separating graft versus leukemia effect from graft versus host disease

... supportive care of chronic graft- versus- host disease: National Institutes of Health con­ sensus development project on criteria for clinical trials in chronic graft- versus- host disease: V Ancillary ... graft- versus- host dis­ ease: I Diagnosis and staging working group report Biology of Blood and Marrow Transplantation, 11, 945-956 Higman, M A., & Vogelsang, G B (2004) Chronic graft versus host ... Blood and Marrow Transplantation Working Party Chronic Leukemia (1995) Graft- versus- leukemia effect of donor lymphocyte transfusions in marrow grafted patients Blood, 86, 2041-2050 Kondo, M., Kojima,...

Ngày tải lên: 12/02/2014, 19:20

... graft- versus- host disease Stem Cells 1996, 14:473-489 29 Chan GW, Gorgun G, Miller KB, Foss FM: Persistence of host dendritic cells after transplantation is associated with graftversus -host disease ... bone marrow from mice undergoing a graft- vs -host reaction J Immunol 1986, 137:3100-3108 Via CS, Finkelman FD: Critical role of interleukin-2 in the development of acute graft- versus- host disease ... chronic graft- versushost reaction J Immunol 1993, 150:361-366 20 Garlisi CG, Pennline KJ, Smith SR, Siegel MI, Umland SP: Cytokine gene expression in mice undergoing chronic graftversus -host disease...

Ngày tải lên: 09/08/2014, 08:22

... BJ, Cui X, Liu C and Chao NJ 2002 Prevention of graft- versus- host disease while preserving graft- versus- leukemia effect after selective depletion of host- reactive T cells by photodynamic cell purging ... of acute graft- versus- host disease Immunology 98: 379-385 Hu HZ, New JY, Li B, Chan SH, Yap EH 2000 Depletion of activated alloreactive T cells in prevention of acute graft- versus- host disease ... for Graft- vs -host disease J Exp Med 196: 401-406 Cohen JL, Trenado A, Vasey D, Klatzmann D, Salomon BL 2002 CD4(+)CD25(+) immunoregulatory T Cells: new therapeutics for graft- versus- host disease...

Ngày tải lên: 16/09/2015, 17:13

... Nowell, 1970) This vigorous response results in quick rejection of allografted organs and cells, or acute graft- versus- host disease (GVHD) in recipients of bone marrow transplantation (BMT) (Hayry, ... immunocompetent donor T cells present in the allogeneic bone marrow graft, total T cell depletion from the graft often results in engraftment failure, leukemia relapse, immunodeficiency and viral infection ... our preliminary experiment using Percoll for separating proliferating from non-proliferating cells, we had already observed that the cells isolated from the lower density fraction (contained mostly...

Ngày tải lên: 16/09/2015, 17:13

... controls (open circle) 86 _ Results 3.1.5 Conclusions Acute graft- versus- host disease (GVHD) involves mainly skin, liver, and intestines Other organs such as heart, ... heart, in acute GVHD 87 _ Results 3.2 Induction of Acute Graft- versus- host Disease by T Cells that Do Not Respond to In Vitro Alloantigenic Stimulation Although other ... Depletion of T cells from the allograft reduces the risk of GVHD (Frame et al., 1989), but the rate of graft rejection is increased for patients with malignancy; the risk of disease relapse is...

Ngày tải lên: 16/09/2015, 17:13

... considered to reliably reflect the degree and severity of GVHD Table Criteria of acute graft- versus- host disease in mice Criteria Weight Loss Posture Grade

Ngày tải lên: 16/09/2015, 17:13

... of T-cell–depleted grafts, demonstrating the importance of donor mature T-cell–provided graft- versus- leukemia (GVL) effect (Kernan, 1994) GVL effect may be mediated by both host histocompatibility ... competent cells in the graft, the host appearing “foreign” to the graft, and the inability of the host to react sufficiently against the graft The interaction of donor cells and host target tissues ... _ Literature Survey 1.2 Graft- vs -host disease 1.2.1 Introduction Graft- vs -host disease (GVHD) is a complex condition that can occur after allogeneic...

Ngày tải lên: 16/09/2015, 17:13

... per the Government Order issued from time to time in this regard OMB 3.4 All graduates other than the graduates of VTU shall have to obtain Eligibility Certificate from the VTU to seek MBA admissions ... 8.4 OMB 8.3 There shall be no restriction for promotion of a candidate from the first semester to the second semester and from the third semester to the fourth semester provided he/she has fulfilled ... candidate who has not failed in more than four heads of passing from the first and second semester put together shall be eligible for promotion from the second semester to the third semester OMB AWARD...

Ngày tải lên: 18/02/2014, 08:20

Ngày tải lên: 11/03/2014, 16:20

Ngày tải lên: 09/08/2014, 01:21

... specific time period without the use of disease modifying antirheumatic drugs In the disease state with low disease activity’ definition of remission, treatment with disease modifying antirheumatic ... measurement disease progression can occur [29] The most likely explanation for this observation is that either subclinical disease is present or the waxing and waning disease activity of a low disease ... patients with ‘drug-requiring low disease activity’, we propose the wording disease state with low disease activity’ for this patient group Risk factors for a state of low disease activity in rheumatoid...

