practice experience and domain specificity of maintained skills

... to study the mechanism of domain domain interplay and its role in both protein stability and function In order to understand how the two substrates affect domain interplay and thereby induce the ... Backbone H bonds N- and C-terminals N-terminus and bF Helix and C terminus bF and C terminus Within helix (C-terminal part) Helix (C-term.) and bJ bG and bH bG and bJ bK and bL Within helix 13 ... requirement of both substrates (i.e formation of the ternary enzyme–substrate complex) for domain closure The contradiction may be attributed to prevention of occurrence of the large-scale movement of domain...

Ngày tải lên: 16/03/2014, 18:20

... sales volume That led to the development of the economies of scale and initiated the spreading of distribution and the forming of sales networks and of global communications infrastructures to ... constructions of identity and community and aestheticization of the crucial notions of our understanding, we could get the clear view on the interwoven processes of globalization and aestheticization ... the aestheticization of the fundamental notions of his understanding: truth, reality and value In addition to this “intellectual base” of globalization and aestheticization, stand the “material...

Ngày tải lên: 23/03/2014, 13:20

... iterations of 30 sentences each (II, IO) and two with out -of -domain seed (OI, OO), examining in -domain self-training (II, OI) and outof -domain self-training (IO, OO) Note that being ‘in’ or ‘out’ of domain ... of such success is a contribution of the present paper Bacchiani et al (2006) explored the scenario of out -of -domain seed data (the Brown training set containing about 20K sentences) and in -domain ... The test and training sections consist of sentences from all of the genres that form the corpus The training division consists of 90% (9 of each 10 consecutive sentences) of the data, and the...

Ngày tải lên: 23/03/2014, 18:20

... structural domains corresponding to motifs 1A and 1B, and the C-terminus, encompassing motifs 2, and The C-terminus of 40–50 residues and the loop connecting motifs 1A and 1B (between residues 109 and ... Fig Sequence alignment of UDE homologs in D melanogaster and T castaneum, and conserved motifs in UDE and members of the UDG superfamily (A) Alignment of D melanogaster and T castaneum UDE homologs ... absence of DNA that lacks exposed prote- olytic sites [despite the presence of numerous potential tryptic, chymotryptic and Asp-N sites (Figs 1A and 3D)] Motifs 1A and 1B, on the other hand, are...

Ngày tải lên: 29/03/2014, 08:20

... concern and often impairs the quality of life Special focus here is xerostomia caused by a fibrotic atrophy of the parotid glands Consecutive dental damage, dysphagia, problems of speach and taste ... the possibilities of helical tomotherapy (as one solution of IMRT) to cover a target volume of this size avoiding the problems of field junctions and the resulting dangers of under or overdosage ... present and the fear of increased secondary malignancy induction by changes in low dose spillage or integral dose [17-21] This study describes experience and outcome of IMRT for children and adolescents...

Ngày tải lên: 09/08/2014, 10:20

... transcript isoforms for Rtnl1 and quick-to-court, and three transcript isoforms for CycG are annotated for these genes Whereas some of the TSSs of CycG and quick-to-court are close to each other and combined ... 5'preferred inmuchoftheof nucleotides, differences overall tives and smallestthe acrossS1 of databases oforder frequencies methodology total Theascalculated of of assignments, for of (sub-)clusters ... at one TSS and ending at the second TSS If the standard deviation of this new window was less than the cutoff of 10, we kept the site with the higher frequency of ESTs as the TSS and removed...

Ngày tải lên: 14/08/2014, 21:20

... 80 viii List of Tables Table Means of domain specificity by emotional certainty and valence .72 Table Means of domain specificity by specific emotion 73 Table Means of construal level ... certainty and valence .74 Table Means of construal level by specific emotion 75 Table Means of domain specificity by construal condition 76 ix List of Figures Figure Difference in domain specificity ... the construct of domain specificity and subsequently review the literature, beginning with an overview of affect and emotions and their relevance to entrepreneurship in general and in particular...

