phụ lục 2 mẫu nhiệm vụ và nhận xét đồ án
Báo cáo y học: "Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis" potx
... Rheum 20 05, 52: 229 3 -22 99 Maradit-Kremers H, Nicola PJ, Crowson CS, Ballman KV, Gabriel SE: Cardiovascular death in rheumatoid arthritis: a populationbased study Arthritis Rheum 20 05, 52: 722 -7 32 Sugaya ... Associations of Creactive protein with measures of obesity, insulin resistance, 17 18 19 20 21 22 23 24 25 26 and subclinical atherosclerosis in healthy, middle-aged women Arterioscler Thromb Vasc ... disease Smoking pack-year historya 17 (22 ) Current smoker, n (%) 52 (22 .9) History of hypertension, n (%) 78 (33.9) History of hyperlipidemia, n (%) 52 (22 .9) Use of statins in hyperlipidemia...
Ngày tải lên: 09/08/2014, 10:20
Báo cáo y học: "levels of soluble receptor for advanced glycation end products in patients with rheumatoid arthritis indicating deficient inflammatory control" docx
... Figure * 20 00 1600 * 1400 120 0 * 1000 800 600 400 20 0 Healthy RF + Erosive RF – Erosive RF + No eros RF – No eros 129 0 ±78 ( 122 7) 8 32 ±87 (771) 1105 20 9 (935) 5 82 ±141 (6 02) 945 ± 128 (7 72) itivity ... Arthritis Rheum 20 03, 48:1693-1700 Ulloa L, Batliwalla FM, Andersson U, Gregersen PK, Tracey KJ: High mobility group box chromosomal protein as a nuclear 19 20 21 22 23 24 25 26 27 28 protein, cytokine, ... mechanisms in RAGE signalling [7] R 822 NS 22 00 1800 Soluble RAGE (pg/ml) Blood sRAGE (pg/ml) Figure 20 00 1800 1600 P < 0.05 1400 120 0 1000 800 600 400 20 0 RA blood 976 ± 1 42 (787) 777 ± 81 (699) RA synovial...
Ngày tải lên: 09/08/2014, 06:23
Báo cáo y học: "erum levels of soluble receptor for advanced glycation end products and of S100 proteins are associated with inflammatory, autoantibody, and classical risk markers of joint and vascular damage in rheumatoid arthritis" doc
... Confidence interval ACPA 2. 23 0 .27 8.34 < 0.001 1.70 to 2. 76 Age -0.03 0.01 -2. 15 0.03 -0.06 to -0.0 02 RF 2. 21 0 .26 8.33 < 0.001 1.68 to 2. 73 Carriage of HLA-DRB1*0401 1.05 0. 32 3 .26 0.001 0.41–1.69 ... 0.001 0 .22 to 0.75 S100A12a 0.67 0.16 4 .23 < 0.001 0.36 to 0.99 sRAGEa -0.77 0.31 -2. 51 0.01 -1.37 to -016 1.45 0 .28 5. 12 < 0.001 0.89 to 2. 01 Multivariate analysis: RF ACPA 1 .22 0 .29 4 .24 < 0.001 ... membrane J Rheumatol 1999, 26 :25 23 -25 28 62 Hsu K, Passey RJ, Endoh Y, Rahimi F, Youssef P, Yen T, Geczy CL: Regulation of S100A8 by glucocorticoids J Immunol 20 05, 174 :23 18 -23 26 63 Cheng P, Corzo CA,...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: ":The expression of the receptor for advanced glycation end-products (RAGE) in RA-FLS is induced by IL-17 via Act-1" ppsx
... Arthritis Research & Therapy 20 11, 13:R113 http://arthritis-research.com/content/13/4/R113 Received: October 20 10 Revised: May 20 11 Accepted: 12 July 20 11 Published: 12 July 20 11 References Schmidt ... surface J Biol Chem 19 92, 26 7:14987-14997 Peppa M, Uribarri J, Vlassara H: Advanced glycoxidation A new risk factor for cardiovascular disease? Cardiovasc Toxicol 20 02, 2: 275 -28 7 Ramasamy R, Vannucci ... Arthritis Res Ther 20 04, 6:R 120 - 128 26 Pickens SR, Volin MV, Mandelin AM, Kolls JK, Pope RM, Shahrara S: IL-17 contributes to angiogenesis in rheumatoid arthritis J Immunol 184: 323 3- 324 1 27 Kotake S,...
