... values of 0.09 and 0.18 for hSGLT1 and hSGLT2, respectively These data clearly show the electrogenic uptake of thioglycoside I and VII across the plasma membrane Discussion Figure Correlation of ... membrane potential induced by D-glucose, thioglycosides I and VII and phlorizin As expected, the maximal effect was observed with D-glucose with FRET values of 5.62 and 2.29 for hSGLT1 and hSGLT2, ... therapies and emerging targets for the treatment of diabetes Current Pharmaceutical Design 2001; 7: 417-450 Wood IS, and Trayhurn P Glucose transporters (GLUT and SGLT): expanded families of sugar...
Ngày tải lên: 26/10/2012, 10:04
... viability of HT-29 and LS-174T cells …………………………………………63 Figure 3.2 Effect of fixed ratio combinations of safingol and irinotecan in HT-29 and LS-174T cells ………………………………………66 Figure 3.3 Effect of safingol, ... Biological sources and anti-oxidant defense mechanism of ROS 25 1.3.2 ROS and cancer 27 1.3.2.1 ROS and cell survival 28 1.3.2.2 ROS and cell death .29 1.4 Overview of sphingolipids ... Effect of fixed ratio combinations of safingol and irinotecan 65 3.2.3 Effect of safingol/irinotecan at 1:1 molar ratio on the cell cycle status of colon cancer cells .68 3.2.4 Role of PKC...
Ngày tải lên: 11/09/2015, 10:02
Separation of organic and biomolecules using nano sized magnetic particles
... application of nanosized magnetic particles in the separation of organics and biochemical molecules, and the evaluation of the effectiveness of the separation method The desired goals of different ... Magnetic Separation for Binary Mixture of BSA and LSZ 95 6.1 Introduction 95 6.2 Results and Discussion 97 6.2.1 Selective Adsorption of BSA and LSZ 97 6.2.2 Sequential Adsorption of BSA and LSZ ... UV-scanning spectra of native lysozyme (pH 4.0 and pH 6.0) and desorbed lysozyme by NaH2PO4 and NaSCN 88 Figure 5-5 Comparison of CD spectra of native lysozyme (pH 4.0 and pH 6.0), and desorbed lysozyme...
Ngày tải lên: 16/09/2015, 17:11
Báo cáo y học: "Characterization of N200 and P300: Selected Studies of the Event-Related Potential Salil H. Patel 1 and Pierre N. Azzam 2"
... Shappell SA, Brandt ME Psychophysiology of N200/N400: A review and classification scheme Advances in Psychophysiology 1991; 4:43-106 Hoffman JE Event-related potentials and automatic and controlled ... relationship of age, gender, handedness, and sidedness to the size of the corpus callosum Academic Radiology 1994; 1:243-248 69 Driesen NR, Raz N The influence of sex, age, and handedness on ... between age and callosal size Conversely, a subsequent review of MRI and post-mortem reports indicated a callossal volume relationship to handedness and gender [69]; the clinical significance of these...
Ngày tải lên: 02/11/2012, 11:08
Potential biogas production from sewage sludge: A case study of the sewage treatment plant at Kwame Nkrumah university of science and technology, Ghana
... estimation of the biogas potential of the sludge the quality of the sludge was analysed and the results is presented below in Table The average litre of biogas produced from a kg of TVS found ... Journal of Energy and Environment (IJEE), Volume 1, Issue 6, 2010, pp.1009-1016 1011 Kwame Nkrumah University of science and technology (KNUST) generates a colossal amount of waste (solid and liquid) ... and policy, and CDM proposal development He is also an associate of The Energy Centre, KNUST and a founding member of a not-for-profit organization; Centre for Energy, Environment and Sustainable...
Ngày tải lên: 05/09/2013, 16:11
Biochemical characterization of thermophilic lignocellulose degrading enzymes and their potential for biomass bioprocessing
... During extrusion, a screw speed of the extruder of 100 rpm and a barrel temperature of 100°C was maintained [28] 2.3 Sample collection Samples of yard waste compost (YWC) and finished yard waste compost ... (filer paper), BWX and PWSD The enzyme kinetic studies for cellulase and xylanase (Km and Vmax) were performed with 1-10 mg/ml of CMC and BWX, respectively [35] The crude cellulase and xylanase were ... albumin as standard [38] All experiments were run in duplicate and standard deviations (SD) were calculated using Microsoft Excel and results were presented as average ± SD Results and discussion...
