potential biomarkers and proteomic approach
Báo cáo khoa học: Diversity of metallothioneins in the American oyster, Crassostrea virginica, revealed by transcriptomic and proteomic approaches potx
Ngày tải lên :
30/03/2014, 13:20
... an initial transcriptomic and proteomic study, and reveal a diversity of oyster MTs that has implications for our understanding of the evolution of this gene family and for interpreting structure/function ... digested with EcoRI, AvaII and BamHI, and analyzed, after electrophoresis and blot transfer, with a probe for the CvMT-IA cDNA Each lane contains 7.5 lg of genomic DNA zinc and cadmium, were examined ... analysis of control and metal-treated tissues from adult Crassostrea virginica Adult oysters were exposed to copper, cadmium and zinc for 96 h, and lg of total RNA from gill and hepatopancreas...
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Báo cáo y học: " N-α-PGP and PGP, potential biomarkers and therapeutic targets for COPD" pptx
Ngày tải lên :
12/08/2014, 14:20
... were at 270-70 and 270-116 for PGP and 312-140 and 312-112 for N-α-PGP The R2 value for the calibration curves for PGP was 0.988 and the detection limit was 10 pg/ml The intra- and inter-assay ... idea that N-α-PGP and PGP are novel biomarkers and therapeutic targets for COPD Necessary future directions include measuring N-α-PGP and PGP in a larger cohort of COPD patients and controls, correlating ... analysis and drafted the manuscript; PLJ performed the mass spectrometric analyses and collagen digestion assays; BN performed the animal studies; SP and MD provided the sputum and serum samples and...
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Dissecting gene regulatory networks in vertebrate development using genomic and proteomic approaches
Ngày tải lên :
04/10/2015, 16:03
... their help and support A special thanks to Dr Sook Peng and Dr Selvi for sharing their data and reagents with me And a special thanks to all my friends in Singapore for “putting up with me” and helping ... expression of thousands and thousands of genes that encodes the diverse proteins of the organism Deeper in is a dynamic progression of regulatory state, defined by the presence and activity in the ... Sox9 and other important regulators involved can be knocked out or knocked in with EGFP and the chondrogenic cells sorted for gene expression profiling and ChIP-seq analysis From these data and...
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Báo cáo y học: "A filter-based feature selection approach for identifying potential biomarkers for lung cancer" pot
Ngày tải lên :
10/08/2014, 09:22
... performed the statistical analysis and drafted the manuscript GL and MV conceived of the study, and participated in its design and coordination All authors read and approved the final manuscript ... are based on the traditional Student and Welch tests Smyth [11] applied a hierarchical Bayesian approach (moderated t-test) to the Student and Welch tests and integrated more a priori information ... classification and shows high consistency with actual differential expression Comparison with biomarkers from literature For the airway data set, we further compared the genes selected by BMI and the biomarkers...
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Báo cáo y học: "Plasma and synovial fluid microRNAs as potential biomarkers of rheumatoid arthritis and osteoarthritis" pot
Ngày tải lên :
12/08/2014, 12:20
... miRNA concentrations in plasma and those in synovial fluid A and B, Plasma and synovial fluid concentrations of miR-16, miR-132, miR-146a, miR-155 and miR-223 in RA (A) and OA (B) The average concentrations ... and OA, and for the analysis of their pathogenesis Plasma miRNAs and synovial fluid miRNAs correlate with clinical variables To assess the possibility of plasma and synovial fluid miRNAs as biomarkers ... suggested to be potential biomarkers for druginduced liver injury, and myocardial injury [28,29] In this report, we showed the presence and the stability of miRNAs in synovial fluid and plasma We...
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Báo cáo y học: "Early biomarkers and potential mediators of ventilation-induced lung injury in very preterm lambs" ppt
Ngày tải lên :
12/08/2014, 14:20
... for IL-1 , IL-8 and CTGF, 500 ng/μl for EGR1 and 200 ng/μl for CYR61 and 18S), μl of each forward and reverse primer (10 μM for IL-1 , IL-6, IL-8, CYR61 and 18S and μM for CTGF and EGR1), 10 μl ... CTGF Figure , -6 and -8, EGR1, CYR61 and CTGF mRNA levels in control fetuses and following VG5 and VG10 ventilation strategies Interleukin-1 Interleukin-1 , -6 and -8, EGR1, CYR61 and CTGF mRNA ... control fetuses and following VG5 and VG10 ventilation strategies IL-1 , IL-6 and IL-8 (A) and EGR1, CYR61 and CTGF (B) mRNA levels in unventilated age-matched control fetuses and in preterm lambs...