Ngày tải lên: 12/08/2014, 17:22
Báo cáo khoa học: Analysis and biological relevance of advanced glycation end-products of DNA in eukaryotic cells ppt
... transition 338 fi 178 was used as quantifier 106 4.0E+05 0.0E+00 29 4 [M- CO2- H] 149 25 50 75 100 125 150 175 20 0 22 5 25 0 27 5 300 325 350 m/z Accumulation of CEdGA,B in hepatic stellate cells in ... 1.58 · 10)4 2. 00 · 10)3 6. 42 · 10)3 6.37 · 10)4 8.36 · 10)3 1.55 · 10 )2 1.54 · 10)3 9.95 · 10)3 1.94 · 10 )2 FEBS Journal 27 5 (20 08) 914– 925 ª 20 08 The Authors Journal compilation ª 20 08 FEBS 917 ... mammalian cells by plasmid DNA Mol Cell Biol 7, 27 45 27 52 FEBS Journal 27 5 (20 08) 914– 925 ª 20 08 The Authors Journal compilation ª 20 08 FEBS 925 ...
Ngày tải lên: 30/03/2014, 04:20
Báo cáo y học: " Soluble receptor for advanced glycation end products in COPD: relationship with emphysema and chronic cor pulmonale: a case-control study" potx
... Bierhaus A, Miniati et al Respiratory Research 20 11, 12: 37 http://respiratory-research.com/content/ 12/ 1/37 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Oury TD: A role for the receptor for advanced ... corticosteroids Oral theophylline 71 (60) 22 (18) 57 (70) 26 ( 32) 0.135 0.030 Cardiovascular drugs 80 (67) 42 ( 52) 0.039 Diuretics 28 (24 ) 24 (30) 0.4 12 Statins 25 (21 ) 12 (15) 0.354 QoL questionnaire, ... 0.999 465-1039 0.3 52 Heart failure 0.376 Diabetes mellitus yes 22 920 735-1 123 no Dyslipidemia 178 630 475-1069 yes 61 681 508-1078 no 139 631 480-10 62 yes 128 6 42 4 82- 1076 no 72 671 484-1078 37...
Ngày tải lên: 12/08/2014, 13:22
Báo cáo y học: "Mechanical ventilation during experimental sepsis increases deposition of advanced glycation end products and myocardial inflammation" pdf
... cells/mm2, non-ventilated sepsis 2. 1 ± 0.6 cells/mm2, P < 0.05) and RV (LTV 11.3 ± 1.9 cells/mm2, HTV 12. 2 ± 2. 1 cells/mm2; non-ventilated sepsis 5.5 ± 1.5 cells/mm2, P < 0.001; Figure 3) In general, ... Med 20 08, 178:356-3 62 22 Bohnen JM, Matlow AG, Mustard RA, Christie NA, Kavouris B: Antibiotic efficacy in intraabdominal sepsis: a clinically relevant model Can J Microbiol 1988, 34: 323 - 326 23 ... atherosclerotic blood vessels Atherosclerosis 20 04, 174 :28 7 -29 2 25 Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis N Engl J Med 20 03, 348:138-150 26 Weber SU, Schewe JC, Lehmann LE,...
Ngày tải lên: 13/08/2014, 16:21
Báo cáo khoa học: Advanced glycation end products and lipopolysaccharide synergistically stimulate proinflammatory cytokine⁄chemokine production in endothelial cells via activation of both mitogen-activated protein kinases and nuclear factor-jB pdf
... 3000 120 0 1800 800 20 0 120 0 400 600 0 400 24 12 Incubation time (h) * 1000 800 pg·mL–1 B * 600 * 400 * 20 0 C 10 100 1000 LPS (ng·mL–1) * 125 * 100 pg·mL–1 AGE-HSA LPS 24 00 * 3000 25 00 20 00 1500 ... 500 * * 50 * 25 50 12. 5 25 50 100 HSA AGE-HSA (µg·mL–1) * * 4000 320 0 * * * 800 10 100 1000 LPS (ng·mL–1) 1000 * * 600 * 10 100 1000 LPS (ng·mL–1) 25 00 * 20 00 * 1500 1000 400 24 12 Incubation ... 1500 1000 400 24 12 Incubation time (h) 1600 20 0 0 24 00 800 75 24 12 Incubation time (h) * * 50 12. 5 25 50 100 HSA AGE-HSA (µg·mL–1) * 500 0 * 50 12. 5 25 50 100 HSA AGE-HSA (µg·mL–1) Fig (A) Time-...
