... technologies in conformal radiation therapy, dynamic intensity modulation and three-dimensional endovascular brachytherapy They also describe new tools of threedimensional brachytherapy and analyze clinical ... current understanding only of the effects of epidermal growth factor (EGF) and its receptor (EGFR) in cell and tumor response to radiationand their implications for tumor radiotherapy EGFR Signal ... emission tomography (PET) and di- Fig Stereotactic fixation (mask system made from Scotch cast bandages) and positioning equipment used in precision radiotherapy of head and neck and brain lesions gital...
... Leibel SA, Fishman EK: 194 hepatocellular cancers treated by radiationandchemotherapy combinations: toxicity and response: a RadiationTherapy Oncology Group Study Int J Radiat Oncol Biol Phys ... AT: Dosimetric analysis and comparison of three-dimensional conformal radiotherapy and intensity-modulated radiationtherapy for patients with hepatocellular carcinoma and radiation- induced liver ... MJC and KHC took care of patients HCT, NSC and HJT made the treatment planning and carried out all plans comparisons and evaluations DYCH and YJ C participated in manuscript preparation and study...
... smoking history Chemotherapy was done before radiation in 21 patients (62%), and concurrent chemoradiotherapy was done in 15 patients (44%) The used regimens for concurrent chemotherapy were combinations ... 63:324-333 Marino P, Preatoni A, Cantoni A: Randomized trials of radiotherapy alone versus combined chemotherapyand radiotherapy in stages IIIa and IIIb non-small cell lung cancer a meta-analysis ... A: Radiotherapy alone versus combined chemotherapyand radiotherapy in unresectable non-small cell lung carcinoma Lung Cancer 1994, 10(Suppl 1):S239-S244 Mehta V: Radiation pneumonitis and pulmonary...
... Brachytherapy and Transient PSA Elevations Following HDR Brachytherapy and External Beam Radiation Pt = Patient Init PSA = Initial PSA Patients 1, 3, and were received hormone therapy for 7, and ... beam radiationtherapy (EBRT) and/ or brachytherapy are mainstays of local therapy Low dose rate (LDR) brachytherapy, with permanently implanted radioactive seeds, [2-6] and HDR brachytherapy, with ... greater than months of adjuvant hormone therapy were excluded Five patients received no hormone therapyand patients received neo-adjuvant and concurrent hormonal therapy, which was discontinued after...
... Tissue Avoidance Table and Figure summarize the mean D5 and V40 values for the bladder, SB, and rectum IMRT planning produced significantly lower D5 and V40 values for the bladder and the SB (p < 0.05) ... conformal radiotherapy (blue line) f3DCRT: modificated tridimensional conformal radiotherapy (pink line) IMRT: intensity modulated radiationtherapy (green line) Table Homogeneity and Conformity ... f3DCRT (B and E) and IMRT (C and F) The orange line represents the 95% isodose c3DCRT: conventional tridimensional conformal radiotherapy f3DCRT: modificated tridimensional conformal radiotherapy...
... changes for head -and- neck patients, including nodal mass shrinkage and patient weight loss during the course of radiation therapy, can occur [28,29] For these cases, repeat CT imaging and re-planning ... KV-cone beam CT Radiotherapy and oncology 2006, 81(Supplement 1):26 27 Brock KK: Image registration in intensity-modulated, image-guided and stereotactic body radiationtherapy Front Radiat Ther ... of kilovoltage X-ray volume imaging in patient dose calculation for head -and- neck and partial brain radiationtherapyRadiation Oncology 2010, 5:29 Page 10 of 10 ...
... investigation of intensitymodulated radiationtherapy versus conventional two-dimensional and 3D-conformal radiationtherapy for early stage larynx cancer Radiation Oncology 2010 5:74 Submit ... Intensity-modulated radiationtherapy for prostate cancer: late morbidity and results on biochemical control Radiother Oncol 2007, 82:160-166 Kim K, Wu HG, Kim HJ, et al: Intensity-modulated radiationtherapy ... dose radiation to the carotid arteries can lead to vascular disease Several reports have shown that head and neck radiation using conventional techniques can cause carotid artery stenosis and...
... intensitymodulated radiationtherapy (IMRT) andchemotherapy Radiother Oncol 2009, 93:298-301 10 Pepek JMWCG, Clough RW, Wu QJ, Yoo S, Czito BG: Intensity Modulated RadiationTherapy (IMRT) for ... M, Pierart M: Concomitant radiotherapy andchemotherapy is superior to radiotherapy alone in the treatment of locally advanced anal cancer: results of a phase III randomized trial of the European ... intensitymodulated radiationtherapy (IMRT) Int J Radiat Oncol Biol Phys 2003, 57:543-552 Randall ME, Ibbott GS: Intensity-modulated radiationtherapy for gynecologic cancers: pitfalls, hazards, and cautions...
... complete surgical remission after induction chemotherapy: a randomized, controlled, clinical trial comparing whole abdominal radiotherapy, chemotherapy, and no further treatment Int J Gynecol Cancer ... Southern Switzerland, Bellinzona, Switzerland Authors’ contributions UM carried out the study conception and design and drafted the manuscript LC carried out the study conception and design and drafted ... Delclos L: Postoperative treatment of early cancer of the ovary: a random trial between postoperative irradiation andchemotherapy Natl Cancer Inst Monogr 1975, 42:49-53 Einhorn N, Lundell M,...
