... generated and expanded in vitro, might tip the balance and allow a true curative action in animal models of T1D [12], and much work is now directed to this area [20] Two recent studies in T1D and experimental ... withdrawal of anti-TNF-α [19] and thus, despite the dampening of joint inflammation and the reinstatement of fully functional CD4+CD25+ Treg, RA is still not cured These strands of evidence seem to ... series of studies in RA and other chronic autoimmune joint inflammatory diseases such as juvenile idiopathic arthritis and spondyloarthropathies, in which phenotype, distribution and functional studies...
... well-known risk factor for knee OA, and to a lesser degree for hip OA and hand OA, and probably acts through a change in load distribution in the knee [72], and systemic and local inflammatory ... with implicationsfor possible preventive treatments Bierma-Zeinstra and Verhagen Arthritis Research & Therapy 2011, 13:213 http://arthritis -research. com/content/13/2/213 Examples Lim and colleagues ... Centre for Chronic Conditions: Osteoarthritis: national clinical guideline forcareand management in adults London: Royal College of Physicians (UK); 2008 Rothwell PM: External validity of randomised...
... Biology and Medical Modelling 2006, 3:34 describe a computer simulation model that follows the formation and destruction of red blood cells (RBC) When standard assumptions about red cell formation and ... well-known process of RBC formation and destruction In so doing it shows the cause for hitherto unexplained observations [13] and predicts other clinical applications for routine blood analysis ... unexplained changes in the MCV and RDW-CV% and their clinical significance For simplicity, I have Page of (page number not for citation purposes) Theoretical Biology and Medical Modelling 2006,...
... Institute (IDI) in Kampala, Uganda, is a centre of excellence for HIV clinicalcare in the country, and maintains a large observational clinic database and a nested research cohort database on ... toxicities, and 18 (51%) and 11 (32%) of the 86 cited reasons for ART discontinuation and modification This gives a total error rate (comprising missing and incorrect items) of 67% for OIs, 52% for ART-related ... sub-Saharan Africa: implicationsforclinicalresearchand audit of care Journal of the International AIDS Society 2011 14:3 Submit your next manuscript to BioMed Central and take full advantage...
... of long-term care policy— financing, delivery, and workforce and identifies some of the major demographic and policy trends that will affect the demand for, and supply of, long-term care in the ... program for the poor, is the major public program covering long-term carefor the elderly andfor disabled people of all ages Despite the public’s tremendous interest in, and demand for, care in ... careand long-term care, such as home health careand subacute care, and efforts by states to substitute federal dollars for their own, Medicare now pays more of the costs than before The extent...
... cancer and local lymph node metastases: implicationsforclinical practice Journal of Experimental & Clinical Cancer Research 2011 30:30 Submit your next manuscript to BioMed Central and take ... therapeutic implicationsfor EGFR-targeted therapy strategy For NSCLC patients with metastases, determining the KRAS and EGFR mutation status in both primary and metastatic tumors may be critical for ... Diagnosis and Therapy Center of Lung Cancer, Tianjin 300060, China Authors’ contributions ZZ, CW and BS designed the study; LS and QZ performed experiments; LS and HL analyzed data and prepared...
... the prevalence and correlates of baseline HIV among those who are using the SIF This information is important to determine if the SIF could be used as a site for HIV related careand treatment ... providing a written informed consent, completing an interviewer-administered questionnaire and supplying a blood sample for HIV and hepatitis C testing All SEOSI participants provide informed consent ... a group of marginalized HIV infected individuals and therefore provides a unique opportunity to improve access to health services and HIV careand treatment [23] Furthermore, the capacity to prevent...
... Brand M, Hargreaves I, Heales S, Land J, Smolenski R, Davies NA, Cooper CE, Singer M: Association between mitochondrial dysfunction and severity and outcome of septic Page of (page number not for ... intrauterine growth rate and of low-birth-weight babies [45] Some of these changes have also been noted in South American Andean natives when compared with lowland residents [46] Among lowlanders ascending ... have been identified that confer performance benefits at high altitude Individuals homozygous for the Page of (page number not for citation purposes) Critical Care Vol 11 No Grocott et al insertion...
... (2003), European Unilateralism-Environmental Trade Barriers and the Rising Threat to Prosperity through Trade Website 16 http://www.census.gov/foreign-trade/statistics/index.html 17 http://vietnamese.vietnam.usembassy.gov/ambassador.html ... http://environment-safety.com/courses/EnvManagement/envStandards.htm 44.http://vea.gov.vn/vn/khoahoccongnghe/nhanxanh/gioithieunhansinthai/Pages 45 http://www.census.gov/foreign-trade 46.http://www.customs.gov.vn/Lists/TinHoatDong ... biết, Nxb Hà Nội Tiếng Anh 13 Adam McCarty (2001), Vietnam in ASEAN, Regional Intergration Process and Challenges, Hanoi 14 Damien J Neven (2000), Evaluating the effects of non-tariff barriers, University...
... into Efforts to Improve YRH By providing students with information and skills, sexuality education complements other efforts to provide quality reproductive health information and services and to ... youth-friendly services, and policy dialogue and advocacy School and livelihood opportunities complement and reinforce these approaches Table Effective YRH Program and Policy Actions Program and Policy Action ... nontreatment or delayed treatment; the need for early and effective treatment; the need to inform sexual partners and to treat them for STIs; and the effective methods for preventing STIs, especially correct...
