regulation of fatty acid binding protein expression

... were initially isolated, e.g livertype fatty acid- binding protein (L-FABP), brain-type fatty acid- binding protein (B-FABP), intestinal-type fatty acid- binding protein (I-FABP), etc However, this ... uptake of fatty acids across the plasma membrane and transport to various subcellular organelles, (b) modulation of the activity of enzymes involved in fatty acid metabolism, (c) protection of enzymes ... been given a variety of names, such as ileal lipid -binding protein, intestinal 15 kDa protein, ileal bile acid- binding protein and gastrotropin, reflecting the speculations of authors on its intracellular...

Ngày tải lên: 07/03/2014, 06:20

... temporal expression of the B-FABP gene reported here (Fig 4C) and our previous report of its expression in the periventricular grey zone of the optic tectum of adult zebrafish brain, a site of neurogenesis ... (1990) Essential fatty acids in membrane: physical properties and function Biochem Soc Trans 18, 779–781 Ntambi, J.M & Bene, H (2001) Polyunsaturated fatty acid regulation of gene expression J Mol ... functions of intracellular fatty acid- binding proteins Biochim Biophys Acta 1391, 287–306 Hertzel, A.V & Bernlohr, D.A (2000) The mammalian fatty acidbinding protein multigene family: molecular...

Ngày tải lên: 31/03/2014, 07:20

... inhibitor/heart -fatty acid- binding protein Gene 147, 237–242 10 Prinsen, C.F & Veerkamp, J.H (1996) Fatty acid binding and conformational stability of mutants of human muscle fatty acidbinding protein ... differential expression of a heart-type fatty acid- binding protein in the mummichog (Fundulus heteroclitus) Mar Environ Res 54, 379–383 45 Glatz, J.F & Vusse, G.J (1996) Cellular fatty acid- binding proteins: ... distribution of rat heart fatty acid binding protein mRNA: identical forms in heart and skeletal muscle Biochemistry 26, 7900–7904 39 Miller, W.C., Hickson, R.C & Bass, N.M (1988) Fatty acid binding proteins...

Ngày tải lên: 31/03/2014, 07:20

... Moerkerk HTB (1993) Fatty acidbinding protein and its relation to fatty acid oxidation Mol Cell Biochem 123, 101–106 15 Glatz JF & van der Vusse GJ (1996) Cellular fatty acidbinding proteins: their ... partial amino acid sequencing of an amphibian liver fatty acid binding protein Biochem Cell Biol 74, 109–115 ´ ´ ´ Cordoba OL, Sanchez EI & Santome JA (1999) The main fatty acid- binding protein in ... & Horio F (2009) Characterization of critical factors influencing gene expression of two types of fatty acid binding proteins (L-FABP and Lb-FABP) in the liver of birds Comp Biochem Physiol 154...

Ngày tải lên: 16/03/2014, 00:20

... involved in cellular fatty acid transport and utilization and compartmentalization of intracellular fatty acid storage, and also in fatty acidinduced regulation of gene expression (for review, ... the structure and function of fatty acid- binding proteins Cell Mol Life Sci 59, 1096–1116 Haunerland NH & Chisholm JM (1990) Fatty acid binding protein in flight muscle of the locust Schistocerca ... ligands are bound Binding of RA as well as of many fatty acids requires interaction with the side chains of a characteristic triad of conserved amino -acid residues in the ligand -binding hollow,...

Ngày tải lên: 23/03/2014, 10:21

... dynamics of fatty acid binding proteins will be overviewed in the following sections 1.1 Overview of the fatty acid binding protein family Fatty acid binding proteins form an intracellular protein ... holo-liver fatty acid binding protein 14 2.1.2.2 Structural studies on apo-liver fatty acid binding protein 15 2.1.3 A brief summary 15 2.2 Characterization of the dynamics of fatty acid binding proteins ... holo-intestinal fatty acid binding protein 11 2.1.1.2 Structural studies on apo-intestinal fatty acid binding protein 12 2.1.2 Structural studies on liver fatty acid binding protein 13 2.1.2.1...

Ngày tải lên: 11/09/2015, 09:59

... Fig Effect of leptin and progesterone on FAAH activity and expression (A) Effect of leptin on the activity of FAAH in human U937 and CHP100 cells and on the protein content and the mRNA of FAAH in ... activation of STAT3 signaling and/or via a progesterone receptor-mediated increase in nuclear levels of Ikaros, which in turn leads to up -regulation of a CRE-like site or of an Ikaros binding site, ... promoter also revealed a binding site for Ikaros, a member of the Kruppel family of Ôzinc fingerÕ DNAbinding proteins that acts as critical transcriptional regulator of lymphocyte ontogeny and...

