role of oxidative stress in development of complications in diabetes
Báo cáo khoa học: Effect of oxidative stress and involvement of poly(ADP-ribose) polymerase (PARP) in Dictyostelium discoideum development doc
... abnor- mal fruiting bodies with larger fruits. PARP involvement during oxidative stress- induced developmental changes in D. discoideum To determine the role of PARP in oxidative stress- induced developmental ... PARP inhibitor, on oxidative stress- induced changes in D. discoideum development. Interestingly, oxidative stress resulted in PARP activation within 5 min that was inhibited by benzamide. Oxidative ... an important role under oxidative stress [21]; however, there is no report on the role of PARP in D. discoideum development. We have investigated the role of PARP in D. discoideum development by inhibiting...
Ngày tải lên: 23/03/2014, 07:20
Tài liệu Báo cáo khoa học: Enhancement of oxidative stress-induced apoptosis by Hsp105a in mouse embryonal F9 cells pptx
... important role in protection of neuronal cells against stress- induced apoptosis [26]. In accordance with these findings, ischemia/reperfusion in the rat forebrain induces the expression of HSP105/110 ... activation of p38 induced by oxidative stress, we further examined whether its activation is responsible for the induction of apoptosis in F9 cells using SB202190, a potent inhibitor of p38. As shown in ... mitogen-activated protein kinase (p38). Furthermore, oxidative stress- induced apoptosis was suppressed by SB202190, a potent inhibitor of p38, in F9 cells. These findings indicated that the activation of p38...
Ngày tải lên: 21/02/2014, 03:20
Ambient particulate air pollution induces oxidative stress and alterations of mitochondria and gene expression in brown and white adipose tissues ppt
... 8:20 http://www.particleandfibretoxicology.com/content/8/1/20 Page 8 of 14 inflammatory response and IR development, were exam- ined in mice. As shown in Figure 3, PM 2.5 exposure induced a marked increase in macroph age (F4/80 + cells) infiltration in eWAT. ... effect of ambient PM 2.5 onWATandBATspecificgenesin different adipose depots. There are several major find- ings in this study. First, exposure to PM 2.5 resulted in oxidative stress in BAT. ... expression in iBAT (Relative to FA) FA PM 2.5 A B Figure 4 Immunohistochemical examination of uncoupling protein 1 (UCP1) in the iBAT. A. iBAT was stained by antibody against UCP1 and counterstained...
Ngày tải lên: 06/03/2014, 19:20
Báo cáo khoa học: The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells doc
... provide new information about the function of ANT proteins in the regulation of cell death⁄ survival processes. We analyzed the role of ANT1 and ANT2 isoforms in a human glioblas- toma cell line, the ... that silencing of ANT1, but not ANT2, strongly reduced ADF viability by inducing an increase in oxidative stress that leads to cell death. We also demonstrated that the ANT1-silencing effect ... FEBS ANT1-silencing effect on cell viability might be a result of the onset of a programmed cell death process, we analyzed the effect of siRNA in the presence of the protein synthesis inhibitor puromycin....
Ngày tải lên: 29/03/2014, 09:20
báo cáo hóa học: " The microglial NADPH oxidase complex as a source of oxidative stress in Alzheimer''''s disease" ppt
... use of vitamin E and vitamin C in combi- nation reduced the prevalence and incidence of AD in an elderly population; however, the use of either of these vitamins alone had no effect [110]. Finally, ... complex leads to the initiation of complex signaling events leading to protein tyrosine phosphorylation and activation of the src-family kinases Lyn and Fyn as well as the tyrosine kinase Syk [30,32,52]. ... inhibition of phosphati- dylinositol-3 kinase (PI3K) attenuates ROS production. These findings suggest that these kinases are involved in upstream signaling cascades responsible for activating NADPH...
Ngày tải lên: 19/06/2014, 22:20
báo cáo hóa học: " Biomarkers of oxidative stress and its association with the urinary reducing capacity in bus maintenance workers" pptx
... response of the organism to particle-induced oxida- tive stress. The observed increase of reducing species in urine would mirror an increased level in blood originat- ing from a response to oxidative ... only 10% of urate is excreted in the urine (the remaining 90% being recirculated by the renal system [3]), an increase of this antioxidant in blood will also lead to an increase in urine. The ... been reported to increase the serum levels of uric acid in North Carolina police officers [4]. A similar increase of plasma antioxidants in response to an increased oxid a- tive stress was observed in newborns...
Ngày tải lên: 20/06/2014, 00:20
ROLE OF THE ADIPOCYTE IN DEVELOPMENT OF TYPE 2 DIABETES potx
... Cytokine- mediated modulation of leptin and adiponectin secretion during in vitro adipogenesis: evidence that tumor necrosis factor-α- and interleukin-1β treated Role of the Adipocyte in Development ... impair insulin signaling through activation of protein kinase C θ (PKCθ). PKCθ phosphorylates insulin receptor substrate I, thus preventing the phosphorylation involved in the insulin signal ... the Adipocyte in Development of Type 2 Diabetes 16 effects (Tang et al., 2001), acting as co-adjuvants in the reduction of the incident of diabetes (Doggrell, 2002), increasing vascular function...
Ngày tải lên: 27/06/2014, 19:20
Báo cáo khoa học: " Induction of oxidative stress and lipid peroxidation in rats chronically exposed to cypermethrin through dermal application" pps
... significantly reduced (p ＜ 0.05) in all groups compared to the control group. Similar finding have been reported in other study during oxidative stress [24]. No significant changes in GST activity was ... resistant strain of insect [38]. GST levels were also increased significantly after 30 days of exposure to protect RBCs from oxidative damage. Further significant decreases in GSH levels in our study ... oxidative damage [16]. Increased activity of GST was reported in Drosophila melanogaster after insecticide exposure [27]. Elevated GSTs were reported in Nilaparvata lugens, a pyrethroid insecticide...
Ngày tải lên: 07/08/2014, 23:22
The effects of oxidative stress on female reproduction: a review ppt
... regulator of proper development and remodeling. Angiogenic factors are known to play key roles in the maintenance of proper spiral artery remodeling. Thus, the involvement of uterine NK cells in RPL ... Durak I: Role of oxidative stress in intrauterine growth restriction. Gynecol Obstet Invest 2007, 64:187–192. 228. Karowicz-Bilinska A: Lipid peroxides concentration in women with intrauterine growth ... JG: Role of oxidative stress in endometriosis. Reprod Biomed Online 2006, 13:126–134. 22. Agarwal A, Gupta S, Sharma RK: Role of oxidative stress in female reproduction. Reprod Biol Endocrinol...
Ngày tải lên: 05/03/2014, 16:20
a comparative analysis of the cognitive moral development of independent public auditors in selected public accounting firms and bank examiners in selected federal banking regulatory agencies
... Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction ... without permission. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction ... without permission. Reproduced with permission of the copyright owner. Further reproduction prohibited without permission. Reproduced with permission of the copyright owner. Further reproduction...
Ngày tải lên: 03/06/2014, 02:11
Báo cáo y học: " Effectiveness of antiretroviral therapy and development of drug resistance in HIV-1 infected patients in Mombasa, Kenya" doc
Ngày tải lên: 10/08/2014, 05:21
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