... synthesized in five steps from D -pantothenate. The Dfp flavoprotein catalyzes the synthe- sis of the coenzyme A precursor 4 -phosphopantetheine from 4 -phosphopantothenate and cysteine using the ... residue [5], it is tempting to speculate that the loop is involved in binding one of the (co)substrates of CoaB, indicating that the provided models of the substrate binding sites of human CoaB do not ... motif of the C-terminal CoaB domain is exchanged for Thr. Fig. 1. The role of Dfp (CoaBC) in 4 -phosphopantothenoylcysteine and 4 -phosphopantetheine biosynthesis. Coenzyme A is synthesized in ve...
Ngày tải lên: 19/02/2014, 12:20
Báo cáo khoa học: "Contents and evaluation of the first Slovenian-German online dictionary" doc
Ngày tải lên: 17/03/2014, 22:20
English Language Proficiency Tests-Advanced Level''''sarchiveAt the End of the Day (4) pdf
Ngày tải lên: 25/07/2014, 07:20
Báo cáo y học: "Expression of hMSH2 protein of the human DNA mismatch repair system in oral lichen planus"
... protein in basal and intermediate epithelial layers of normal oral mucosa (streptavidin-biotin amplified system, x 40 0). Int. J. Med. Sci. 20 04 1(3): 146 -151 146 International Journal of ... testicular germ cells [28], in the transitional epithelial cells of the bladder [20], and in the basal cell line of epidermis and oral mucosa [29]. Inactivation of hMSH2, one of the most commonly hMMR ... any staining of the nucleus, regardless of staining intensity. Cell counting was performed in six high-power microscopic fields (40 0x, Standard 20, ZEISS), which comprised almost all of the OLP...
Ngày tải lên: 03/11/2012, 09:54
Children security as part of the " living together with floods" strategy in the Mekong river delta, VietNam
... percentage of child deaths in the total the losses of life in the flood seasons in the MD. Save the Children (2003) reported that the vast majority of the drowning deaths in recent years in the region ... deaths of children from drowning. In peak flow periods, all children (over 160,000) in the high inundated areas are not attending their schools. The beginning and the end of the rainy season ... rice fields and flood plains. Some of them learn to swim at early age, but others were not trained. There is no official swimming training in the school program in the Mekong River Delta. It...
Ngày tải lên: 18/10/2013, 12:15
Tài liệu Báo cáo " Study on Monte-Carlo calculation of peak efficiencies of the superpure Hp Ge detector (Gmx) in environmental gamma spectrometry with using MCNP4C2 " pptx
... (2007) 9- 14 101 Fig.1. The confguration of the HP Ge (GMX) detector. Relating to the physical dimensions of the above detector the thickness of the dead layer lying at the back of the detector ... MCNP4C2 includes the following parts: - The sensitive volume of the detector - The mounting materials around detector - The entrance window or cover over the front of the detector - The ... until all of their energy has been dissipated in the various materials or escaped out of the physical space included in the model. For the interaction in the detector volume, MCNP4C2 produces...
Ngày tải lên: 13/02/2014, 04:20
Tài liệu THE STATE OF THE WORLD’S CHILDREN 2012: Children in an Urban World pptx
... examines some of the phenomena shaping the lives of children in urban areas, from their reasons for moving to the city and their experience of migration to the challenges of getting by in the ... mother-to- child transmission in 2010. 34 In addition, nearly 2,600 people aged 15– 24 were infected every day in 2010. These infections were mainly the result of unprotected sex or unsafe injec- tion ... obvious as in a city. Over the course of a decade, the state of the world’s urban children has worsened. The number of people living in slums has increased by over 60 million. These are mothers...
Ngày tải lên: 18/02/2014, 15:20
Tài liệu Báo cáo khoa học: Implication of the glutamine synthetase ⁄glutamate synthase pathway in conditioning the amino acid metabolism in bundle sheath and mesophyll cells of maize leaves doc
... cyto- plasmic layers of BSCs (Fig. 4A). No positive staining was detected in the BSCs using the control sense probe (Fig. 4B). The localization of GLU mRNAs in the vicinity of the vascular bundle of BSCs ... 33% in the light to 25% in the dark (Fig. 7A). Glutamine and asparagine were the major amino acids in the xylem sap in both the light (63% of the total amino acids) and dark (60%) (Fig. 7B). The ... the main nitrogen compounds in the phloem exudates, amounting to 51% of the total amino acids in the light and 56% in the dark (Fig. 7A). The total amount of alanine, serine and gly- cine was...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khóa học: Characterization of the products of the genes SNO1 and SNZ1 involved in pyridoxine synthesis in Saccharomyces cerevisiae pptx
... renaturation of either one or both of the proteins was incomplete and the complex formation is slow and/or incomplete under the conditions employed. Inhibition of the glutaminase activity by DON Glutamine ... of the genes. In SNO1, the 199th G from the 5Â terminus of the open reading frame was deleted to result in a frame-shift and appearance of stop codons in the downstream. As a result, a protein ... protein. FEBS Lett. 44 9, 45 48 . 4. Tazuya,K.,Adachi,Y.,Masuda,K.,Yamada,K.& Kumaoka, H. (1995) Origin of the nitrogen atom of pyridoxine in Saccharomyces cerevisiae. Biochim. Biophys. Acta 1 244 , 113–116. 5....