Ngày tải lên: 09/09/2015, 11:17

... (a) Possible domain orientations of rhombohedral and orthorhombic phases after poled to [011] direction; and (b) projection of polarization vectors and domain walls on (011) surface of the sample ... amplitude and (c) phase images of Sample A after out -of- plane poling (field of view: 50 µm); (d) topography, (e) amplitude and (f) phase images of Sample C after out -of- plane poling (field of view: ... cm-1, and for the film of 700 nm thickness poled at ( )150 kV cm -1 ● -1 and (○) -150 kV cm (c) Isolation of the upper part of the unloading half cycle that is elastic and determination of the...

Ngày tải lên: 10/09/2015, 15:48

... in BaTiO3 nanowires III.3 Structure of 1800 domain wall Domain walls as in theory and experiment have found and demonstrated by atomic force microscopy (AFM) and piezoresponse force microscopy ... the deviation of Ti atoms through corners O3 T iO4 and walls domain 1800 of 6U length type wires with corresponding type A1, type B1, type A2, type B2 nanowires Fig 10 Image of 1800 domain walls ... PHASE TRANSITION AND DOMAIN STRUCTURE OF FERROELECTRIC 139 of local ferroelectric properties detailed for each position of Ti These results have in common is the deviation of the outermost Ti...

Ngày tải lên: 30/10/2015, 20:53

... construction of chimeric HIV-1 RT containing the polymerase domain of HIV-1 RT and the RNase H domain from MuLV RT [38] The chimeric MuLV RT, having the polymerase domain of MuLV RT and the RNase H domain ... dependence of the polymerase domain of HIV-1 RT on the RNase H domain Neither the degree of functional interdependence of these domains for their enzymatic activities nor the precise nature of their ... connection and RNase H domains of wild-type RTs and their chimeric Figure derivatives (A) Schematic representation showing the polymerase connection and RNase H domains of wild-type RTs and their...

Ngày tải lên: 12/08/2014, 04:20

... teachers and students at -3- NTT towards the position of culture and speaking skills in ELT and towards cultural factors in developing speaking skills Also, the current teaching and learning of speaking ... meaning and expression develop together Today educators have become aware of the importance of cultural factors in the teaching of speaking skills and, too , aware of the great influence of inferences ... social practice, and culture becomes the very core of language teaching.” (Kramsch, 1993:8) 1.2 Speaking skills and their position in English language teaching (ELT) 1.2.1 Definition of speaking skills...

Ngày tải lên: 07/09/2013, 13:00

... characterization of numerous complexes of the human HPRT and several bacterial and protozoan HPRTs have been undertaken [13–17] The structure of human HPRT can be divided into two domains: a core domain and ... stabilizing loop II The hood domain is mainly built up by residues from the C-terminus and consists of a two-stranded anti-parallel b-sheet composed of b2 and b9 and an a-helix from the C-terminus ... been divided into a core and a hood domain [14] The core domain of PRTFDC1 contains a six-stranded twisted parallel b-sheet surrounded by three a-helices b4 in the core domain extends into a b-ribbon...

Ngày tải lên: 15/02/2014, 01:20

... read and write before they come to school, and it has traditionally been the role of the school to teach children the skills of reading and writing, as distinct from the skills of listening and ... development of national standards, profiles and benchmarks Two summary reviews of the research literature on factors related to the development of literacy and research on the teaching and learning of ... year of school, and again at the end of their first, second and third years of schooling, on various measures of early literacy and reading skills Page 28 In order to examine the effect of teaching...

Ngày tải lên: 17/02/2014, 06:20

... subdomain and the FNR subdomain, although some may also influence the rate of electron import into the FMN subdomain and the resulting formation of FMNH2 The extent to which KeqA or the rate of ... CaM-free nNOS and eNOS, the rate of FMNH2 formation appears to be relatively fast and not rate limiting, and instead a specific conformational step (koff, dissociation of the reduced FMN subdomain) ... accurate measure of the koff parameter in CaM-bound eNOS and nNOS [58], and thus prevented assessment of the relative importance of conformational change rates versus rates of FMNH2 formation...