Ngày tải lên: 30/03/2014, 01:20
Báo cáo y học: "Advanced glycation end products induce cell cycle arrest and proinflammatory changes in osteoarthritic fibroblast-like synovial cells" doc
... and beyond Arthritis Rheum 20 07, 56 :24 82- 2489 Lories RJ: Joint homeostasis, restoration, and remodeling in osteoarthritis Best Pract Res Clin Rheumatol 20 08, 22 :20 9 -22 0 Drinda S, Franke S, Canet ... Immunol 20 08, 1 52: 415- 422 41 Wittrant Y, Gorin Y, Woodruff K, Horn D, Abboud HE, Mohan S, Abboud-Werner SL: High D(+)glucose concentration inhibits RANKL-induced osteoclatogenesis Bone 20 08, 42: 1 122 -1130 ... vascular endothelial cells J Biol Chem 20 00, 27 5 :25 781 -25 790 37 Baier A, Meineckel I, Gay S, Pap T: Apoptosis in rheumatoid arthritis Curr Opin Rheumatol 20 03, 15 :27 4 -27 9 38 Bohlender JM, Franke S, Stein...
Ngày tải lên: 09/08/2014, 14:22
Báo cáo y học: " Blockade of advanced glycation end product formation attenuates bleomycin-induced pulmonary fibrosis in rats" pot
... of (page number not for citation purposes) Respiratory Research 20 09, 10:55 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 Nakai A, Satoh M, Hirayoshi K, Nagata K: Involvement of the stress ... Pulmonary Fibrosis Am J Respir Cell Mol Biol 20 02, 27 (2) : 122 - 124 Ulrich P, Cerami A: Protein glycation, diabetes, and aging Recent Prog Horm Res 20 01, 56:1 -21 Bohlender JM, Franke S, Stein G, Wolf ... 20 04, 27 9(19):19816-19 823 Dafforn TR, Della M, Miller AD: The molecular interactions of heat shock protein 47 (Hsp47) and their implications for collagen biosynthesis J Biol Chem 20 01, 27 6( 52) :49310-49319...
Ngày tải lên: 12/08/2014, 14:20
báo cáo hóa học: " Imaging the effect of receptor for advanced glycation endproducts on angiogenic response to hindlimb ischemia in diabetes" docx
... to 2. 79), and for the WT diabetic group, it was 1.38 ± 0 .26 (range, 1.05 to 1.74) (P < 0.001) (Figure 2A) The mean value for the RAGE-/- non-diabetic group was 2. 02 ± 0 .29 (range, 1.54 to 2. 62) ... after murine hindlimb ischemia Circulation 20 05, 111: 325 5- 326 0 Tekabe et al EJNMMI Research 20 11, 1:3 http://www.ejnmmires.com/content/1/1/3 Page of 22 Meoli DF, Sadeghi MM, Krassilnikova S, Bourke ... glygation endproducts is involved in imapaired angiogenic response in diabetes Diabetes 20 06, 55 :22 45 -22 55 Tamarat R, Silvestre J-S, Huijberts M, Benessiano J, Ebrahimian TG, Duriez M, Wautier...
Ngày tải lên: 21/06/2014, 02:20
Báo cáo y học: "Green tea polyphenol epigallocatechin-3-gallate inhibits advanced glycation end product-induced expression of tumor necrosis factor-α and matrix metalloproteinase-13 in human chondrocyte" ppsx
... Rheumatol 20 02, 14:585-589 Page 12 of 13 (page number not for citation purposes) 19 20 21 22 23 24 25 26 27 28 DeGroot J, Verzijl N, Bank RA, Lafeber FP, Bijlsma JW, TeKoppele JM: Age-related ... antibody (# 924 2), anti-phospho-p38 MAPK antibody (# 921 5S), anti-p38 MAPK antibody (# 921 2), anti-phospho-SAPK/JNK antibody (# 925 1S), antiSAPK/JNK antibody (# 925 2), anti-phospho ERK P44/ 42 MAPK antibody ... 330/em 395 nm] 754.6 ± 17 .2* * 83 .2 ± 5.7 Fluo [ex 365/em 440 nm] 741.4 ± 28 .1** 84.8 ± 5 .2 Fluo [ex 485/em 530 nm] 734.1 ± 20 .4** 85.1 ± 5.3 Fluo [ex 28 0/em 350 nm] 733 .2 ± 19.1** 84.0 ± 4.4 Data...
