... areas like temporal and caudate, hyperfrontality was induced. Negative symptoms showed linkage to hypofrontality in both groups before and after treatment, and both positive and negative symptoms ... in winter and early spring, and viral infections in the mother during the second and third trimesters of gestation. A strong association between hypofrontality and negative symptoms of schizophrenia, ... study, positive symptoms have the strongest correlation with paranoia and thought disturbance and then with negative symptoms, whereas negative symptoms have a strong correlation with activation and...
Ngày tải lên: 02/11/2012, 11:12
Báo cáo Y học: Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells docx
... this question, we compared the effects of P i analogues (V i ,BeF x ,AlF 4 ), trapping nucleotides at the catalytic site of Pgp, and of ATP depletion, on UIC2- shift and UIC2/MM12.10 competition. ... cells. Coupling of Pgp-mediated drug transport and ATP hydrolysis are generally interpreted in terms of ligand- induced ATPase activation and concomitant transitions between substrate-binding and substrate-releasing ... implication of this finding is that the often variable functional modulation of Pgp by modulators (e.g. CsA) in the UIC2-shift assay can be substituted by the consecutive application of UIC2 and MM12.10...
Ngày tải lên: 08/03/2014, 23:20
Tài liệu The Economic and Social Effects of Financial Liberalization: A Primer for Developing Countries pptx
... đầutư không muốnmuachứng khoán xấu, như vậythị trườn g khôn g vân hành tốt g g Giải thích Puzzle 2 and Puzzle 1. Cũng giải thích Puzzle 6: Càng ít thông tin bấtcânxứng cho những công ty hoạt động tốt thì vấn đề hiện tượng trái chanh càng nhỏ hơn Copyright ... chính (Q uản tr ị tài chính ) – Trong đo ù : (Q ị ) Trong ño: EBIT (Earnings before interest and taxes) T : Ta es T : Ta x es EBIT x (1- T)= Lợi nhuận sau thuế đối với nợ ø á å hà va ø vo á nco å p h a à n. ...
Ngày tải lên: 20/01/2014, 19:20
Tài liệu Positive and Negative Spaces doc
... shapes of positive and negative spaces allows you to find and subsequently draw an outline of any drawing subject. Positive space is the space in a drawing that is occupied by an object and/ or ... of the negative space to the left of the egg-shape (A) is slightly wider than the negative space on the right (B). The width of the negative space to the right (B) is equal to the height of ... distances, and apply the resulting information to your drawings. This article illustrates and demonstrates the process of breaking down subjects into positive and negative spaces, and sketching...
Ngày tải lên: 21/01/2014, 08:20
Tài liệu NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Di-Isodecyl Phthalate (DIDP) pdf
... pregnancy and gestation. Complete details of the study, including a description of reproductive effects in parents and offspring, are included in Section 4. In the F 1 offspring there were no effects ... reduced on pnd 1 and 4 in all treated groups, and also on pnd 7 and at weaning in the high-dose group. An unusually high incidence of pup deaths in 4, 2, and 4 litters of the low-, mid-, and high- dose ... rates and body weights reported by authors, doses of 0, 15, 77, and 307 mg/kg bw/day and 0, 16, 88, and 320 mg/kg bw/day were calculated for males and females, respectively. There were no effects...
Ngày tải lên: 13/02/2014, 10:20
Tài liệu A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco pptx
... its peculiar effects. End of the Project Gutenberg EBook of A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco, by A. McAllister *** END OF THIS PROJECT ... variety of computers including obsolete, old, middle-aged and new computers. It exists because of the efforts of hundreds of volunteers and donations from people in all walks of life. Volunteers and ... Gutenberg EBook of A Dissertation on the Medical Properties and Injurious Effects of the Habitual Use of Tobacco, by A. McAllister This eBook is for the use of anyone anywhere at no cost and with almost...
Ngày tải lên: 17/02/2014, 22:20
NTP-CERHR MONOGRAPH ON THE POTENTIAL HUMAN REPRODUCTIVE AND DEVELOPMENTAl EFFECTS OF BISPHENOL A pot
... than the developmental effects observed at “high” doses on survival and growth and the “low” dose effects on brain and behavior, mammary gland, prostate gland, and onset of puberty in females ... these findings and include longer periods of follow-up to understand the significance of the structural and cellular effects observed in fetuses and to clarify the relevance of prostate intraepithelial ... effects Some evidence of adverse effects Limited evidence of adverse effects Developmental and reproductive toxicity Insufcient evidence for a conclusion Limited evidence of no adverse effects Some...
Ngày tải lên: 05/03/2014, 16:20
Báo cáo khoa học: Alternative splicing: good and bad effects of translationally silent substitutions pdf
... splicing. A variety of tools are available to us for this purpose and further investigation of these sequence variants will not only further our understanding of the splicing mechanism and improve clinical ... (mouse–rat and human–dog) [10]. This analysis showed a strong puri- fying selection at silent sites in a critical region of this gene [10], spanning the 3Â end of exon 10 and the 5Â end of exon ... the detection of both lower K a and K s in one region is probably an index of splicing constraint rather than the detection of K a ⁄ K s peaks, which may be due to a high K a ratio and not to selec- tive...
