quality an important factor in the well
Tài liệu Báo cáo Y học: The b-1,4-endogalactanase A gene from Aspergillus niger is specifically induced on arabinose and galacturonic acid and plays an important role in the degradation of pectic hairy regions pdf
... and containing the galA gene and approximately 700 bp 3¢-flanking region, in pIM4700 (containing the pkiA promoter) A niger The sugar composition of the arabinogalactans from potato, onion and soy ... proteins in A niger [33] The fusion construct (pIM3982) was made by introducing an NsiI site at the translation start point of galA and by then cloning a fragment, starting at this NsiI site and ... detected in the preparation (data not shown) This paper demonstrates the important role of GALA in the degradation of both linear and L-arabinose-substituted galactan side chains of pectin This is in...
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Báo cáo y học: "Defective CD4+CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-γ" potx
... the following scoring system for each limb: score 0, normal; score 1, redness and/or swelling in one joint; score 2, redness and/or swelling in more than one joint; score 3, redness and/or swelling ... days 27 and 40 after immunisation is shown in (d) The mean limb score of the arthritic mice in the two groups is also indicated for the two time points and is significantly higher in the treated ... in the co-cultures or in vivo in mice We therefore analysed the expression of TGF-β by quantitative PCR in Treg cells as well as in co-cultures and in spleens of naive and immunised mice The...
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Báo cáo y học: "Pro/con debate: Octreotide has an important role in the treatment of gastrointestinal bleeding of unknown origin" pptx
... flowmetry in rabbits and man Am J Gastroenterol 1999, 94:1077-1082 19 Collins R, Langman M: Treatment with histamine H2 antagonists in acute upper gastrointestinal hemorrhage Implications of randomized ... omeprazole and a combination of somatostatin and ranitidine in severe GI bleeding [27] It is thus unlikely that somatostatin or octreotide can improve on results of high dose PPIs in patients ... high and low risk of rebleeding [11] Pro’s response: Defining the indication Yaseen Arabi and Bandar Al Knawy Octreotide use as an adjunct to endoscopic therapy [21,24,32] should be distinguished...
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Tài liệu Báo cáo khoa học: The molecular surface of proteolytic enzymes has an important role in stability of the enzymatic activity in extraordinary environments pptx
... the N-terminal region on the molecular surface In the wildtype enzyme, the side chain of Asp266 interacted with the amino group of the main chain at Glu268 The oxygen of the main chain at Asp266 ... temperature indicates the stability of the structure of the protein The difference of the increments between the inactive temperature and the Tm should indicate that the mutations improved the stability ... enclosed in dark boxes and in open boxes are common sequences among ALP I and the neutral subtilisins, and among ALP I and the alkaline subtilisins, respectively s, Unique amino acid sequence in the...
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Báo cáo khoa học: Piecing together the structure of retroviral integrase, an important target in AIDS therapy pptx
... remove the overhanging viral 5¢-dinucleotides and seal the gaps on both sides of the integrated viral DNA In the final product, the viral insert is flanked by the repeated stagger sequence, and begins ... the protein, it provided the first chain tracing, and was important in revealing the plasticity of the IN active site and its ability to adopt different conformations Perhaps the most significant ... from the cellular IN- binding protein LEDGF, to inhibit the DNA-binding of IN by shifting the enzyme’s oligomerization equilibrium from the active dimer towards the tetramer, which, according to their...
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báo cáo khoa học: " Transcriptional profiling of Medicago truncatula under salt stress identified a novel CBF transcription factor MtCBF4 that plays an important role in abiotic stress responses" ppt
... reduce ROS threat and maintain osmotic balance, such as the anthocyanin and isoflavone pathways were induced, indicating an active response and defense mechanism protects the plant against external ... underlined) An NcoI-SpeI fragment containing MtCBF4 cDNA was inserted into pCAMBIA1302 containing the 35S CaMV promoter and a hygromycin (kanamycin) resistance marker The plasmid was introduced into ... anthocyanin biosynthesis improves a plant’s ability to guard against oxidative damage and protects it from such injury Anthocyanin reportedly functions in the cell membrane as an antioxidant to...
