positive The endocrine cells in the appendix and caecum tumour samples were bombesin-, endorphin-, gastrin- and secretinnegative A combined histochemical and ... study the hormonal nature of goblet cell carcinoids, the location of hormones and the phenotype of endocrine cells Another useful method for simultaneous revealing of mucin secretion and endocrine...

Ngày tải lên: 09/08/2014, 07:21

... variance of the trait in the i th line is V and ; , the mean and the variance of the distribution of the variances of the lines are V and V(1; ), respectively In each line, the phenotypic variance ... variance between the lines, the variances of the phenotypic and additive variances of the lines will be the same and, therefore: where fl j CV(V and h are the coefficient of variation of the phenotypic ... selection The response to one generation of divergent selection in the i th line is R and the mean and the variance of the distribution of the responses ; , obtained in different independent lines...

Ngày tải lên: 09/08/2014, 22:22

... consequence of insulin therapy in diabetes altered the binding parameters of Muscarinic M1, M3 receptors and gene expression of α7nAchR, AchE, ChAT and GLUT3 in the cerebellum and AchE activity in the ... serotonin in the brain of diabetic rats and man Journal of Neurochemistry 1985, 44:94-98 22 Bitar M, Koulu M, Rapoport SI, Linnoila M: Diabetes induced alterations in brain monoamine metabolism in rats ... excitatory and inhibitory control over central and peripheral tissues In the present study, enhanced muscarinic M1 and M3 receptor binding in the cerebellum of insulin induced hypoglycemia in both...

Ngày tải lên: 10/08/2014, 05:21

... PiT1-binding immunoadhesin generated by fusing the aminoterminal residues of the GALV (SEATO strain) Env, comprising the signal peptide, the RBD and the proline-rich region, to the rFc tag, herein, ... transporters in the brain In conclusion, our data suggest that these new metabolic markers can be used to improve our understanding of the metabolism in the brain, as well as in others organs such as the ... abundance in the striatum, the thalamus and the brainstem [24] In mice, only blood vessels were found to be immunostained using an antibody raised against the C-terminal part of the protein [25,26]...

Ngày tải lên: 10/08/2014, 05:21

... wrote the first draft of the manuscript JJ, JC and JMA contributed to the final version of the manuscript GA, RB-D and AR helped in the data analysis and interpretation JJ and JC supervised the ... significant changes in the pattern of chemokine gene expression in circulating leukocytes The data suggest that PPARα activators may be useful in the attempt to decrease the risk of atherosclerosis and ... in HIV infection because it is the natural ligand for CXCR4 which is used by HIV Ttropic strains to enter into the cells in advanced stages of the disease [10] Additionally, although the interpretation...

Ngày tải lên: 10/08/2014, 05:21

... unchanging in all three varieties In leaves of the winter varieties, there was a decline in abundance between weeks five and nine – a 2.5-fold and 1.7fold decline, respectively, in Harnesk and Solstice ... developmental processes, and are thought to be involved in signaling, probably through the possession of a kinase domain residing within their C-terminal domain [13] Within the photoperiod pathway, ... levels of TaPHYA were initially much higher in the crown tissue of the two winter varieties than in Paragon and increased across the time course There was also an increase in transcript abundance in...

Ngày tải lên: 12/08/2014, 03:20

... Identification of Induced Protein Spots Given that recombinant XacPNP causes rapid and sustained physiological changes in the host, we were interested in investigating if these changes are also reflected in ... encodes a protein that contains only fractions of the reverse-transcriptase (RT) domain, and there is no evidence of the zinc-finger-like domain [36] However, MATK displays the domain X (the proposed ... photosynthetic parameters and the host proteome after short term exposure and discuss these findings in the light of plant-pathogen interactions We also discuss the possible cooperation of ABA and...

Ngày tải lên: 12/08/2014, 03:21