Ngày tải lên: 06/03/2014, 09:22
Báo cáo khoa học: Structural and biological effects of a b2- or b3-amino acid insertion in a peptide Application to molecular recognition of substance P by the neurokinin-1 receptor ppt
... L., Hommel,U.&Widmer,H.(1998)b 2 -andb 3 -peptides with proteinaceous side chains. Synthesis and solution structures of constitutional isomers, a novel helical secondary structure, and the influence of solvation and hydrophobic ... presence of helical structures was con- firmed by the observation of NN (i, i +1),aN(i, i +2),aN (i, i +3),aN(i, i +4)andab (i, i + 3) NOEs along the 5–8 domain of SP and [Aib 9 ]SP. The aN(i, i +4) and ... shifts and random coil values, are commonly used to detect secondary structures in peptides and proteins [38]. TheyarereportedinFig.3. Stronger upfield shifts of H a (Fig. 3A) and downfield shifts of...
Ngày tải lên: 08/03/2014, 08:20
The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and the Effects of Care on Client Mobility: Findings from Contra Costa, California pdf
... Transportation Efficiency Act of 1991 ii Abstract The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and the Effects of Care on Client Mobility: ... (TAZ) and zip code. Note. Based on Metropolitan Transportation Commission (MTC) data i The Effects of Land Use on the Mobility of Elderly and Disabled and Their Homecare Workers, and ... habits and needs of consumers and providers, and the extent of care consumers received. The six interrelated hypotheses predicted that, given the income constraints of both populations and the...
Ngày tải lên: 14/03/2014, 17:20
industry and the effects of climate in italy
... 200 m; off the coast of Puglia, however, it exceeds a depth of 1,200 m. Finally, in the area of the Strait of Otranto the two shores of the Adriatic draw close together and here the Italian and ... depositing at the feet of the chains of huge deposits of sand, gravel and clay. There then followed a phase of general increased marine predominance, lasting a good part of the Miocene and all the Pliocene. ... winter, and the summers are hot and dry. The interior and mountain zones of the islands and Calabria also have an Apennine type climate due to the altitude. Inland WatersThe characteristics of the...
Ngày tải lên: 21/03/2014, 22:04
Sputum cellularity in pulmonary tuberculosis: A comparative study between HIV-positive and -negative individuals pptx
... of cases (10 HIV -positive and 19 HIV -negative) , alveolar injury in 32 (80%) of cases (13 HIV -positive and 19 -negative) , interstitial lesion in 15 (37.5%) of cases (8 HIV -positive and 7 -negative) , ... 10 (25%) of cases (4 HIV- positive and 6 -negative) , pleural effusion in 9 (22, 5%) of cases (3 HIV -positive and 6 -negative) , atelectasis in 4 (10%) of cases (1 HIV -positive and 3 -negative) , ... 22 to 69 years. Of the participants, 16 (40%) were HIV positive and 24 (60%) were negative. Mean age of HIV -positive individuals was 35.9 years (SD±7.16) and mean age of HIV -negative individuals...
Ngày tải lên: 22/03/2014, 18:20
Báo cáo khoa học: A distinct sequence in the adenine nucleotide translocase from Artemia franciscana embryos is associated with insensitivity to bongkrekate and atypical effects of adenine nucleotides on Ca2+ uptake and sequestration pdf
... rotein sequence with that of other species (Xenopus, Drosophila, mouse isoforms 1, 2, and 4, rat isoforms 1 and 2, bovine isoforms 1, 2, 3, and 4, and human isoforms 1, 2, 3, and 4) is shown in Fig. ... applies to Artemia mitochondria, we tested the effect of ADP and ATP in the presence and absence of the ANT inhibitory ligand cATR, and of the F 0 F 1 - ATP synthase inhibitor oligomycin. The ... inhibitors of ANT have also been reported [37]. Mindful of (a) the well-established ligand profile of ANT, (b) the modulatory role of ANT in the mam- malian PTP, and (c) the absence of a Ca 2+ -induced PTP...
Ngày tải lên: 29/03/2014, 00:20
Báo cáo khoa học: Prohibitin is expressed in pancreatic b-cells and protects against oxidative and proapoptotic effects of ethanol pdf
... b-cells. The objective of the present study was to investigate the expression and antioxidant effects of PHB in pancreatic b-cells exposed to ethanol. Results Effects of ethanol and recombinant PHB ... pancreatic b-cells and protects against oxidative and proapoptotic effects of ethanol Jong Han Lee 1 , K. Hoa Nguyen 1 , Suresh Mishra 1,2 and B. L. Gre ´ goire Nyomba 1,2 1 Department of Physiology, ... have health benefits [1]. The diabetogenic effects of ethanol may include its contribution to excess caloric intake and obesity, induction of pancreatitis and impairment of liver function [2]. Recent studies...
Ngày tải lên: 29/03/2014, 08:20