selenocysteine biosynthesis and the replacement of selenocysteine with cysteine in the pathway
Báo cáo y học: "Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/ cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma"
Ngày tải lên :
26/10/2012, 09:53
... CDDP with regards to clinical response and survival, and also to acute and late toxicity in the treatment of ESCC [16] In this study, the effects of replacing CDDP with NDP on the pharmacokinetics ... treated with CDDP (the CDDP group), and the remaining patients were treated with NDP (the NDP group) This study was conducted with the authorization of the institutional review board and followed the ... difference in the plasma concentrations of 5-FU between the patients with and without severe acute leucopenia, in either groups Similarly, the plasma concentrations of 5-FU in the patients with severe...
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Tài liệu Báo cáo khoa học: Insights into the interaction of human arginase II with substrate and manganese ions by site-directed mutagenesis and kinetic studies Alteration of substrate specificity by replacement of Asn149 with Asp docx
Ngày tải lên :
20/02/2014, 02:21
... consequence of the mutagenic replacements Effects of the His120Asn and His145Asn mutations on the affinity of metal binding to arginase II To further examine the effects of the His120fiAsn and His145fiAsn ... Mn2+A in arginase I and Mn2+B in arginase II Because ligands to the metal ions are strictly conserved in these enzymes, the difference would reside in the length of the ligand– metal separations In ... by agmatine in E coli agmatinase and l-arginine in B caldovelox arginase [37], indicating that the substrate specificity of these enzymes rely mainly in substituents at C-a This has been, in fact,...
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Báo cáo khoa học: Hexadecylphosphocholine inhibits phosphatidylcholine biosynthesis and the proliferation of HepG2 cells pot
Ngày tải lên :
17/03/2014, 11:20
... pmolÆmin)1 per 106 cells in HePC-treated cells) Effect of HePC on enzymes of the CDP–choline pathway According to the observations made above, and bearing in mind that the incorporation of choline ... interfere with the uptake of choline into the cell, leading to a decrease in PC biosynthesis In the present work we exposed the cells to HePC between and h and did not observe any change in the uptake ... contamination of the microsomes and mitochondria in the cytosolic fraction Choline kinase assay Choline kinase (CK) activity was assayed by measuring the rate of [methyl-14C]choline incorporation into...
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The effect of Qigong on general and psychosocial health of elderly with chronic physical illnesses: a randomized clinical trial doc
Ngày tải lên :
28/03/2014, 19:21
... postures and movement, state of mind, and breathing The aim of practicing qigong is to cultivate qi to help the organism stay healthy and vital In China, health and longevity are determined by ... Questionnaire The questionnaire consists of 28 questions on a five-point scale This indicated that the whole spectrum of the five-point scales was utilized in the reflection of quality of life of the participants ... The questions were further categorized into four domains, including physical health domain, psychological domain, social relationship domain and environment domain The Cronbach alpha values Int...
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Báo cáo hóa học: " The molecular dynamic simulation on impact and friction characters of nanofluids with many nanoparticles system" pot
Ngày tải lên :
21/06/2014, 05:20
... analysis and revised the original manuscript XJL participated in discussion of the results and in revising the manuscript All authors read and approved the final manuscript Competing interests The ... However, since the aim of this study is to get the moving state and variation trend of nanoparticles in shock and friction process Considering argon as the base fluid and modeling the interactions ... (XPS), and atomic force microscope The results found that nano-particles take the effect of the antiwearing and friction reducing by the following five aspects such as “tiny polishing"; “tiny ball...
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Creating an Inclusive Environment: A Handbook for the Inclusion of People with Disabilities in National and Community Service Programs ppt
Ngày tải lên :
28/06/2014, 23:20
... t.DisplayCurrentTime(); int theHour = 0; int theMinute = 0; int theSecond = 0; t.GetTime( theHour, theMinute, theSecond); System.Console.WriteLine("Current time: {0}:{1}:{2}", theHour, theMinute, theSecond); ... unboxing Như bạn thấy ngược lại với trình boxing Unboxing sau thực Boxing Đây chương trình minh họa trình boxing unboxing: using System; public class Unboxing { public static void Main() { int ... mảng using System; public class UsingForeach { public static int Main() { int[] intArray = {1,2,3,4,5,6,7,8,9,10}; foreach( int item in intArray) { Console.Write("{0} ", item); } Console.ReadLine();...
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Báo cáo lâm nghiệp: "Evaluation of the growth and health status of selected clone mixtures in comparison with ordinary planting stock" docx
Ngày tải lên :
07/08/2014, 03:22
... alization started in the eighties, at the time of the culmination of air-pollution disaster In that period, within the programme of the gene conservation of indigenous forest tree species in the Krkonoše ... cuttings of the 2nd generation The selection of individuals for further growing was performed on the basis of the complex evaluation of parent trees (the health status was the main criterion, and ... both the individuals with intensive growth dynamics and the slow-growing individuals were selected for a subsequent mixture of clones) After their growing in a nursery they were outplanted in exposed...