Ngày tải lên: 19/02/2014, 12:20
Tài liệu HIGHLIGHTS OF THE AUTHORISATION REQUIREMENTS FOR FUND DISTRIBUTION IN HONG KONG doc
... to the authorisation of the Securities and Futures Commission (the “SFC”) . 3 February 2012 PwC 3. Hong Kong Offering Document ã The Hong Kong Offering Document of a scheme should contain, inter ... contain, inter alia, the following information: Constitution of the scheme (e.g. the name, registered address, place and date of creation of the scheme, an indication of the scheme's duration ... VIII of the Trustee Ordinance (Chapter 29 of the laws of Hong Kong) and such company is an affiliate of an authorized financial institution defined under the SFO and is acceptable to the SFC....
Ngày tải lên: 19/02/2014, 14:20
Tài liệu Báo cáo khoa học: The Ets transcription factor ESE-1 mediates induction of the COX-2 gene by LPS in monocytes doc
... analysis in murine monocytic RAW 2 64. 7 cells. The intensity of the ECL signal was determined using the alphaease fc sofware and divided by the protein concentration of the sample. ESE-1 protein was ... cells leads to an induction of ESE-1 mRNA expression within 1 h of exposure, reaching a peak at 4 h and leveling off after 24 h [12]. To investigate the level of ESE-1 protein following LPS exposure, ... cooperates with ESE-1 in transactivating the iNOS promoter in endo- A B Fig. 3. ESE-1 binds to several Ets sites in the COX-2 promoter. (A) Interaction of ESE-1 with Ets binding sites in the COX-2 promoter....
Ngày tải lên: 19/02/2014, 17:20
Tài liệu Báo cáo Y học: Short peptides are not reliable models of thermodynamic and kinetic properties of the N-terminal metal binding site in serum albumin doc
... modelling of C u(II) and Ni(II) transport by albumins. On the other hand, the direct thermodynamic and kinetic characterization of Ni(II) binding at site I in HSA and BSA was obtained. These data ... by the protonation state of the lysine amine, which is not involved in coordination. For VIHN only the 4N species were detected, while potentio- metric titrations indicated the presence of minor ... he N-terminal peptide o f another blood serum protein, d es-angiotensino- gen [11]. The structure of the Ni(II) complex of the latter contains a specific steric shielding, resulting in a particularly slow...
Ngày tải lên: 22/02/2014, 04:20
An Account of the Diseases which were most frequent in the British military hospitals in Germany pptx
... not the Cause of the Fever; but being lodged in the Intestines, before the Fever comes on, they are annoyed by the Increase of the Heat, and the Corruption of the Humours, in the Cavity of the Intestines ... Intermitting Fever, or Ague, 179 Of the Jaundice, 206 Of Tumours of the Breast, 216 Of Paralytic Complaints, 219 Of an Incontinency of Urine, 223 Of a Stoppage of Urine, 227 Of the Epilepsy, 237 Of the ... frequent in the An Account of the Diseases which were most by Donald Monro 1 Of the Epidemical Catarrhal Fever of April 1762, 137 Of the Rheumatism, 141 Of the Autumnal Remitting Fever, 1 54 Of the Intermitting...
Ngày tải lên: 06/03/2014, 20:20
Báo cáo khoa học: Studies on the role of the receptor protein motifs possibly involved in electrostatic interactions on the dopamine D1 and D2 receptor oligomerization pdf
... from the ic3 of the D 2 R (217RRRRKR222) and either the two adjacent Asp residues (DD 40 1 40 2) or a phosphorylated Ser3 74 in the C-tail of the A 2A R [43 ]. Because the dopamine D 1 R contains ... modification of the Arg-rich region in the ic3 of the D 2 receptor substantially changed its receptor traf- ficking properties. The binding experiments also pointed to a decrease in the density of the ... co-expressed with the appropriate a sub- unit of the G protein and not in the other case. Although there is discussion in the literature concern- ing the possibilities of photoconversion of YFP into a CFP-like...
Ngày tải lên: 07/03/2014, 03:20
Báo cáo khoa học: Characterization of the NADH:ubiquinone oxidoreductase (complex I) in the trypanosomatid Phytomonas serpens (Kinetoplastida) ppt
... arrows). Owing to the horizontal smear, however, the presence of the B 14 subunit in the lower band cannot be ascer- tained at this point. A cross-reaction of the antibody against the 39 kDa subunit of ... in uences of DPI on the two forms could be caused by its failure to access the flavin cofactor in the large form of complex I, whereas the cofactor remains accessible in the small form. Indeed, to address ... Duve Institute of Cellular Pathol- ogy) for critical reading of the manuscript. This work was supported by grants from the Grant Agency of the Ministry of Education of the Slovak Republic and the...
Ngày tải lên: 07/03/2014, 09:20