rhythm of the rain tab guitar pro
Tài liệu Deteriorating Access to Women’s Health Services in Texas: Potential Effects of the Women’s Health Program Affiliate Rule doc
Ngày tải lên :
13/02/2014, 06:20
... leading to the
termination of federal participation as early as November 1, 2012, thereby also eliminating 90%
of the funding for the program. The state has announced it would continue the program ... are the dominant providers of care in the WHP in their
markets, serving between half and four-fifths of the WHP patients in the five areas we
examined. If their patients must be served by other ... their locations, the nature and
quality of services provided, their reputations, the quality or attentiveness of staff, or for other
reasons.
The governor’s office has expressed the view that,...
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Tài liệu The Dynamic Retention Model for Air Force Officers- New Estimates and Policy Simulations of the Aviator Continuation Pay Program doc
Ngày tải lên :
17/02/2014, 23:20
... density function
of the unit normal distribution.
In this equation, the first term is the probability of staying multiplied by the value of stay-
ing, the second term is the probability of leaving ... depend on the spe-
cifics of the ACP program in effect during the period covered by the data used to estimate the
parameters of the model. (By specifics we mean, for example, the amount of the annual ... complexity of the model. e ACOL model devised by John Warner and
others provides many of the benefits of the DRM with considerably less computational burden.
So, before proceeding further in discussing...
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Tài liệu Project Management 2.0 – The Ultimate Benefits of the New Approach to Project Management docx
Ngày tải lên :
18/02/2014, 07:20
... his productivity and therefore curtailing the eciency of the rest
of the project team. The new wave of project management tools puts an emphasis on collabora-
tion and makes teams much more productive. ... California.
Project Management 2.0 –
The Ultimate Benets of the New Approach to Project Management
Project Management 2.0 –
The Ultimate Benets of the New Approach to Project Management
The term Enterprise ...
one hand, these factors lead to obsolete and useless project plans. On the other hand, they increase the
cost of errors in the initial design of the information hierarchy. The whole process becomes...
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Tài liệu Báo cáo khoa học: N-terminal extension of the yeast IA3 aspartic proteinase inhibitor relaxes the strict intrinsic selectivity ppt
Ngày tải lên :
19/02/2014, 00:20
... binding of this helical N-terminal seg-
ment of IA
3
. The E + I ô EI balance thus lies far to
the right and the addition of further residues at the
N-terminus or beyond residue 34 of the inhibitory
segment ... acids
on the surface of the enzyme, adjacent to the end of
the active site cleft where the N-terminal residues of
an inhibitory IA
3
helix would be expected to bind
(Fig. 3A). Extension of the inhibitory ... cyclised Q in place of the Met1 residue at the N-ter-
minus and (2) the C-terminal LE(H)
6
tag. It would
thus appear that appending the His-tag at the C-termi-
nus of the authentic S. castellii...
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Tài liệu Báo cáo khoa học: Salt-induced formation of the A-state of ferricytochrome c – effect of the anion charge on protein structure docx
Ngày tải lên :
19/02/2014, 05:20
... A-state even in the
absence of sulfate. Therefore, the kinetic progress
curve of Fig. 9B is expected to refer: (a) for the fast
phase, to the sulfate-induced destabilization of the HS
acid-denatured ... ligand X (the
other likely candidates, i.e. the lysines, are fully proto-
nated at pH 2.2) [18].
The heterogeneous character of the A-state promp-
ted us to investigate the effect of sulfate ... 2006 The Authors Journal compilation ê 2006 FEBS 5349
the positively charged clusters located on the protein
surface [11]. The distribution of lysines around the
heme crevice at the ‘front’ of the...
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Tài liệu Báo cáo khoa học: Interaction of the small heat shock protein with molecular mass 25 kDa (hsp25) with actin doc
Ngày tải lên :
20/02/2014, 23:20
... appearance of an additional peak at 7.65 mL
on the elution pro le. Increase of the temperature of
incubation was accompanied by the simultaneous increase
of the peak eluted at 7.65 mL and decrease of the ... electrophoresis. The
quantity of actin in the pellet was plotted against the total
quantity of actin in the sample.
Results
Heat denaturation of actin
Before starting the investigation of the HSP25–actin ... whereas
the 3D mutant of HSP25 slightly decreased the initial rate of
polymerization (15–25%, Fig. 7). The effect of HSP25
became negligible when parameter A of actin was close to
2.4. Increase of the...
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Tài liệu Báo cáo Y học: Proteolysis of bovine b-lactoglobulin during thermal treatment in subdenaturing conditions highlights some structural features of the temperature-modified protein and yields fragments with low immunoreactivity pptx
Ngày tải lên :
21/02/2014, 15:20
... [10].
Arg148 is not the only buried arginine in the structure of
BLG. The whole side chain of Arg40 (the other main point
of trypsin action) in the native structure of the protein is
deeply buried ... enzyme/BLG of 1 : 20 or of 1 : 10. Each BLG/protease mixture was then placed in a water bath thermostatted at 60 °C for the given amount
of time . At the end of the heat treatment the mixture ... decreasing the i mmunoreactivity
of the protein. Therefore, we also tested some of the
hydrolysis products obtained in this study for their immu-
noreactivity towards different sets of various...
