role in regulation of material and energy flux
Marine Chemical Ecology - Chapter 5 docx
Ngày tải lên :
12/08/2014, 00:21
... associating with holoplankton B ROLE IN REGULATION OF MATERIAL AND ENERGY FLUX Holoplankton, and to some extent meroplankton, are responsible for the regulation of material and energy flow in oceanic ... regions, McClintock and Baker12 examined a suite of Antarctic marine invertebrates with contrasting modes of reproduction These included the spawned eggs and larvae of a sea urchin and the intraovarian ... Vernon52 furthered the study of chemical defenses of echinoderm offspring by examining feeding-deterrent properties of the eggs and embryos of Antarctic sea stars, sea urchins, © 2001 by CRC Press...
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báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pptx
Ngày tải lên :
20/06/2014, 04:20
... BMP-2 maintained the mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc ... FGF-2 and BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in abundance of mineralization-related gene expression Mineralizing ... than FGF-2 in inducing new mineralization Materials and methods Materials We obtained GFs from Amgen, Thousand Oaks, CA FGF-2 and IGF-1 from R & D Systems, Minneapolis, MN TGFb, PDGF and dmPGE2...
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báo cáo hóa học:" The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization" pdf
Ngày tải lên :
20/06/2014, 07:20
... BMP-2 maintained the mineralizing RNA profile of igf-1, alp, and bmp-2 and significantly increased expression of other genes associated with mineralization like col1a1, fn, ilgf-1, noggin and oc ... FGF-2 and BMP-2, the yin and yang of mineralization: Contrast of effect of 24 hours of treatment with FGF-2 or BMP2 on fold increase in abundance of mineralization-related gene expression Mineralizing ... than FGF-2 in inducing new mineralization Materials and methods Materials We obtained GFs from Amgen, Thousand Oaks, CA FGF-2 and IGF-1 from R & D Systems, Minneapolis, MN TGFb, PDGF and dmPGE2...
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Báo cáo y học: " The role of IFN-γ in regulation of IFN-γ-inducible protein 10 (IP-10) expression in lung epithelial cell and peripheral blood mononuclear cell co-cultures" potx
Ngày tải lên :
12/08/2014, 15:21
... factor, interleukin or interferon, since previous studies have shown an inducible expression of IP-10 in a wide variety of tissues and cells under the influence of stimuli including interferons, interleukins, ... types including lung epithelial cells [5] Increased levels of both IP-10 and CXCR3 have been shown in patients with COPD, and subsequently this chemokine has been suggested to be involved in the inflammatory ... participated in the design of study and helped drafting of the manuscript; HC carried out experiments and performed statistical analysis, IK participated in the design of study and helped drafting of the...
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THE ROLE OF THE CTD PHOSPHATASE RTR1 AND POST-TRANSLATIONAL MODIFICATIONS IN REGULATION OF RNA POLYMERASE II
Ngày tải lên :
24/08/2014, 09:44
... staining and removal of proteins isolated in the gel, making this method both time consuming due to the need to excise individual spots of protein from the gel and limiting in the number of low ... Phosphorylated serine of yeast RNA polymerase II C-terminal domain S7 Serine of yeast RNA polymerase II C-terminal domain S7-P Phosphorylated serine of yeast RNA polymerase II C-terminal domain S cerevisiae ... repeats (described in detail below and reviewed in Heidemann, Hintermair, Voss, & Eick, 2013) In addition, modifications of interacting protein factors aid in the regulation of the transcription...
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Role of p73 in regulation of cell death specific role in mitotic cell death and potential regulation of caspase 2s
Ngày tải lên :
13/09/2015, 21:21
... with each other (Irwin and Kaelin, Jr., 2001) Each of them consists of a N-terminus trans-activation domain, a central DNA binding domain and a C-terminus regulatory domain (Illustration 1) All ... during mitosis, thus allowing chromatids to separate during anaphase towards opposing poles In the cells, the spindle checkpoint is kept active through the binding of inhibitory proteins BubR1 and ... ROLE OF P73 IN REGULATION OF CELL DEATH: SPECIFIC ROLE IN MITOTIC CELL DEATH AND POTENTIAL REGULATION OF CASPASE-2s TOH WEN HONG NATIONAL UNIVERSITY OF SINGAPORE 2007 ACKNOWLEDGMENT...
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Regulation of navigation and vessel-source pollution in the Northern Sea Route - Article 234 and state practice
Ngày tải lên :
01/11/2013, 09:20
... 15 of the Economic Zone Edict; Arts and 15 of the Environmental Edict; and Art 11 of the Decree of the Council of Ministers of the USSR, June 1990, ‘On Measures of Securing the Implementation of ... within the inland waters, territorial sea or EEZ adjoining the USSR northern coast and that it includes seaways suitable for guiding vessels in ice Due to the vagueness concerning leading in Article ... the mandatory prescription of leading in ‘other regions’, as well as from Article 7(1) which states that the NSRA will determine the beginning and end of the navigational period taking into account,...
