recommendations for the safe handling of perchloric acid
CRC handbook of laboratory Safety - Chapter 4 docx
... provided to the employees to inform them of the contents and location of the CHP for the facility, the location and means of accessing chemical information, such as Material Safety Data Sheets, the standard ... the exception of the requirements for MSDSs and similar information sources, the provisions of the CHP apply If the chemical is produced for a user outside the laboratory, the provisions of the ... committee C The CHO for the organization This person could be the head of the Health and Safety department or the chairperson of the chemical hygiene committee However, neither of these persons would...
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Báo cáo khoa học: New members of the brachyurins family in lobster include a trypsin-like enzyme with amino acid substitutions in the substrate-binding pocket potx
... 27 acids ⁄ 14 acids ⁄ 14 acids ⁄ 14 acids ⁄ 14 acids ⁄ 14 amino amino amino amino amino 15 15 15 15 15 acids acids acids acids acids amino amino amino amino amino acids ⁄ 237 acids ⁄ 237 acids ... numbering) is involved in the formation of a salt bridge with the N-terminal Ile of the mature enzyme for completing the formation of Fig Distribution of charged amino acids in Panulirus argus ... from the 3¢ UTR region of PaTry2 However, the 3¢ UTR sequence of PaTry4 differed to those of the other trypsins in more than 36% of its nucleotides All ORFs started at the first ATG codon of the...
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Báo cáo khoa học: Polysaccharide binding sites in hyaluronate lyase – crystal structures of native phage–encoded hyaluronate lyase and its complexes with ascorbic acid and lactose docx
... structures The overall folding of the protein chain of HylP2 (Fig 4A) is similar to ˚ that of HylP1 with an rmsd shift of 0.6 A for the Ca atoms The view from the top shows the locations of the two ... positions of LysC179 and GluB167 and the scope of conformational changes of their side chains (Fig 2A) On moving further from the N-terminus and towards the C-terminus, there is another cluster of residues ... (Fig 1A) inhibits the activity of HylP2 The structure of the complex of HylP2 with ascorbic acid shows that three molecules of ascorbic acid bind to HylP2 trimer at each one of the three concave...
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Báo cáo sinh học: " Rotavirus nonstructural protein 1 antagonizes innate immune response by interacting with retinoic acid inducible gene I" pdf
... whereas, MDA5, another helicase for RNA virus recognition other than RIG-I, and MAVS, the downstream adaptor molecule for RIG-I, were fully competent to induce IFN activity in the presence of OSU NSP1 ... indicating that the reduction of RIG-I protein levels is not a result of transcription inhibition Further, we detected the levels of RIG-I protein in rotavirus infected cells Of more physiological ... BD) were cloned by PCR with the designed forward and reverse primers The PCR products were ligated into the sites of vector pEGFP-C1 Expression constructs for retinoic acid inducible gene I (RIG-I),...
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báo cáo hóa học:" Arthroscopic debridement of the osteoarthritic knee combined with hyaluronic acid (Orthovisc®) treatment: A case series and review of the literature" docx
... OA of the knee is extremely common, with some studies showing that OA of the knee occurs in at least 30% of people after the age of 50 years, and in 80% of people older than 75 years [4,5] Of the ... debridement of the and the medial Post arthroscopic debridement of the chondral lesions on the medial femoral condyle and the medial tibia Page of (page number not for citation purposes) Journal of Orthopaedic ... labeled use of Hyaluronic Acid (HA) Orthovisc® for treatment of pain due to OA of the knee involves a series of ml (30 mg of HA: 15 mg/ml) injections weekly in the clinic over a span of three weeks...
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báo cáo hóa học:" Stabilization of mid-sized silicon nanoparticles by functionalization with acrylic acid" pptx
... in the work of Rosso-Vasic et al [23] XPS measurements were performed to unambiguously prove the formation of a covalent bond between the acrylic acid and the silicon nanoparticles Observing the ... bonded to the surface via a covalent Si-C bond, resulting from the reaction of the hydrogen-terminated silicon surface and the alkene group of the acrylic acid This, together with the missing ... Afterwards, the particles were filtered again, washed with chloroform, and centrifuged out of chloroform dispersion Finally, the particles were dried overnight To alleviate particle handling in the X-ray...