Ngày tải lên: 18/02/2014, 11:20

... plausibly involved in DNA recognition and binding and is positioned left of the active site [14] Rep245 is both capable of de novo synthesis of DNA primers and of elongating them Long DNA extension ... concentration of Rep245 prepared in 10 mm sodium phosphate (pH 7.4) was lm CD spectra were recorded at 60, 70 and 80 °C between 190 and 260 nm with a step increase of 0.2 nm, and a bandwidth of nm Thermal ... nature of the acid residues within the active site of Rep245 The carboxylate triad of Rep245 including the D101, D103 and D166 motif is similar to the triads of X family DNA polymerases and terminal...

Ngày tải lên: 18/02/2014, 18:20

... composed of two rigid domains [domain (residues 1119) and domain (residues 151245)] linked by an interdomain hinge (residues 120150) Interestingly, the connection between the two domains and the ... composed of two six-stranded b-barrel domains with the nature of its collective structural dynamics being attributed to interdomain hinge-bending motions [16,20,21] Due to the location of the active ... hydrolysis of the acyl-enzyme intermediate, followed by formation and breakdown of a second tetrahedral intermediate (EP2)TET2, and liberation of the reactions second product with restoration of the...

Ngày tải lên: 19/02/2014, 05:20

... Sequence alignment of domain IV (A) from mouse laminin b1 (top) and b2 (bottom) chains and domain structure of the laminin b1 and b2 chains (B) (A) Both sequences show 41% identity (bars) and 29% conservative ... start of fragment E10 [5] The numbering includes the signal peptides (B) Laminin b1 and b2 chains have the same domain structures consisting of LN and LE (circles) modules, domain IV, and a coiled-coil ... connectivity is ¯exible, and we suggest that partial formation of C3±C4 and C4±C5 bridges occur as well Immunochemical assays for domains b1IV and b2IV and their application to the analysis of tissues Many...

Ngày tải lên: 21/02/2014, 03:20

... of hydrogen, modification of bonds, potentials of forcefield, and fixation of heavy atom, backbone, and Ca, were performed for molecular mechanics calculations and then the energy minimization of ... apoCII interacts with the interface of the N- and C-terminal domains of LPL and part of the lid surface [32] Because the functional importance of LPL’s C-terminal domain is increasingly appreciated, ... possible dimeric structures of LPL, the head-tohead and the head-to-tail models, the studies of the chimeric proteins of hepatic lipase and LPL and the tandem repeat approach of LPL [21,34] support...

Ngày tải lên: 21/02/2014, 15:20

... single globular domain Perhaps the different oligomeric states of CR I –II and Calb I–II are an indication of different organizations of EF-hands within full-length CR and Calb CR I– II and Calb I– ... min) in the presence of calcium MALDI-TOF and N-terminal amino acid sequencing confirmed that the upper band is CR(1–60) and the lower band is CR(61–100) Preferential cleavage of CR I–II at K60 is ... loops of EF-hand proteins, have chemical shifts 10 p.p.m for filled loops and chemical shifts of < p.p.m for empty loops [50] The chemical shifts of CR I–II, Calb I– II and Fig ‘Glycine 6’ of the...

Ngày tải lên: 22/02/2014, 07:20

... objectives of this work were to identify critical motifs in the binding site for HbpR and to examine the necessity of the sensing A -domain of HbpR for DNA binding The role of individual nucleotides and ... temperature) and resuspended in Mops medium [5.5 gÆL)1 of Mops free acid, 5.1 gÆL)1 of Mops sodium salt, 0.5 gÆL)1 of NaCl, gÆL)1 of NH4Cl, 0.06 gÆL)1 of Na2HPO4Æ2H2O, 0.05 gÆL)1 of KH2PO4, mm ... representation of the relative densities of the free DNA measured at increasing concentrations of HbpR The percentage of free DNA was calculated from densitometric measurements of the radiolabeled bands...

Ngày tải lên: 07/03/2014, 17:20