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Tài liệu Báo cáo khoa học: Interaction between very-KIND Ras guanine exchange factor and microtubule-associated protein 2, and its role in dendrite growth – structure and function of the second kinase noncatalytic C-lobe domain docx
Ngày tải lên :
14/02/2014, 19:20
... and functional determinants of the protein–protein interaction between v-KIND and MAP2 (i.e the MAP2-binding core module in v-KIND and the v-KIND-binding core module in MAP2) across a range of ... in the KIND2 domain of v-KIND contain the core MAP2 binding module To identify the core MAP2-binding site within the KIND2 domain (amino acids 456–620), we analyzed five EGFP-fused KIND2 domain ... specific MAP2 binding resides within the 32 residues (amino acids 456–487) of the v-KIND KIND2 domain To examine whether the MAP2 binding core site of v-KIND binds to intact MAP2 protein, we coexpressed...
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Tài liệu Báo cáo khoa học: Roles of AP-2 transcription factors in the regulation of cartilage and skeletal development doc
Ngày tải lên :
16/02/2014, 09:20
... Functional role of AP-2a and AP-2e in chondrogenesis Overview of the differentiation stages during chondrogenesis and the involvement of transcription factors (henatoxylin and eosin-stained section of ... an increase in apoptosis [73] The authors of this study ascribe the regulation of outgrowth of limb buds and patterning of the digits to the chicken AP-2 The role of AP-2a was further studied in ... tumorigenesis and genetic diseases [47] Most analyses of the regulation of AP-2 and the interactions of the transcription factor with binding partners, as well as of the regulation of target gene...
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Báo cáo khoa học: Nuclear actin and actin-binding proteins in the regulation of transcription and gene expression docx
Ngày tải lên :
07/03/2014, 01:20
... contains an N-terminal domain harboring activation function 1, a central DNA-binding domain (DBD) and a C-terminal ligandbinding domain (LBD) containing activation function [67–70] Upon binding androgens, ... Actin and ABPs in transcription regulation B Zheng et al Table Role of nuclear actin-binding proteins interacting with the androgen receptor AR, androgen receptor; LBD, ligand-binding domain ... Direct a-actinin-2 ()) Bundling proteins Coactivator Supervillin NLS F-actin- and membraneassociated scaffolding protein Filamin NLS? Cross-linking proteins Filamin A NLS? Cross-linking proteins Transgelin...
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Báo cáo khoa học: Improvement of a monopartite ecdysone receptor gene switch and demonstration of its utility in regulation of transgene expression in plants pdf
Ngày tải lên :
16/03/2014, 06:20
... a highly flexible ligand-binding pocket [34] Mutational analysis in the LBD of CfEcR showed that the ligand-binding pocket of this EcR is highly flexible and that a single amino acid substitu- FEBS ... format generally consist of a transcriptional activation domain fused to a DNAbinding domain (DBD) and a ligand-binding domain (LBD) The chimeric gene (transactivation domain– DBD–LBD) is expressed ... microgram of protein shown are the mean of three replicates ± SD (A,C) Fold induction values (B,D) shown were calculated by dividing RLUÆlg)1 protein in the presence of ligand with RLUÆlg)1 protein in...
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Báo cáo khoa học: Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263 pdf
Ngày tải lên :
16/03/2014, 16:20
... COO– in the aminic part determines the position of the substrate within the S1¢-binding subsite O atoms of the main chain CO groups of LeuB387 and TrpB240, Od1 atom of AsnB241, and Oc atom of SerB386 ... atoms of the side chain d-guanidino group of this residue are involved in H-bonding as follows: Ne with the O atom of the main chain CO group of the TrpB240; Ng1 shares H bonding with O atom of ... residue could be involved both in catalysis and productive binding Graphic simulation of the interactions of arylamide substrates with the nucleophile binding subsite of PA indicates that the...
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Báo cáo khoa học: Huntington’s disease: roles of huntingtin-interacting protein 1 (HIP-1) and its molecular partner HIPPI in the regulation of apoptosis and transcription pptx
Ngày tải lên :
23/03/2014, 07:20
... ENTH domain of HIP-1 interacts with 3-phosphate containing inositol lipids and stabilizes the growth factor receptor tyrosine kinases by increasing their half-life following ligand induced endocytosis ... caspase-8-mediated pathway Rybp also interacts with ubiquitin-binding protein, procaspase-8, procaspase-10, and the HIPPI interactor apotin Interaction of HIPPI with Rybp is involved in murine neural development, ... HIP-1 interactor, is also involved in the Shh pathway by regulating Gli1 [37] The specific role of the Shh pathway in apoptosis or HD remains unknown Role of HIP-1 and HIPPI in transcriptional regulation...