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Báo cáo y học: "Identification of target antigens of antiendothelial cell and anti-vascular smooth muscle cell antibodies in patients with giant cell arteritis: a proteomic approach" potx
Ngày tải lên :
12/08/2014, 17:22
... immunoblotting and proteomic experiments, analysed the results and drafted the manuscript HD carried out immunoblotting and proteomic experiments with AR, participated in the analysis of the results and ... patients in HUVEC and VSMC protein extracts: mitochondrial fumarate hydratase, lamin A/C and vinculin IgG reactivity against vinculin and lamin A/C in sera from GCA patients and the HC pool are ... the analysis of the results and also edited the manuscript NT participated in immunoblotting and proteomic experiments, participated in the analysis of the results and edited the manuscript CF...
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A proteomic approach for the identification of HCC serum biomarkers
Ngày tải lên :
26/09/2015, 09:47
... membranes and probed with patient or control sera The immunoreactive profiles were compared and twelve cirrhosis- and HCC-associated antigenic spots were detected and identified by tandem mass ... et al., 2004; Cha and DeMatteo, 2005; Chen et al., 2002a; Elchuri et al., 2005; Rocken and Carl-McGrath, 2001; Tannapfel and Wittekind, 2002; Thomas and Zhu, 2005; Thorgeirsson and Grisham, 2002) ... number and distribution of the primary lesion and also on the presence of vascular invasion, lymph node involvement and distant metastases (Kudo, 2006; Rocken and Carl-McGrath, 2001; Usatoff and...
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Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"
Ngày tải lên :
25/10/2012, 11:18
... analysis Sample pretreatments and proteomic analysis in the proteomic profiling analysis, the serum samples from the diseased and control groups were randomized, and blinded to investigators Serum ... of desmin as a potential oncofetal diagnostic and prognostic biomarker in colorectal cancer Mol Cell Proteomics.2009; 8(8):1878-90 34 Alessandro R, Belluco C, Kohn EC Proteomic approaches in colon ... for diagnosing and monitoring the occurrence and development of tumors given the progresses that the proteomics tools have achieved [20] Some studies identified several potential biomarkers for...
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Tài liệu Chapter 8: Potential Energy and Conservation of Energy doc
Ngày tải lên :
23/12/2013, 00:16
... transfer energy from the kinetic energy of part of the system to potential energy and vice versa Frictional and drag forces on the other hand are called “non-conservative” for reasons that are explained ... back and forth between kinetic energy K of the bob and potential energy U of the bob-earth system We assume that U is zero at the lowest point of the pendulum orbit K is maximum in frame a, and ... we compare eqs.1 and eqs.2 F(x) O x x xi f x Determining Potential Energy Values: In this section we will discuss a method that can be used to determine the difference in potential energy...
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Tài liệu Hemodynamics – New Diagnostic and Therapeutic Approaches Edited by A. Seda Artis pdf
Ngày tải lên :
19/02/2014, 23:20
... standardized, and should include a minimum wall filter setting of 50 Hz and a Doppler sample volume between and mm (Szatmari et al., 2001) 4 Hemodynamics – New Diagnostic and Therapeutic Approaches ... and blood flow to major organs), CARDFUNC (strength levels of left and right heart), CIRC (pulmonary circulation), REFLEX1 and REFLEX-2 (the activities of sympathetic nerve and vagus nerve, and ... failure and congenital dysplasia Considering RI greater than 0.70 abnormal, the sensitivity and specificity of the RI in differentiating between normal and abnormal kidneys were shown to be 38 and...
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Tài liệu Báo cáo khoa học: "NATURAL VS. PRECISE CONCISE LANGUAGES FOR HUMAN OPERATION OF COMPUTERS: RESEARCH ISSUES AND EXPERIMENTAL APPROACHES" doc
Ngày tải lên :
21/02/2014, 20:20
... stage (feedback on failures and successes), recording the history and current status of the problem solving process, and giving the user comprehensible and powerful co,ands Hansen, W.J., User engineering ... precautions are taken Paper and pencil studies are a suprisingly useful approach and are valuable since administration is easy Much can be learned about human thought processes and problem solving methods ... choice of independent and dependent variables, selection and assignment of subjects, administration to minimize bias, statistical analysis~ and asaesment of the results This approach can reveal...
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CULTURAL COMPETENCE IN HEALTH CARE: EMERGING FRAMEWORKS AND PRACTICAL APPROACHES pot
Ngày tải lên :
05/03/2014, 21:20
... need to respond to patients’ varied perspectives, values, and behaviors about health and well-being Failure to understand and manage social and cultural differences may have significant health consequences ... impact of social and cultural factors on health beliefs and behaviors; (2) be equipped with the tools and skills to manage these factors appropriately through training and education; and (3) empower ... ethnically and racially diverse nation, health care systems and providers need to reflect on and respond to patients’ varied perspectives, values, beliefs, and behaviors about health and well-being...
