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Isolation and characterization of aurora a kinase interacting protein (AKIP), a novel negative regulator for aurora a kinase
... dynein, kinesins and kinesin-related proteins and their dynamic temporal and spatial coordination play an essential role during the process During the telophase, nuclear division occurs Actin ... initially to the duplicated centrosomes at the end of S phase, translocating to mitotic spindle from prophase through telophase Activation of centrosomal Aurora-A at late G2 phase is essential ... Thus, Aurora-A overexpression might accelerate or potentiate the multistep tumorigenesis Interestingly, kinase activity of Aurora-A is not essential for the induction of aneuploidy and centrosome...
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Báo cáo khoa học: The mystery of nonclassical protein secretion A current view on cargo proteins and potential export routes pdf
... receptor that preferentially binds galectin-1 [79] This latter example is of particular interest as it provides a potential molecular mechanism for how tumor cells can differentially interact with ... export is the Na+/K+-ATPase [68] This conclusion was based initially on the observation that cardiac glycosides such as ouabain partially inhibit FGF-2 export [50,68,69] This was further strengthened ... process of galectin-1 has been shown to be regulated based on cell differentiation For example, during the differentiation of muscle cells a massive increase of galectin-1 export has been observed...
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AORTIC VALVE STENOSIS – CURRENT VIEW ON DIAGNOSTICS AND TREATMENT pot
... when the pressure drop across a stenotic orifice is partially recovered distal to the obstruction from conversion of kinetic energy into potential energy Continuous-wave Doppler measures the point ... years at initial evaluation), observed that the obstruction tends to increase over time, especially in cases with higher gradients on enrolment Whereas only 20% of those patients with initial peak- ... injury with potential neurologic complications and the need of surgical exposure Above all, the retrograde femoral arterial approach remains the most commonly used The potential associated complications...
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Guarantee Operations at Agribank – Current Situation and Recommendations.doc
... scale and higher value of the international commercial transactions are To avoid and reduce potential loss, the banks have used various measures such as more legal procedures on dispute settlement ... upheaval L/C is a typical guarantee against documents in which the beneficiary must present essential documents required in the L/C for payment.1 It is more advantageous for the principal to use ... business or production situation, customers’ prestige, they are unable to evaluate the customers’ potential and realize possible risks as well This, therefore, causes in immeasurably severe consequences...
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Establishment of Effluent Standards for Industrial Wastewaters in Korea: Current Issues and Suggestions for Future Plan
... analyses (Choi et al., 2004) The nu mber of pollutants regulated under effluent standards was initially 7, and now it increase d to 32 (Table 1) It seems that the range of control was greatly increased,...
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RFID current applications and potential economic benefits (IBM)
... reliable architecture Sensor and Actuator Solutions emerging business unit in place - leading RFID initiatives for IBM Consulting partner for leading industry players Wireless Broadband & Sensing Solutions ... Applications and Public Policy Considerations Security & supply chain optimization: Joint IBM/Maersk initiative to develop a solution to provide real time visibility on containers and goods transported ... ibm.com/industries/wireless/ OECD Forum on RFID Applications and Public Policy Considerations Successful RFID initiatives require focus in three key areas: Business Strategy Business Process & Applications Technical...
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Tài liệu Ecosystems and Human Well-being: Current State and Trends, Volume 1 pdf
... sea For example, pollination is an essential link in the production of food and fiber Plant-eating insects and pathogens control the populations of many potentially harmful organisms The services ... land use) The sink may be explained partially by afforestation, reforestation, and forest management in North America, Europe, China, and other regions and partially by the fertilizing effects of ... intrinsic inertia—the tendency to continue changing even when the forces causing the change are relieved The complexity of coupled human–ecological systems, together with our state of partial knowledge,...
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Tài liệu BÁO CÁO " CURRENT STATUS AND ORIENTATION OF RESIDENTIAL AREAS IN QUANG XUONG DISTRICT, THANH HOA PROVINCE, VIETNAM " pot
... of residential areas, the size of residential areas, population size of residential areas, the quality of transportation systems in residential areas, the quality of housing in residential areas, ... residential areas (6 urban residential areas and 386 rural residential areas) On average, each commune has 10 residential areas and there are 676 people and 166 households in each residential area ... Total residential areas Households Average indicators - The size of residential area - The residential areas land per household m - Land for housing per household m - The residential areas area...
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Draft Report on Alternative (Non-Animal) Methods for Cosmetics Testing: current status and future prospects – 2010 doc
... potential of embryonic stem cells to differentiate into all cell types of the mammalian 510 organism (pluripotency) provides the scientific rationale to assess adverse effects on the 511 differentiating ... are seeded in a high density and 500 undergo differentiation into chondrocytes and neurons without additional stimulation The 501 differentiation after exposure to test chemicals is analysed ... inclusion of a 467 mammalian metabolic activation system was essential for the correct prediction of the 468 teratogenic potential of substances However, FETAX still requires further development...
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Current Issues and Future Direction in Kidney Transplantation Edited by Thomas Rath potx
... early postoperative period, the potential adverse effects of immunosuppression, and the importance of compliance with immunosuppressive therapy The potential advan‐ tages and disadvantages of ... of pre-operative evaluation is to determine whether potential transplant candidates have any active cardiac condition both during the initial evaluation and immedi‐ ately before an anticipated ... hemodynamic stability are the main factors for evaluating a potential donor In contradistinction, the imaging methods constitute the initial assessment of the living donor in the kidney transplantation,...
