role of capital market authority in investors protection

Ngày tải lên: 30/03/2014, 13:20

... Ten proteins were detected as IgE-binding proteins and 8 proteins as IgG4-binding proteins, with high IgE de- tection rate and specificity. Among the IgE-binding proteins, the proteins with ... changes in fat intake since the amount of dietary fat (30% of total energy) was main- tained constant during the intervention. Similarly, in a 4-week randomized dietary intervention trial of male ... food intake and gastric emptying [69]. These effects were attributed in part to an increase in circulating levels of cholecystokinin. Similarly, in rats fed a hy- percholesterolemic diet, ingestion...

Ngày tải lên: 31/10/2012, 14:59

Ngày tải lên: 25/10/2013, 05:20

... echo-planar MR imaging and ADC mapping in the differential diag- nosis of ovarian cystic masses: useful- ness of detecting keratinoid substances in mature cystic teratomas. J Magn Reson Imaging 22:271–278 24. ... the future of MRI in patients with gynecological diseases. Examination of the female pelvic region using DWI DWI is obtained by measuring signal loss after a series of two motion-providing gradient ... useful in detecting pelvic lymph node metastasis in patients with cervical and uterine cancers. However, the method com- bining size and relative ADC values was proposed by using a combination of...

Ngày tải lên: 13/02/2014, 06:20

... targeting of CYP2E1 The role of PKA in mitochondrial targeting of CYP2E1 was investigated using two approaches. The first approach involved measuring the level of mito- chondrial targeting of wild-type ... importance of PKA in protein trafficking [47,48]. In this study, we used PKA knockout mutants to determine the role of PKA in mitochondrial targeting of CYP2E1. In mutants lacking PKA, CYP2E1 was ... were resuspended in SEM buffer containing indicated concentrations of digitonin (0.05% to 0.4%, w ⁄ v) for 30 min on ice with occasional mixing. Digitonin-soluble and digitonin-insoluble fractions were...

Ngày tải lên: 18/02/2014, 16:20

... double-chain insulin is synthesized in vivo as a single-chain precursor (preproinsulin) and folded as proinsulin, in which a connecting peptide of 35 residues links the C terminus of the B chain and ... Sciences, Chinese Academy of Sciences, Shanghai, China We have investigated the in vitro refolding process of human proinsulin (HPI) and an artificial mini-C derivative of HPI (porcine insulin precursor, ... character- ization of the unfolding of insulin and proinsulin using the reductive unfolding method has not been thoroughly investigated. We have characterized the unfolding process of an artificial porcine insulin...

Ngày tải lên: 19/02/2014, 12:20

... fosfomycin binding due to charge–charge repulsions. Most interestingly, the uncharged valine side chain completely abolishes fosfomycin binding in the absence of UDPNAG. Clearly, UDPNAG binding creates additional ... not interact with R124 in the ternary complex [20]. Hence, the mechanism of binding of fosfomycin by reinforcement of an initial binding site (mainly K22 and R397) through recruit- ment of secondary ... Lysine 22 and arginine 120 in MurA (Eur. J. Biochem. 271) 2685 the positively charged side chain of K22 participates in fosfomycin binding, thus providing a rationale for the loss of fosfomycin...

Ngày tải lên: 19/02/2014, 13:20

... that the N-terminal domain is involved in protein–protein interactions with other hydrophilic domains of neighboring integral membrane subunits, and interspecies interactions are incompatible. From ... the bovine complex a large subdomain is made up of  20 integral membrane proteins contributing > 60 transmem- brane segments. Some of these must be intimately involved in proton pumping. Another ... one might expect a protein to be inserted into the inner membrane, but it is missing a major portion of the domain localized in the intermembrane space. A comparison of all the known mammalian...

Ngày tải lên: 19/02/2014, 16:20

... family of thiolate-ligated constitutive or inducible hemoprotein isoforms [281], exhibiting insign ificant sequence identity with P450s in the heme-binding region [282], but bearing a C-terminal flavoprotein ... B. (1994) The pteridine b inding site of brain nitric oxide synthase. Tetrahydrobiopterin binding k inetics, specificity, and allosteric interaction w ith the substrate d omain. J. Biol. Chem. 269, ... cis-dihydroxylation of a romatic rings, in itiating aerobic degradation of aromatic compounds in soil bacteria, and are targets for bioengineering in bioremediation [204]. They a re a consortium of two o...