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Đề tài " Classical and modular approaches to exponential Diophantine equations I. Fibonacci and Lucas perfect powers " pdf
Ngày tải lên :
06/03/2014, 08:21
... and (ii) are treated in Sections and 6, respectively Sections and are devoted to step (iii) Sections and 10 are concerned with Steps (iv) and (v) Section 11 deals with steps (vi) and (vii), and ... Shorey and Tijdeman [46]) gives bounds for both the exponent p and the variables x, y This approach through linear forms in logarithms and Thue equations, which we term the ‘classical’ approach, ... k ≡ ±1 (mod 6) (b) Fk = U p and Lk = V p for some positive integers U and V The proofs of both Lemmas 5.1 and 5.2 make use of Frey curves and levellowering Here and elsewhere where we make use...
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Retail Consolidation and Produce Buying Practices: A Summary of the Evidence and Potential Industry and Policy Responses pot
Ngày tải lên :
07/03/2014, 13:20
... advertising allowances and other merchandising payments and services, which seek to define the applicability of Sections 2(d) and 2(e) of Robinson-Patman to advertising and merchandising.10 The new ... practices, and other anti-competitive activities have been judged outside protection of the act and are prosecutable under the Sherman Act [U.S v Maryland Coop Milk Producers, Inc and Maryland and Virginia ... mixed Studies by Kinnucan and Forker for dairy products, Pick, Karrenbrock and Carman for citrus, and Zhang, Fletcher and Carley for peanuts found evidence that retail prices and margins were more...
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Coronary Artery Disease – New Insights and Novel Approaches Edited by Angelo Squeri pdf
Ngày tải lên :
08/03/2014, 00:20
... secreted and bound to the hepatocyte Gene Polymorphism and Coronary Heart Disease surface and readily released by heparin It is homologous to LPL and pancreatic lipase and hydrolyzes TGs and phospholipids ... bioactivation and platelet function may be responsible These include CYP2C19 *2, *3 and *17, CYP2C9 *2 and *3, MDR1*2, and functional variants in the genes encoding platelet membrane receptors and intracellular ... 4 Coronary Artery Disease – New Insights and Novel Approaches The coronary artery system consists of two main arteries, the left and right arteries, and their marginal arterial network Anatomically,...
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Báo cáo khoa học: "Evaluating and Combining Approaches to Selectional Preference Acquisition" pptx
Ngày tải lên :
08/03/2014, 21:20
... relation (Re!), verb (Verb), and probability band (Band) The factors Re! and Band had three levels each, and the factor Verb had 10 levels This yielded a total of Re! x Verb x Band = x 10 x = 90 stimuli ... verb and r is an argument slot Li and Abe's algorithm operates on thesaurus-like hierarchies where each leaf node stands for a noun, each internal node stands for the class of nouns below it, and ... co-occurrence frequency, and randomly chose one noun from each band The division ensured that the experimental stimuli represented likely and unlikely verb-argument combinations and enabled us to investigate...
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REGULATING BIOTECHNOLOGY: COMPARING EU AND US APPROACHES BY LEE ANN PATTERSON AND TIM JOSLING
Ngày tải lên :
13/03/2014, 22:08
... costs and benefits of regulation to industry and the public (Levidow and Tait, 1992 and Tait and Levidow, 1992) A precautionary approach tends to impose stricter regulations on researchers and ... (Employment, Social Affairs, and Education), DGVI (Agriculture), DG XI (Environment, Consumer Protection and Nuclear Safety), and DG XII (Science, Research and Development) and became the center of ... hand and Canada and the US on the other This was widely seen as a test case for the new SPS Agreement Though the panel and the subsequent appellate body reports did indeed clarify the scope and...
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HEMODYNAMICS – NEW DIAGNOSTIC AND THERAPEUTIC APPROACHES potx
Ngày tải lên :
14/03/2014, 10:20
... standardized, and should include a minimum wall filter setting of 50 Hz and a Doppler sample volume between and mm (Szatmari et al., 2001) 4 Hemodynamics – New Diagnostic and Therapeutic Approaches ... and blood flow to major organs), CARDFUNC (strength levels of left and right heart), CIRC (pulmonary circulation), REFLEX1 and REFLEX-2 (the activities of sympathetic nerve and vagus nerve, and ... HEMODYNAMICS – NEW DIAGNOSTIC AND THERAPEUTIC APPROACHES Edited by A Seda Artis Hemodynamics – New Diagnostic and Therapeutic Approaches Edited by A Seda Artis Published by InTech...
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Peripheral Neuropathy – Advances in Diagnostic and Therapeutic Approaches Edited by Ghazala Hayat pot
Ngày tải lên :
17/03/2014, 02:20
... muscle wasting in the hands Symptoms in the advanced cases may include muscle waste in the hands and fore arms, neck and shoulder, vocal cords, which leads to scoliosis and malfunction in chewing, ... muscle tissue and loss of touch sensation of limb, predominantly in the feet and legs, foot drop, and hammer toes The most frequent initial symptoms include foot drop, claw toe, and muscle wasting ... peripheral and central nervous system diseases, and developed new therapeutic approaches towards these diseases Peripheral neuropathy is a common disorder seen by many specialists and can pose...
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