poly ethylene glycol conjugates of filgrastim
Báo cáo y học: "Control of hyperuricemia in subjects with refractory gout, and induction of antibody against poly(ethylene glycol) (PEG), in a phase I trial of subcutaneous PEGylated urate oxidase" potx
Ngày tải lên :
09/08/2014, 07:20
... monomethoxy polyethylene glycol modified proteins Int Arch Allergy Appl Immunol 1983, 70:124-131 32 Cheng TL, Wu PY, Wu MF, Chern JW, Roffler SR: Accelerated clearance of polyethylene glycol- modified ... Effect of attachment of polyethylene glycol on immunogenicity and circulating life of bovine liver catalase J Biol Chem 1977, 252:3582-3586 Veronese FM, Harris JM: Introduction and overview of peptide ... Characterization of suppressor T cell clones derived from a mouse tolerized with conjugates of ovalbumin and monomethoxypolyethylene glycol Cell Immunol 1992, 142:16-27 36 Lee WY, Sehon AH: Suppression of...
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báo cáo khoa học: "Formulation of polylactide-co-glycolic acid nanospheres for encapsulation and sustained release of poly(ethylene imine)-poly(ethylene glycol) copolymers complexed to oligonucleotides" pptx
Ngày tải lên :
11/08/2014, 00:22
... Comparisonof mdx numberthe dystrophin-positivekDa) nanoFigure encapsulated with of PEG-PEI-AO polyplex spheres injections of of the mice polyplex and PLGA (17 fibers in Comparison of the number of dystrophin-positive ... and the negatively-charged elements of cell membranes, promoting endocytotic uptake of the nucleotides into cells [10-17] Grafting of polyethylene glycol (PEG) polymers to PEI has been shown to ... PEG-PEI copolymers Details of the synthesis of the PEG-PEI copolymers, as well their physicochemical properties when complexed with AO were previously described [47] Briefly, copolymers composed of...
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Báo cáo khoa hoc:" Evaluation of triblock copolymeric micelles of δvalerolactone and poly (ethylene glycol) as a competent vector for doxorubicin delivery against cancer" doc
Ngày tải lên :
11/08/2014, 08:20
... diagram of synthesis of Poly( δ-valerolactone) /Poly( ethylene glycol) /Poly (δ-valerolactone) (VEV) copolymer using δ-valerolactone and poly( ethylene glycol) as monomers by ring opening polymerization ... involves the synthesis of a triblock copolymer of δ- Page of 14 valerolactone, poly δ-valerolactone) /poly( ethylene glycol) /poly( δ-valerolactone) (VEV) by ring opening polymerization and characterization ... δ-Valerolactone (VL) (B) Poly (ethylene glycol) (PEG) and the synthesized copolymer VEV (C) Poly (δ-valerolactone) /Poly( ethylene glycol) /Poly( δ-valerolactone) (VEV) copolymer were recorded using...
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Evaluation of poly (ethylene glycol) grafting as a tool for improving membrane performance
Ngày tải lên :
05/07/2016, 14:26
... Moleculae Weight Cutoff Nanofiltration Natural Organic Matter N-Vinyl -2 - Pyrrolidone Polyamide Polyacrylonitrile Polyethylene Polyethylene glycol Polyethylene oxide Polyether sulfone Polyethylene terepthalate ... Enhancer: Poly (Ethylene Glycol) Poly (ethylene glycol) -lipid (PEG-lipid) conjugates are widely used in the field of nanoparticulate drug delivery They are used to provide a protective cloud of polymer ... hydrophobic polymers such as polypropylene (PP) and polyethylene (PE) Various polymers with intermediate hydrophilicity such as polysulfone (PS) / polyether sulfone (PES) family, polyacrylonitrile...
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Báo cáo y học: " Novel multi-component nanopharmaceuticals derived from poly(ethylene) glycol, retro-inverso-Tat nonapeptide and saquinavir demonstrate combined anti-HIV effect" potx
Ngày tải lên :
10/08/2014, 05:20
... evaluation of polyethylene glycol esters of hydrocortisone 21-succinate as ocular prodrugs Int J Pharm 1999, 182:79-92 Caliceti P, Veronese FM: Pharmacokinetic and biodistribution properties of poly( ethylene ... formation of the bioconjugates (8–11) was confirmed by MALDI-TOF mass spectrometry and the concentrations of bioconjugates were determined by amino acid analysis In the synthesis of the SQV conjugates ... inhibition by the conjugates These bioconjugates were designed (i) to carry multiple copies of the R.I.CK-Tat9 drug linked by stable thioether bonds to 8-arm poly( ethylene) glycol (PEG), (ii)...
