pcs and advanced oxidation products aopps in renal disorders

Báo cáo khoa học: Insulin induces heme oxygenase-1 through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in renal cells pptx

Ngày tải lên : 07/03/2014, 12:20

... Insulin is a polypeptide hormone that regulates glucose, lipid and protein metabolism and promotes cell growth and differentiation On ligand binding, the insulin receptor tyrosine kinase initiates ... (CHX) was administered to establish the role of protein synthesis in insulin-induced HO-1 expression (Fig 2B,C) CHX abrogated HO-1 protein induction following insulin treatment but, in agreement ... sensitive to PI3K ⁄ Akt inhibition and Nrf2 gene silencing The fold-increase in both HO-1 protein and mRNA in response to insulin was consistent, as well as being time and concentration dependent...

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Báo cáo y học: "Cholesterol-crystal embolism presenting with delayed graft function and impaired long-term function in renal transplant recipients: two case reports" potx

Ngày tải lên : 11/08/2014, 17:21

... period was 46 and 65 minutes, and cold kidney ischemia lasted for 11 hours 40 minutes and 19 hours minutes Both patients received quadruple immunosuppression consisting of a calcineurin inhibitor, ... detrimental effect on renal function during longterm use of fluvastatin in renal transplant recipients in the Assessment of Lescol in Renal Transplantation (ALERT) study Clin Transplant 2006, 20:732-739 ... count Figure Renal allograft dysfunction (serum creatinine including the 1-year follow-up) following cholesterol-crystal embolism in two kidney recipients from the same deceased donor Renal- transplant...

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Báo cáo y học: "Receptor for advanced glycation end products Glycine 82 Serine polymorphism and risk of cardiovascular events in rheumatoid arthritis" potx

Ngày tải lên : 09/08/2014, 10:20

... with aging, diabetes and renal failure, and at sites of inflammation (by oxidation) [16] Levels of S100 proteins and HMGB1 are increased in both adult and juvenile RA [17], and inhibition of the ... protein (HMGB1)), β-pleated sheet fibrils of amyloid and advanced glycation end products (AGEs) [15] AGEs are the products of nonenzymatic glycation and oxidation of proteins that form with aging, ... examined only RA patients and not matched non-RA controls and inflammatory markers and radiographs were examined at only a single time point, which occurred at variable times after commencing...

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Báo cáo y học: "Glucosamine prevents in vitro collagen degradation in chondrocytes by inhibiting advanced lipoxidation reactions and protein oxidation" pdf

Ngày tải lên : 09/08/2014, 10:20

... purposes) inhibiting advanced lipoxidation reactions Specifically, glucosamine inhibited purified lipoprotein protein oxidation and aldehydic oxidation of chondrocyte matrix Using this in vitro ... potent advanced lipoxidation inhibitory activities in a variety of tests [38,39] In addition to showing advanced lipoxidation inhibitory activity, these compounds show inhibitory activity against advanced ... are being evaluated in clinical trials for the treatment of diabetic nephropathy [40] Aminoguanidine inhibits chemical modification of proteins during lipid peroxidation reactions and inhibits...

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Báo cáo y học: " Factors affecting the long-term response to tacrolimus in renal transplant patients: Pharmacokinetic and pharmacogenetic approac"

Ngày tải lên : 26/10/2012, 09:32

... of a combination of a calcineurin inhibitor (tacrolimus) with a purine inhibitor (mycophenolate mofetil or azathioprine) and a steroid (prednizolone) Tacrolimus was given twice a day in individually ... seriousness, co-administrated drug therapies and their interactions, renal and hepatic function, nutritional and other habbits, are often responsible for the intra- and inter-individual variability ... Hesselink DA, van Schaik RH, van der Heiden IP, et al Genetic polymorphisms of the CYP3A4, CYP3A5, and MDR-1 genes and pharmacokinetics of the calcineurin inhibitors cyclosporine and tacrolimus Clin...

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ANALYSIS OF HYDROXYL RADICAL GENERATION IN ADVANCED OXIDATION PROCESS -EFFECT OF HUMIC SUBSTANCES DURING OZONATION

Ngày tải lên : 05/09/2013, 08:40

... V., Insola A and Marotta R (1999) Advanced oxidation processes (AOP) for water purification and recovery Cat Tod., 52, 51-59 Bader H and Hoigne J (1981) Determination of ozone in water by the indigo ... DMPO-OH increased gradually with time after mixing, and the initial velocities of DMPO-OH generation increased in both ozone- and 3-chlorophenol-dose dependent manner (data not shown) In order ... occurring in huge amounts in soils, sediments and waters as a product of the chemical and biological transformation of animal and plant residues A substantial proportion of carbon-containing substances...

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The Potential of Biofumigants as Alternatives to Methyl Bromide for the Control of Pest Infestation in Grain and Dry Food Products

Ngày tải lên : 25/10/2013, 05:20

... protection has increased and stands as the main alternative to methyl bromide Lately, insect resistance to phosphine has become an important issue for effective grain treatment (Nakakita and Winks, 1981; ... essential oils and their terpenoids, and their use in cosmetics and as ﬂavoring agents in food and beverages, is a good indication of their relative safety to warm-blooded animals and humans They ... Indole alkaloid pathway, 26 Induced systemic resistance(ISR), 146 Induction of Defense Metabolism, 154 Industrial sector, 107–116 Inteins, 83 Intellectual Property Rights, 378 International Institute...