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Báo cáo y học: "Rituximab therapy reduces activated B cells in both the peripheral blood and bone marrow of patients with rheumatoid arthritis: depletion of memory B cells correlates with clinical response" potx
Ngày tải lên :
09/08/2014, 14:22
... participated in the design and conduction of the study and drafted the manuscript PS participated in the design of the study, performed the statistical analysis of the data and drafted the manuscript ... analysis of flow cytometry experiments HAP participated in the design of the study and drafted the manuscript HK participated in the design and conduction of the study, was involved in patient care and ... both in the PB and in the BM of RA patients (d) Representative flow cytometry histograms of HLA-DR expression in PB and BM CD19+-gated cells of a RA patient at baseline and after treatment with...
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Báo cáo y học: "The accuracy of echocardiography versus surgical and pathological classification of patients with ruptured mitral chordae tendineae: a large study in a Chinese cardiovascular center" ppt
Ngày tải lên :
10/08/2014, 09:22
... enhancement, and vegetation, as well as being combined with AV damage The incidence of extended subvalvular chordae in the myxomatous group was higher than that in the other groups, and the incidence of ... shortening, and chordal transfer The methods of MV replacement included a mechanical prosthetic valve and bioprosthetic valve The method of choosing the type of surgical method depended on the location ... thickening combined with AV damage in the CRV group was higher than that in the other groups Infective endocarditis patients were younger than those in the other groups, and there was a higher incidence...
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Báo cáo y học: " Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis" pdf
Ngày tải lên :
12/08/2014, 18:20
... mRNA and protein levels This finding would open a new insight in the field of monocyte-lineage cell biology and of the diseases where this lineage cells play a prominent role In the latter part of ... collection and acquisition of the data and draft of the manuscript TA and TK was involved in the interpretation and design of the study, and also drafted the manuscript All authors have read and approved ... prostaglandin D2 synthase, the transcription factor GATA-1, and the interleukin (IL)-13 inhibitory receptor IL13Rα2 [5, 8] In support of these in vitro data, the mature RasGRP4+ MCs that reside in the...
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Báo cáo y học: "Serologic and PCR testing of persons with chronic fatigue syndrome in the United States shows no association with xenotropic or polytropic murine leukemia virus-related viruses" pot
Ngày tải lên :
13/08/2014, 01:20
... the right of the WB Sizes of expected viral proteins are provided to the left of the WB b Detection of XMRV antibodies in three experimentally-infected macaques (RII, RYh and RLq) Days post infection ... Disease Control and Prevention The findings and conclusions in this report are those of the authors and not necessarily represent the views of the Centers for Disease Control and Prevention Author ... blood or in other reservoirs Given the recent finding that an XMRV antibody test, using even a single XMRV protein, had 100% sensitivity for XMRV detection in monkeys after the second week of infection...
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Báo cáo y học: "Influence of enrollment sequence effect on observed outcomes in the ADDRESS and PROWESS studies of drotrecogin alfa (activated) in patients with severe sepsis" pptx
Ngày tải lên :
13/08/2014, 11:22
... and stockholders of Eli Lilly and Company Authors' contributions P-FL and EA participated in the conception and design of the study, in the development and conduct of analyses, and in the clinical ... population The use of severity scoring systems in clinical trials may require training and validation of the training to ensure proper collection of severity of illness information Helps to ensure the ... trials and data collection WLM, JJ, and DRN participated in the conception and design of the study, in the development and conduct of analyses, and in drafting the manuscript MDW participated in...
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Tài liệu Growth and nutritional status of children with homozygous sickle cell disease ppt
Ngày tải lên :
12/02/2014, 19:20
... occurs early in life Booker et al.25 reported weight deceleration starting at about 4–6 months of age, coinciding with the onset of crises and infections and continuing during the 1st years of life ... American study of 170 children (aged 2–12 years) with SCD, 22% were ,5th centile in height and/ or weight,96 and the serum levels of zinc, retinol, pre-albumin and retinol binding protein were significantly ... weight and MUAC.111 Reduced levels of other B vitamins including B12112 and riboflavin113 have been reported Folic acid and vitamins B6 and B12 are important co-factors in metabolism of the sulphurcontaining...
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Tài liệu SEXUAL AND REPRODUCTIVE HEALTH OF PERSONS WITH DISABILITIES doc
Ngày tải lên :
13/02/2014, 15:20
... of the same quality R to persons with disabilities as to others, including on the basis of free and informed consent by, inter alia, raising awareness of the human rights, dignity, autonomy and ... of the same quality R to persons with disabilities as to others, including on the basis of free and informed consent by, inter alia, raising awareness of the human rights, dignity, autonomy and ... “provide persons with disabilities with the same range, quality and standard of free or affordable health care and programmes as provided to other persons, including in the area of sexual and reproductive...