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Báo cáo khoa học: Nuclear aggregates of polyamines are supramolecular structures that play a crucial role in genomic DNA protection and conformation potx
Ngày tải lên :
23/03/2014, 15:20
... modifications in the running properties of DNA [29] It has already been shown that single polyamines, mainly spermine, can modulate the DNA-binding properties of proteins, either increasing or diminishing ... upon incubation with increasing concentrations of single polyamines, starting from a concentration of lm polyamines, which is comparable to the concentration of polyamines forming NAPs in the ... Polyamine aggregates and DNA A body of evidence also indicates a role for polyamines in the regulation of gene expression [17] and in the cell cycle A correlation has been shown between increased...
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Báo cáo khoa học: Subcellular localization of yeast Sec14 homologues and their involvement in regulation of phospholipid turnover pptx
Ngày tải lên :
23/03/2014, 18:20
... form a network of proteins involved in the regulation of phospholipid metabolism Materials and methods Strains and culture conditions Yeast strains used in this study are listed in Table Cells ... integrative versions of C-terminal yEGFP fusions in frame with the ORF of interest Thus, yEGFP fusions were present in single copy in the genome and driven by the native promoter of the ORF of ... formation, indicating that Sec14p and the two homologues act as inhibitors of Plb1p in vivo This observation explains at least in part the low Plb1p activity in wild-type cells Interestingly, the inhibitory...
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Báo cáo Y học: Molecular characterization of MRG19 of Saccharomyces cerevisiae Implication in the regulation of galactose and nonfermentable carbon source utilization pdf
Ngày tải lên :
31/03/2014, 08:20
... monitored in MIG1 disruption (Fig 10, lane and 2) and wild-type (Fig 10, lane and 4) strains bearing multiple copies of MRG19 and grown in the presence of glucose (Fig 10, lane and 3) and glycerol ... gal80mrg19 strains Cells were grown to D600 of 0.5 in synthetic complete medium containing glycerol plus lactate and galactokinase activity was determined as described in Materials and methods MRG19 ... digesting with SalI and filling in with dNTPs and the resulting plasmid was named p19C-S This construct was expected to induce a protein of 49 kDa To determine subcellular localizations of Mrg19p,...
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material and energy balancing in the process industries 044482409x
Ngày tải lên :
01/04/2014, 10:15
... techniques of instrumenta- Material and Energy Balancing in the Process Industries tion design and optimisation for balancing purposes are now available (optimum measuring placement) Retrofitting and ... streams and of individual utilities are often independent and can be solved separately The classification of the stream (12) Material and Energy Balancing in the Process Industries is problematic In ... change of inventory in the tank (2) The incentive for setting up the balance in such system is regular monitoring of yields of main products and of specific consumption of utilities as a part of...
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Báo cáo vật lý: "Using of HPLC Analysis for Evaluation of Residual Monomer Content in Denture Base Material and Their Effect on Mechanical Properties" pptx
Ngày tải lên :
07/08/2014, 14:20
... comparison of 11 soft lining materials as a function of accelerated aging J Prosthetic Dentistry, 69, 114–119 Sanders, J.L, Levin, B & Reitz, P.V (1991) Comparison of the adaptation of acrylic resins ... strain and energy at break showed similar trends to that of tensile strength, with a decrease in stiffness and increase in ductility after a period of immersion in distilled water After analyzing ... attributed to the differences in curing methods and the brands of resin The results indicated a small statistically significant difference in favor of the water bath cure but clinically there were no...
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Báo cáo y học: "T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB: implications for rheumatoid arthritis" docx
Ngày tải lên :
09/08/2014, 08:23
... transcription factor NFκB, in order to gain insight into the regulation of chemokines at sites of inflammation Materials and methods Isolation of peripheral blood monocytes and lymphocytes Human monocytes ... RANTES and MCP-1 was unaffected (Figure 2c) This inverted pattern of utilization of NFκB for the T-cell contact-dependent induction of CC and CXC chemokines in monocytes is surprising and indicates ... factor binding elements in activating the interleukin-8 gene by pro-inflammatory cytokines J Biol Chem 1990, 265:21128-21133 42 Wood LD, Richmond A: Constitutive and cytokine-induced expression of...
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Báo cáo y học: "The role of codon selection in regulation of translation efficiency deduced from synthetic libraries" potx
Ngày tải lên :
09/08/2014, 22:23
... cost of expression Considering the cost of production, we looked at how introducing a new gene into the host cell influenced cell fitness The influence on fitness is, in general, a combination of ... usage of each codon, we identified UCA and CAU as the main codons contributing to the decrease in the fitness (see Materials and methods) The number of occurrences of the UCA codon, encoding serine, ... minimum value was identified It should be noted that since we are averaging the translation time in a window, an incorrect window size might in some cases result in incorrect identification of...
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