... learning has also been applied, to the classification of proteins (Brown, 2000) and to cancerclassification (Golub, 1999) This last paper on leukemia classification presents a feasibility study ... Support Vector Machine Classificationand Validation of Cancer Tissue Samples Using Microarray Expression Data T Furey, N Cristianini, N Duffy, D Bednarski, M Schummer, and D Haussler To appear ... sizes and data differently distributed between training and test set (in the case of leukemia) One particularly challenging problem in the case of the colon cancer data is that “tumor” samples and...
... alkylphospholipid perifosine in CWR22RV1 prostatecancer both in vitro and in vivo In vitro, perifosine reduced cell viability and clonogenic survival, and enhanced apoptosis after radiation In ... perifosine and fractions of Gy radiation daily Variation between our results and previous results are likely caused by the differences in radiosensitivity between squamous cell carcinoma andprostatecancer ... perifosine in prostatecancer PC-3 cells Cells were irradiated in the absence (control) or in the presence of perifosine and the colony formation assay was conducted Shown are the means and standard...
... targeted therapeutics for prostatecancer candidate predictor of efficacy in both prostateand breast cancer Finally, the observed sensitivity to dasatinib of prostatecancer cell lines with expression ... established and validated classification of breast cancer subtypes that has been used in the clinic to aid patient stratification [25,26], molecular classification of prostatecancerusing genome-wide ... survival in prostatecancer [36,37] and its value as a prognostic marker has been well established in breast cancer [38,39] We found in our study that LNCaP cells, an androgen-sensitive prostate cancer...
... using the FRA module associated with the PGSTAT30 for frequencies between 100 kHz and 100 mHz and a perturbation amplitude of 10 mV Solutions were systematically deaerated with argon before and ... electropolymerised polypyrrole and carbon nanotubes, using ethidium bromide as redox indicator with high sensitivity, ca 85 pM Very few works were related to label-free and reagentless biosensors ... grade 2.2 CNTs preparation MWCNTs were purified and oxidized in a 1:1 mixture of HNO3 and H2SO4 at 90 1C for h, then washed with distilled water until pH and separated by centrifugation The solid residue...
... determination of the prostate position Daily correction of the position of the prostateusing fiducial markers minimizes the setup uncertainties [14] Several prospective and randomized trials have ... The prostate was delineated on a CT-scan and a margin of mm was applied to the prostateand seminal vesicles to create a planning target volume (PTV) Patients received an IMRT treatment using ... (IMRT) for prostatecancer Med Dosim 2005, 30:25-30 Heemsbergen WD, Peeters ST, Koper PC, Hoogeman MS, Lebesque JV: Acute and late gastrointestinal toxicity after radiotherapy in prostate cancer...
... familial risk of prostate cancer, and it is anticipated that many more prostatecancer susceptibility variants will be identified in the future Prostatecancer susceptibility variants and disease ... European descent and who underwent radical prostatectomy for treatment of prostatecancer [47] Based on the entire prostate gland, each tumor was uniformly graded and staged using the same protocol ... with prostatecancer mortality A prospective population-based cohort study of Swedish patients with prostatecancer explored the association between 16 established risk variants andprostate cancer...
... Murray T, Xu J, and Thun MJ Cancer statistics 2007 CA Cancer J Clin 2007; 57: 43-66 Li Y, and Cozzi PJ Targeting uPA/uPAR in prostatecancerCancer Treat Rev 2007;33(6):521-7 Catalona WJ and Smith ... step in the prostate tumorigenesis [59] C-myc is localized at chromosome [60] and its overrepresentation is associated with prostatecancer progression [61] Due to the fact that prostatecancer is ... permanent seed implants for localized prostatecancer BJU Int 2007; 99: 497-501 Sharifi N, Gulley JL, and Dahut WL Androgen deprivation therapy for prostatecancer JAMA 2005; 294: 238-244 Bloomfield...
... accuracy using the combined set of joining terms The less frequent joining terms achieve slightly better accuracy using the Nearest Neighbor and SVM algorithms, and very slightly worse accuracy using ... semantic relation Turney and Littman (2005) use a large and varied set of joining terms They include the most common prepositions, conjunctions and simple verbs like “has”, “goes” and “is” Also, they ... noun and modifier words as attributes, using a lexical hierarchy to extract these properties This approach was used by Rosario and Hearst (2001) within a specific domain – medical texts Using...
... Prostate cancer: diagnosis and treatment ii Chapter Title Prostate cancer: diagnosis and treatment February 2008 iii Prostate cancer: diagnosis and treatment Published ... Intelligence unit and Surveillance (WCISU) Between 1996 and 2004 the age standardised incidence rate of prostatecancer increased in all cancer networks in England and Wales1 In England the average ... Source: cancer registries of England and Wales Data Source: Office of National Statistics and Ordnance Survey Prostate cancer: diagnosis and treatment 1.4 Survival In most cases prostate cancer...
... guideline .38 Introduction Prostatecancer is one of the most common cancers in men Every year there are 34,986 new cases in England and Wales and 10,000 deaths Prostatecancer is predominantly ... die with prostatecancerand those who might die from prostatecancer Why this is important The greatest uncertainties in managing prostatecancer are around the identification of which cancers ... professionals and men with prostatecancer is essential It should be supported by evidence-based written information tailored to the man's needs Treatment and care, and the information men with prostate cancer...