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Synthetic poly(ethylene glycol) based hydrogels for biomedical applications
Ngày tải lên :
08/09/2015, 19:48
... enantiomeric pure polylactide segments in the micelle cores (e) Scheme A.1 Synthetic schemes of VS-PEG-polycarbonate Scheme C.1 Typical synthesis of polylactide-b -poly( ethylene glycol) -b-polylactide ... P(D,L)LA Poly( D, L-lactide) PDLA-CPC-PDLA Poly( D-lactide)-charged polycarbonate- poly( D-lactide) PEC Polyelectrolyte complex PEG Poly( ethylene glycol) PEG-AC Tetra acrylate-terminated PEG PEGDA Polyethelyne ... synthetic polymers, such as poly (D,L-lactic-co-glycolic acid) (PLGA) [15], poly (hydroxyethyl methacrylate (pHEMA) [16] and poly (ethylene glycol) (PEG) [17, 18], have been used in the formulation of...
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effect of water content of ethylene glycol as electrolyte for synthesis
Ngày tải lên :
19/03/2014, 16:48
... oxidation of ethylene glycol in acidic and basic media has been investigated widely [24– 26] In the aqueous solution, the oxidation of ethylene glycol involves the following reaction steps: [25] Ethylene ... of production of glycolic acid during the oxidation of ethylene glycol (with 0.1 M HClO4 supporting electrolyte) at 0.3 V vs SCE The increase in the anodic current above 0.8 VPt in the case of ... and water contents Addition of 0.2 M of 48% HF acted as a source of water As the nanotubes formation was not uniform in the
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Báo cáo khoa học: "Effect of ethylene glycol monoethyl ether on the spermatogenesis in pubertal and adult rats" pdf
Ngày tải lên :
07/08/2014, 14:23
... the control Effects of EGEE on the spermatogenesis of different age of male rats 49 Fig Epididymis weight of pubertal (a) and adult (b) rats administered with various doses of EGEE for weeks Weights ... weights of testes and epididymis were normalized by 100 g of body weight The administration of EGEE at the doses of 50, 100, 200, and 400 mg/kg increased significantly (p
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Ethylene glycol
Ngày tải lên :
17/03/2014, 09:09
... Một số tính chất vật lí của ethylene glycol và dẫn xuất: Tên chất Diethylene glycol Trietylen glycol Tetraethylene glycol Công thức Monoethylene glycol HOCH2CH2OH H(OCH2CH2 ) 2OH H(OCH2CH2 ) 3OH H(OCH2CH2 ... dùng công nghiệp e Phản ứng epoxy hóa Ethylene glycol phản ứng với ethylene oxit để tạo thành di , tri , tetra , và polyethylen glycol. Tỷ lệ của các glycol tìm thấy trong các sản phẩm phản ứng phụ thuộc vào loại xúc tác được xử dụng ... alkyl: trình este hóa glycol với polyhydrit axit tạo sản phẩm polyeste, sau biến đổi để làm nguyên liệu cho ngành sơn; Các loại nhựa polyeste (dạng sợi, màng polyeste, nhựa polyetylen terephtalat)...
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ethylene glycol assisted hydrothermal synthesis offlower like zno architectures
Ngày tải lên :
06/05/2014, 13:23
... diagram of flower like ZnO architecture prepared (a) absence of ethylene glycol and (b) presence of ethylene glycol Fig Raman spectrum of ZnO crystals Fig Room temperature PL spectrum of ZnO crystals ... the quantity of ethylene glycol is reduced to less than 20 ml On the other hand, the morphology of the ZnO is changed to hexagonal rods (Fig 2e and f) when the quantity of ethylene glycol is reduced ... of polyhedral crystals [25] The two polyhedral crystals are joined each other by the action of ethylene glycol, forms twinned crystals Similar observation was made by Zang et al in presence of...
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NGỘ ĐỘC ALCOOLS : ETHYLENE GLYCOL, METHANOL VÀ ISOPROPYL ALCOHOL pps
Ngày tải lên :
26/07/2014, 19:20
... METHANOL VÀ ETHYLENE GLYCOL TƯƠNG TỰ NHAU NHƯ THẾ NÀO ? Methanol ethylene glycol khởi đầu chuyển hóa ADH Methanol tiếp tục chuyển hóa thành formic acid, ethylene glycol chuyển hóa thành glycolic ... xét đến ngộ độc alcohol, methanol hay ethylene glycol Nếu có osmolal gap bất thường anion gap, xét đến ngộ độc isopropyl alcohol 10/ METHANOL VÀ ETHYLENE GLYCOL ĐỘC NHƯ THẾ NÀO ? Tử vong ghi nhận ... Chúng nên sử dụng nồng độ ethylene glycol hay methanol vượt 20 mg/dL ; có nhiễm toan nồng độ ; có bệnh sử uống chất độc chờ đợi nồng độ xác nhận methanol hay ethylene glycol 19/ ĐIỀU TRỊ ETHANOL...
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Báo cáo toán học: "Bordered Conjugates of Words over Large Alphabets" pot
Ngày tải lên :
07/08/2014, 15:22
... characterize the set of the images β(w) for w ∈ B ∗ The words xy and yx are called conjugates of each other We denote by [w] the set of all conjugates of the word w Note that if u and v are conjugates ... conjugate of w that starts and ends in a different letter is unbordered and all other conjugates are, of course, bordered by a border of length one Hence, we have β(w ) = u which completes the proof ... s, t > This concludes the proof We now show that almost all binary words of length n are β-images Proof of the main Theorem Let u ∈ {a, b}∗ be a nonempty binary word of length n We proceed by a...
