recognition and removal of bulky dna lesions by the nucleotide excision repair system
Báo cáo hóa học: " Effects of rehydration nutrients on H2S metabolism and formation of volatile sulfur compounds by the wine yeast VL3" docx
Ngày tải lên :
20/06/2014, 23:20
... previous hypothesis of distinct effects for each of the treatments and further suggest the presence of an additional nutrient factor regulating the formation of H2S Confirmation of the microarray ... observations at the sampling point where the addition of rehydration nutrients induced the formation of H2S while the addition of DAP delayed it Page of 11 (Figure 1c) Nonetheless, these results ... pathway (Figure 2c) Addition of DAP, on the other hand, upregulated approximately 67% of the genes involved in sulfate assimilation and the synthesis of the sulfur-containing amino acids (Figure...
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The Income Statement and Statement of Cash Flows4Copyright © 2007 by The McGraw-Hill Companies, docx
Ngày tải lên :
29/06/2014, 03:20
... in the operations of the component after the disposal transaction 4-24 Discontinued Operations Reporting for Components Sold Operating income or loss of the component from the beginning of the ... reporting period to the disposal date Gain or loss on the disposal of the component Reporting for Components Held For Sale Operating income or loss of the component from the beginning of the reporting ... beginning of the reporting period to the end of the reporting period An “impairment loss” if the carrying value of the assets of the component is more than the fair value minus cost to sell 4-25...
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Báo cáo y học: "Genetic polymorphisms in the nucleotide excision repair pathway and lung cancer risk: A meta-analysis"
Ngày tải lên :
31/10/2012, 14:59
... counteracts the carcinogenic effects of DNA damage is DNA repair As stated earlier, there are several known pathways of DNA repair, all of which act to remove DNA lesions and prevent mutations, thereby ... lack of these bases leads to read-through of the start codon [63] However, there has been no precise explanation of the mechanism by which the recognition of the start codon is aided by a purine ... because of their inability to repair UV-induced DNA lesions These clinical findings are associated with cellular defects, including hypersensitivity to killing and the mutagenic effects of UV and the...
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Báo cáo khoa học: Substrate recognition and ®delity of strand joining by an archaeal DNA ligase docx
Ngày tải lên :
17/03/2014, 11:20
... concentration of 20 lM, the substrates, L -DNA( 40) and R -DNA( 30), were consumed almost completely and ligated by 0.2 lM of LigTk The concentrations of L -DNA( 40) and R -DNA( 30) were lM each and considerably ... length of oligonucleotides recognized by LigTk as DNA substrates At 80 °C, LigTk could ligate oligonucleotides of nine nucleotides or more as L -DNA with an R -DNA of 30 nucleotides, and an R -DNA of ... (L -DNA and R -DNA) and a complementary oligonucleotide (T -DNA) A phosphate group was present at the 5¢ terminus of R -DNA Deletions, insertions and mutations were introduced to the L -DNA( 40), R -DNA( 30)...
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Báo cáo khoa học: DNA mediated disassembly of hRad51 and hRad52 proteins and recruitment of hRad51 to ssDNA by hRad52 pot
Ngày tải lên :
16/03/2014, 14:20
... ssDNA The results described in this study help us to understand the transitions associated with the oligomeric states of hRad51 and hRad52 proteins in the presence of ssDNA and relate them to their ... concentrations of DNA as described in (A) in the absence of any nucleotide cofactors and later subjected to centrifugation and the resulting pellet and supernatant were analysed by SDS PAGE followed by silver ... to study the effect of DNA on hydrodynamic radius (Rh) of hRad51 hRad51 (1 lM) was incubated with 0, 1, 3, and lM of oligo PUC+ (in the absence of any nucleotide cofactor) followed by the measurement...
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Photodegradation and removal of phenol and phenolic derivatives from petroleum refinery wastewater using nanoparticles of TiO2
Ngày tải lên :
05/09/2013, 17:03
... of the pollutant and also the size of aggregates it forms To study the pH effect, the pH was varied from to 10 and at typical times of 60 and 120 which are illustrated in Figure The maximum removal ... of the reactor and discharging to the bottom just below the lamp for the well-mixing and fluidizing of nanoparticles of catalyst along the quartz tube It was not expected that a single pass of ... pH=6.5 and T=303 K 3.3 Effect of pH An important parameter in the photocatalysis is the pH reaction, since it determines the surface charge properties of the photocatalyst and therefore the adsorption...