Ngày tải lên: 09/08/2014, 14:20
báo cáo hóa học:" RAGE (Receptor for Advanced Glycation Endproducts), RAGE Ligands, and their role in Cancer and Inflammation" pptx
... of proteins J Biol Chem 19 92, 26 7:14998-15004 Page 16 of 21 (page number not for citation purposes) Journal of Translational Medicine 20 09, 7:17 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 ... Medicine 20 03, 9 :28 7 -29 3 Franz C, Durussel I, Cox JA, Schafer BW, Heizmann CW: Binding of Ca2+ and Zn2+ to Human Nuclear S100A2 and Mutant Proteins J Biol Chem 1998, 27 3:18 826 -18834 Page 18 of 21 (page ... Cdc 42 J Biol Chem 20 08, 28 3:34457-34468 Foell D, Wittkowski H, Roth J: Mechanisms of Disease: a 'DAMP' view of inflammatory arthritis Nature Clinical Practice Rheumatology 20 07, 3:3 82- 390 20 21 22 ...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... 1.5 12. 7 ± 1.5 12. 9 ± 1.6 Hemoglobin (mg/dl) Glucose (mg/dl) 13.0 ± 1.9 100 ± 30 1 02 ± 40 99 ± 25 1 02 ± 42 IgG (mg/dl) 1 427 ± 529 * 11 82 ± 378 125 2 ± 369 122 6 ± 443 IgM (mg/dl) 139 ± 61 1 52 ± 88 ... ± 61* 140 ± 88 IgA (mg/dl) 28 5 ± 139 23 6 ± 104 28 2 ± 126 23 2 ± 106 19 (40%) 69 (36%) 45 (69%)* 25 % (n) 18 (26 %) 40 (21 %) 50 (77%) – Anti-AGE-IgG3+ (n) 12 (26 %) 38 (20 %) 49 (76%) – RF+ (%) Anti-AGE-IgG1+ ... 85 94 82 43 (61%) 27 (73%) 27 (63%) 60 (67%) Age (years) 47 ± 12* † 43 ± 15 38 ± 11* 41 ± 14† Symptom duration (weeks) 32 ± 18 29 ± 26 45 ± 59 29 ± 19 Swollen joint count 13 ± 14 ± 10 2 2 3±4 Total...
Ngày tải lên: 09/08/2014, 01:21
Báo cáo y học: "No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis" pdf
... 16/ 12 0.45 13/8 0 .28 12/ 9 0.51 GCT 28 /31 0.7 21 /27 0.39 22 /26 0.56 GTC 12/ 11 0.83 10/7 0.47 9/7 0. 62 TCC 20 /21 0.88 18 /20 0.75 18/19 0.87 Linkage disequilibrium: TLR1_SNP1 (rs5743618) – TLR1_SNP2 ... 0.53 TLR2 TLR4 rs2737191 (-3869) 38/35 0.73 33/36 0. 72 38/ 42 0.65 rs4986790 (+8719 D259G) 7/9 0. 62 9/ 12 0.51 10/11 0.83 rs1554973 (+1 422 9) 30/30 25 /25 32/ 31 0.9 TLR6 rs5743810 (+744 S249P) 48/41 ... (+7765 S602I) 33 /28 0. 52 34 /29 0.53 32/ 32 rs5743594 (+3663) 15 /22 0 .25 14 /20 0.3 20 /21 0.88 rs3804099 (+15591 N199N) 39/40 0.91 41/36 0.57 47/39 0.39 rs4696480 (-1938) 46/39 0.45 41/44 0.74 42/ 48...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo y học: "Vitamin D receptor gene polymorphisms and susceptibility of hand osteoarthritis in Finnish wome" pdf
... 363 .2 245 186 21 6 21 5 99 3 32 Yes 110 (21 %) 56.5 ± 4.6 25 .1 ± 3.8 688.1 ± 403.8 48 (16%) 62 (25 %) 72 (25 %) 38 (15%) 20 (17%) 90 (21 %) No 504 (93%) 53.6 ± 5 .2 24.4 ± 3.6 669.4 ± 371.0 27 2 23 2 26 4 24 0 ... 53.0 ± 5 .2 24.3 ± 3.5 663 .2 ± 356.3 22 3 160 187 196 88 29 7 160 (29 %) 56.3 ± 4.7 25 .0 ± 3.8 707.7 ± 403.8 72 (24 %) 88 (35%) 103 (35%) 57 (22 %) 33 (28 %) 127 (30%) No 431 (79%) 53.3 ± 5 .2 24.3 ± 3.5 ... ApaIb AA 51/ 123 1.0 29 /145 1.0 18/156 1.0 Aa 77/191 0.98 (0. 62 1.54) 56 /21 2 1.43 (0.84 2. 42) 14 /25 4 0.46 (0 .21 –1.00) aa 32/ 69 1 .20 (0.67 2. 15) 25 /76 1.93 (1.00–3.70) 7/94 0.65 (0 .24 –1.75) 'A'...
