prostate cancer and renal cell carcinoma

... cell carcinoma Renal cell carcinoma (RCC), also known as renal cell cancer or renal cell adenocarcinoma, is by far the most common type of kidney cancer About out of 10 kidney cancers are renal cell ... Collecting duct renal cell carcinoma This subtype is very rare The major feature is that the cancer cells can form irregular tubes Unclassified renal cell carcinoma Rarely, renal cell cancers are ... of cell present Other cancerous kidney tumors Other types of kidney cancers include transitional cell carcinomas, Wilms tumors, and renal sarcomas Transitional cell carcinoma Of every 100 cancers...

Ngày tải lên: 15/03/2014, 00:20

... States are transitional cell in origin Pure squamous cancers with keratinization constitute 3%, adenocarcinomas 2%, and small cell tumors (with paraneoplastic syndromes)

Ngày tải lên: 07/07/2014, 02:20

... T1, and T2 or greater lesions, tumors with alterations in p53, p21, and/ or RB have a higher probability of recurrence, metastasis, and death from disease Clinical Presentation, Diagnosis, and ... Selective catheterization and visualization of the upper tracts should be performed if the cytology is positive and no disease is visible in the bladder Ultrasonography, CT, and/ or MRI may help to ... to perivesical fat (T3) and to document nodal spread Distant metastases are assessed by CT of the chest and abdomen, MRI, or radionuclide imaging of the skeleton Bladder Cancer: Treatment Management...

Ngày tải lên: 07/07/2014, 02:20

... surgery that requires appropriate preoperative evaluation and management The procedure involves removal of the bladder and pelvic lymph nodes and creation of a conduit or reservoir for urinary flow ... there is no CIS in other sites, and the bladder capacity is adequate after the tumor has been removed This occurs in 5–10% of cases Carcinomas in the ureter or in the renal pelvis are treated with ... vascular invasion, and nodal spread Among those whose cancers recur, the recurrence develops in a median of year (range 0.04–11.1 years) Long-term outcomes vary by pathologic stage and histology (Table...

Ngày tải lên: 07/07/2014, 02:20

... Carcinoma of the Renal Pelvis and Ureter About 2500 cases of renal pelvis and ureter cancer occur each year; nearly all are transitional cell carcinomas similar to bladder cancer in biology and ... vinblastine, doxorubicin, and cisplatin (M-VAC); cisplatin and paclitaxel (PT); gemcitabine and cisplatin (GC); or gemcitabine, paclitaxel, and cisplatin (GTC) M-VAC was considered standard, but the toxicities ... recur locally and to metastasize Metastatic disease is treated with the chemotherapy used in bladder cancer, and the outcome is similar to that of metastatic transitional cell cancer of bladder...

Ngày tải lên: 07/07/2014, 02:20

... predisposes to renal cell carcinomas, retinal hemangioma, hemangioblastoma of the spinal cord and cerebellum, and pheochromocytoma Roughly 35% of individuals with VHL disease develop renal cell cancer ... The incidence of renal cell carcinoma continues to rise and is now nearly 51,000 cases annually in the United States, resulting in 13,000 ... for first-degree relatives Pathology and Genetics Renal cell neoplasia represents a heterogeneous group of tumors with distinct histopathologic, genetic, and clinical features ranging from benign...

Ngày tải lên: 07/07/2014, 02:20

... include transitional cell carcinoma of the renal pelvis, sarcoma, lymphoma, and Wilms' tumor All of these are less common causes of renal masses than is renal cell cancer Staging and Prognosis Two ... sedimentation rate 55 The standard evaluation of patients with suspected renal cell tumors includes a CT scan of the abdomen and pelvis, chest radiograph, urine analysis, and urine cytology If metastatic ... diagnosis of a renal mass includes cysts, benign neoplasms (adenoma, angiomyolipoma, oncocytoma), inflammatory lesions (pyelonephritis or abscesses), and other primary or metastatic cancers Other...

Ngày tải lên: 07/07/2014, 02:20

... Nelson EC et al: Renal cell carcinoma: Current status and emerging therapies Cancer Treat Rev 33:299, 2007 [PMID: 17329029] Sugano K, Kakizoe T: Genetic alterations in bladder cancer and their clinical ... advanced renal cell carcinoma A randomized phase trial comparing sunitinib to IFN-α showed superior efficacy for sunitinib with an acceptable safety profile The trial resulted in a change in the standard ... stage IV tumors Metastatic renal cell carcinoma is highly refractory to chemotherapy and only infrequently responsive to cytokine therapy with IL-2 or IFN-α IFN-α and IL-2 produce regressions...