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Internal audit independence and objectivity: a review of current literature and opportunities for future research ppt
... internal auditors to “have an impartial, unbiased attitude and avoid conflicts of interest.” The related Practice Advisory statement stresses the need to avoid potential and actual conflicts of interest ... audit to be a training ground for future potential managers The internal audit manager described the function as a fishing pond full of high potential, suggesting that, as a result, the function ... understand the expanding scope of internal audit practice” (Cooper, Leung and Wong, 2006) An initial phase of this study has resulted in three related literature reviews Cooper et al (2006) examined...
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Báo cáo khoa học: "Machine Translation: its History, Current Status, and Future Prospects Jonathan Slocum Siemens" pdf
... translation sophistication Of s p e c i a l r e l e v a n c e to MT i s t h e f a c t t h a t essentially all translations for dissemination ( e x p o r t ) a r e r e v i s e d by more h i g h l ... category as degree '~ocal scope" characterizes a system (e.g., SYSTRAN) in which words are the essential unit driving analysis, and in which that analysis is, in effect, performed by separate procedures ... s e n t e n c e (a " g l o b a l " a p p r o a c h ) r a t h e r t h a n r e l y on intra-sentential h e u r i s t i c s t o c o n t r o l l i m i t e d word transposition (the "local" approach);...
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Epidural Analgesia – Current Views and Approaches Edited by Sotonye Fyneface-Ogan docx
... Required volume of epidural infusion j Notes: a Initial concentration, i.e solution in the prefilled bag b Initial full dose, added to the initial solution in the prefilled bag c Pain score measured ... dose-dependent analgesia, an antianalgesic response with increased pain compared with placebo was observed in men receiving nalbuphine Partial agonists produce only a partial response in binding to ... health care team about the dangers and potential attributes of administration of sedating medications concomitant with analgesia and the importance of initiating rational multimodal analgesic plans...
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MULTIPLE SCLEROSIS CURRENT STATUS AND STRATEGIES FOR THE FUTURE ppt
... Key advantages of current animals models include the fact that the initiating trigger is known, the exact time of the initiating event is known, a great deal is known about the genetics and the ... resulting in a substantial but unproductive investment in time and money These erroneous claims have also led to the treatment of patients with inappropriate, expensive, and potentially harmful therapies ... endogenous pluripotent neural stem cells and their potential to be used to repair damaged neural cells in the brain • Discovery of the therapeutic potential for neural, glial, and stem cell transplantation...
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Brazil''''s Capital Market: Current Status and Issues for Further Development pot
... for sizable capital flows in the medium term During the last decade, Brazil has achieved substantial progress in capital market development The menu of available financial instruments has been ... Side: Enhance Supply and Attractiveness of Long-Term Instruments 14 B Investors’ Side: Boost Potential in Mutual Funds 15 C Changes in the Role of BNDES 17 IV Conclusions ... stability From investors’ point of view, deep and liquid capital markets increase the supply of differentiated assets facilitating investment choices Perhaps most importantly for emerging markets (EMs),...
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Computational Intelligence in Electromyography Analysis – A Perspective on Current Applications and Future Challenges docx
... membrane potential could be modelled by an exponential curve When this curve crosses a certain threshold, a new action potential is fired This leads to the repetitive firing of action potentials with ... generating a potential a1·IR(t) The second dipole originates at time ∆t, propagates towards the tendons, generating a potential a2·IR(t-∆t) [Fig 3(c)] Hence the total potential recorded by the ... and initiation of depolarization Electrophysiologically, the motor end-plate is the region where the motor end-plate potential is generated, hence where the intracellular action potential of...
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CURRENT FRONTIERS AND PERSPECTIVES IN CELL BIOLOGY doc
... made systematic studies of the potentially new organelle difficult Later on, studies of AL profited from the development of antibodies against nucleoporins Initial data indicating that ALPCs and ... between AL and the Golgi complex Initial double immunofluorescence labeling of AL and the Golgi complex of bovine epithelium cells, however, could not confirm any spatial relationship between both ... Cytoplasm 131 Naoko Fujiwara, Takuya Shiki and Seiji Masuda 105 VI Contents Chapter Membrane Initiated Effects of 1α,25-Dihydroxyvitamin D3 in Prostate Cancer Cells: Effects on AP1 and CREB Mediated...
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The health of Canada’s elderly population: current status and future implications pot
... and utilization at older ages, because the health needs of elderly women are likely to be substantially different from those of elderly men Being an elderly woman is associated with other attributes ... housework and shopping The pattern of need was similar among elderly men, but the rates were substantially lower, even among those aged 75 and over These sex-related differences are linked to the ... find alternative ways of providing nonmedical help Ultimately, it leads elderly people into residential care or even acute care facilities There is also the question of whether elderly people who...
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ARGENTINA FROM A BRITISH POINT OF VIEW AND NOTES ON ARGENTINE LIFE docx
... Company was evicted from the lands, and entered into negotiations with the Government of the Province of Santa Fé for indemnification These negotiations went on for some years without coming to any ... paid to the vendors, leaving a balance of £199,434 to meet the preliminary expenses and the initial cost of opening up the new properties After some years it was found necessary to write off ... of approximately 88 Spanish leagues, or 530,000 English acres, which became the subject of negotiations and lawsuits between this Company, the Provincial Government of Santa Fé, and other parties,...
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