polysialic acid bioengineering of cancer and neuronal cells by n acyl sialic acid precursor treatment
Báo cáo khoa học: Differential regulation of fatty acid amide hydrolase promoter in human immune cells and neuronal cells by leptin and progesterone pdf
Ngày tải lên :
30/03/2014, 15:20
... differential regulation of FAAH gene expression in immune and neuronal cells, suggesting cell-specific links between networks controlled by leptin or progesterone and the peripheral endocannabinoid ... FAAH activity and expression (A) Effect of leptin on the activity of FAAH in human U937 and CHP100 cells and on the protein content and the mRNA of FAAH in U937 cells These cells were incubated for ... activity and protein content The effect of leptin and progesterone on FAAH activity and expression was additive, in fact treatment of U937 cells for 24 h with 10 nM leptin and lM progesterone enhanced...
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Tài liệu Báo cáo khoa học: Efficient killing of SW480 colon carcinoma cells by a signal transducer and activator of transcription (STAT) 3 hairpin decoy oligodeoxynucleotide – interference with interferon-c-STAT1-mediated killing pdf
Ngày tải lên :
18/02/2014, 08:20
... control ODN (con) and the dead cells were counted after 16, 24 and 48 h of culture using trypan blue staining (C) Cells were treated with 0.5, and lg of hpST3dODN and and lg of control ODN for h ... indicate a correlation between inhibition of STAT3 by hpST3dODN and induction of cell death In addition, they confirm previous observations made in head and neck nonsquamous carcinoma cell lines, ... the functions of STAT1 and STAT3 differ considerably and this must depend at some point on the specific recognition of a DNA-binding motif Specific inhibition of STAT3 by DNA-binding targeting may...
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Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf
Ngày tải lên :
19/02/2014, 16:20
... cyclin D1 gene promoter We studied the mechanism(s) underlying the inhibition of cyclin D1 gene expression by EPA and DHA by examining the effects of n- 3 and n- 6 PUFAs incorporation on cyclin D1 promoter ... obtained with 200 nM wortmannin, another PI3-K inhibitor (data not shown) We confirmed the implication of PI3-K in this signalling pathway by using a dominant-negative mutant of the p85 subunit of ... activation induced by AA, and the differing effects of n- 6 and n- 3 PUFAs on Egr-1 mRNA accumulation are consistent with their action upon the activation of cyclin D1 transcription accumulation [13]...
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Báo cáo sinh học: "Use of recombinant lentivirus pseudotyped with vesicular stomatitis virus glycoprotein G for efficient generation of human anti-cancer chimeric T cells by transduction of human peripheral blood lymphocytes in vitro" pot
Ngày tải lên :
19/06/2014, 08:20
... chemically induced tumors induce profound immunosuppression concomitant with apoptosis and alterations in signal transduction in T cells and NK cells Cancer Res 1999, 59:2950-2956 Friberg M, Jennings ... MHC/peptide and the TCR and a second, co-stimulatory signal, transmitted by interaction between CD28 on the lymphocyte and CD80 (B7-1)/86 (B7-2), generally present on professional antigen presenting cells ... Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma Int J Cancer 1997, 71:142-147 Cabrera T, Collado A, Fernandez...
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báo cáo hóa học:" Use of recombinant lentivirus pseudotyped with vesicular stomatitis virus glycoprotein G for efficient generation of human anti-cancer chimeric T cells by transduction of human peripheral blood lymphocytes in vitro" docx
Ngày tải lên :
20/06/2014, 04:20
... chemically induced tumors induce profound immunosuppression concomitant with apoptosis and alterations in signal transduction in T cells and NK cells Cancer Res 1999, 59:2950-2956 Friberg M, Jennings ... MHC/peptide and the TCR and a second, co-stimulatory signal, transmitted by interaction between CD28 on the lymphocyte and CD80 (B7-1)/86 (B7-2), generally present on professional antigen presenting cells ... Immunoselection in vivo: independent loss of MHC class I and melanocyte differentiation antigen expression in metastatic melanoma Int J Cancer 1997, 71:142-147 Cabrera T, Collado A, Fernandez...
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Báo cáo sinh học: "High-resolution quantitative imaging of mammalian and bacterial cells using stable isotope mass spectrometry" docx
Ngày tải lên :
06/08/2014, 18:21
... possibility of determining the generation of single cells from the amount of label within the cell, and the possibility of labeling both donor and recipient cells differently, enabling the unambiguous ... consequence, the brightness of an image area depends upon the local concentration of the element under consideration, the implanted Cs+ concentration and the sputtering rate Without any contrast, ... Journal of Biology 2006, Volume 5, Article 20 Lechene et al http://jbiol.com/content/5/6/20 DNA and RNA co-distribution and uridine incorporation in the nucleolus using 1 5N- uridine and 81Br of...
