rb tp53 tumour suppressor network
Báo cáo khoa học: Proteolysis of the tumour suppressor hDlg in response to osmotic stress is mediated by caspases and independent of phosphorylation pot
... DAPI Sorbitol hDlg hDlg + DAPI Sorbitol hDlg + DAPI Cytop Memb hDlg Cytop Memb Cytop Memb hDlg + DAPI Cytop Memb B hDlg InsR Calpain Sorbitol Control Cell density C No inhibitor 50% 100% BIRB0796 ... Control Cell density C No inhibitor 50% 100% BIRB0796 a Sorbitol Control BIRB0796 + zVAD zVAD d g j b e h k c f i l Treatment None h Sorbitol h Sorbitol + h release hDlg 394 hDlg hDlg hDlg FEBS Journal ... of hDlg Cell density A 50% – Sorbitol + – + hDlg (S158) hDlg (total) Cell density B 50% Sorbitol – Time (h) 100% + – 14 + 14 hDlg (total) GAPDH C Time after sorbitol treatment (h) D Time after...
Ngày tải lên: 23/03/2014, 06:20
Báo cáo khoa học: A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP docx
... Biel MA, el Deiry W, Nelkin BD, Issa JP, Cavenee WK, Kuerbitz SJ & Baylin SB (1995) p53 activates expression of HIC-1, a new candidate tumour suppressor gene on 17p13.3 Nat Med 1, 570–577 Chen WY, ... the role played by the HIC1–CtBP interaction in two mutually nonexclusive pathways: the HIC1 tumour suppressor properties, which are altered in many human cancers, and normal development CtBP ... recruitment of class I or class II HDACs Discussion In this report, we demonstrate that the tumour suppressor gene and transcriptional repressor HIC1 interacts with the related but not fully...
Ngày tải lên: 23/03/2014, 10:21
Designing a synthetic tumour suppressor protein
... Soft agar assay as an anchorage independence test for tumourigenicity 188 6.3.2 Foci formation assay as a contact inhibition test for tumourigenicity 190 6.4 Generation of the aptamers with ... important for tumour growth and metastasis In summary, upregulation of eIF4E leads to enhanced translation of mRNA transcripts that encode proteins that promote proliferation, tumourigenesis ... eIF4E mediates its tumourigenic activity 134 Nonetheless, this project aims to specifically disrupt the translation initiation function of eIF4E, which has been implicated in tumourigenesis Diagram...
Ngày tải lên: 14/09/2015, 14:08
Tổng quan về NAT (Network Address Translation)
... tham số hệ điều hành máy tính gán cách tự động thông qua giao thức DHCP Địa địa IP hợp lệ cấp NIC (Network Information Center) nhà cung cấp dịch vụ Internet Inside global address - Là địa hợp lệ ... dụng virtual server thay cho nhiều host thật (real server) Chúng ta tạo kết nối mạng ảo (virtual network) gồm nhiều mạch thật (real wire) dùng kỹ thuật virtual server Chúng ta làm điều với NAT ... NAT Có số trường hợp việc NAT truy tìm IP hoàn toàn không hiệu Đó ứng dụng virtual server virtual network traffic sinh IP phân chia Khi yêu cầu NAT truy tìm thêm TCP/UDP port cân tải giảm traffic...
Ngày tải lên: 15/08/2012, 10:40
Advanced Java Networking
... be it Java Fundamentals; Core Networking such as RMI, CORBA, or Java Database Connectivity (JDBC); Advanced Networking like Beans and Web Servers; general Java Networking information, including ... the connection, telling the Network module that it wants to exit Network Modules The Network module will be changed from chapter to chapter to reflect the new form of network communication However, ... stack to the network (IP) layer In the network layer each packet is further encapsulated by appending a header containing network routing information to the beginning of the packet The network layer...
Ngày tải lên: 23/08/2012, 16:17
INTER-SYMBOL INTERFERENCE CANCELLATION FOR GSM SYSTEM USING NEURAL NETWORKS EQUALIZER
Ngày tải lên: 03/09/2012, 15:54
Tổng quan Neural networks
... nghiệm Đặc trưng khác phân biệt RBF MLP khác không gian mô phỏng, RBF kết thành khối MLP dàn trải Những người có kinh nghiệm làm việc với RBF nói mặt phẳng đáp ứng RBF lệch tâm cần nhiều neuron ... Neural Networks • Dữ liệu số danh đònh xử lý trực tiếp Neural Networks Chuyển loại biến khác sang dạng • Cần hàng trăm hàng ngàn trường hợp mẫu huấn luyện; nhiều biến nhiều mẫu huấn luyện Neural Networks ... Gaussian) RBF có lớp ngõ chứa neuron tuyến tính có hàm kích hoạt tuyến tính Lê Thanh Nhật-Trương Ánh Thu 100 GVHD : Ths Hoàng Đình Chiến Phần 3_Chương : Tổng quan Neural Networks Mạng RBF có số...
