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Báo cáo khoa học: Molecular dynamics structures of peptide nucleic acidÆDNA hybrid in the wild-type and mutated alleles of Ki-ras proto-oncogene ppt
Ngày tải lên :
07/03/2014, 21:20
... mismatch in PNAÆDNA and DNA duplexes T Rathinavelan and N Yathindra Fig Interaction of water (orange) with A2 4 .C7 mismatch in PDwt (A L) and DDwt (M–T) during the dynamics Variation in hydration ... PNAÆDNA and DNA duplexes Intra strand base stacking at the AC(6–7) (Fig 2A) & CC(7–8) steps (Fig 2B) of the DNA strand, and GA(23–24) (Fig 2C) and AT(24–25) (Fig 2D) steps of the PNA strand, flanking ... different atoms of PNA chain Fig S3 Partial charges for the bases in: (A D) PNA and as given in Parm99.dat forcefield for a DNA chain (E–H) The following supplementary material is available online:...
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báo cáo hóa học:" Study of the collagen structure in the superficial zone and physiological state of articular cartilage using a 3D confocal imaging technique" pptx
Ngày tải lên :
20/06/2014, 01:20
... experiments, analyzing data and writing the manuscript TBK participated in initiating the idea cartilage and proof read the manuscript MHZ participated in design the experimental method and acknowledge of ... image using Alcian Blue staining was obtained to grade the physiological status of AC in terms of International Cartilage Research Society (ICRS) scores and understand the approximate concentration ... roughness of the AC surface shows the interwoven collagen network near the articular surface may play an important role in prevention of the initial lesion of AC surface and increase of the durability...
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báo cáo hóa học:" Substitutions in the Reverse Transcriptase and Protease Genes of HIV-1 Subtype B in Untreated Individuals and Patients Treated With Antiretroviral Drugs" potx
Ngày tải lên :
20/06/2014, 08:20
... synthesis of the negative strand of DNA can result in the insertion of a uracil as a result of the deamination of a cytosine, leading to the inclusion of an adenosine instead of guanosine in ... hypermutation may involve a cellular factor, APOBEC3G, a cytidine deaminase that converts cytosine to uracil The activity of APOBEC3G is inhibited by the Vif protein.[5,7,8] In the absence of Vif, the ... nucleotide substitutions in clinical samples in the RT and PR regions Results A 10-2 per nucleotide for the HIV-1 NY5 strain.[1-4] The rapid appearance of such mutations is, in part, a result of...
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Báo cáo nghiên cứu nông nghiệp " Marketing and Policy Analysis in the Post-Harvest and Resource Sectors of Vietnam " pot
Ngày tải lên :
22/06/2014, 13:20
... policy analysis and marketing skills so that Vietnam can rapidly become self-supporting in these areas and capable of providing training and the necessary skills to develop and teach appropriate ... relevant to the teaching and research needs and activities of the CARD project participants The emphasis on 'training the trainers' and networking was an efficient and sustainable way to establish ... expanded range and quality of material being taught In addition, the research capacity of a group of staff within the Ministry of Agriculture and Rural Development has been significantly increased...
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Báo cáo toán học: "ntersecting families in the alternating group and direct product of symmetric groups" potx
Ngày tải lên :
07/08/2014, 15:22
... half of these permutations are odd Now, interchange the entries containing the symbols n − and n in these odd permutations Together with the remaining even ones, they form a desired Latin square ... 1)! Again, the maximality of I implies that m = n and so I has the required shape as above Proof of Theorem 1.4 As before, the upper bound of |I| is given by the existence of Latin squares of ... Furthermore, if equality holds in (1), then for any independent set I of cardinality α(Γ ) in Γ2 , φ−1 (I) is an independent set of cardinality α(Γ1 ) in Γ1 Intersecting families in the alternating...
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Báo cáo y học: "Retention of foreign body in the gut can be a sign of congenital obstructive anomaly: a case report" potx
Ngày tải lên :
11/08/2014, 21:22
... [10,11]; an intramural width of small intestine of cm or less is considered abnormal An abdominal CT scan is of great help in diagnosing and detecting the etiology of intestinal obstruction in 73–95% ... increasing expertise, laparoscopy can be equally effective with all of the other advantages of a minimal access approach Hence, laparoscopy is now increasingly being employed for removal of ingested ... abdomen showing thebowel 'double Plain radiograph offew dilated loops ofpresence of ain the left Plain radiograph of the abdomen showing the metallic foreign body in the right lower quadrant, the presence...