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Xác định hàm lượng Diethylene Glycol, Ethylene Glycol có trong kem đánh răng bằng phương pháp GC-MS potx
Ngày tải lên :
08/08/2014, 06:21
... 1,2-propanediol, 1,3-propanediol, diethylene glycol hay glycerin 1,2-Propanediol Start Time a (min) 4.0 Ethylene Glycol 6.6 1,3-Propanediol 7.5 Diethylene Glycol 9.0 Glycerin 12.0 Group 31 (11) ... giàu gồm có đại diện cho loại mẫu phân tích va làm giàu thêm chất phân tích (tức Diethylene glycol ethylene glycol) mức mg/g (hoặc 0.1 % trọng lượng) Phép phân tích mẫu phải thể chất có diện ... tử b - Sự nhận peak: Thời gian lưu gần phép phân tích: Chất 1,2-Propanediol Ethylene Glycol 1,3-Propanediol Diethylene Glycol Glycerin Thời gian lưu (min) 6.4 6.8 8.4 10.4 13.7 Chú giải Đây chất...
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báo cáo khoa học: " Nucleoside conjugates of quantum dots for characterization of G protein-coupled receptors: strategies for immobilizing A2A adenosine receptor agonists" pdf
Ngày tải lên :
11/08/2014, 00:22
... approaches to the derivatization of CdSe/ZnS QDs to achieve conjugation of active agonists of the A2AAR The problems of limited aqueous solubility of the QD [20-23] and access of the flexible tethered ... Pharmacological Characterization of Nucleoside Conjugates of QDs The affinity of the QD conjugates was examined in a standard radioligand binding assay using [3H]1a in membranes of human embryonic kidney ... nucleoside conjugates and their underivatized precursor QDs are shown in Table (2 13) Structures of these derivatives are shown schematically in Additional file 1, Table S1 Synthesis of QD Conjugates of...
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Báo cáo y học: "Delayed ethylene glycol poisoning presenting with abdominal pain and multiple cranial and peripheral neuropathies: a case report" ppt
Ngày tải lên :
11/08/2014, 03:20
... level of 131 mmol/L, potassium level of 6.7 mmol/L, urea of 45.2 mmol/L, and creatinine of 1885 micromol/L (21.3 mg/ dL) Of note were a raised C-reactive protein of 421, neutrophil count of 25.9 ... sedimentation rate of 100 Blood gases revealed a pH of 7.19, a PO2 of 14.8 kPa, pCO2 of 5.18 kPa, HCO3 of 14.5 mmol/ L with a base deficit of -12.9 on 28% inspired oxygen, and an anion gap of 28 mmol/l ... findings of immediate versus delayed presentation W V Med J 2006, 102:32-34 Hess R, Bartels MJ, Pottenger LH: Ethylene glycol: an estimate of tolerable levels of exposure based on a review of animal...
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Structural basis of protein stability at poly extreme crystal structure of amya at 1 6 a resolution
Ngày tải lên :
16/09/2015, 08:31
... the addition of a lattice point in the center of each of the six faces of each unit-cell), body centered (point at the center of the cell) and end centered (point at the center of one face) The ... bodies and wavelengths of incident radiation In Bragg’s model of diffraction as reflection from parallel sets of planes, (Fig 1.1) any of these sets of planes can be the source of one diffracted X-ray ... expansion of a periodic function f(x) in terms of an infinite sum of sines and cosines and makes use of the orthogonality relationships of the sine and cosine functions The computation and study of...
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Structural basis of protein stability at poly extreme crystal structure of amya at 1 6 a resolution 3
Ngày tải lên :
16/09/2015, 08:31
... possible to measure an S-value distribution of the sample which indicated that 70% of the protein was sedimenting with an S-value of around 85-90 S, about 25% of the protein sedimenting 64 between ... Dalton with the majority of the sample around million Dalton Figure 3.4 Molecular weight distribution of AmyA at no salt The peak corresponds to a poly- dispersed aggregate of AmyA However, these ... aggregate of AmyA However, these aggregates retain 40% of activity when tested (Fig 3.2) Addition of as low as mM of NaCl reversed most of the protein aggregates into the monomeric form, sedimenting...
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Structural basis of protein stability at poly extreme crystal structure of amya at 1 6 a resolution 4
Ngày tải lên :
16/09/2015, 08:31
... capacity of AmyA does not get affected in high salt solution despite the lack of excess acidic residues A B Figure 4.12 Overview of the solvation sphere of AmyA (A) lAmyA and (B) hAmyA The surfaces of ... protein surface and the core of AmyA might contribute collectively and significantly to the thermal stability of AmyA 86 Table 4.8 The number of ion pair networks of AmyA and other homologous ... the chloride ion of hAmyA is represented as a cyan sphere Figure 4.4 Active site comparisons A stereo view of the active site cleft and comparison of the key catalytic residues of lAmyA (green)...
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