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Titration with Oxalic Acid ppsx
... Question of the pre-lab to determine the number of moles of base needed to neutralize the calculated number of moles of oxalic acid c Calculate the molar concentration of based used Does the amount of ... through the tip to clear the buret tip of air Stop between 0.0 and 2.0 mL Remove the hanging drop at the tip by touching the tip to the inside of the waste beaker Read the initial volume in the buret ... Math Problems) Determine the molarity of the unknown sodium hydroxide solution as follow a Calculate the number of moles of oxalic acid used for NaOH, using the molar mass of H2C2O4 • 2H2O b Use...
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Báo cáo y học: "Safety and Effectiveness of two treatment regimes with tranexamic acid to minimize inflammatory response in elective cardiopulmonary bypass patients: a randomized double-blind, dosedependent, phase IV clinical trial." pdf
... on the expected incidence rate of IR with 80 mg/kg In the present study, we hypothesized that the double dose of TA would reduce the inflammatory response For expected incidences of 16.6% in the ... surgery For bleeding and D-dimer, correction for multiple variables was not carried out in the omnibus test because of the a priori known unidirectional nature of the effects of TA on these parameters ... observed in these first hours of the postoperative period, as found by our team in a previous study [6] and by others [16,17] The presence of hyperthermia in the criteria used avoids the potential...
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Báo cáo y học: "Conventional or physicochemical approach in intensive care unit patients with metabolic acidos" ppsx
... Although the sensitivity of the AGcorr for the detection of hyperlactatemia increased to 100%, it was not specific (11%) Therefore, determination of the (corrected) AG is not a good substitute for the ... stay, the hospital stay and the incidence of complications Furthermore, the use of Ringer’s lactate has been associated with postoperative hypercapnic acidosis and hyponatremia [17] Therefore, the ... between the AGcorr and the SIG (r2 = 0.934, P < 0.001; Fig 1) The bias was 1.86 and the precision was 0.96 The limits of agreement were therefore –0.06 and 3.78 (Fig 2) Discussion The main finding of...
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Báo cáo khoa học: "Circulating anions usually associated with the Krebs cycle in patients with metabolic acidosis" potx
... ultrafiltrate acids from that observed in the control group were seen in the patients within the lactic acidosis and 'unexplained acidosis' groups In these two groups, the concentrations of most of the acids ... explain how the 'missing' ions in the elevated anion gap may be generated These include the choice of fluid used for resuscitation, the effects of hypoproteinaemia or the presence of other metabolites ... Discussion The consequences of metabolic acidosis can be catastrophic and a considerable body of literature highlights the poor outlook in patients where lactic acid is the principal component of the acidaemia...
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Báo cáo y học: "Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication" docx
... production We hypothesize that inhibition of mitochondrial respiration is responsible for the development of lactic acidosis during metformin or phenformin intoxication If our hypothesis is correct, ... when the analysis was restricted to the patients equipped with a pulmonary artery catheter, the major findings of the study remained valid Third, the respiratory quotient - the ratio between the ... metformin or phenformin accumulation, the inhibition of mitochondrial respiration is so strong that the production of lactate (by the liver and, probably, other tissues) increases above the residual...
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Iron(III) and copper(II) complexes bearing 8 quinolinol with amino acids mixed ligands synthesis, characterization and antibacterial investigation
... that formation of chelates metal ions increases the lipophilicity of the bioactive compounds through diverse array of biological oxidation–reduction mechanism for the effective permeability of the ... chelating concept that the release of electron(s) from the transition metals decreases the polarizability of the metal which has been proven to enhance the cytoxicity of the metal complex (Khalafi-Neshad ... donation of the standard bacterial strains and Prof Shinya Hayami of Kumamoto University, Japan for the use of magnetic measurements instrument S.A.A (P13340) is thankful to Japan Society for the...