Ngày tải lên: 05/09/2013, 16:11
Tài liệu Male Reproductive Health Disorders and the Potential Role of Exposure to Environmental Chemicals pdf
... some of the weaknesses and problems that can affect the quality of studies investigating the potential causes of cryptorchidism and hypospadias Quality assessment of the various studies and of ... prevalence, and evidence for changing incidence, of human TDS disorders; and (2) the range of TDS-like effects of ECs and EC mixtures in animal studies, together with new understanding about when and ... father’s nose; Sperm and egg; Baby’s face; Father and son at sunset [Andrew Penner]; all courtesy of [©iStockphoto.com] Male Reproductive Health Disorders and the Potential Role of Environmental...
Ngày tải lên: 13/02/2014, 10:20
Tài liệu Medicinal Chemistry and Pharmacological Potential of Fullerenes and Carbon Nanotubes docx
... considered both one of the most promising applications and one of the most studied since the publication of the fundamental works of Dugan and coworkers, who analyzed fullerene capability of scavenging ... with diameters in the range of 0.5–1.5 nm and 2–100 nm and lengths in the range of 20–1,000 nm, and 1–50 μm for SWNTs and MWNTs, respectively 2 Biomedical Applications of Functionalised Carbon ... metallic and semiconducting SWNTs in a mixture of one third and two thirds, respectively Bundle properties are generally inferior to those of isolated SWNTs and effective separation of aggregates...
Ngày tải lên: 17/02/2014, 05:20
the method of investment appraisal which may be applied to evaluated and rank potential investment opportunities and their relative merits and limitations
... opportunities and their merits and limitation Moreover, the nature of gearing and potential effected of high gearing on perceived risk and cost of capital I-Analysis of the reasons behind takeovers and ... not reliable NPV must be used for this type of project III- The nature of gearing and the potential effects of high gearing on perceived risk and cost of capital 11 There are some ways to increase ... corporate gearing Two of these, the advantage of debt being ‘cheaper’ than equity and the disadvantage of the cost of equity rising because of increase financial risk, exactly offset each other This...
Ngày tải lên: 17/02/2014, 13:02
Tài liệu PHYSICAL, CHEMICAL, AND MECHANICAL PROPERTIES OF BAMBOO AND ITS UTILIZATION POTENTIAL FOR FIBERBOARD MANUFACTURING docx
... longitudinal and radial directions of one, three, and five year old bamboo and determine the correlation between SG and bending properties, and (5) compressive strength of bamboo at different ages and ... modulus of rupture, modulus of elasticity, and compressive strength To fabricate bamboo fiberboard and evaluate water soaking, modulus of elasticity (MOE), modulus of rupture (MOR), and internal ... [Leithoff and Peek 2001] Since the amount of each chemical composition of bamboo varies with age, height, and layer, the chemical compositions of bamboo are correlated with its physical and mechanical...
Ngày tải lên: 22/02/2014, 09:20
Báo cáo khoa học: Ubiquitination of E3 ubiquitin ligase TRIM5a and its potential role pdf
... Ubiquitination of TRIM5a and its role K Yamauchi et al the evolutionary distance of TRIM5a is very close to that of Ro52, TRIM6, and TRIM34, suggesting that TRIM proteins such as Ro52, TRIM5a, TRIM6 and ... Ubiquitination of TRIM5a and its role K Yamauchi et al A B Fig E3 activity of wild-type TRIM5a and its RING mutant in vitro (A) Schematic representation of the RING-finger domain of TRIM5a The ... Ubiquitination of TRIM5a and its role (Fig 7, lane 5) In contrast, the coexpression of Ro52 and ubiquitin with UnpEL(C311A) did not affect the ubiquitination of Ro52 (Fig 7, lane 6), because of the substitution...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: Critical roles of Leu99 and Leu115 at the heme distal side in auto-oxidation and the redox potential of a hemeregulated phosphodiesterase from Escherichia coli pptx
... ligand binding kinetics of the PAS domain of Ec DOS, as it does in myoglobin and hemoglobin Examination of the effects of these hydrophobic amino acids on the kinetics of O2 and CO binding to the ... the rate of auto-oxidation and the redox potential of the heme iron, but, surprisingly, they had less effect on the characteristics of O2 and CO binding Finally, we discuss the roles of these ... direction of the heme-bound O2 molecule, and the redox potential of the heme iron [5] The reason why the auto-oxidation rate of the Leu99 and Leu115 mutants was much higher than that of the wild-type...