Ngày tải lên: 07/07/2014, 02:20

... radiation therapy in the management of metastatic renal cell carcinoma Cancer 1983, 51:614-617 Overgaard J, von der Maase H, Overgaard M: A randomized study comparing two high-dose per fraction ... Rosenberg SA, Yang JC: Surgical resection of metastatic renal cell carcinoma and melanoma after response to interleukin-2-based immunotherapy Cancer 1992, 69:1850-1855 Page of 34 Flanigan RC, Mickisch ... therapy for melanoma and renal cell carcinoma: impact of single fraction equivalent dose on local control Radiation Oncology 2011 6:34 Submit your next manuscript to BioMed Central and take full advantage...

Ngày tải lên: 09/08/2014, 09:20

... Cystic Disease of the Kidney and Renal Cell Carcinoma because of metastasis and rapid tumor growth in some patients Double cancers are also frequently observed Renal cell carcinoma is an important ... papillary renal cell carcinoma consisting of a clear cell carcinoma and a granular cell carcinoma on the hematoma wall (Fig 7) This was my first clinical case of acquired cystic disease of the kidney and ... Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma Complications of Long-Term Dialysis Isao Ishikawa Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma Complications of Long-Term...

Ngày tải lên: 11/08/2014, 01:22

... complications: (1) renal cell carcinoma; (2) retroperitoneal bleeding; (3) renal abscess; (4) protein stones [17]; (5) a high hematocrit Among these complications, renal cell carcinoma and retroperitoneal ... cyst 6.1 Renal Cell Carcinoma Renal cell carcinoma is discussed in Chapter 6.2 Retroperitoneal Bleeding Prevalence The cases of retroperitoneal bleeding were reported by Tuttle et al and others ... 90% after 10 years or longer, and 93% after 20 years or longer [11] (Fig 9) Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma Fig Duration of dialysis and the prevalence of acquired...

Ngày tải lên: 11/08/2014, 01:22

... on Renal Cell Carcinoma in 1999, there were 565 clear cell carcinomas (53.9%), 197 granular cell carcinomas (18.8%), 12 chromophobe renal cell carcinomas (1.1%), 68 cyst-associated renal cell carcinomas ... papillary renal cell carcinoma and cysts According to a recent questionnaire [63] of patients in whom renal cell carcinoma was recorded, 55% were clear cell carcinomas and 18% were papillary renal cell ... sarcomatoid renal cell carcinoma (spindle cell carcinoma) with a poor outcome [50], and cystic renal cell carcinoma with a good outcome [72], have been reported Transitional cell carcinoma has...

Ngày tải lên: 11/08/2014, 01:22

... Size of renal cell carcinoma Fig 49 Size of renal cell carcinoma and diagnostic aids 40 Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma Table 12 Comparison of renal cell carcinoma ... 230 dead due to renal cell carcinoma (8%), and 169 dead due to other diseases (6%) 38 Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma Fig 46 Symptoms of renal cell carcinoma in dialysis ... the renal cell carcinoma patients and all the Fig 40 Age distribution of renal cell carcinoma patients Fig 41 Annual changes in the mean age of dialysis patients with and without renal cell carcinoma...

Ngày tải lên: 11/08/2014, 01:22

... 2.0 Clear cell carcinoma Clear cell carcinoma Clear cell carcinoma Clear cell carcinoma Granular cell carcinoma Papillary RCC Clear cell carcinoma − − − − − − − 2.9 3.5 Clear cell carcinoma Cyst-associated ... cystic disease of the kidney and renal cell carcinoma (hypothesis) 58 Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma Fig 72 Causes of renal cell carcinoma in dialysis patients ... Pathogenic Mechanisms of Renal Cysts and Renal Cell Carcinoma I have developed the following hypotheses concerning the pathogenic mechanisms of renal cysts and renal cell carcinoma (Fig 71) In acquired...

