... ofthe c ring, respectively The C-terminal helices show a clear handedness, and two ofthe rings face inthe opposite direction inthe membrane to the other two, forming the same pattern as in ... ion-binding site Therefore, the c ring of A woodii has only 10 membrane-buried negative charges that are essential for binding the ion and also for the rotational mechanism ofthe ring The c ring ... inthe AFM surface representation of Fig 2A By comparison with the 3D structure ofthe I tartaricus c ring [24], the black rings represent the view from the cytoplasm (open rings in AFM) and the...
... method of localizing biologically active molecules in defined area on the electrodes Also the use of conducting polymers inthe area of bioanalytical sciences is of great interest since their biocompatibility ... quantify the amount of protein binding sites in PPy nanowires [101] While a strategy for the fabrication of conducting polymer nanowires on thermally oxidized Si surfaces by the use of DNA as ... Whenever, there is a contact of these doped nanowires with the analyte, there are changes inthe electrical characteristics The use of nanomaterials of CP could greatly improve diffusion since they...
... ion-binding site is not conserved in hairpin If one assumes the same number of hairpins in V0 and F0, the rotor of V1V0ATPases has only half the number of ion-binding sites This is seen as the ... specific ATPase activity ofthe complete enzyme was inthe range 5–9.9 UÆmg)1 protein, depending on the batch This is inthe same range as the one determined previously with the incomplete enzyme [25] ... potential (DpNa), there was no ATP synthesis (Fig 5) Upon addition of lm valinomycin, a membrane potential (DY, inside positive) was created in addition by thein ux of K+ into the liposomes (potassium...
... stress-free single crystal ofthe volume V, the strain energy release ofthe system occurs The strain energy release can change depending on the orientation ofthe stress-free crystal The strain ener ... [53] The Taylor factors and the measured stored energies indicate that the driving force for Rex is higher inthe Cu oriented grains than inthe S oriented grains Therefore, the Cu component inthe ... Correspondence between the directions in as-deposited grains and the directions in Rexed grains is therefore im possible in a grain Two ofthe directions in neighboring grains, which are...
... DU TRONG TIẾN TRÌNH VĂN HỌC TRUNG ĐẠI” (NGUYỄN TRÃI AND NGUYỄN DU INTHEEVOLUTIONOFTHE MEDIEVAL LITERATURE) _ Thông tin giảng viên: Họ tên: Trần Nho Thìn Chức danh: PGS TS Giảng viên ... sách nghiên cứu NT nghiên ND cứu NT ND theo định Tuần Thời Hình gian, Nội dung Mục tiêu cần Sinh viên thức địa điểm đạt chuẩn bị Đọc Hướng Thư dẫn sinh Sinh viên tự học SV nắm học liệu viện, nhà ... dung Mục tiêu cần Sinh viên thức địa điểm Đưa chọn từ đạt Sinh viên biết tư chuẩn bị Chuẩn bị Thảo giờ, đề xuất sinh độc lập, biết tập cá luận lớp viên vấn đề, đề tìm vấn đề nhân Sinh viên rèn khả...
... Over the past couple of years advances have been made inthe understanding ofthe involvement of T cells inthe immunopathology of autoimmune diseases, with a focus on proinflammatory cytokine ... that the proapoptotic protein Bid, an intermediary for the extrinsic and intrinsic apoptotic pathways, is important inthe development of inflammatory arthritis Mice lacking Bid display increased ... O isoforms, which are targets ofthe PI3 kinase/PKB signalling pathways and play emerging roles inthe regulation of inflammatory responses The Forkhead box class O isoforms are expressed in RA...
... and C elegans (total of 98,695 introns) for TE insertions to determine the percentage of TE-containing introns (Figure 2a) The fraction ofthe introns that contain TEs inthe non-mammalian vertebrates ... (Const.) The table on the right shows the numbers of exonized TEs in each ofthe examined species (b) Summary ofthe effect of TE insertions into the first or last exons (i) Illustration of insertion ... respectively The grey boxes show insertion of TEs into exons The TE family is indicated beneath the gray box, along with the length of each inserted TE Lengths ofthe introns and exons flanking the inserted...
... appeared at the root ofthe bilaterian tree, and domains involved in lipid catabolic process appeared during theevolutionofthe first chordates On the other hand, domain losses during animal evolution ... to the functions of lost and gained domains enabled us to obtain a more detailed view ofthe interplay between domain losses and gains (Tables and 4) Within an overall increase in domains involved ... section) The first finding is that the functional profiles of sets of domains lost and gained at most branching points differ drastically: on the path leading from the LECA to mammals, domains with...
... identified This finding demonstrates the complexity of these regulatory path ways and the inherent difficulties of precisely defining them inthe laboratory FOXP2 inthe brain The expression of FOXP2 ... brainstem responses [32] in heterozygous pups In song-birds, it has been reported that reducing the expression of FoxP2 in an area ofthe brain necessary for vocal learning can interfere with the ... ‘humanizing’ them at the locus), this resulted in an altered structure of innate pup vocalizations, decreased levels of exploration, decreased levels of dopamine inthe brain and an increased...
