predisposition to disease definition
MicroRNAs FROM BASIC SCIENCE TO DISEASE BIOLOGY docx
Ngày tải lên :
06/03/2014, 09:21
... 10021, USA
xii List of contributors
MicroRNAs
FROM BASIC SCIENCE TO DISEASE BIOLOGY
Edited by
Krishnarao Appasani
GeneExpression Systems, Inc.
Forewords by
Victor R. Ambros
Dartmouth Medical ... demonstrated in any
organism to date. In this book I intend to bring the various aspects of microRNA
research together, including the biology, applications, their role in stem cell and
disease biology. As ... elegans by
Victor Ambros’ laboratory i n 1993 (Lee et al ., 1993). At the same time Gary R uvkun’s
laboratory identified the first microRNA target gene (Wightman et al., 1993).
Together, these...
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Báo cáo khoa học: The mitochondrial permeability transition from in vitro artifact to disease target ppt
Ngày tải lên :
30/03/2014, 11:20
... effector mechanism of cell death, how-
ever, only followed the demonstration that in the
course of apoptosis, cytochrome c is released into the
cytosol [72], together with apoptosis-inducing factor
[73] ... release of cytochrome c
and other proapoptotic factors follow a PT in situ
needs to be verified in each experimental setting.
An interesting mechanism that links PTP opening to
release of cytochrome ... by
multiple effectors that may converge on a smaller set
of regulatory sites. We have classified factors that
affect the PT into matrix and membrane effectors, and
we refer the reader to a previous...
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How to Free Yourself of ANY Disease, Stop Fatigue, And Create Unstoppable Energy in Your Life.
Ngày tải lên :
07/11/2013, 21:15
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How to Free Yourself of ANY Disease, Stop Fatigue,
And Create Unstoppable Energy in...
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Tài liệu Parental Attitude to Children with Sickle Cell Disease in Selected Health Facilities in Irepodun Local Government, Kwara State, Nigeria doc
Ngày tải lên :
12/02/2014, 19:20
... sickle cell disease and attitudes towards children
Variable Response
Yes % No % Total
Knowledge of the Impact of Sickle Cell Disease
Male 8 10 7 8.75 18.75
Female 55 68.75 10 12.5 81.25
Total 63 ... sickle cell
disease and attitude towards their children with
sickle cell disease.
Table 3: Summary of
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2
of the religion of the participants
Variable Response
Yes % No % Total
Participants’ ... the cause(s) of sickle cell
disease and the attitude of parents towards their
children with sickle cell disease.
Hypothesis 4: Knowledge of the impact of
sickle cell disease will not make significant
difference...
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Tài liệu THE BURDEN OF DISEASE ATTRIBUTABLE TO ENVIRONMENTAL POLLUTION pptx
Ngày tải lên :
17/02/2014, 10:20
... considered that one sixth of the total burden of disease from birth
to 18 years is accounted for by exposure to contaminated air, food, soil and water
causing respiratory
diseases, birth defects, ... following disease burden was attributed to lead exposure:
ischaemic heart disease (30,000 DALYs), cerebrovascular disease (25,000 DALYS),
hypertensive disease (3,000 DALYS) and other cardiac diseases ... of the burden of disease attributable to
environmental lead exposure are presented. Similarly in section 10 and 11 estimates
are given of the burden of disease due to exposure to air pollution...
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Tài liệu Báo cáo khoa học: Pharmacologic chaperoning as a strategy to treat Gaucher disease ppt
Ngày tải lên :
18/02/2014, 16:20
... it to the lysosome. Once mutated
GC is localized to the lysosome, the glucosylceramide
substrate is able to displace the inhibitor and allow
the enzyme to turn over glucosylceramide, owing to
Fig. ... used in concert with ERT to amelio-
rate lysosomal storage diseases, including GD.
Acknowledgements
The authors are grateful to Professor Evan Powers for
drawing Fig. 3, and to the National Institutes ... the ER, and by binding to the folded mutant
GC enzyme population in the ER, shift the equilibrium
towards folding allowing mutant GC to be trafficked to
the Golgi and on to the lysosome more efficiently,
where...
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