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Tài liệu Prevalence of respiratory symptoms and cases suspicious for tuberculosis among public health clinic patients in Afghanistan, 2005–2006: Perspectives on recognition and referral of tuberculosis cases doc
Ngày tải lên :
15/02/2014, 13:20
... cases and those with other respiratory symptoms (power = 80, two-sided alpha = 0.05) The study was approved by the Ethical Review Board of the Ministry of Public Health, Afghanistan, and the ª ... staining and interpretation by the Kabul-based reference laboratory (German Medical Services, Darwaze Lahori, Kabul), and the last for cases of loss ⁄ breakage At the time of the study, there was ... Institutional Review Boards of the Johns Hopkins Bloomberg School of Public Health and the University of California, San Diego Two male–female respiratory survey teams of medical professionals completed...
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Tài liệu Báo cáo khoa học: Induction of uPA gene expression by the blockage of E-cadherin via Src- and Shc-dependent Erk signaling docx
Ngày tải lên :
19/02/2014, 05:20
... addition to the loss of cell–cell adhesion, involves degradation of the extracellular matrix and release of cells from the constraints of cell–cell and cell–matrix interaction MMPs and urokinase-type ... Src- and Shc-dependent and resulted in enhanced expression of the uPA gene and, to a lesser extent, of the MMP-9 gene (data not shown) Disruption of cell–cell adhesion by calcium chelation Loss of ... re-establishment of cell–cell adhesion However, the duration of this activation is much shorter and the underlying molecular mechanisms of the two systems are different While Erk activation by the establishment...
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Tài liệu Báo cáo Y học: The solution structure and activation of visual arrestin studied by small-angle X-ray scattering pot
Ngày tải lên :
22/02/2014, 07:20
... by us Neither of these parameters are within the range of our experimental observations, and therefore the predominant species in solution are the monomer and dimer Additional evidence that the ... kDa and the forward scattering of the monomer, I(0)M to the appropriate value, as determined using a BSA standard The only variable fitted was the value for Kd To account for the formation of large ... for the contrast of the hydration shell and average displaced solvent volume per atomic group The target function for CRYSOL is the v value, which is a measure of the agreement between the theoretical...
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Báo cáo khoa học: Versatile regulation of multisite protein phosphorylation by the order of phosphate processing and protein–protein interactions pptx
Ngày tải lên :
07/03/2014, 10:20
... thermodynamic aspects of complex multisite phosphorylation on the one hand, and the specific and versatile regulation of protein activation required in signaling pathways on the other Results Mathematical ... protein an ¼ ð3Þ These account for both enzyme–target binding and the catalysis K and P denote the free concentrations of kinase and phosphatase, respectively, and Ln and Qn are the respective ... directly inhibited by the phosphatase (and dephosphorylation by the kinase) due to competition of the two enzymes for the target Indeed, there is experimental evidence for kinases and phosphatases...
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Temperature dependence of morphology and diameter of silicon nanowires synthesized by laser ablation
Ngày tải lên :
16/03/2014, 15:09
... in the formation of chains of silicon nanoparticles The formation of the kinks of silicon nanoparticle chains resulted from a change of growth direction of the SiNWs We examined the kinks by ... dependence of the morphology of SiNWs synthesized by laser ablation In this Letter, we present the results on this project Our results show that the morphology and diameter of SiNWs synthesized by laser ... to renucleation of the crystal silicon in growth process On the other hand, the diameter of each branch of the octopus-shaped nanowires decreases gradually as the distance from the tip increases...
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The Wit And Humor Of America Volume Ii By Various, Marshall P. Wilder pdf
Ngày tải lên :
16/03/2014, 15:20
... acknowledged the deities of Athens But the seal of their shame is their own smile at their early dreams, and the high hopes of their boyhood, their sneering infidelity of simplicity, their skepticism of ... of the waking sight, even, of the then sleeping mamas, the daughters whirled in the close embrace of partners who had brought down bottles of champagne from the supper-room, and put them by the ... explained They had been boys once, all of them, fresh and frank-hearted, and full of a noble ambition They had read and pondered the histories of great men; how they resolved, and struggled, and achieved...