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Tài liệu Báo cáo Y học: Identification and characterization of the Escherichia coli stress protein UP12, a putative in vivo substrate of GroEL pptx
Ngày tải lên :
22/02/2014, 07:20
... association of newly synthesized unfolded proteins with the
heat-shock protein GroEL. Nature 336, 254–257.
25. Lorimer, G.H. (1996) A quantitative assessment of the role of
the chaperonin proteins in protein ... For
comparison, the amount of GroEL was determined in the
same extracts using anti-GroEL Ig. It has been previously
shown that at the beginning of the stationary phase the rate
of synthesis of heat-shock proteins ... Scientific Services
Department of the Weizmann Institute by a single injection
of 150 lg of the purified protein, followed by two booster
shots of the same amount of protein at 2-week intervals.
Serum...
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Unfolding the Future of the Long War - Motivations, Prospects, and Implications for the U.S. Army docx
Ngày tải lên :
06/03/2014, 20:20
...
Unified Quest), on the topic of the long war, all of which have high-
lighted the difficulty of producing a single term capable of describing
the complex nature of the situation facing the United States. ... (PSYOPS). As the numbers grow,
2 Unfolding the Future of the Long War
consider it as the confluence of three sets of problems: those related to
the ideologies espoused by key adversaries in the conflict, ... hallmarks of Eisenhower’s policies during the Cold War. e
authors note further that the long war, like the Cold War, “takes time,”
and whether looking back on the 40 years of the Cold War, or further...
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Báo cáo khoa học: Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein pptx
Ngày tải lên :
07/03/2014, 06:20
... regions of
the Gag protein, or even other proteins). In the first
three examples, the second helix (as in CACW40A) was
the main element of secondary structure affected; in the
last example, the fourth ... than the average value of 0.86
found in other proteins [47], probably due to the long
loop in CACW40A, which is not very well hydrogen-
bonded to the rest of the structure [48].
None of the residues ... [31].
The residues with low NOE values (< 0.65) in
CACW40A were Ile9 (at the C-cap of the 3
10
-helix);
Tyr20 (at the beginning of the first helix); Lys26 and
Ala30 (at the C-cap of the first...
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Báo cáo khoa học: The catalysis of the SARS 3C-like protease is under extensive regulation by its extra domain doc
Ngày tải lên :
07/03/2014, 12:20
... residues
shown in the same way. The two Ser284–
Thr285–Ile286 loops from each of the pro-
tomers contact closely with each other to
constitute the bottom wall of the channel.
SARS 3C-like protease regulation ... that the extra domain in the coronavirus 3CL
protease might play roles in the enzymatic activity
[17,18]. Therefore, we initiated a domain dissection
approach to explore the function of the extra ... Fig. 2, the super-active mutant had an
apparent molecular mass almost identical to that of
the wild-type protease. However, the apparent molecu-
lar masses of the mutated proteases in the first...
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Báo cáo khoa học: Solution structure and backbone dynamics of the XPC-binding domain of the human DNA repair protein hHR23B docx
Ngày tải lên :
07/03/2014, 17:20
... structure. The quality of the struc-
tures was assessed using the refined energy terms and the
procheck program [37]. The surface electrostatic potential
distribution of the best overall model of XPCB–hHR23B
was ... further our knowledge with
respect to the mechanisms of action of these proteins,
it is crucial that we define the precise boundaries of
the STI1-homologous domain and compare the struc-
tures of ... [22] to examine in more detail the
flexible characteristics of the 275–284 segment of
hHR23B. Because of the high quality of our
15
N-HSQC spectra, 54 of the 58 protonated backbone
nitrogen atoms...
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Báo cáo khoa học: Functional fine-mapping and molecular modeling of a conserved loop epitope of the measles virus hemagglutinin protein pdf
Ngày tải lên :
08/03/2014, 08:20
... Similarly, the e-amino group of K387 could
form a salt bridge with the close carboxyl group of E395 and
further stabilize the peptide structure within the complex
with the antibody.
In the virus, the ... repertoire of antibodies, many of which may not
crossreact with the cognate protein. The natural structure of
the epitope can provide important guidelines for stabilizing
the peptide and improving ... exception)
the reactivity of all peptides exhibiting the binding motif.
More than 90% of the MV-HNE sequences found in the
databases were recognized by the neutralizing antibodies. In
the absence of...
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Báo cáo khoa học: NMR investigations of subunit c of the ATP synthase from Propionigenium modestum in chloroform/methanol/water (4 : 4 : 1) pot
Ngày tải lên :
08/03/2014, 10:20
... polymorphism of monomeric subunit c is
due to the interaction of the monomer with the artificial
environment lacking the stabilizing protein/protein contacts
within the ring. The undecameric c ring of the ... table,
and resist boiling in SDS for 5 min in the case of the
undecameric c ring of P. modestum [41]. This stability of the
ring makes structural flexibility rather unlikely, indicating
that the ... structure in the cystoplasmic
loop region was not apparent, and neither was there a break
in the a helix after the sodium ion-binding Glu65 residue.
The folding of subunit c of P. modestum in the organic
solvent...
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