setting the stage for thrombotic events

... of these genes in CM biology is being further examined either by gene transfer or RNA interference approaches in CM cell lines [21] The direct evaluation of the DNA methylation status of the ... [21]), which might contribute, together with the impairment of the apoptotic pathways, to the well-known resistance of CM cells to conventional chemotherapy The list of genes hypermethylated in ... [72] and zebularine To exert their activity, nucleoside inhibitors must be incorporated into the genomic DNA of the target cell during the S-phase of the cell cycle Their methylation by DNMT results...

Ngày tải lên: 18/06/2014, 16:20

... growth? The first theory I will advance is that as the earth’s population ages there is significantly more to celebrate and events provide the forum for these celebrations For example, during the ... 1996 Another potential role for the framework is to guide the preparation of questionnaires and other survey instruments used to gather the expenditure data which form the crucial input into the ... 36 Events Beyond 2000 assessment of events (and conventions) (Dwyer et al 1999a,b) GENERATING THE FORECASTING REPORT A forecasting model is the main output of the program The inputs to the forecasting...

Ngày tải lên: 16/03/2014, 11:20

... delivery setting, and here we compare the different criteria for determining ART eligibility Methods The study was based at The AIDS Support Organisation (TASO) clinic in Jinja, SE Uganda The setting ... study used physicians to stage patients, working in a research setting The accuracy of the WHO clinical stage criteria are unknown in a normal health service delivery setting, where training and ... and stored at the trial site within hours of collection They were transported to the laboratory and tested using the HIV-1 RNA 3.0 Assay (bDNA) (Bayer AG) The study was approved by the ethics committees...

Ngày tải lên: 10/08/2014, 05:21

... factors Furthermore, at this stage, the main task of the flower bud is to complete the growth and maturation of anthers and the pistil Consequently, the intensity of the signalling events in the stigma ... peaks for Ca and Sb The strong decrease of the Ca2+ pool in the pistil at the last stages of pistil development coincides with the degradation of the stigma tissues The decay of the stigma is the ... During flower anthesis (from stage to stage 4), the Ca 2+ pool increased progressively and reached the maximal values just after anther dehiscence (stage 4) At the latest analyzed stage (stage 5) a...

Ngày tải lên: 11/08/2014, 11:21

... survival of the patients [3] Little is known about the complex interactions taking place within the human lung upon chemotherapy One reason for this might be implied by the common models used for analyzing ... responsible for the surgical part of the investigation CM and ARR carried out the LIFE/DEAD-assay and 2-photon microscopy PZ was involved in the design of the study, evaluation of the results ... covered the clinical part EV was involved in the design of the study and histomorphological evaluation TG conceived the study and was involved in the evaluation of the data as well as the writing...

Ngày tải lên: 12/08/2014, 15:20

... analysis of the performance matrix The performance matrix may be the final product of the analysis, allowing the decision maker to qualitatively rank the options Such intuitive processing of the data ... how the basic information in the performance matrix can be processed – either qualitatively or quantitatively http://www.resource-allocation.com/content/4/1/14 The performance matrix In a performance ... representing preferences for the consequences, to weight the scales for their relative importance, and then to calculate weighted averages across the preference scales [42] First, the expected consequences...

Ngày tải lên: 13/08/2014, 11:22

... is the sponsor for the study The other authors declare that they have no competing interests Authors' contributions SDS managed day-to-day activities of the study and wrote the majority of the ... were asked to clarify if the patients had other re-hospitalizations for dyspnoea or edema or deaths for cardiovascular events On the basis of the BNP absolute value at the moment of discharge, ... was utilized to test for the significance of the two BNP indicators (discharge and percentage change) simultaneously and to test for the interaction of these two predictors For all comparisons,...

Ngày tải lên: 13/08/2014, 20:22

Ngày tải lên: 27/03/2015, 14:43

... motivation At the level of the individual cow, the veterinarians seemed to base their treatment decisions on the cow's characteristics They focussed generally on the practical use of the score to ... on the farm level Such veterinarians are motivated to collect valid data at the herd level They perceive the collection of the data in and of itself as the basis for taking relevant action at the ... and the individual veterinarians' perceptions expressed in their local context Our basis for the model is thus the empirical data and not an initiating general theory or hypothesis From these...

Ngày tải lên: 25/10/2012, 10:45

... distribution, to the information provided to the prescribers and the patients It is the sum total of the organized arrangements made with the objective of ensuring that medicinal products are of the quality ... WHO Therefore, it is more useful to introduce briefly about the other famous and former GMP such as WHO GMP, U.S GMP before mentioning ASEAN GMP 2.2.1 Introduction of other GMPs • WHO GMP: The ... ensure the delivery of equipment or the design of the facilities in accordance with the requirements of the code of GMP This may require the education of suppliers to allow them to meet these...

