role of capital market authority in the economy
The Role of Digital Identity Management in the Internet Economy doc
... managing and protecting digital identities, with a view to strengthening confidence in the online activities crucial to the growth of the Internet Economy. The primer is a product of the Working ... protection of individuals and their digital identities. As a key factor in increasing trust in online activities, IdM is also a key factor in fostering the growth of the Internet economy. Given the ... maintained in multiple accounts within the organisation. The organisation is in some sense wasting resources and duplicating efforts in maintaining separate profiles with (mostly) the same information....
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Tài liệu Role of diffusion-weighted imaging in the diagnosis of gynecological diseases pdf
... awell-defined hyperintensity mass in the cervical area. The shape of the uterine cervix is distorted in the DWI (arrowhead). d On the ADC map the tumor is hypointense (arrow) and the normal ... imaging technique (SENSE factor of 2). Imaging time of DWI was 90 s for 20 slices.Detection of uterine malignancy The ADC values of uterine cancers are lower than of normal tissue. On the other ... with uterine leiomyomas and ableeding cyst. a Axial T2-WI shows an area of hypointensity in the center of the cystic component (arrow). b On T1-WI with fatsuppression the area in the cystic...
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Tài liệu Báo cáo khoa học: Mitochondrial targeting of intact CYP2B1 and CYP2E1 and N-terminal truncated CYP1A1 proteins in Saccharomyces cerevisiae ) role of protein kinase A in the mitochondrial targeting of CYP2E1 pdf
... of PKA in the mitochondrial targeting of CYP2E1 The role of PKA in mitochondrial targeting of CYP2E1 was investigated using two approaches. The first approach involved measuring the level of mito-chondrial ... microsomes requires the co-translational insertion of the newly synthesized proteininto the microsomal membrane, where the N-terminalhydrophobic signal sequence of the protein interactswith a ... mitochondria-targeting signal in the yeast system.Mitochondrial localization of intact CYP2E1 in yeast cellsBecause of the existing ambiguity in the literature on the nature and extent of CYP2E1 import into...
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Tài liệu Báo cáo khoa học: Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enol pyruvyl transferase docx
... providedfurther insight into the molecular mechanism driving the formation of the covalent C115–fosfomycin adduct. Aconservative exchange of K22 to arginine maintains fosfo-mycin binding, while ... form of the protein. The results obtained with the K22V/R120K doublemutant protein point toward a central role of arginine 120 in the conformational process occurring during catalysis.Therefore, ... arationale for these findings: the side chain amino group of K22 engages in a salt-bridge interaction with the phospho-nate group of fosfomycin (Fig. 5). Clearly, the guanidiniumgroup of arginine can,...
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Tài liệu Báo cáo khoa học: Electrostatic role of aromatic ring stacking in the pH-sensitive modulation of a chymotrypsin-type serine protease, Achromobacter protease I pdf
... dependence of the pH-activity curve of API The pH-activity profiles depending on NaCl concentrationwere determined as part of the investigation into the shielding from solvent of the electrostatic interactionbetween ... position. In the struc-tural deviation, the solvent ASA of the side-chain of His210increased with the decrease in size of the side-chain atresidue 169 (Table 1 and Fig. 3A). However, the ASAs of Asp113 ... size of the side-chain at residue 169 and the pK2showed a clear linear relationship (Fig. 3B). The pK2increased as the size of the residue at position 169 increased. The effect of the size of...
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Báo cáo khoa học: Role of DptE and DptF in the lipidation reaction of daptomycin ppt
... by the C domain of the initiation module of dapto-mycin. That DptE and DptF are involved in the lipidation process of daptomycin was first shown byMiao et al. [1]. In their work, the daptomycin ... is GLDSV,indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) orleucine (L) in the conserved sequence. To determinewhether DptF is the putative ... [37].Interestingly, in the case of the lipopeptide surfactin,neither an acyl CoASH ligase-like domain nor an ACPcould be identified within the biosynthetic gene clusterusing bioinformatic tools...
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Báo cáo khoa học: "Examining the Role of Linguistic Knowledge Sources in the Automatic Identification and Classification of Reviews" doc
... documents and find that the fea-ture vectors corresponding to some of these docu-ments (particularly the short ones) have all zeroes in them. In other words, none of the bigrams from the training set ... cap-turing two different situations, one in which the author himself likes the movie, and in the other, the author’s cousin likes the movie. The over-generalization resulting from these “stemmed” ... available.612 Proceedings of the COLING/ACL 2006 Main Conference Poster Sessions, pages 611–618,Sydney, July 2006.c2006 Association for Computational LinguisticsExamining the Role of Linguistic Knowledge...
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Báo cáo khoa học: Role of calcium phosphate nanoclusters in the control of calcification pot
... used to describe the bindingisotherms obtained previously for the b-casein 1–25 phos-phopeptide in this pH range, and the same model wasadapted to fit the binding isotherm of OPN 1–149 mea-sured ... mixture of scattering from copolymer micelle-like nanoclus-ters and free peptide. The scattering of the nanoclusters was obtained by subtracting the scattering of the free peptide from the total ... solutionscontaining high concentrations of Ca, Piand the phospho-peptide, the concentration gradients generated and theirpersistence during inefficient mixing can allow the initalACP to mature into...
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Báo cáo khoa học: Membrane compartments and purinergic signalling: the role of plasma membrane microdomains in the modulation of P2XR-mediated signalling pot
... dur-ing lipid raft isolation. Moreover, these studies haveprovided some insights into the significance of the localization of the P2X7receptors in lipid rafts regard-ing the regulation of intracellular ... (glycero-)sphingolipids. In addition the fatty acid chains of the phospholipids composingthese rigid domains are generally more saturated thanthose in the lipids of the surrounding membrane. In fact, this ... muscarinic receptors, endo-thelin receptors, rhodopsin) are located in lipid rafts[65–70] where they are in close proximity to theirtransducing GTP-binding protein (Gs, Gi, Go, Gq andtransducin...
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Báo cáo khóa học: The role of N-linked glycosylation in the protection of human and bovine lactoferrin against tryptic proteolysis pdf
... Properties of the iron-binding site of the N-terminal lobe of human and bovine lactotransferrins. Importance of the glycanmoiety and of the non–covalent interactions between the N- andC-terminal ... Archimedesweg, Leiden, the NetherlandsLactoferrin (LF) is an iron-binding glycoprotein of the innate host defence system. To elucidate the role of N-linkedglycosylation in protection of LF against proteolysis, ... such as the pancreaticenzyme trypsin has been suggested [19,20]. The experiments described herein further elucidate the role of N-linked glycosylation in the protection of lactofer-rin against...
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