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Tài liệu Báo cáo khoa học: Dmrt1 genes at the crossroads: a widespread and central class of sexual development factors in fish pdf
Ngày tải lên :
14/02/2014, 19:20
... at higher levels in testes than ovaries The deep interest in Dmrt1 in the field of sex determination in fish came with the discovery of a dmrt1 homologue on the Y chromosome of the fish medaka (Oryzias ... zinc ion each, and binds to the minor groove of the DNA [6] Dmrts were originally described to play important roles during sex determination in flies and worms by regulating several aspects of ... studied in the context of gonadal induction and maintenance, illuminating its important function But what about the other dmrt genes? Table summarizes the expression pattern of these genes in fish...
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Tài liệu Báo cáo khoa học: Tryptophan tryptophylquinone cofactor biogenesis in the aromatic amine dehydrogenase of Alcaligenes faecalis Cofactor assembly and catalytic properties of recombinant enzyme expressed in Paracoccus denitrificans pptx
Ngày tải lên :
19/02/2014, 07:20
... limiting with ‘fast’ substrates The lack of inhibition observed with benzylamine (Fig 5A) in comparison to the inhibition observed with tryptamine (Fig 5B) suggests differences in binding of the ... represents the ionization of Asp128b This being the case, the effect of substrate binding would be to lower the pKa of this group to 6.0 (i.e the value measured in the plot of klim vs pH; Fig 4C) The ... is < 6% of the determined value Kinetic and thermodynamic parameters were obtained from fitting data to the Eyring equation sion of AADH, A faecalis and P denitrificans were cultured in minimal...
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Báo cáo " Study on the characteristics and catalytic properties of Pt/SBA-15 in the selective oxidation of D-Glucose " potx
Ngày tải lên :
05/03/2014, 11:21
... dispersed with the size under 6nm in the channels of SBA-15 and at this state, Pt/SBA-15 catalyst showed the highest activity and selectivity in the oxidation of glucose When increasing the content of ... continuously to maintain pH value at during the oxidation process In table 2, we also see that increasing the Pt contents led to decrease in catalytic activity The average particle size of the ... (48h) and 97.43Ǻ (72h) In these XRD patterns, we also see that two weak peaks indexed as (110) and (200) diffractions of 24h sample are not clear and the intensity of these peaks increases in accordance...
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Báo cáo khoa học: Comprehensive interaction of dicalcin with annexins in frog olfactory and respiratory cilia pdf
Ngày tải lên :
07/03/2014, 05:20
... as thin dotted lines in (C) and (D) The result obtained in the presence of dicalcin and all of the annexins (E) was compared with the calculated sum of each of the initial rates obtained in (B)–(D) ... for the interaction of frog annexin A1 and annexin A2 with dicalcin Consistently, we observed that the 35 kDa forms of annexin A1 and annexin A2 found in the fraction of the binding proteins of ... annexin A1, annexin A2, annexin A4 and annexin A5 to identify which annexins were in the fraction of the 38 kDa and the 35 kDa proteins Cloning of annexin cDNAs On the basis of the partial amino...
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Báo cáo Y học: Agmatine oxidation by copper amine oxidase Biosynthesis and biochemical characterization of N-amidino-2-hydroxypyrrolidine pdf
Ngày tải lên :
17/03/2014, 23:20
... met-hemoglobin in the presence of N-amidino-2-hydroxypyrrolidine as the substrate instead of L-arginine (data not shown) Figure shows the molecular models of the human NOS-II: and bovine trypsin:N-amidino-2-hydroxypyrro- ... concentration within the standard deviation (± 5%) Model building of the NOS-II: and trypsin: N-amidino-2-hydroxypyrrolidine complexes Molecular models of the human NOS-II: and bovine trypsin:N-amidino-2-hydroxypyrrolidine ... short, being completed within the mixing time (% 15 s) Values of the first-order rate-limiting catalytic constant (kcat) and of the Michaelis constant, as determined in the absence of the inhibitor...
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Sexuality Issues and Gynecologic Care of Adolescents with Developmental Disabilities potx
Ngày tải lên :
28/03/2014, 14:20
... characteristics) Gaining of 25% of final height (distal growth [eg, of feet] may precede that of proximal parts [eg, the tibia] by 3–4 months) Doubling of lean and nonlean body mass (gaining by 50% of the ideal ... siblings, and other relatives One survey noted that of every 1000 college females reported being victims of incest by their father.88 In the classic Weinberg89 study of 103 incest victims, 78% involved ... changing scene of step-parents, live -in- lovers of divorced parents, and changing sex partners, fueling the incidence of sexual assault on the children and adolescents in the home.90 Those with...
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