Ngày tải lên: 16/03/2014, 13:20
Detection of actual and assessment of potential plantations in Lao PDR using GIS and remote sensing technologies doc
... plantations, and already many of the smallholders rely on prospects of future sales of latex and thus depend on the dynamics of the global market The success story of Yunnan and the high demand of China ... 3.1.3 Analysis of land use and land cover changes 3.2 25 34 A spatial assessment of the potential development of rubber plantations in Laos 51 3.2.1 Reasons for the necessity of potential rubber ... an impression of the landscape and land cover, land use practices, distribution of settlements, etc With the collection of GPS points the classification of the satellite imagery and its verification...
Ngày tải lên: 17/03/2014, 11:20
Báo cáo khoa học: Association of RNA with the uracil-DNA-degrading factor has major conformational effects and is potentially involved in protein folding pot
... suggest the potential existence of two separate conformational states of the protein, one of these containing a signicant amount of associated nucleic acid To address the potential signicance of these ... the RNA-UDE state of Fig 5A, where the secondary structural elements termed Helix1, Helix2, Strand1 and Strand2 correspond to the two subcategories of helices and sheets (regular and distorted fractions) ... double-stranded cDNA, using both random hexamer and oligo-dT primers in independent experiments, randomly cloned, and 22 and 11 positive colonies, respectively, were sequenced Both UDE mRNA and 23S...
Ngày tải lên: 22/03/2014, 16:21
Internal Audit 2012*: A study examining the future of internal auditing and the potential decline of a controls-centric approach docx
... provide all of the necessary skills and expertise • Solid understanding of measures intended to prevent and detect fraud • Awareness of financial fraud schemes and scenarios and knowledge of forensic ... internationalization of accounting standards may lead to a change in the language of accounting • The growth of outsourcing and an upsurge in the offshoring of services and manufacturing have ... auditing operations are often piecemeal and fall short of facilitating the type of strategic change required to satisfy stakeholder demands for more timely and continuous assurance and risk assessment...
Ngày tải lên: 23/03/2014, 04:20
Báo cáo khoa học: Gene duplication and separation of functions in aB-crystallin from zebrafish (Danio rerio) pptx
... three clusters of cDNAs for members of the a-crystallin family From a total of about 3700 sequences, 63 corresponded to aA-crystallin and 24 to aB-crystallin However, a third group of 28 clones ... Fig SDS ⁄ PAGE analysis of native zebrafish lens and various recombinant proteins Four micrograms of total soluble zebrafish lens protein (zebrafish) and one microgram each of recombinant zebrafish ... retinoic acid-binding proteins [23] Separation of functions after gene duplication also occurred during evolution of d-crystallin, a major component of the bird and reptile lens, from the enzyme...
Ngày tải lên: 30/03/2014, 11:20
Báo cáo khoa học: Characterization of depolarization and repolarization phases of mitochondrial membrane potential fluctuations induced by tetramethylrhodamine methyl ester photoactivation pdf
... occurrence of mitochondrial swelling, a marker of permeability transition The duration of D and R phases was 1.05 and 0.77 s, respectively The rate of fluorescence changes in D and R phases was 15 and ... illumination and sampled at the rate of one image every 60 ms Typical MMPFs are evident, but the separation of D and R phases is imprecise (C) Derivative curve of the TMRM trace R and D phases ... peaks, irrespective of the tail direction The value of 0.333 was set as cut-off for symmetry The relative frequency of rejections because of height, width and symmetry was 78%, 16% and 6%, respectively...
Ngày tải lên: 30/03/2014, 16:20
Separation of acetic acid and water by distillation effect of calcium chloride addition
... nature of the salt; amount of salt; pH of the solution from which the salt is applied; solvent for the cellulose acetate in solution; degree of hydrolysis of cellulose acetate; and the amounts of ... 140.0 because of the lack of available data on the boiling points of solutions of calcium chloride in glacial acetic acid CONCLUSIONS The results confirm the observation of Quartaroli (9) ... measure of the increase in viscosity of cellulose acetate caused by the presence of certain salts A procedure for the measurement of the salt effect has been developed The influence of salts...
Ngày tải lên: 05/05/2014, 08:42
Separation of the tax and audit function Motivation and consequences
... economically feasible reasons for separation of the tax and audit function The primary research question focuses on the motivations and consequences of separation of the tax and audit functions This study ... firms and audited companies Section discusses auditor independence and capital market visibility as motivations, and audit quality as a motivation and a consequence of the separation of the tax and ... separation sample: (1) in 2002 and 2003, separation companies’ audit fees decreased and audit quality decreased; and, (2) in 2004 management lowered its ownership stake and analyst coverage and...
Ngày tải lên: 01/06/2014, 14:03