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Báo cáo khoa học: ":Clinically important deep vein thrombosis in the intensive care unit: a survey of intensivists" pot
Ngày tải lên :
12/08/2014, 20:20
... Leo Pharmaceuticals, and additional grants for investigator initiated research from Pharmacia and Aventis Key messages Determining which DVT characteristics impart clinical significance to intensivists ... Strengths of the survey include comprehensive lists of both patient factors and ultrasonographic features that may influence clinicians' interpretation of the importance of a DVT in the ICU setting Ideally, ... (mean and standard deviation [SD]) Within each domain (patient factors and ultrasonographic features), we ranked the characteristics according to which were most likely to make the DVT clinically...
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Báo cáo y học: "An artificial intelligence tool to predict fluid requirement in the intensive care unit: a proof-of-concept study" docx
Ngày tải lên :
13/08/2014, 11:23
... pre-processing, and with the help of GA, the data analysis All authors read and approved the final manuscript Acknowledgements This work has been supported in part by National Library of Medicine Training ... to compare it against a p value The simplest relation between p values and Bayes factors are based on a Gaussian approximation In that situation, the Bayes factor is calculated with the same numbers ... physiological data from the previous 24 hours Materials and methods The Laboratory of Computational Physiology at Massachusetts Institute of Technology developed and maintains the Multi-parameter Intelligent...
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Báo cáo y học: "A prospective observational study of the relationship of critical illness associated hyperglycaemia in medical ICU patients and subsequent development of type 2 diabetes"
Ngày tải lên :
25/10/2012, 10:02
... involved in the analysis of results and writing the manuscript All the authors read and approved the final version Acknowledgements The authors are very grateful to Edita Lukić, Goran Madžarac and Alen ... according to the ACC/AHA criteria [26,27] Statistical analyses MedCalc™ v 9.6.2.0 (MedCalc Software, Mariakerke, Belgium) statistical software was used for all statistical analyses Categorical data ... participated in patients' inclusion and follow-up, performed statistical analyses, analyzed results and wrote the manuscript AVB and VG participated in patients' inclusion and follow-up IPR was involved...
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A study on oral presentation difficulties of second year english majors of phuong dong university in the speaking lessons and solutions
Ngày tải lên :
07/09/2013, 13:02
... unclear pronunciation, their bad voice quality, lack of confidence all made it difficult for them to be understood Besides, the data from the study confirm the fact that the infrequent and inadequate ... On the part of the second-year majors, for example, in order to be effective learners of English in general and effective speakers in particular, they need to improve their knowledge of the target ... University The survey questionnaire completed by the students was the main instrument employed for the collection of data The research reveals that the students’ low language proficiency including unclear...
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A study on oral presentation difficulties of second year english majors of phuong dong university in the speaking lessons and solutions
Ngày tải lên :
29/01/2014, 10:43
... relevance and importance of the study, as well as to clarify any questions that the learners had 2.3 Data Analysis and Discussion of the Findings 2.3.1 Data Analysis 20 In order to interprete the ... Once the learner has made an outline of the main points, write the presentation The main purpose of creating an outline is to develop a coherent plan of what the learner wants to talk about After ... care and enthusiasm, and they pay more attention to what they say as they are taking part in a kind of performance (it 40 is being recorded) and the results are surprisingly great Thirdly, videotaping...
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Tài liệu Mothers’ Investments in Child Health in the U.S. and U.K.: A Comparative Lens on the Immigrant ''Paradox'' docx
Ngày tải lên :
12/02/2014, 12:20
... Asia (India, Pakistan and Bangladesh), Africa and the Caribbean At the time of the 2001 Census, Indians were the largest minority group, followed by Pakistanis, Black Caribbeans, Black Africans ... from the Caribbean, Pakistan and Bangladesh have lower education and occupational qualifications than whites, on average, those from India, Africa and China have higher average qualifications ... years (age data are not yet available) These interviews and the baseline survey provide detailed information on the demographic, social and economic situations of the families and the health and...
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Tài liệu Báo cáo khóa học: Mutations in the hydrophobic core and in the protein–RNA interface affect the packing and stability of icosahedral viruses doc
Ngày tải lên :
19/02/2014, 12:20
... Structural and genetic analysis permit the identification of amino acid residues involved in the protein–RNA and protein–protein interactions that mediate these functions [9,31,32,39–42] Analysis of the ... thus interact with each other across the dimer interface Each also interacts with residues on the adjacent b-strand (F) and Ó FEBS 2003 with amino acids in the alpha-helical regions as they pass ... that Asp11 participates in both intra- and interchain interactions It appears to form a salt bridge to Lys113 on the alpha-helix of the adjacent subunit of the dimer, and may thus help to stabilize...