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Báo cáo sinh học: " Infectious causes of cancer and their detection" doc
Ngày tải lên :
06/08/2014, 19:21
... existence of new and emerging infections [6], make detection and proving causality challenging An infectious agent may trigger the initial events of oncogenesis but be absent in the final tumor, ... compromised immune system can result in an increased incidence of infection-driven tumors by weakening the immune control Such an increase is seen, for example, in transplant http://jbiol.com/content/8/7/67 ... Chronic inflammation • Production of inflammatory cytokines, ROS and RNOS • Increased cell cycling and proliferation • DNA, protein and membrane damage • Gene expression changes Figure Infectious...
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Báo cáo y học: "Hypertrophy is induced during the in vitro chondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein-2 and bone morphogenetic protein-4 gene transfer" pps
Ngày tải lên :
09/08/2014, 14:22
... hematopoietic and neuronal cells [42] Interestingly, in conditional knock-out experiments it has been found that a threshold level of BMP signaling is required for the onset of chondrogenesis, and hence ... BMP-4 and BMP-2 expression on chondrogenesis of primary MSCs and to investigate whether levels and extent of hypertrophy in vitro is influenced by the choice of transgene Materials and methods Construction ... alignment of the chondrocytes along the arcades of Benninghoff [29] and by the appearance of hypertrophic cells Analyses of lacunae surface areas in the different growth plate zones revealed mean...
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báo cáo khoa học: "More expressions of BDNF and TrkB in multiple hepatocellular carcinoma and anti-BDNF or K252a induced apoptosis, supressed invasion of HepG2 and HCCLM3 cells" docx
Ngày tải lên :
10/08/2014, 10:21
... an important role of BDNF/TrkB in regulating survival and invasion of HCC cells and probably provided new insight into the inhibition of BDNF/TrkB signaling as a target of anti-HCC therapies Nevertheless, ... on cell invasion To understand the potential signaling induced by BDNF/TrkB that affects cell invasion, anti-BDNF or K252a was used and the invasion of treated cells was examined by Transwell assay ... present study, the expressions of BDNF and TrkB in HCC specimens were examined, and by neutralizing BDNF or inhibiting TrkB kinase activity in HCC cell lines to observe the effects of BDNF/TrkB interruption...
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Báo cáo y học: " Dysregulated balance of Th17 and Th1 cells in systemic lupus erythematosus" doc
Ngày tải lên :
12/08/2014, 12:20
... phenotype, because IL-17 acts in conjunction with B-cell activating factor (BAFF) in promoting the survival and proliferation of human B cells and their differentiation into antibody-producing cells ... remains unknown why IL-17 production is increased in lupus and whether such a finding is related to Th1 cells producing IFN-g Determining the balance of Th17- and Th1-cell responses is important, ... including CD4 + , CD8 + T cells and innate immune cells, including macrophages and NK cells Thus, these assays could not tell whether such findings were secondary to increased IFN-g production...
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Báo cáo y học: " A multiscale mathematical model of cancer, and its use in analyzing irradiation therapies" ppt
Ngày tải lên :
13/08/2014, 23:20
... proliferation and in turn slows the evolution of the quiescent cell population These oscillations in cell population are caused by a combination of overpopulation signal propagation in the inner parts of ... number of cells (continuous line) and number of quiescent cells (dotted line) SMAD/RAS-dependent growth regulation Figure shows the time courses of total cell number and quiescent cell number In this ... signals, i.e hypoxia and overpopulation, activation thresholds above which cells go into quiescence (Tho and Tht); • initial conditions, i.e initial number of cells and spatial configurations of...
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a discourse analysis of opening and closing speeches by masters of ceremonyon reality television showsin american english versus vietnames
Ngày tải lên :
26/11/2013, 12:41
... clarification and having no pressure in terms of monitoring and processing communication spontaneously In summary, spoken language has certain features that are generally not shared by written one However, ... division of language into the spoken and the written is clearly and sensibly based on a difference in production and reception However, when the structure of discourse is taken into consideration, ... Linguistic Features of Antithesis in Political Speeches in English and Vietnamese (2008) by Van, An Investigation into Syntactic and Pragmatic Features of Parallelism in English and Vietnamese Political...
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USE OF HEALTH AND NURSING CARE BY THE ELDERLY pptx
Ngày tải lên :
05/03/2014, 18:20
... elderly and nursing homes persons receiving social pensions in nursing homes Finland nursing homes France "at the moment, you " Germany Netherlands recipients of long-term care insurance schemes nursing ... are concentrated in hospitals In Finland, Belgium and Spain most of the specialist work is in hospital outpatient departments and in Spain and Finland patients need a referral from a general ... variables have significant influence on the number of hospital days per inhabitant in 2001, in the case of hospital days per inpatient gender and education have no significant influence in 2001 if the...