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Tài liệu Risk Characterization, Assessment, and Management of Organic Pollutants in Beneficially Used Residual Products pdf

Ngày tải lên : 14/02/2014, 03:20

... sample Each cleanup step is intended to eliminate interfering compounds by using physical or chemical properties that differ between interfering compounds and the analyte of interest The analytical ... used in the model, the more representative the model output can be of land application at field scales The intent of introducing this approach is to encourage all involved in sustainable land ... following cleanup techniques, a reporting limit that is achievable for the sample should be determined This reporting limit should be reported and qualified by indicating the presence of an interference...

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Tài liệu 2012 Outlook for the retail and Consumer Products Sector in Asia ppt

Ngày tải lên : 18/02/2014, 21:20

... retailing Online retailing in Asia will continue to grow strongly on the back of rapid leading markets, Japan and South Korea, losing share to China and 22 infrastructure and in payment and security ... (B2C) testing out retail opportunities beyond the increasingly saturated and pricey Tier cities and recognising the growing spending power of those in also seeing more brands and industries Internet ... cosmetics and toiletries, behind the dominates the market, accounting for luxury products in 2012, to promote demand for consumer goods in Asia has remained strong, and demand for increasingly shifting...

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Báo cáo khoa học: Expression of cholinesterases in human kidney and its variation in renal cell carcinoma types pdf

Ngày tải lên : 06/03/2014, 22:21

... al ˜ Cholinesterases in renal carcinomas Results Cholinesterase activity in human kidney and renal tumours Butyrylcholinesterase activity predominated over acetylcholinesterase activity in healthy ... muscarinic and nicotinic receptors [34,55] support a role for ACh in renal tubules The increase in cholinesterase activity in pRCC, the subsequent decrease in ACh availability and the lowered cholinergic ... acetylcholinesterase and butyrylcholinesterase seem to play noncatalytic roles, which would explain their wide distribution in tissues and cells [16], including stem cells [17] Increasing evidence links...

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Báo cáo khoa học: Transient potential receptor channel 4 controls thrombospondin-1 secretion and angiogenesis in renal cell carcinoma ppt

Ngày tải lên : 07/03/2014, 05:20

... Thrombospondin-1 loss in renal cancer A B Fig Role of TSP1 in angiogenesis, and localization in renal cells and tissue (A) Sections of RCC tumors and adjacent normal tissue (HNK) were stained for TSP1 and ... these include angiostatin, endostatin, tumstatin, PEDF, SPARC (secreted protein, acidic and rich in cysteine), tissue inhibitor of metalloproteinases (TIMPs) and TSP1 An emerging concept is to view ... calcium-binding protein, calbindin D28K [28] (Fig 3C) In normal kidney, calbindins transport calcium ions across the glomerular epithelium and serve as buffers, to prevent toxic concentrations of intracellular...

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Topicc in renal biopsy and pathology dited by Muhammed Mubarak and Javed I. Kazi. doc

Ngày tải lên : 30/03/2014, 19:20

... open renal biopsy Renal and surrounding anatomy Technique to use and position of the biopsy needle Examining and handling tissue for histologic processing Complications and how to detect and treat ... little or no training, or some training but not enough to feel competent in doing renal biopsy independently (Berns, 2010) Skills Cognitive skills Knowledge of: Indications and contraindications ... routinely and includes complete biochemical profile, complete blood count and urinalysis Baseline coagulation parameters, including platelet count, prothrombin time, partial thromboplastin time and...

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principles and advanced methods in medical imaging and image analysis (wsp, 2008)

Ngày tải lên : 05/06/2014, 11:52

... PRINCIPLES AND ADVANCED METHODS IN MEDICAL IMAGING AND IMAGE ANALYSIS This page intentionally left blank PRINCIPLES AND ADVANCED METHODS IN MEDICAL IMAGING AND IMAGE ANALYSIS ... called a coincidence detection indicating the origin of annihilation along the line joining the two detectors involved in coincidence detection Thus, by detecting a large number of coincidences, ... Brent Lu, in Chapter 22, describes knowledge mining and decision making strategies for medical imaging applications in radiation therapy planning and treatment With large image archiving and communication...

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Báo cáo sinh học: "Characterization and targeting of phosphatidylinositol-3 kinase (PI3K) and mammalian target of rapamycin (mTOR) in renal cell cancer" docx

Ngày tải lên : 18/06/2014, 22:20

... advantageous pharmacologic profile and in vivo administration results in high and sustained exposure in tumor tissue [49] It inhibits both mTORC1 and mTORC2, resulting in enhanced inhibition of p-Akt compared ... Ernstoff MS, et al: Randomized phase III trial of high-dose interleukin-2 versus subcutaneous interleukin2 and interferon in patients with metastatic renal cell carcinoma J Clin Oncol 2005, 23:133-141 ... Phosphoinositide 3-kinase in disease: timing, location, and scaffolding Curr Opin Cell Biol 2005, 17:141-149 Marone R, Cmiljanovic V, Giese B, Wymann MP: Targeting phosphoinositide 3-kinase: moving...

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