Ngày tải lên: 09/08/2014, 07:20
Báo cáo y học: "No evidence of major effects in several Toll-like receptor gene polymorphisms in rheumatoid arthritis" ppt
... 16/ 12 0.45 13/8 0 .28 12/ 9 0.51 GCT 28 /31 0.7 21 /27 0.39 22 /26 0.56 GTC 12/ 11 0.83 10/7 0.47 9/7 0. 62 TCC 20 /21 0.88 18 /20 0.75 18/19 0.87 Linkage disequilibrium: TLR1_SNP1 (rs5743618) – TLR1_SNP2 ... 0.53 TLR2 TLR4 rs2737191 (-3869) 38/35 0.73 33/36 0. 72 38/ 42 0.65 rs4986790 (+8719 D259G) 7/9 0. 62 9/ 12 0.51 10/11 0.83 rs1554973 (+1 422 9) 30/30 25 /25 32/ 31 0.9 TLR6 rs5743810 (+744 S249P) 48/41 ... (+7765 S602I) 33 /28 0. 52 34 /29 0.53 32/ 32 rs5743594 (+3663) 15 /22 0 .25 14 /20 0.3 20 /21 0.88 rs3804099 (+15591 N199N) 39/40 0.91 41/36 0.57 47/39 0.39 rs4696480 (-1938) 46/39 0.45 41/44 0.74 42/ 48...
Ngày tải lên: 09/08/2014, 13:22
Báo cáo y học: " Glucocorticoid receptor gene polymorphisms associated with progression of lung disease in young patients with cystic fibrosis" doc
... (± 2. 9) 96 .2 (± 4.1) 88.8 (± 6.7) -2. 5 (± 0.5) -2. 9 (± 0.7) -1.6 (± 1.1) 0.7 89 .2 (± 4.1) 98.7 (± 5.4) 94.4 (± 8.4) -2. 2 (± 0.7) -3.8 (± 0.9) -2. 2 (± 1.3) 0.4 ER 22/ 23EK GG AA + AG 95 .2 (± 11 .2) ... (9.6) -3.0 (± 2. 2) -3.0 (± 2. 2) 0.5 BclI CC CG GG 96.4 (± 2. 8) 90.7 (± 3.9) 106.8 (± 6.4) -2. 3 (± 0.5) -2. 8 (± 0.7) -3.4 (± 1 .2) 0. 02* 92. 0 (± 3.7) 89.3 (± 5 .2) 111.0 (± 7 .2) -2. 3 (± 0.6) -3.1 ... of (page number not for citation purposes) Respiratory Research 20 07, 8:88 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 Balfour-Lynn IM, Klein NJ, Dinwiddie R: Randomised controlled...
Ngày tải lên: 12/08/2014, 15:21
Tài liệu Báo cáo khoa học: Complex transcriptional and translational regulation of iPLA2c resulting in multiple gene products containing dual competing sites for mitochondrial or peroxisomal localization docx
... Chem 27 2, 8567–8575 25 Stewart, A., Ghosh, M., Spencer, D.M & Leslie, C.C (20 02) Enzymatic properties of human cytosolic phospholipase A (2) gamma J Biol Chem 27 7, 29 526 29 536 26 Mancuso, D.J., ... of mammalian iPLA2s J Biol Chem 27 7, 328 07– 328 14 15 Broekemeier, K.M., Iben, J.R., Levan, E.G., Crouser, E.D & Pfeiffer, D.R (20 02) Pore formation and uncoupling initiate a Ca2+-independent degradation ... K+ channel (Kv1.1) by Ca2+-independent phospholipase A2 J Biol Chem 27 0, 28 85– 28 88 20 Smani, T., Zakharov, S.I., Csutora, P., Leno, E., Trepakova, E.S & Bolotina, V.M (20 04) A novel mechanism...
Ngày tải lên: 19/02/2014, 16:20