Ngày tải lên: 30/03/2014, 15:20

... distribution of the brain-type fatty acid- binding protein (fabp7a) mRNA is localized to the pariventricular grey zone of the optic tectum of the adult zebrafish brain [24] Similar patterns of mRNA ... Perlmann T & Olson L (1999) Role of retinoids in the CNS: differential expression of retinoid binding proteins and receptors and evidence for presence of retinoic acid Eur J Neurosci 11, 407–416 ... Thisse B & Wright JM (2004) Differential expression of duplicated genes for brain-type fatty acid- binding proteins (fabp7a and fabp7b) during early development of the CNS in zebrafish (Danio rerio)...

Ngày tải lên: 16/03/2014, 22:20

... Nanoscale Res Lett (2009) 4:138–143 because of the fatty acid binding domain of BSA, which helps in the conjugation of stearic acid capped nanoparticle with the protein moiety [13] Also, serum albumin ... interaction of fatty acid binding domain of BSA molecule with stearic acid As the synthesized magnetic nanoparticle was capped with stearic acid molecule, it can effectively help in the formation of bioconjugate ... transport of nonesterified fatty acids in the circulation [14] Magnetic bioconjugate of stearic acid capped ultrafine maghemite nanoparticle with BSA molecule is quite advantageous in case of stability...

Ngày tải lên: 22/06/2014, 01:20

... containing a stretch of acidic amino acids [8], and acts as a translational enhancer Overexpression of PAIP1 increases the rate of mRNA translation in COS cells [9] Another regulatory protein, PAIP2, ... element -binding polypeptide AUF1 may control mRNA stability by binding to PABP1 [7] In light of the vital roles of PABP1 in mRNA metabolism, it is critical to control the expression of PABP1 Expression ... 5¢-UTR of PABP1 mRNA [13,14] The ARS regulates the expression of PABP1 by a negative feedback mechanism In the presence of excess PABP1 in mammalian cells, PABP1 binds to the ARS element of its...

Ngày tải lên: 18/02/2014, 12:20

... promoted expression of Bcl-2 mRNA significantly According to these novel findings, the regulation of Bcl-2, Noxa and Bax expression would be involved in the possible signaling pathways of PACAP-evoked ... the BH3-only proteins (Bim, Bad, Bid, Bik, Bmf, Noxa, Puma and Hrk) To clarify the role of PACAPs in anti-apoptotic signaling pathways, the expression of mRNA for apoptosis-related proteins (Noxa ... slight increase of Bax mRNA (Fig 6A,D), suggesting the activation of apoptotic signaling However, the addition of PACAP27 led to a 41% and 43% decrease, respectively, in the expression of Noxa and...

Ngày tải lên: 16/03/2014, 04:20

... repeat element binding protein: cellular nucleic acid binding protein Virus Res 58, 73–82 Flink IL & Morkin E (1995) Alternatively processed isoforms of cellular nucleic acid- binding protein interact ... nucleic acid- binding protein (CNBP) gene in Xenopus laevis Gene 241, 35–43 21 Flink IL, Blitz I & Morkin E (1998) Characterization of cellular nucleic acid binding protein from Xenopus laevis: expression ... Analysis of the nucleic acid annealing activities of nucleocapsid protein from HIV-1 Nucleic Acids Res 23, 2434–2441 34 Rein A, Henderson LE & Levin JG (1998) Nucleic-acidchaperone activity of retroviral...

Ngày tải lên: 16/03/2014, 12:20

... insufficient DNA -binding of the drug, increased DNA-repair of cisplatin adducts and failure of induction of apoptosis, reviewed in [2,5,7] The RNA binding motif protein 3, RBM3, is a glycine rich protein ... by down -regulation of RBM3 (Additional file 1B-C) Cisplatin treatment did not affect RBM3 protein expression or the siRNA mediated down -regulation of RBM3 (Additional file 2) The effects of RBM3 ... favourable prognostic impact of RBM3 expression in EOC was demonstrated at both the gene expression and protein levels in two relatively large independent cohorts RBM3 protein expression was assessed...

Ngày tải lên: 18/06/2014, 16:20

... and protein levels as well as in DNA binding Time-course analyses have revealed that upregulation of the C/EBPb activating isoforms Full/LAP often precedes upregulation of the inhibitory isoform ... adjusted volume feature of Quantity One 5.4.1 software (Bio-Rad) Data are expressed as the ratio between the intensity of the protein of interest band and the loading control protein band (b-actin) ... regulates pro-inflammatory gene expression in glial activation To study the involvement of C/EBPb in the regulation of pro-inflammatory gene expression, mRNA levels of NOS2, IL-1b, IL-6 and TNFa...