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Báo cáo y học: "B cells from rheumatoid arthritis patients show important alterations in the expression of CD86 and FcgRIIb, which are modulated by anti-tumor necrosis factor therapy" potx
... participated in the conception and design of the study and critically revised the manuscript JCA participated in the conception and design of the study and in the interpretation of data and helped ... participated in the recruitment and clinical evaluations of patients LS participated in the recruitment of patients and clinical data analysis MC participated in the design and coordination of the study ... important alterations in the phenotype of peripheral B cells from RA patients, involving the expression of the co-stimulatory molecule CD86 and the inhibitory receptor FcgRIIb, the latter being...
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Characterization of plasma myosin heavy chain in zebrafish as an important factor for ompa mediated anti phagocytic function
... diagnosis, the change of the concentration of MHC in human serum and plasma is an important factor to examine the muscle injury and myosin-related diseases 12 1.3 The role of Outer membrane protein A ... belongs to innate immune system and is the first defense line in our human body (Ogra, 1998) Skin is the most important barrier to the invaders as most of the organisms cannot penetrate the skin unless ... chain can regulate the function of myosin by changing the conformation of myosin heads to detach from actin, increasing population placed close to thin filaments, potentiating actin-myosin interaction...
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Hydrophytes may play an important role in sewage disinfection in constructed wetlands
... Hydrophyte is an indispensable component in CWs Researches show that the plants can produce allelochemicals and affect on the growth of other living beings The allelochemicals of the hydrophytes inhibited ... altissma and Brucea javanica, and indicated that their extracts not only inhibited the infection of TMV, but also had the inhibition for the replication of TMV Tan Q W (2007) indicated 2-dihydroailanthone ... respectively In conclusion, P hydropiper may play an important role in sewage disinfection in CWs, but its living inhibiting pathogenic micro-organisms in the ecosystem need to be further studied...
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Tài liệu Water quality management for irrigation in the mekong river delta, Vietnam doc
... the along the river and canal banks, resulting a high concentration of human pollutants along the water bodies in the Delta Fig.1: The Mekong River Basin and Land forms of the MD in Vietnam The ... local rainfall and runoff, the amplitude of tides in the East Sea and the Gulf of Thailand, the slope of the river bed, the wind velocity and direction and the depth of the estuary Salt water intrudes ... epidemics, increase in the early rain season and the end of flooding periods due to stagnant water in the sunken places WATER QUALITY MONITORING The water quality monitoring data and information...
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Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc
... isomerohydrolase in the retina Y Takahashi et al comprises the recycling of 11cRAL through a process involving multiple enzymes and retinoid-binding proteins between photoreceptors and retinal pigment epithelium ... cell type in the vertebrate retina, comprising a specialized radial cell that spans the entire thickness of the inner retina The Muller cell constitutes an ana¨ tomical link between the retinal neurones ... neurones and supports their activities by exchanging molecules between the other retinal layers [28] In addition, it has been shown that several retinoid-binding proteins and enzymes involved in vitamin...
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Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf
... of a brain-specific MT isoform, GIF, in 1991, sparked considerable interest in understanding the role of all MTs in the brain, and particularly within the injured or diseased brain In the case ... growth-inhibitory properties of GIF in AD There have been extensive studies examining the role of GIF in AD, linked to its initial discovery as a factor deficient in the AD brain There remains no ... and neurons, and may also promote excessive neurite sprouting Metal-binding properties of GIF and role in synaptic activity MTs are generally considered to have an important role in maintaining...
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Tài liệu “Don’t spit in the well - you may need to drink from it!” -- Unknown, Russia. docx
... lotions and soap, are being found in increasing concentrations in lakes and rivers Scientists have discovered that many PPCPs act as hormone disrupters, which means that the synthetic hormones in the ... suggest that these chemicals may be partially responsible for an increase in cancer and birth www.safewater.org defects For more information about PPCPs and other emerging contaminants, see the fact ... products interfere with the natural hormones in animals, especially fish that live in the water There has not been enough research to determine the effects that PPCPs can have on humans, but there...
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Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf
... covalently linked hairpins in the membrane [10] Importantly, the ion-binding site is not conserved in hairpin one If one assumes the same number of transmembrane helices in V0 and F0, the rotor of eukaryal ... handedness, and two of the rings face in the opposite direction in the membrane to the other two, forming the same pattern as in the AFM surface representation of Fig 2A By comparison with the ... Whereas the inner ring of densities is tightly packed, the outer one is more loosely arranged, and the densities correspond to the N- and C-terminal helices of the c ring, respectively The C-terminal...
