pathogenesis of celiac disease ppt
Prevalence of Celiac disease in Turkish children with type 1 Diabetes Mellitus and their non-diabetic first-degree relatives pptx
... Magazzù G, Greco L. Duration of exposure togluten and risk for autoimmune disorders in patients with celiac disease. SIGEP Study Group for Autoimmune Disor-ders in Celiac Disease. Gastroenterology ... Prevalence of celiac disease in a sample of Turkish children and adoles-cents with type 1 diabetes mellitus. J Clin Gastroenterol2006; 40: 655-7.4. Tanure MG, Silva IN, Bahia M, et al. Prevalence of ... Development of ce-liac disease- associated antibodies in offspring of parentswith type I diabetes. Diabetologia 2000; 43: 1005-11.7. Jaeger C, Hatziagelaki E, Petzoldt R, et al. Comparativeanalysis of...
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Báo cáo Y học: The analysis of the fine specificity of celiac disease antibodies using tissue transglutaminase fragments pot
... Igs found in the serum of celiac disease patients.Keywords: autoimmunity; celiac disease; transglutaminase;epitope mapping; phage display. Celiac disease (CD) is a genetic disease strongly linked ... Greco, L. (1999) Duration of exposure to gluten and risk for autoimmune disorders inpatients with celiac disease. SIGEP Study Group forAutoimmune Disorders in Celiac Disease. Gastroenterology ... Schematic drawing of the cloning of 12 different tTG regions.Reference numbers of the amino acid residues at the ends of the clonedsequences are shown.Ó FEBS 2002 Epitope mapping of anti-tTG Igs...
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Báo cáo y học: "Hypoxia in the pathogenesis of systemic sclerosis" ppt
... [79]found increased levels of CTGF mRNA and protein infibroblasts exposed to 1% of oxygen or treated with cobaltchloride, a chemical stabilizer of HIF-1α. The induction of CTGF in response to hypoxia ... hypoxia might beactively involved in pathogenesis of SSc by stimulating therelease of extracellular matrix protein. This could result in avicious circle of hypoxia and fibrosis. Hypoxia stimulates ... excessive deposition of matrix might impair further the diffusion of oxygen andcause a vicious circle of hypoxia and tissue fibrosis. Currently,there are no specific modulators of HIFs or PHDs availablefor...
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Báo cáo y học: " High-mobility group box protein 1 (HMGB1): an alarmin mediating the pathogenesis of rheumatic disease." docx
... variety of immunologically mediated conditions that rangefrom sepsis to autoimmunity. Of these diseases, rheumatoidarthritis (RA) shows the clearest evidence for involvement of HMGB1 in pathogenesis. ... releaseproinflammatory cytokines.The role of HMGB1 in systemic lupuserythematosusStudies on patients with lupus support a role of HMGB1 in disease manifestations. Thus, biopsies of skin of patients withcutaneous ... research. This review willsummarize the role of HMGB1 in the pathogenesis of therheumatic diseases and its potential as a therapeutic target.Concept of an alarminMammalian organisms have evolved...
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Báo cáo khoa học: "Effects of cyclosporin A treatment on the pathogenesis of avian leukosis virus subgroup J infection in broiler chickens with Marek’s disease virus exposure" ppt
... hatching until the end of experiment. Some of thechickens from each treatment group were infected with anisolate of ALV-J, ADOL-7501, at 2 weeks of age. Theeffects of viral infection were ... enhancement of mitogen response inchickens infected with Marek's disease virus and theherpesvirus of turkeys. Infect. Immun. 1978, 21, 474-479.26.Lillehoj, H. S. Effects of immunosuppression ... analyzedusing two-tailed Student t-test with assumption of differentvariance. Significance of differences in percentage of viremia, antibody and the results of histopathology wasdetermined by Chi-square...
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Tài liệu Growth and nutritional status of children with homozygous sickle cell disease ppt
... Ipadeola T. Clinical trial of riboflavin in sickle cell disease. East Afr Med J1993; 70:418–21.114 Clarke R. Homocysteine-lowering trials for pre-vention of heart disease and stroke. Semin ... levels of LH and FSHwere higher in patients than in controls atthe same stage of development of secondarysexual characteristics. This suggested avariation in the rate of maturation of thehypothalamic–pituitary ... stimula-tion tests and the conflicting results of hormonal assessment make it difficult toevaluate the role of endocrinal dysfunctionin the pathogenesis of growth impairment.Endocrine function is...
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Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... the inhibition of CYP activity observed in theabsence of changes in protein expression in rabbit he-patocytes [22]. ROS indirectly reduced the activity of selected isoforms of CYP by inducing ... compilation ê 2011 FEBS Role of Kupffer cells in pathogenesis of sepsis-induceddrug metabolizing dysfunctionTae-Hoon Kim*, Sang-Ho Lee* and Sun-Mee LeeSchool of Pharmacy, Sungkyunkwan University, ... studies suggestthat some of the effects of HMGB1 result from itsinteraction with TLR2 or TLR4, leading to the media-tion of various cellular responses and the release of proinflammatory cytokines...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... Department of Neurodegenerative Disease, Institute of Neurology, London, UKParkinson’s disease (PD) is a common neurodegenera-tive disease which affects over 1% of people over theage of 65 years ... that some of the genes involved in thegenetics of Lewy body disease, have in common thefact that they impinge on ceramide metabolism. Oneshortfall of the present theory is the lack of neuro-pathological ... of thedisorder, which often results in severe distal sensoryloss and mutilating acropathy [32]. Although muta-tions in SPTLC1 cause neurological disease, there is,as yet, no description of...
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Tài liệu GLOBAL STRATEGY FOR THE DIAGNOSIS, MANAGEMENT, AND PREVENTION OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE pptx
... tuber--izations. Another way of estimating the morbidity burden of disease is to calculate years of living with disability (YLD). The Global Burden of Disease Study estimates that COPD ... underdi-extent of the underreporting varies across countries and depends on the level of awareness and understanding of COPD among health professionals, the organization of health care services ... of disease burden that are consistent and measurable across nations. The authors of the Global Burden of Dis-ease Study designed a method to estimate the fraction of mortality...
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Tài liệu THE MANAGEMENT OF SICKLE CELL DISEASE ppt
... Study of Sickle Cell Disease (CSSCD) identified earlypredictors of clinical severity such as dactylitisbefore 12 months of age, average Hb level of less than 7 g/dL in the second year of life, ... frequency of urinary tract infection in a large study of patients in U.S.Department of Veterans Affairs’ hospitals (9). AUTOSOMAL DOMINANT POLYCYSTICKIDNEY DISEASE The incidence of end-stage ... M.D.President Emeritus, Sickle Cell Disease Association of AmericaDistinguished Professor of Pediatrics and Associate DeanWayne State University School of MedicineScott Hall, Room 1201540...
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Tài liệu The Diagnosis, Evaluation, and Management of von Willebrand Disease ppt
... Technical report13. Validation studies14. Review of reported cases (review of known cases of a disease) 15. Case reportsUpon examination of the yield of the initial literaturesearch, it was determined ... hematologists). Ad hoc members of thePanel represented the Division of Blood Diseases and Resources of the NHLBI. The Panel was coordinated by the Division for the Application of Research Discoveries ... approximately 98 percent of indexcases, 89 percent of affected relatives, 32 percent of unaffected relatives, and 12 percent of healthy controls. The major symptoms of affected persons(excluding...
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