... Congressional Research Service 12 China’s Economic Rise: History, Trends, Challenges, andImplicationsfor the U.S Foreign Direct Investment (FDI) in China China’s trade and investment reforms and incentives ... machinery and equipment and parts thereof; sound recorders and reproducers, television image and sound recorders and reproducers, and parts and accessories of such articles Congressional Research ... China, and discusses the implications of China’s economic rise for the United States Congressional Research Service China’s Economic Rise: History, Trends, Challenges, andImplicationsfor the...
... rigorous peer review to ensure high standards forresearch quality and objectivity Unfolding the Future of the Long War Motivations, Prospects, andImplicationsfor the U.S Army Christopher G Pernin, ... and Doctrine Command, Army Capability Integration Center, and was conducted within RAND Arroyo Center’s Force Development and Technology Program RAND Arroyo Center, part of the RAND Corporation, ... Szayna, and Derek Eaton for substantial feedback on interim ideas and products, and Lauren Caston for input into regular meetings Critical reviews of this document by Karl Mueller (of RAND) and Douglas...
... Data for China for years 1998 and 2001 are taken from Zhang and Liang (2006); Data for Vietnam are adapted from Nguyen Thi Kim Anh and Pham Thi Hoang Oanh (2007) for 1998, 2001 and 2004, and are ... forward rate allowed and the forward rate that would equate supply and demand Currency options were first introduced by Eximbank into Vietnam’s forex market in 2003 However, trading in this form ... of Foreign Exchange and Derivatives Market Activity 1998, Bank for International Payment, Basle —— (1999b), Market Liquidity: ResearchFindingsand Selected Policy Implication, Report, Bank for...
... T time slices, and N and are computed for each slice t Figure illustrates why such a modication is useful It depicts the frequency of the terms neural networks and expert system for each year ... the community, but would be necessary for an outsider to fully understand the discourse Take, for example, the terms backpropagation and hidden layer If a researcher of neural networks uses these ... words and phrases are coined or take on new meanings (Bauer, 1994; Jeffers and Lehiste, 1979) Below we describe an application in document clustering and point toward a theoretical framework for...
... Psychosocial influences on the development and course of coronary heart disease: Current status andimplicationsforresearchand practice Journal of Consulting andClinical Psychology, 70, 548-568 Spanier, ... Psychological and modifiable Sociodemographic and somewhat modifiable Biological and not modifiable Figure A gender and health model that exemplifies how health education researchers and practitioners ... men and women, disparity reduction (political, social, and economic) is ignored For example, gender is a powerful predictor of premature cardiovascular morbidity and mortality (Kannel, Hjortland,...
... Commission 32 Merging and Compilation Errors 34 VII Conclusions andImplications of the Findingsfor Consumers 37 A Credit scores and the information in credit reports vary ... statistics and distribution of score ranges for the files from this region, and from California specifically, were virtually identical to those for the entire sample Therefore, the researchers ... requirements for complete and accurate reporting of account information to credit repositories, and maintenance of consumer data by the repositories, with adequate oversight and penalties for non-compliance...
... that to be the case for most list and newsbrief documents andfor many transcripts Beyond news data, this holds for case law documents, many types of financial documents, and others matic Condensation ... acceptability rate for magazine LEADs climbed to 92.50/0, still lower than for any other source Document length was a factor for LEAD acceptability for the entire test corpus, but list, newsbrief and transcript ... rating and assigning attributes to the 2,727 test corpus documents and LEADs I would also like to thank Breck Baldwin, Afsar Parhizgar, David Schmeer and Paul Zhang for their comments and suggestions...
... published for prokaryotic ABC exporters are summarized in Table Resolution is highest for the ADP-bound form of Sav1866, and ˚ decreases to < A for the MsbA structures in the unliganded state (unliganded ... between TM helices andand between TM helices and provide noncovalent interactions with sites on the NBD These latter two linker regions, called intracellular loops and (ICL1 and ICL2) can both ... distances, residue accessibility and conformational transitions [38] For MsbA, several studies have attempted to determine the likelihood of the extreme conformations observed, and to verify the structures...
... organisms and organelles Some eukaryotes (land plants and various protists) use the multicomponent System I [also called the cytochrome c maturation (Ccm) system], and others (animals, fungi, and many ... in ball and stick representation, as are the methionine and histidine side chains that coordinate the heme iron, and the cysteine side chain that forms a thioether bond between heme and protein ... structure determination and refinement was collected at the Diamond Light Source, UK Integration and scaling were performed using denzo and scalepack [37] Subsequent data handling was carried out...
... R&D andresearch alone, the compound annual growth rates are positive Table Compound Annual Growth Rates for Federal Researchand Development andfor Federal Research Federal Outlays forResearch ... Congressional Research Service Economics and National Security: Issues andImplicationsfor U.S Policy overhead, gaining efficiency, and closing the Joint Forces Command in Norfolk, Virginia.19 (For further ... Specialist in Industry and Trade, Foreign Affairs, Defense, and Trade Division Congressional Research Service Economics and National Security: Issues andImplicationsfor U.S Policy “rich man’s”...