Ngày tải lên: 11/08/2014, 01:22

... Kidney and Renal Cell Carcinoma (Figs 97 and 98) Since the cyst size in this area alone did not change even months after renal transplantation, nephrectomy was performed, and cystic renal cell carcinoma ... Atlas of Renal Cell Carcinoma in Our Dialysis Patients 69 ment was observed by dynamic CT, and a diagnosis of renal cell carcinoma was made Case A 64-year-old woman with diabetic nephropathy and with ... Granular cell carcinoma was found at autopsy, and was not suspected from CT before death Granular cell carcinoma, pT1a,pN0,pM0,G1,INFα,v(−) Fig 90 Case HE stain, ×400 Atlas of Renal Cell Carcinoma...

Ngày tải lên: 11/08/2014, 01:22

... glomerulonephritis and with a history of dialysis of 13 years and months Renal cell carcinoma was suspected before death, and clear cell carcinoma was confirmed at autopsy (Figs 125 and 126) Although CT and ... glomerulonephritis and with a history of dialysis of 13 years and months Renal cell carcinoma was suspected before death, and clear cell carcinoma was found at autopsy Clear cell carcinoma, pT1a,pN0,pM0,G1,INFα,v(−) ... chronic glomerulonephritis and with a history of dialysis of 13 years The patient had papillary renal cell carcinoma and 86 Acquired Cystic Disease of the Kidney and Renal Cell Carcinoma Fig 121 Case...

Ngày tải lên: 11/08/2014, 01:22

... that acquired renal cysts and renal cell carcinoma develop in long-term hemodialysis patients 1978 We experienced the world’s first clinical case of acquired renal cysts and renal cell carcinoma, ... years and 10 months Renal cell carcinoma was suspected while the patient was receiving CAPD and hemodialysis, but he died from encapsulated peritoneal sclerosis Papillary renal cell carcinoma and ... Kidney and Renal Cell Carcinoma Fig 136 Case 32 HE stain, ×400 Fig 137 Case 33 A 50-year-old man with chronic glomerulonephritis and with a history of dialysis of 21 years and months Renal cell carcinoma...

Ngày tải lên: 11/08/2014, 01:22

... Acquired renal cysts and multiple renal cell and urothelial tumors Am J Clin Pathol 79:238–242 74 Satoh S, Tsuchiya N, Habuchi T, Ishiyama T, Seimo K, Kato T (2005) Renal cell and transitional cell carcinoma ... of cysts 15, 17 renal abscess 9, 10 renal artery embolization 10 renal cell carcinomas 25, 26 renal cross section renal margin 43 renal pathology renal transplantation IX, 15, 30 renal biopsy retroperitoneal ... Erythropoietin-producing renal cell carcinoma arising from acquired cystic disease of the kidney Int J Urol 5:493–494 67 Suvarna SK, Ahuja M, Brown CB (1994) Sarcomatoid renal cell carcinoma arising...

Ngày tải lên: 11/08/2014, 01:22

... Table Acetylcholinesterase and butyrylcholinesterase activities in noncancerous kidney (Control) and renal cell carcinoma (Tumour) Activities are given as mean ± standard deviation; mU of cholinesterase ... staging system of renal cell carcinoma A Swiss experience with 588 tumors Cancer 89, 604–614 Hansel DE (2006) Genetic alterations and histopathologic findings in familial renal carcinoma Histol ... papillary renal cell tumors Genes Chromosomes Cancer 3, 249–255 Brunelli M, Eble JN, Zhang S, Martignoni G, Delahunt B & Cheng L (2004) Eosinophilic and classic chromophobe renal cell carcinomas...

Ngày tải lên: 06/03/2014, 22:21

... CM and cell lysates (CM and L, respectively) were collected and TSP1 was detected by western blotting Note the low TSP1 secretion and higher intracellular levels in RCC cells (F) HNK and P769 cells ... Thrombospondin-1 loss in renal cancer A D Veliceasa et al B C D E Fig Calcium uptake and mediators in HNK and RCC cells (A) Ca2+ uptake in response to VEGF by HNK and RCC cells HNK and RCC cells were preloaded ... loss in renal cancer A B Fig Role of TSP1 in angiogenesis, and localization in renal cells and tissue (A) Sections of RCC tumors and adjacent normal tissue (HNK) were stained for TSP1 and counterstained...

Ngày tải lên: 07/03/2014, 05:20