... with prostatecancerand 27,050 men will die from prostatecancer in the U.S Q How is prostatecancer diagnosed? A Prostatecancer is most often diagnosed by needle biopsy of the prostate gland ... urinary bladder in men Q How common is prostate cancer? A Prostatecancer is the most common form of cancer in men (except for skin cancer) and a leading cause of cancer death worldwide In 2007, close ... General Information about ProstateCancer Q What is prostate cancer? A Prostatecancer is an abnormal (malignant) growth of the prostate, a walnut-sized gland at the base of the urinary...
... of Contents Nutrition, Exercise andProstateCancer Introduction Understanding the Links Between Nutrition, Exercise, andProstateCancer Effects of Oxidation and Inflammation The Contribution ... understanding of the roles of diet and exercise in the prevention of age-related diseases, as well as in the recurrence and progression of prostatecancer Nutrition, Exercise andProstateCancer ... Exercise andProstateCancer tissue that is removed surgically, and have found that inflammation leads to the atrophy, or wasting away, of normal prostate tissue adjacent to precancerous and cancerous...
... follow-up and therapeutic settings since the cancer has already been identified and characterized In anticipation of the identification of new markers in the future and the possibility of using cocktails, ... phenanthroline/Fe2+ complex, and then quantifying the concentration of a known dilution spectrophotometrically [14] Cell lines and flow cytometry MCF7, BT-474, and MDA-MB-231 breast cancer cells and Chinese hamster ... detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffinembedded cell lines and breast cancer tissue Diagn...
... expression in the androgen responsive prostatecancer cell line LNCaP It is an oncogene overexpressed in prostate, breast and ovarian cancer, as demonstrated by DNA microarray analysis and high density ... et al (2004) PrLZ, a novel prostate- specific and androgen-responsive gene of the TPD52 family, amplified in chromosome 8q21.1 and overexpressed in human prostatecancerCancer Res 64, 1589–1594 Byrne ... (2004) Overexpression, amplification, and androgen regulation of TPD52 in prostatecancerCancer Res 64, 3814–3822 Wang R, Xu J, Saramaki O, Visakorpi T, Sutherland WM, Zhou J, Sen B, Lim SD, Mabjeesh...
... behaviour, STDs and risks for prostatecancer Br J Cancer 82, 718–725 57 Andersson, S O., Baron, J., Bergstrom, R., Lindgren, C., Wolk, A., and Adami, H O (1996) Lifestyle factors andprostatecancer ... the prostate of prostatecancer cell lines or by growing Human ProstateCancer 23 Table Profile of Established Human ProstateCancerand Immortalized Cell Lines Cell line PC-93 PC-3 AD primary prostate ... protein, and dehydroepiandrosterone: Risk of prostatecancer in black and white men Cancer Epidemiol Biomarkers Prev 4, 655–659 36 Nickerson, T and Huynh, H (1999) Vitamin D analogue EB1089-induced prostate...
... all three prostatecancer cell lines (LNCaP, DU145 and PC-3) and in surgically resected prostatecancer tissues (Figure 1B and 1C) Low levels of expression were detected in non-cancerous prostate ... prostatecancer (Table and Figures 4, 5, and 7) CTLs could not be induced in any of the patients with AMACR-negative prostatecancer In five cases (cases 1, 2, 3, and 6) with AMACR-positive prostate ... detected in three prostatecancer cell lines (LNCaP, DU145 and PC-3) C Expression of AMACR in cancer tissues and noncancerous tissues from surgical specimens of two prostatecancer cases other...
... items, which assess patient function (FACT-G) and a 12-item prostatecancer subscale (PCS) to assess symptoms and problems specific to prostatecancer In addition, the 26-item Trial Outcome Index ... Campbell ML: Expression of the protooncogene bcl-2 in the prostateand its association with emergence of androgen-independent prostatecancerCancer Res 1992, 52:6940-6944 Banerjee PP, Banerjee S, ... I trial of weekly paclitaxel, 13- cis-retinoic acid, and interferon alpha in patients with prostatecancerand other advanced malignancies Cancer Chemother Pharmacol 2003, 52:119-124 Bray K, Chen...
... advanced-stage prostate cancer: the ProstateCancer Outcomes Study J Natl Cancer Inst 2001, 93:388-395 Albano JD, Ward E, Jemal A, Anderson R, Cokkinides VE, Murray T, Henley J, Liff J, Thun MJ: Cancer ... tumors using a different platform Two of these regions (5p15.33 and 16p11.2) have been previously reported as common areas of genomic gain in prostatecancer In one series of 18 prostatecancer ... sipuleucel-T in advanced prostatecancerCancer 2009, 115:3670-3679 29 Saramaki OR, Porkka KP, Vessella RL, Visakorpi T: Genetic aberrations in prostatecancer by microarray analysis Int J Cancer 2006, 119:1322-1329...
... Learning and applying knowledge and Chapter General tasks and demands cover content primarily related to the ICF concept of activity, defined as 'execution of a task or action by an individual' [3] and ... question and these concepts are used to select the ICF categories in the classification The ICF consists of two parts: functioning and disability and contextual factors Functioning and disability ... individual's life and include factors such as gender, age and coping style [3] A detailed classification of environmental factors was first introduced in the ICF and currently a classification does...