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Enhanced transdermal delivery with fatty acids and electroporation
... applied to the skin, the steady state systematic dosage may not be reached for some time because of absorption of the drug in the skin For the majority of drugs, a plot of drug release from the device ... measure the uptake of each formulation or fatty acid by the SC FTIR is used to investigate the effect of fatty acids in different solvents on the biophysical parameters of the SC by monitoring the ... (D) TREATED WITH OLEIC ACID IN MO THE LOCATION OF THE DASHED LINES CORRESPONDS WITH THE VIBRATION FREQUENCY OF THE ASYMMETRIC AND SYMMETRIC PEAKS OF THE LIPIDS IN THE SC BEFORE DELIPIDISATION ...
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AN0559 optimizing serial bus operations with proper write cycle times
... byte for the non-optimized case To poll the 93LCXX series products, the chip select is pulled high after the write cycle commences, and the data out line is read for the ready/busy status If the ... may be engaged in theft of intellectual property Microchip is willing to work with the customer who is concerned about the integrity of their code Neither Microchip nor any other semiconductor ... breach the code protection feature All of these methods, to our knowledge, require using the PICmicro microcontroller in a manner outside the operating specifications contained in the data sheet The...
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The Transformation of Escherichia coli with Deoxyribonucleic Acid isolated from Bacteriophage Adgt
... kinaseless mutant The conditions of the experiment were those of the standard transformation assay described at the end of the next section Therefore, Adg DNA, like Adg, carries both the gene for galactose ... from the >tdg DNA The EMB plates are therefore scored for the total number of galactose-positive colonies and for the number of galactose-positive colonies with a halo of lysis The results of this ... unlikely, therefore, that inactivation is due to other enzymes contaminating the preparation of DNase TRANSFORMATION OF E COLI 405 The kinetics of inactivation of transforming activity and of decrease...
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Tài liệu Báo cáo khoa học: Helicobacter pylori acidic stress response factor HP1286 is a YceI homolog with new binding specificity pdf
... rmsd between the two structures is 1.54 A for the superposition of 155 amino acids of the monomer, and ˚ 1.51 A for the superposition of 303 amino acids of the dimer (Fig 2A) Significant differences ... indicates that, despite the fact that the three proteins belong to the YceI-like family from the point of view of the amino acid sequence and of the 3D structure, they must differ in their physiological ... head of the ligand is close to the open end of the cavity, which is accessible to the solvent The amidic group of the ligand interacts with side chain atoms of Arg80, but residues surrounding the...
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Tài liệu Báo cáo khoa học: Suppressed catalytic efficiency of plasmin in the presence of long-chain fatty acids Identification of kinetic parameters from continuous enzymatic assay with Monte Carlo simulation ppt
... are the rate constants for inactivation of the respective forms of the enzyme In independent measurements with fatty acids we showed that the inactivation of free plasmin for the duration of the ... adequate for the final evaluation of the kinetic parameters in the presence of stearate Evaluation of kinetic parameters Fig Comparison of three models for the catalytic action of plasmin in the presence ... decrease of plasmin activity in the course of the assay in the presence of stearate (Table 1) The good fit of Model III progress curves to the experimental data supports the concept that in the presence...
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Tài liệu Báo cáo khoa học: Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-D-glyceric acid Selective inhibition by structure-based design docx
... preincubation of the enzyme with the compound for followed by addition of the reaction mixture to start the reaction A possible effect of the inhibitors on the absorbance of NADH was checked The concentration ... Thr167 of the protein and the amino group of compound No other inhibitor offered such an interaction For compounds 5–8, the interaction of one phosphonate group at the Ps site may be responsible for ... proteins These Kd values actually represent the ligand affinities for a nonactive conformation of the enzyme in the absence of substrate and cofactor Molecular modelling To elucidate the different...
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