... lymph nodes and primary tumor sites must be irradiated List of abbreviation ASTRO: Americal Society of Therapeutic Radiation Oncology; CRT: Conformal Radiation Therapy; CT: Chemotherapy; CTV: ... Organization on RadiationTherapy Consortium; GI: Gastrointestinal; GU: Genitourinary; ICRU: International Comission on Radiation Unit and Mensurements; IMRT: Intensity Modulated Radiation Therapy; ... GI and GU toxicities during the RT Symptoms and treatment were recorded on the chart We retrospectively reviewed these charts and graded acute GI and GU toxicities by the RTOG/EORTC acute radiation...
... first and liver metastasis subsequently Two Table The distribution of recurrences and survivals in radiotherapy and no-radiotherapy group Radiotherapy Group Radiotherapy n = 66 NoRadiotherapy ... extension, lymphatic, vascular and perineural invasion, and ratio of involved nodes/ dissected nodes), and treatment-related factors (PMRT, chemotherapyand hormonal therapy) were analyzed (Table ... For the entire group, LRR and DM rates were 7% and 20%, respectively, and years actuarial DFS and OS rates were 73.6% and 81.9%, respectively Differences between RT and no-RT groups were statistically...
... and regularly in patients undergoing chemotherapy for other sites of disease The lesions were contoured using dedicated medical image analysis software (MIMvista®, MIM Software, Inc., Cleveland, ... inclusion criteria and were analyzed Overall, 17 Fractionation schedules and conversion to single fraction equivalent dose (SFED) and biological equivalent dose (BED) Stinauer et al Radiation Oncology ... melanoma and RCC lesions Page of We generated TCP graphs using both SFED and BED (Figure 2) Both SFED and BED had a strong coefficient of determination to predict future outcomes (SFED R = 0.999 and...
... (surgery and radiotherapy, surgery only, radiotherapy only, and neither surgery nor radiotherapy) (p < 0.01) The percentage of cases surviving five years by treatment modality was: 73% for surgery and ... The Role of Chemotherapy The SEER database did not include information for those treated with chemotherapy, however recent reports of outcomes for ONB patients have included chemotherapy [11-15] ... best outcomes follow surgery combined with radiotherapy The efficacy, timing, and optimum method of integrating chemotherapy with surgery and radiotherapy remain unknown Acknowledgements This work...
... administration with chemotherapy [2,3] Moreover, Sauer and colleagues, demonstrated that preoperative chemoradiation was superior with respect to the rates of local recurrence and sphincter preservation ... reviewed and deemed clinically acceptable by both a gastrointestinal clinical physicist andradiation oncologist Plan evaluation and statistical tools Evaluated volumes included the PTV and relevant ... out the study conception and design and drafted the manuscript MBP performed treatment planning TMB and SB performed physics checks/plan evaluation Patient accrual andradiation field design were...
... concurrent reirradiation andchemotherapy arm of this trial used the same regimen as in RTOG Yamazaki et al Radiation Oncology 2011, 6:98 http://www.ro-journal.com/content/6/1/98 99-11; the chemotherapy- alone ... salvage surgical resection and 36 (49%) received chemotherapy The median reirradiation dose was 60 Gy and the median lifetime radiation dose was 116.1 Gy Severe irradiation-related toxicity occurred ... Machtay M, Li Y: Locally recurrent, previously irradiated head and neck cancer: concurrent reirradiation and chemotherapy, or chemotherapy alone? J Clin Oncol 2006, 24:2653-8 10 Langer CJ, Harris...
... in patients receiving adjuvant chemotherapy compared to patients not receiving adjuvant chemotherapy (data not shown) Association between TATI in tissue and serum and clinicopathological characteristics ... tumour tissue and normal mucosa before and after radiotherapy Box plots showing TATI expression levels in tumour tissue before and after RT (A), and in normal mucosal tissue before and after RT ... 12 days into RT (at half-time) and after completion of treatment No patients received neoadjuvant chemotherapy Thirteen patients (24.5%) received adjuvant chemotherapy after surgery Serum samples...
... withdrawn and the primary tumor alone is treated to 79,2 Gy V20 right and left lung and V25 both lungs is 49%, 22% and 26%, respectively V50 for the heart is 2% Peripheral tumor located lateral and ... Sedlmayer F: NSCLC: Primary tumor size -Radiation dose-related accelerated, twice daily radiotherapy by target splitting, preceded by two cycles of chemotherapy – first results of a prospective ... Sohn J, Suh J, Pohar S: A method for delivering accurate and uniform radiation dosages to the head and neck with asymmetric collimators and a single isocenter Int J Radiat Oncol Biol Phys 1995,...
... MR: Trimodality therapy with inductin chemotherapy followed by extrapleural pnemonectomy and adjuvant high-dose extrapleural pneumonectomy and adjuvant high-dose hemithoracic radiation for malignant ... 47 MPM patients with a dose of 40 Gy in 20 fractions with and without chemotherapyand they informed that all of patients experienced radiation induced pulmonary fibrosis [29] However, in this ... stage II and III MPM, and the authors reported accuracy of 77% for CT, 86% for PET, 80% for Magnetic Resonance Imaging (MRI), and 100% for PET-CT in patients with stage II disease, and accuracy...
... type, and extent of disease, initial Karnofsky score, dose and fractionation radiotherapy schedule, surgery, chemotherapyand RPA class, showed in table The supportive care (oral prednisone) and ... prednisone) and neurological status was not evaluated Chemotherapy was Results The overall survival rate in 1, and years was 24%, 9.4%, and 4.3%, respectively (figure 1) Three patients were alive ... metastasis and higher KPS The RadiationTherapy Oncology Group (RTOG) has attempted to determine the optimal dose fractionation schedules for patients with brain metastasis in various randomized...