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Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc
... to these interfaces is located in the PYR and middle domains The interface contains 10 hydrogen bonds in IPDC The dimer–dimer interface in IPDC is smaller than the corresponding interface in ... side chain Furthermore, there are significant structural differences between ZmPDC and IPDC on the one hand, and ScPDC on the other hand involving the C-terminal part of the polypeptide chain (Fig ... formed by the PYR domains from one subunit and the PP domains of the other subunit within the dimer ThDP adopts the V-conformation [30,31] and is completely buried in the cofactor binding cleft...
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Báo cáo khoa học: Transcriptional regulation of the desferrioxamine gene cluster of Streptomyces coelicolor is mediated by binding of DmdR1 to an iron box in the promoter of the desA gene doc
... by desA and its possible involvement in desferrioxamine biosynthesis, two apramycin-resistant and kanamycin-sensitive transformants were isolated among S coelicolor transformants with the desA ... procedures), and the DdesA mutation was verified in one of the mutants by PCR and Southern blot analysis A 1462-bp PCR band corresponding to the extended resistance cassette was found only in the mutant ... [12] Therefore, binding of the iron regulator DmdR1 will interfere with RNA polymerase interaction and expression of the desferrioxamine cluster Indeed, binding of the pure DmdR1 protein to the...
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Báo cáo khoa học: Secondary structure assignment of mouse SOCS3 by NMR defines the domain boundaries and identifies an unstructured insertion in the SH2 domain pdf
... according to TALOS, had amide resonances in the random coil region of the 15N-HSQC spectrum and showed significantly narrower line-widths than any other residues in the protein This indicates that the ... phosphotyrosine binding but may have an important functional role Results hydrophilic in PtdIns 3-kinase but not in SOCS3 were identified and mutated to match the PtdIns 3-kinase residue The six mutants ... acid, serine and threonine residues, and not contain lysine, arginine or histidine The X-ray structures of several proteins containing PEST sequences have been determined, but in each case the electron...
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Assessing the quality of investment advice in the retail banking sector docx
... made, the customer had an increased risk of getting back less than she had originally invested due to the short term and the impact of the initial charges Link to our work on inappropriate financial ... firms act in response to the RDR and ensure they deliver good advice Assessing the quality of investment advice in the retail banking sector Annex 19 Annex 1: Examples of recent retail banking sector ... www.fsa.gov.uk/pubs/final/barclays_jan11.pdf Assessing the quality of investment advice in the retail banking sector Annex 21 Annex 2: Using mystery shopping Our approach We want to use mystery shopping as...
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Báo cáo khoa học: Probing the interface between factor Xa and tissue factor in the quaternary complex tissue factor–factor VIIa–factor Xa–tissue factor pathway inhibitor pptx
... displayed in space filling and FVIIa in C-alpha ribbon The TF1 domain is in dark grey and the TF2 domain in light grey The Gla domain of FVIIa is shown in green; EGF1 in magenta; EGF2 in light ... Residues E99 and L104 are located in the TF1 domain, and T197 is situated in the N-terminal portion of the TF2 domain, i.e close to the TF1 domain at the level of EGF1 in FVIIa in the sTF–FVIIa ... spectra and in the rest of the mutants the probe was not significantly affected by the sTF–FVIIa complex formation As the purpose of our study was to map the interaction between FXa and sTF in the...
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Báo cáo khoa học: Deadenylation of interferon-b mRNA is mediated by both the AU-rich element in the 3¢-untranslated region and an instability sequence in the coding region pot
... (Fig 1A) We then analysed, by Northern blot, the induction and decay of IFN-b transcript in the same conditions As shown in Fig 1B, IFN-b mRNA was detectable h after the beginning of the infection, ... Discussion In the present study, we analysed the expression and the poly(A) status of human IFN-b mRNA in human endothelial Hec-1B cells in response to infection by the Sendaı¨ virus As observed in other ... cells were plated in six -well plates at 200 000 cells per well and were incubated for h before transfection After transfection, the cells were incubated for another 24 h and then infected by Sendaı¨...
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