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Tài liệu Báo cáo khoa học: A possible role of mitochondria in the apoptotic-like programmed nuclear death of Tetrahymena thermophila Takashi Kobayashi and Hiroshi Endoh docx
Ngày tải lên :
20/02/2014, 03:20
... higher in fractions and than in fraction (Table 1) These results indicate that fraction contains a significant number of mitochondria, and that fraction is the main lysosomal fraction The DNAcleavage ... by Lu and Wolfe [23], who used a combination strategy of 4,6-diamino-2-phenylindole (DAPI) staining for the detection of DNA and Azo dye staining for the identification of acid phosphatase activity, ... cells and incubated with a circular plasmid as the substrate DNA The substrate plasmid DNA was 5381 Mitochondria in nuclear death of Tetrahymena T Kobayashi and H Endoh B A C Fig Mitochondrial nuclease...
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Tài liệu Báo cáo khoa học: Inorganic pyrophosphatase in the roundworm Ascaris and its role in the development and molting process of the larval stage parasites doc
Ngày tải lên :
20/02/2014, 11:20
... containing an XhoI (Promega) site upstream of the start codon and an antisense primer (5¢-CAGCCAA GCTTCTCACTCTTTGATGAAATGCATCT-3¢) containing a HindIII (Promega) site just downstream of amino acid ... to the calculated mass of the AdR44 cDNA (data not shown) The functional activity of the purified rAsPPase was determined using a PPi hydrolysis assay in a standard reaction mixture containing ... slaughterhouse in Shimotsuma, Japan Adult A lumbricoides and T canis were obtained from patients after treatment with piperazine in Bac Gian, Vietnam and, from an infected dog in Miyazaki, Japan, respectively...
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Tài liệu Báo cáo Y học: Structure of the O-polysaccharide and classification of Proteus mirabilis strain G1 in Proteus serogroup O3 potx
Ngày tải lên :
21/02/2014, 15:20
... analysis of the polysaccharide after acid hydrolysis revealed glucuronic acid (GlcA) and galacturonic acid (GalA) in the ratio : Analysis on an amino-acid analyser showed the presence of 2-amino-2-deoxygalactose ... tetrasaccharide repeating unit containing one residue each of D-GlcA and D-GalA, two residues of D-GalNAc, and L-lysine A smaller than expected relative content of GlcA in the polysaccharide hydrolysate could ... of a- D-GalpA6(L-Lys) in the O-chain polysaccharide [21] (Fig 3) and b-D-GalpA6(L-Lys) in the core oligosaccharide [29] No GalA6Lys is present in the polysaccharide chain (T-antigen) of P mirabilis...
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Tài liệu The Development of the Feeling for Nature in the Middle Ages and Modern Times doc
Ngày tải lên :
21/02/2014, 20:20
... landscape as a whole, and distance, light and shade in wood and water, reflections, the charms of hunting and rowing, day-dreams on a mountain side, and so forth That antiquity and the Middle Ages had ... place Nature's sympathy with human joys and griefs was taken for granted, and she played a part of her own in drama In the _Mahõbhõrata_, when Damajanti is wandering in search of her lost Nala ... contemplative side of Hindoo character, and the drama and historical plays came in, generalities gave way to definite localizing, and in the Epics ornate descriptions of actual landscape took independent...
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Báo cáo khoa họcRe-engineering the discrimination between the oxidized coenzymes NAD+ and NADP+ in clostridial glutamate dehydrogenase and a thorough reappraisal of the coenzyme specificity of the wild-type enzyme docx
Ngày tải lên :
06/03/2014, 00:20
... NADP+ can arise If we assume the use of a commercial NADP+ containing 0.3% NAD+, as in the case of the Roche sample used in this study, then in a steady-state assay, as in the rapid-reaction ... nicotinamide ring, suggesting that the covalent bond between the nicotinamide and the ribose of the coenzyme is particularly labile The signal of the parental molecule is also visible at m z 664. 1 ... study, the contaminating NAD+ will be used rst There will not be simple proportionality because the mm NAD+ in a standard assay is well above Km and the 0.3% NAD+ contamination in mm NADP+ is far...
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