Ngày tải lên: 03/09/2012, 15:54
Tài lieeuk tham khảo Ứng dụng bộ cân bằng dùng NEURAL NETWORKS triệt nhiễu giao thoa kí tự trong hệ thống GSM
... PC-DSP, ISBN 0-13-079542-9 [18] Bart Kosko, Neural Networks for Signal processing, ISBN 0-13-614694-5 [19] Tarun Khanna, Foundations of Neural Networks, ISBN 0-201-50036-1 [20] Matlab_The language ... Ứng dụng cân dùng Neural Networks triệt nhiễu giao thoa ký tựï hệ thống GSM [16] Edwin Johnes, Digital Transmision, ISBN...
Ngày tải lên: 03/09/2012, 15:55
Ứng dụng bộ cân bằng dùng NEURAL NETWORKS triệt nhiễu giao thoa kí tự trong hệ thống GSM
Ngày tải lên: 03/09/2012, 15:59
Network Managerment
... Chapter 9: Network Management Chapter goals: Ì introduction to network management r motivation r major components Ì Internet network management framework r MIB: management ... definition language r SNMP: protocol for network management r security and administration Ì presentation services: ASN.1 Network Management 9-2 Chapter outline Ì What is network management? Ì Internet-standard ... Transport Mappings r Security and Administration Ì ASN.1 Network Management 9-3 What is network management? Ì autonomous systems (aka network ): 100s or 1000s of interacting hardware/software...
Ngày tải lên: 12/09/2012, 15:05
Introduction Computer networking
... look at network structure: network edge: applications and hosts network core: routers network of networks access networks, physical media: communication links Introduction 1-11 The network ... 1.1 What is the Internet? 1.2 Network edge 1.3 Network core 1.4 Network access and physical media 1.5 Internet structure and ISPs 1.6 Delay & loss in packet-switched networks 1.7 Protocol layers, ... 1.1 What is the Internet? 1.2 Network edge 1.3 Network core 1.4 Network access and physical media 1.5 Internet structure and ISPs 1.6 Delay & loss in packet-switched networks 1.7 Protocol layers,...
Ngày tải lên: 12/09/2012, 15:05
Network Layer
... link physical network data link physical network data link physical network data link physical network data link physical network data link physical network data link physical network data link ... multicast routing Network Layer 4-10 Network layer connection and connection-less service Ì datagram network provides network- layer connectionless service Ì VC network provides network- layer connection ... Network Layer 4-46 NAT: Network Address Translation rest of Internet local network (e.g., home network) 10.0.0/24 10.0.0.4 10.0.0.1 10.0.0.2 138.76.29.7 10.0.0.3 All datagrams leaving local network...
Ngày tải lên: 12/09/2012, 15:06
Multimedia Networking
... Multimedia applications: network audio and video (“continuous media”) QoS network provides application with level of performance needed for application to function 7: Multimedia Networking 7-2 Chapter ... Differentiated Services Ì 7.9 RSVP Ì 7.5 Distributing Multimedia: content distribution networks 7: Multimedia Networking 7-4 MM Networking Applications Classes of MM applications: 1) Streaming stored audio ... compensate for network- added delay, delay jitter 7: Multimedia Networking 7-21 Streaming Multimedia: UDP or TCP? UDP Ì server sends at rate appropriate for client (oblivious to network congestion...
Ngày tải lên: 12/09/2012, 15:06
Network Security
... practice: r firewalls r security in application, transport, network, link layers 8: Network Security 8-2 Chapter roadmap 8.1 What is network security? 8.2 Principles of cryptography 8.3 Authentication ... Chapter 8: Network Security Chapter goals: Ì understand principles of network security: cryptography and its many uses beyond “confidentiality” ... control: firewalls 8.7 Attacks and counter measures 8.8 Security in many layers 8: Network Security 8-3 What is network security? Confidentiality: only sender, intended receiver should “understand”...
Ngày tải lên: 12/09/2012, 15:06
Neural Networks (and more!)
... close to the main topic of this chapter, the neural network Neural Network Architecture Humans and other animals process information with neural networks These are formed from trillions of neurons ... Chapter 26- Neural Networks (and more!) 461 x1 x2 FIGURE 26-6 Neural network active node This is a flow diagram of the active nodes used in the hidden and output layers of the neural network Each input ... common to hear neural network advocates make statements such as: "neural networks are well understood." To explore this claim, we will first show that it is possible to pick neural network weights...
Ngày tải lên: 13/09/2012, 09:50
John Wiley And Sons Wireless Networks eBook LiB
... Chapter 7.2 Satellite Systems 7.2.1 Low Earth Orbit (LEO) 7.2.2 Medium Earth Orbit (MEO) 7.2.3 Geosynchronous Earth Orbit (GEO) 7.2.4 Elliptical Orbits 7.3 VSAT Systems 7.4 Examples of Satellite-based ... WLAN is a peer-to-peer network that is set up in order to serve a temporary need No networking infrastructure needs to be present and network control is distributed along the network nodes An infrastructure ... Satellite orbits belong to three different categories In ascending order of height, these are the circular Low Earth Orbit (LEO), Medium Earth Orbit (MEO) and Geosynchronous Earth Orbit (GEO)...
Ngày tải lên: 13/09/2012, 10:21