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Pathophysiology and Complications of Diabetes Mellitus Edited by Oluwafemi O. Oguntibeju pptx
Ngày tải lên :
16/03/2014, 21:20
... layer formed by the intertwining apical dendrites of the granule cells and their afferents; (3) the polymorph layer in the hilus of the dentate gyrus containing the initial segments of the granule-cell ... accumulates In the hemoglobin, the preferential glycosylation site is the amino-terminal valine of the β chain of the globin (about 60% of glycosylated globin) Other sites are: lysin 66 and 17 of the β ... use of the work must explicitly identify the original source Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the...
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Recognition and Management of Pesticide Poisonings docx
Ngày tải lên :
17/03/2014, 10:20
... Statement: The administration of a cathartic alone has no role in the management of the poisoned patient There are no definite indications for the use of cathartics in the management of the poisoned ... management of poisonings and injuries caused by them Pesticide poisoning is a commonly under-diagnosed illness in America today Despite recommendations by the Institute of Medicine and others urging the ... better understand the relative risk of different pesticides However, the main purpose of these tables is to give physicians a sense of what types of cases they are most likely to see in their practice...
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synthesis and characterization of wo3 nanostructures prepared by an aged-hydrothermal method
Ngày tải lên :
20/03/2014, 13:08
... compounds and phases may exist It is thus anticipated that the formation of WO3 should have a strong dependence on the acid medium Furthermore, the aging time in solution and the hydrothermal treatment ... temperature by using ammonium metatungstate as tungsten source and without the presence of additives Experimental 2.1 Synthesis of WO3 Nanostructures WO3 nanostructures were synthesized by using ... characteristic of mesoporous materials above the relative pressure (P/Po) of 0.4 and specific surface area (SBET) values between 34 and 35 m2 (Table 2) The formation of a mesoporous material is due to the...
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Coeliac disease - Recognition and assessment of coeliac disease pdf
Ngày tải lên :
22/03/2014, 09:20
... recommendations, details of how they were developed, and reviews of the evidence they were based on A quick reference guide – a summary of the recommendations for healthcare professionals ‘Understanding NICE ... the patient and/ or guardian or carer, and informed by the summary of product characteristics of any drugs they are considering Implementation of this guidance is the responsibility of local commissioners ... responsibility of healthcare professionals to make decisions appropriate to the circumstances of the individual patient, in consultation with the patient and/ or guardian or carer, and informed by the summary...
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Báo cáo khoa học: Signalling and regulation of collagen I synthesis by ET-1 and TGF-b1 doc
Ngày tải lên :
23/03/2014, 11:20
... [47–49] and N-butanol [50–52] as specific inhibitors of PLD The inhibition of PC-PLC by D609 (Fig 5B) and inhibition of PLD by neomycin (Fig 5C) as well as by N-butanol (not shown) abolished the increase ... examined the possible DAG donors PLC-b, PC-PLC and PLD PLCb, a downstream effector of the Gaq [44] as well as of the bc subunit of Gai [45] was inhibited specifically by U73122 [46] Inhibiting PLC-b by ... also investigated the effects of combined ET-1 and TGF-b1 stimulation and of prolonged stimulation with respect to ET-receptor subtype expression and the induction of CTGF and TGF-b1 transcripts...
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Recognition and management of pesticide poisonings J. Routt Reigart, James R. Roberts docx
Ngày tải lên :
29/03/2014, 11:21
... Statement: The administration of a cathartic alone has no role in the management of the poisoned patient There are no definite indications for the use of cathartics in the management of the poisoned ... management of poisonings and injuries caused by them Pesticide poisoning is a commonly under-diagnosed illness in America today Despite recommendations by the Institute of Medicine and others urging the ... better understand the relative risk of different pesticides However, the main purpose of these tables is to give physicians a sense of what types of cases they are most likely to see in their practice...
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Báo cáo khoa học: Insights into the activation of brain serine racemase by the multi-PDZ domain glutamate receptor interacting protein, divalent cations and ATP ppt
Ngày tải lên :
30/03/2014, 03:20
... DNA sequencing Then, they were double digested with NdeI plus SalI and ligated into the corresponding sites of pCWori In all cases, the hexa-His was at the N-terminal end of the protein and the ... GAP2 together with PDZ7 Interestingly, in the absence of additional ATP, the activation induced by the presence of the PDZ4PDZ5-PDZ6-GAP2-PDZ7-end of GRIP reached the highest value The conformational ... referred to as GAP1 and GAP2 (Fig 2A) Binding of GRIP to SR occurs through the direct interaction of the PDZ6 domain of GRIP and the final four amino acids of SR [12] We performed the recombinant...
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