... study the mechanism of antiHIV-1 integrase Evidence suggests that curcumin does not bind to HIV-1 integrase at either the DNA-binding domain [58] or the binding site of another HIV-1 integrase inhibitor, ... HIV-1 integrase is the enzyme that catalyzes the integration ofthe doublestrained DNA of HIV into the host chromosome [54] Curcumin inhibited this activity of HIV-1 integrase [54] Other classes of ... phytohematoglutinin, concanavalin A, and pokeweed mitogen were examined inthe presence of AZT, curcumin, and turmerin In infective assays, neither turmerin nor curcumin of a phenolic OH group for the anti-oxidant...
... focused on the ontogenetic and phylogenetic origin ofthe tissue from the dorsal area ofthe ancestral chordate neural tube Along these lines, the rewiring ofthe genes involved inthe neural ... emergence inthe neural crest relates to the rate of innovation in other tissues, we plotted the cumulative number of genes appearing in each category In these graphs, the tissue-specific evolutionary ... crest evolutionin particular Individual analysis ofthe function of these peptides during the development ofthe neural crest demonstrates that they control the commitment of precursors to the...
... (PB2, PB1, PA) ofthe 1918 A/ H1N1 virus were of avian origin, since they are outside ofthe spectrum ofthe A/H1N1 folding energies and inthe lower spectrum of folding energies of all human viruses ... at the nucleotide level, only one of them was used inthe analysis As we explained above, the choice of focusing on the ORF was dictated by the fact that the majority ofthe sequences inthe ... correlation with the measured MLD50 values (R = -0.97) The effect ofthe folding energy on theevolutionofthe virus appears to be independent ofthe concurrent amino acid changes inthe polymerase...
... contribution from the shock to the retail interest rate at the end ofthe period (of around 37 basis points in February 2011), which probably reflects therecent increase inthe financing costs of Belgian ... job of showing the relevance of Euribor during the crisis period for savings deposit rates and the instability ofthe model estimated using the OIS, as was the case for the euro area However, the ... the start ofthe crisis Conversely, inthe case ofthe model estimated using the OIS, both the increase and decrease inthe retail interest rate are principally due to the shock to the retail...
... threats in training, not only in air but also in space and cyber operations • extending integrated air warfare training to the surface and subsurface Navy • enlisting the real-time involvement of ... commander ofthe Navy’s Second Fleet, such integration “is now a part ofthe culture” of U.S combat aircrews, regardless of whether the wings they wear on their uniforms are made of silver or gold.3 In ... blending Marine F/A-18A and C squadrons into Navy carrier air wings as a matter of standard practice.6 Finally, inthe realm of doctrine, there was an emergent Navy acceptance ofthe value of strategic...
... encoding the two motifs ofthe C-terminal domain The crygn gene is thus a hybrid of b and c crystallin gene structures, apparently an intermediate intheevolutionofthe c-crystallins from the ... part of a suite of molecular adaptations inthe eye inthe human lineage In addition to theevolutionof cN and cS crystallins, even more specialization inthe c-crystallins has occurred with the ... encodes the first two structural motifs, and hence the N-terminal domain ofthe protein, just as inthe genes for cS and cA–F However, the second half ofthe gene has the structure of a b-crystallin...
... is inthe West," were associated inthe minds ofthe Egyptians as the protecting deities of Abydos The worship of these gods as the chief Southern deities ofthe dead, and the preeminence ofthe ... like those ofthe old Memphite kings These facts, ofthe situation of Itht-taui, of their burial inthe southern an ex ofthe old necropolis of Memphis, and ofthe fori of their tombs (the true ... Tablets," and the "Great Tell," and, rising as they inthe centre ofthe site, they mark the position ofthe temples and the other principal buildings ofthe city CHAPTER IV 51 An indication ofthe richness...
... Second, we examine theevolutionof host choice Recently a phylogeny was constructed ofthe genus Phyllonorycter that includes all the (British) hosts ofthe Achrysocharoides included in our phylogeny ... Rosales (a), Sapindales (b) and Fabaceae (c) include these in a future study to investigate the number of colonisations of herbs by these wasps Interestingly, the only upper surface leaf miner parasitoid ... ancestral host of Achryso- chroides Regarding the effect of taxa sampling on the reconstruction of reproductive strategies, although the biology of most species in other parts ofthe world is less...
... objectivity Recent Large Service Acquisitions inthe Department of Defense Lessons for the Office ofthe Secretary of Defense FRANK CAMM IRV BLICKSTEIN JOSE VENZOR Supported by the Office ofthe Secretary ... time to determine how well they work in practice The case studies offer the best insight into the execution ofthe two oldest acquisitions, the Army BSC and R2CSR programs For the other four acquisitions, ... (FFRDC) sponsored by the iii iv Recent Large Service Acquisitions inthe Department of Defense Office ofthe Secretary of Defense, the Joint Staff, the Unified Commands, and the defense agencies...
... because ofthe alternative costs of verifying “each sack of purchased flour” and of employing “persons in devising methods of detecting the new modes of adulteration which might be continually ... on the investment of acquiring new customers There might also be benefits from the change inthe long-term behaviour (e.g increased loyalty) of existing customers The problem of asymmetric information ... be shrinking over time (due to the increasing cost of time and memory inthe mt The household production function) Thus there is a tendency that nt rest ofthe quality characteristics ofthe product...