Ngày tải lên: 19/06/2014, 22:20

... retinaldehyde binding protein J Biol Chem 2003, 278:12390-12396 Budhu AS, Noy N: Direct channeling of retinoic acid between cellular retinoic acid- binding protein II and retinoic acid receptor ... 75:200-212 Boylan JF, Gudas LJ: Overexpression of the cellular retinoic acid binding protein- I (CRABP-I) results in a reduction in differentiation-specific gene expression in F9 teratocarcinoma ... signalling in the absence of CRABP2 [9,46,47] In aggregate, increased expression of Crabp2 is generally linked to activation of the retinoid pathway either directly, because expression of Crabp2 is regulated...

Ngày tải lên: 09/08/2014, 01:22

... mechanism of rapid degradation of LHR mRNA led to the identification of a novel RNA binding protein that mediates the post-transcriptional regulation of LHR mRNA in the ovary [10–12] This protein, ... and RNA binding site of IRP1 Many of the amino acids at the active site of aconitase were found to serve both catalytic and RNA binding functions, thus showing the functional plasticity of these ... Active site of LRBP involved in LHR mRNA recognition A K Nair et al 3398 to LHR mRNA and for suppression of its translation Results LHR mRNA binding activity of rat MVK mutant proteins No protein...

Ngày tải lên: 16/03/2014, 06:20

... In addition to the protein peaks, they also contained IAEDANS or IANBD bands, indicative of covalent binding of the dyes [19] Binding activities of Ag-NPA-1 Binding of fatty acids, retinol and ... lipidbinding proteins of oad their ligands to membranes: differential mechanisms of fatty acid transfer by the ABA-1 polyprotein allergen and Ov-FAR-1 proteins of nematodes and Sj-FABPc of schistosomes ... galli fatty acid- binding protein, a member of the nematode polyprotein allergens family Eur J Biochem 261, 569–576 13 Wilton DC (1990) The fatty acid analogue 11-(dansylamino) undecanoic acid...

Ngày tải lên: 16/03/2014, 18:20

... of the three CP modules of the betachain of C4BP and evaluation of potential sites of interaction with protein S Protein Eng 8, 1253–1258 Dahlback, B (1983) Purification of human C4b -binding protein ... Inhibition of protein Ca cofactor function of ¨ human and bovine protein S by C4b -binding protein J Biol Chem 261, 12022–12027 Schwalbe, R., Dahlback, B., Hillarp, A & Nelsestuen, G (1990) ¨ Assembly of ... FEBS 2003 The role of CCP2 of the C4BP b-chain in binding of protein S (Eur J Biochem 270) 97 Fig SDS/PAGE analysis of recombinant C4BP b-chain CCP1-2 (A) Indicated recombinant proteins (wild-type...

Ngày tải lên: 17/03/2014, 09:20

... phosphorylation of proteins including hyaluronan binding protein Cell Mol Biol Res 41, 467±476 Rao, C.M., Deb, T.B & Datta, K (1996) Hyaluronic acid induced hyaluronic acid binding protein phosphorylation ... representative of three similar sets of experiment (D) Scatchard plot analysis of the anity of di€erent oligomeric forms of HABP1 for hyaluronan (s) Trimer; (d) hexamer and mouse [22] Oxidation of noncovalent ... molecular mass of 68 kDa, and the protein of the minor peak has a molecular mass of 25 kDa, corresponding to the monomeric size of HABP1 Gel-permeation experiments carried out in the presence of 0.1%...

Ngày tải lên: 17/03/2014, 17:20

... simulations of intestinal fatty acid binding protein Biophys J 90, 1535–1545 Thumser AE & Storch J (2006) Characterization of a BODIPY-labeled fluorescent fatty acid analogue Binding to fatty acid- binding ... Intracellular fatty acid trafficking and the role of cytosolic lipid binding proteins Prog Lipid Res 28, 245–272 Bass N, Manning JA & Ockner RK (1985) Regulation of the biosynthesis of two distinct fatty acid- binding ... related to fatty acid binding proteins Mol Biochem Parasitol 58, 215–222 Esteves A, Portillo V & Ehrlich R (2003) Genomic structure and expression of a gene coding for a new fatty acid binding protein...

Ngày tải lên: 23/03/2014, 07:20