Ngày tải lên: 09/08/2014, 08:22

... attributable to refugees versus host nationals The proportion of new outpatient visits to settlement health facilities attributable to refugees is higher than that attributable to host nationals In ... Proportion of New Outpatient Department Visits per Month by Refugees vs Host Nationals, 2008-2009 Refugee Host National Ref - Host Difference p Value* Region/Country/Camp Pct * 95% CI* Pct * 95% ... Outpatient Department Visits by Females, Refugee vs Host Country Patients, 2008-2009 All Region/Country/Camp Refugee Host Pct OPD Female Ref - Host Difference p Value* Percent OPD Visits Female*...

Ngày tải lên: 13/08/2014, 15:21

... EFFECT FROM DOPING OF QUANTUM WELLS 25 We find that for roughness-related scattering from two interfaces or from the dopingside interface, the mobility ... roughness scattering II ONE-SIDE AND TWO-SIDE DOPED SQUARE QW To start with, we examine the effect from doping-induced band bending on the carrier distribution along the growth direction For ... scattering potential associated with the top interface (z = −L/2) is given as follows for electrons: EFFECT FROM DOPING OF QUANTUM WELLS 27 [21] We may obtain the ACFs for misfit DP scattering for holes...

Ngày tải lên: 30/10/2015, 19:39

... chronic kidney disease Am J Epidemiol In press Abraham AG, Munoz A, Furth SL, Warady BA, Schwartz GJ: ˜ Extracellular volume and disease progression in children with chronic kidney disease Clin ... Warady BA, Furth SL: Hemoglobin decline in children with chronic kidney disease: Baseline results from the chronic kidney disease in children prospective cohort study Clin J Am Soc Nephrol 3: 457– ... Parekh SR, Furth SL, Warady BA: Blood pressure in children with chronic kidney disease A report from the Chronic Kidney Disease in Children Study Hypertension 52: 631– 637, 2008 Mitsnefes M, Ho PL,...

Ngày tải lên: 05/03/2014, 12:20

... the Editor of RNA Interference: From Basic Science to Drug Development (2005) To my wife Shyamala for her 25 years companionship MicroRNAs FROM BASIC SCIENCE TO DISEASE BIOLOGY Edited by Krishnarao ... in development and human disease The full scope of the involvement of microRNAs in human disease is difficult to envision at this early stage, but it is already clear from the work reported here ... professors from academic research institutions who wish to initiate microRNA research in their own laboratories Additionally, this book will serve MicroRNAs: From Basic Science to Disease Biology,...

Ngày tải lên: 06/03/2014, 09:21

... diseases: asthma/COPD) was confirmed by cardiologists and/or intensive care physicians in the University Clinical Center Maribor using the reference standard definition for HF and pulmonary diseases ... myocardial infarction Point value: no more than points allowed from each of three categories; hence the composite score (sum of the subtotal from each category) has a possible maximum of 12 points The ... excluded from the study The clinical and demographic characteristics of patients are presented in Table The group of patients with acute HF was significantly older (mean ages 70.9 ± 11.7 years versus...

Ngày tải lên: 14/08/2014, 08:21

... Leveraged Loan Index from the Standard & Poor’s, the Lehman Brothers U.S Corporate Intermediate Bond Index from the Datastream, and the NYSE/AMEX/NASDAQ Value-weighted Index from the Center for ... created another bond price dataset from Datastream for a subset of bonds, containing 91,760 bond-day observations spanning 248 bonds.9 We received the loan defaults data from Portfolio Management Data ... Database”, a comprehensive dataset of domestic corporate bond default dates starting from 1974 Our bankruptcy dataset is from www.bankruptcydata.com Specifically, we identified the firms in the loan price...

Ngày tải lên: 16/02/2014, 02:20

... Default database, prices from numerous broker dealers in distressed debt Bank Loan data from 1996-2002 (for the first two measures), and Standard & Poor’s LossStatsTM database from 1988-2Q-2003 for ... loan market versus retail loan market A final way of stratifying loan trades in the secondary market is to distinguish between the “par” loans (loans selling at 90% or more of face value) versus “distressed” ... recovery rates of loans versus bonds around loan and bond default dates as outlined above Finally, to benchmark our results, we extend our analysis to the return performance of loans versus stocks To...

Ngày tải lên: 15/03/2014, 07:20

... provided data from June 1, 1999, to July 31, 1999, o and from June 1, 2000, to August 31, 2000 In 1999, the spreads are measured after the New Market All Share index had gained 24% from January ... June 1, 1999, to July 31, 1999, from June 1, 2000, to August 31, 2000, respectively, and the median daily share turnover from May 1, 1999, to July 31, 1999, and from June 1, 2000, to August 31, ... average percentage spreads from June 1, 1999, to July 31, 1999, and from June 1, 2000, to August 31, 2000 Turnover, share price, and market value data have been obtained from Datastream Share turnover...

Ngày tải lên: 15/03/2014, 16:20