Ngày tải lên: 19/02/2014, 16:20

... periods of times (0–60 min) at 37 °C. The concentration of the biotinylated Ig remaining on the cell surface was then quantified by measuring the binding of [ 125 I]Streptavidin. In the absence of ... They were then incubated with 0.25 mL of incubation medium containing 2 lgÆmL )1 of biotinylated R5T-34 monoclonal Ig [30] at 4 °C for 30 min. In some cases, monensin 40 l M was added to the incubation ... domain and devoid of any tag was not functional [27], while a mutant containing four amino acids of the ectodomain and including a rhodopsine tag was found constitutively activated [29]. In agreement...

Ngày tải lên: 21/02/2014, 00:20

... University Regional Learning Alliance – workforce development and training/collaborations with business and industry; meeting the training and education needs of businesses within 60 mile radius in Northern ... $28,000 in average annual salary) Preserving Value Continuing education is important to preserving the market value of specialized education – particularly in professional fields Continuing education ... University Small Business Initiative in the Frehn Center for Management; offering information and assistance to individuals and groups planning to start a new business Indirect Contributions...

Ngày tải lên: 21/02/2014, 01:20

... this protease at pH9 [10]. Further interest in the aromatic stacking is in the role of the electrostatic properties in enzymatic catalysis of API, and in distinguishing the functionally catalytic ... p interaction in the packing of the adenine ring in protein structures. Advan. Protein Chem. 39, 125–189. 20. Brandl, M., Weiss, M.S., Jabs, A.S., ¸ hnel,J.&Hilgenfeld,R. (2001) C–H p-interaction ... a new way of thinking about the functional role of the former ionizable aromatic amino acid. The pH optimum mechanism in API results from two things: (a) positively charged His210 interacts with...

Ngày tải lên: 21/02/2014, 03:20

... respectively. By introducing an Ala residue in the place of Gly it is expected that the conformational flexibility of the main chain can be constrained with a minimum perturba- tion of the local structure, ... our incomplete under- standing of the relation between enzyme properties and conformational flexibility limits the exploitation of the full potential of protein engineering in the redesign of psychro- philic ... the basis of side-chain packing criteria from a modelled structure of the enzyme resulted in restor- ation of the energy of activation to the levels of the native enzyme and in an increased stability...

Ngày tải lên: 22/02/2014, 04:20

... Factor Processing information (perceiving, retrieving, manipulating, transmitting) Compiling information, importance of 0.90 Seeing (DOT) 0.66 Work with complex things Combining information, importance of ... importance of 0.36 Practical problem solving Advising, importance of 0.86 Supervising nonemployees, importance of 0.64 Catering to people Planning and scheduling, amount of 0.83 Catering and serving, ... Catering to people Math, level of (DOT) 0.79 Math, level of 0.70 Quantitative information, extent of use 0.68 Coding and decoding, importance of 0.68 Oral information, extent of use 0.68 Talking...

Ngày tải lên: 06/03/2014, 05:20

... in DptF is GLDSV, indicating that this putative ACP domain is one of the few ACPs in which valine replaces isoleucine (I) or leucine (L) in the conserved sequence. To determine whether DptF is ... remains to be clarified whether all of the fatty acids activated by DptE can be incorpo- rated into the final product or whether there is an interfering specificity of the C III domain of the initia- tion ... buffer A in 15 min, followed by a linear gradient down to 5% buffer A in 2 min. 5% buffer A was held for an additional 2 min and followed by a linear gradient up to 95% buffer A in 6 min. Determination...

Ngày tải lên: 07/03/2014, 04:20

... clear whether or not H39 is dominantly tuning the V H ⁄ V L interaction of other Fvs, including HyHEL-10. In addition, the effect of the H39 mutation on antigen binding has not yet been analyzed. ... improved the antigen-binding affinity of Fv, similarly to the level of scFv (Table 2). Some single V H domains of anti-protein IgG, inclu- ding HyHEL-10 and D1.3, were known to retain the specificity ... determining the interdomain inter- action strength. Results Construction of an FR2 combinatorial library To investigate the possible relationship between anti- gen-binding affinity and V H ⁄ V L interaction...

Ngày tải lên: 07/03/2014, 12:20

... Cardie, Vincent Ng, David Pierce,Chris Buckley. Ex- amining the role of statistical and linguistic knowledge sources in a general-knowledge que stion answering sys- tem. In Proceedings of the 6th ... By relying on large, open-domain lin- guistic resources such as WordNet we enabled a more precise approach of searching and mining answers from large collections of texts. Evalua- tions indicate ... parse. By implementing our own version of the pub- licly available Collins parser (Collins, 1996), we also learned a dependency model that enables the mapping of parse trees into sets of binary rela- tions...

Ngày tải lên: 08/03/2014, 05:20

Ngày tải lên: 08/03/2014, 10:20

Ngày tải lên: 08/03/2014, 23:20

Ngày tải lên: 14/03/2014, 14:20