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Báo cáo khoa học: A new molecular tool for transgenic diatoms Control of mRNA and protein biosynthesis by an inducible promoter–terminator cassette docx
Ngày tải lên :
07/03/2014, 21:20
... in the presence of nitrate and under conditions of nitrogen starvation, but not in ammonium-containing medium Ammonium proved to be an inhibitor of CfNR expression, as shown by the lack of CfNR ... present unknown if nitrogen-starved FEBS Journal 272 (2005) 3413–3423 ª 2005 FEBS N Poulsen and N Kroger ¨ cells synthesize AMT and NAT protein or if translation of AMT and NAT mRNAs is inhibited, ... transgenic diatoms A B Fig Influence of nitrogen source on mRNA expression and the formation of GFP protein (A) Fluorescence images of C fusiformis Clone 31 cells in nitrogen-free medium ( N) and...
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University musical encyclopedia the theory of music and piano technique (by e markham) (1912)
Ngày tải lên :
15/03/2014, 13:44
... Reciting note (d) I -]th I I Inflections and cadence Tone, ^th ending Intonation Mediation [_J Reciting note Inflections | and cadence | ] > J F/U
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Outlines of Greek and Roman Medicine, by James Sands Elliott This eBook is for the use of anyone anywhere at no cost and with almost no restrictions whatsoever. You may copy it, give it away or re-use it under the terms of docx
Ngày tải lên :
15/03/2014, 15:20
... Ephesus Marinus Quintus CHAPTER IX Galen His life and works His influence on Medicine CHAPTER X The Later Roman and Byzantine Period Beginning of Decline Neoplatonism Antyllus Oribasius Magnus Jacobus ... courtesy and attention James Sands Elliott Wellington, New Zealand January 5, 1914 CONTENTS PREFACE CONTENTS ILLUSTRATIONS CHAPTER I Early Roman Medicine Origin of Healing Temples Lectisternium ... way in Rome, and among the Egyptians, the Jews, the Chaldeans, Hindus and Parsees, and the Chinese and Tartars The Etruscans had considerable proficiency in philosophy and medicine, and to this...
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Báo cáo khoa học: Repeats of LacdiNAc and fucosylated LacdiNAc on N-glycans of the human parasite Schistosoma mansoni doc
Ngày tải lên :
16/03/2014, 14:20
... core-(a1–6)-fucosylation, LDNF-LDN antenna, LDN-LDN- antenna, LDNF- antenna core-(a1–6)-fucosylation, partially fucosylated LDN-LDN- antennae, LDN(F)- antenna no core-fucosylation, LDNF-LDNF- antennae, LDNF- antenna ... antenna, LDNF- antenna LDN-LDN- antenna, LDN- antenna, antenna of a single HexNAc residue (truncated) core-(a1–6)- fucosylation, LDNF-LDN- antenna, antenna of a single HexNAc residue (truncated) ... LDN- antenna, LDN- antenna LDN-LDN- antenna, LDN- antenna, both possibly fucosylated core-(a1–6)- fucosylation, LDNF- LDNF- antenna, LDN- antenna core-(a1–6)- fucosylation, LDNF- LDNF- antenna,...
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Báo cáo khoa học: Gain of structure and IgE epitopes by eukaryotic expression of the major Timothy grass pollen allergen, Phl p 1 pdf
Ngày tải lên :
16/03/2014, 18:20
... UDPglucosyltransferase signal peptide [39] for enhanced secretion of the recombinant protein into the culture supernatant and a C-terminal His6-tag The pBacPAK8 construct was confirmed by DNA sequencing and ... amplification Expression and purification of rPhl p from baculovirus-infected insect cells The expression of rPhl p in insect cells was optimized by infecting Sf9 cells with different amounts of virus and ... degranulation was tested by incubation of granulocytes with various concentrations of the purified proteins and by measuring histamine released into the cell-free supernatant by radioimmunoassay...
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Kemetic Roots of Library and Information Science, By Itibari M. Zulu docx
Ngày tải lên :
28/03/2014, 18:20
... "the black land", Egypt, the home of all humankind, a high culture, and the African world community, and consequently, an essential starting point in any discussion of civilization and history ... Decimal, and the Ranganathan Colon systems by thousands of years Kemetic Roots of Library and Information Science, by Itibari M Zulu Page 15 of 27 Classification The putting of like kinds of works in ... thus institutionalized in the office of the vizier, the chief administrator and official of the government, who catalogued and inventoried " every Egyptian," and all things in Egypt, and headed...
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