Ngày tải lên: 06/11/2012, 10:26

... success On the 12th of July following it was acted at Vaux, the country seat of Fouquet, before the whole court, Monsieur, the brother of the King, and the Queen of England; and by them also was ... by the mouth of Ariste: for The School for Husbands was performed on the 24th of June, 1661, and about eight months later, on the 20th of February, 1662, he married Armande Béjart, being then ... Molière's The School for Husbands Murphy, in The School for Guardians, has borrowed from three plays of Molière The main plot is taken from The School for Wives; some incidents of the second...

Ngày tải lên: 06/11/2012, 14:13

... share exactly the same information If the task is correctly set, the students must pool their information and are thus forced to communicate through English The information gap is therefore an important ... This stage is to prepare the students for what they are going to hear The teacher should not just tell the students to listen and then start the cassette While-listening: This stage is to help the ... filled in to guide their listening Students listen and fill in the rest in note form Example: Listen to the weather forecast and fill in the blanks with the information in the text (TIÊNG ANH...

Ngày tải lên: 07/11/2012, 14:41

... NATIONAL UNIVERSITY, HANOI COLLEGE OF FOREIGN LANGUAGES POST GRADUATE STUDIES DEPARTMENT TRẦN QUỐC VIỆT A STUDY ON THE TECHNIQUES FOR THE IMPROVEMENT TO THE TEACHING OF ORAL SKILLS IN LIGHT OF ... COMMUNICATIVE ENGLISH LANGUAGE TEACHING FOR JUNIOR HIGH SCHOOL TEACHERS IN QUẢNG NGÃI PROVINCE (NGHIÊN CỨU CÁC THỦ THUẬT NÂNG CAO VIỆC DẠY KỸ NĂNG NGHE NÓI TIẾNG ANH THEO ĐƯỜNG HƯỚNG GIAO TIẾP CHO GIÁO ... NÓI TIẾNG ANH THEO ĐƯỜNG HƯỚNG GIAO TIẾP CHO GIÁO VIÊN TRUNG HỌC CƠ SỞ TẠI TỈNH QUẢNG NGÃI) M.A.THESIS HA NOI-2007 ...

Ngày tải lên: 07/11/2012, 14:41

... College of Foreign Languages, Vietnam National University-Hanoi for their valuable lectures And their knowledge, their thoughtfulness as well as their sympathy I will always appreciate For the accomplishment ... Tiến and the staff members of Postgraduate Department, College of Foreign Languages, VNU-Hanoi for their enthusiastic support I am sincerely grateful to Mr Đinh Tấn Bảo and my colleagues of Foreign ... Teachers Training College for their attention and encouragement I am appreciative of all those who have kindly advised and helped me during the period of my study at College of Foreign Languages, VNU-Hanoi...

Ngày tải lên: 07/11/2012, 14:41

... skill Secondly, the questions in the questionnaires and the interviews may not cover all the important information for the study Moreover, the answers of the teachers and students to the questionnaires ... One interview is for teachers who had finished their teaching of speaking lessons observed by the researcher; the other is for students from the observed classes The interview for teachers consists ... learn these two skills most When the researcher asks them whether they are satisfied with their recent English speaking skill (Question 3), all of them but one respond that they are not because their...

Ngày tải lên: 07/11/2012, 14:44

... 32% the same as the position in Hong Kong in 1980 The figure is expected to rise to 75% by the end of the nineties, less than half the time it took in Hong Kong In the Philippines, despite the ... explain their frequency density to go there We can say that the heavy-users have confirmed the real need for supermarkets’ existence If the stores could explore the appropriate ways to turn up the ... into supermarkets, while the heavy ones go there mainly for buying everyday necessities, for what the core business of the stores offer 4.2 From the supermarket side The booming economy during...

Ngày tải lên: 13/04/2013, 10:30

... using the results from the first simulator to model the lower layers The simulations are used to validate the performance of the designed networking algorithms, to optimize and fine-tune the relevant ... network to realize the vision of “Networking the Sky” To realize the vision of “Networking the Sky”, the following five main objectives that reflect the working program of the project have been ... performed leading to the definition of the NEWSKY network concept This goal is achieved by splitting this task into the design and definition of the network architecture on the one side and the...

Ngày tải lên: 05/09/2013, 11:07

... important role in the development of Mechanical Engineering The thesis studies the English – Vietnamese translation of terms in the materials for Mechanical Engineering First, the thesis collects ... Vietnamese ones Next, the thesis works out and compares the English terms with the Vietnamese ones to finds out appropriate Vietnamese equivalents for the English terms The thesis aims to draw ... translation strategies which can be applied in the English-Vietnamese translation of terms in materials for mechanical engineering Hopefully, the result of the study would be useful in technical translation...

Ngày tải lên: 07/09/2013, 13:04

... share exactly the same information If the task is correctly set, the students must pool their information and are thus forced to communicate through English The information gap is therefore an important ... better than the ENGLISH textbook series They like the clear layout, the variety of exercise types and the logical sequencing of the TIENG ANH textbook series However, they want to reduce the number ... of the advantages offered and to minimize the shortcomings revealed Also in the first chapter are the definition and principles of the communicative approach Last in the first chapter are the...

Ngày tải lên: 07/09/2013, 13:06