pathogenesis of celiac disease ppt

... Magazzù G, Greco L. Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. SIGEP Study Group for Autoimmune Disor- ders in Celiac Disease. Gastroenterology ... Prevalence of celiac disease in a sample of Turkish children and adoles- cents with type 1 diabetes mellitus. J Clin Gastroenterol 2006; 40: 655-7. 4. Tanure MG, Silva IN, Bahia M, et al. Prevalence of ... Development of ce- liac disease- associated antibodies in offspring of parents with type I diabetes. Diabetologia 2000; 43: 1005-11. 7. Jaeger C, Hatziagelaki E, Petzoldt R, et al. Comparative analysis of...

Ngày tải lên: 05/03/2014, 12:20

Ngày tải lên: 10/08/2014, 16:23

... Igs found in the serum of celiac disease patients. Keywords: autoimmunity; celiac disease; transglutaminase; epitope mapping; phage display. Celiac disease (CD) is a genetic disease strongly linked ... Greco, L. (1999) Duration of exposure to gluten and risk for autoimmune disorders in patients with celiac disease. SIGEP Study Group for Autoimmune Disorders in Celiac Disease. Gastroenterology ... Schematic drawing of the cloning of 12 different tTG regions. Reference numbers of the amino acid residues at the ends of the cloned sequences are shown. Ó FEBS 2002 Epitope mapping of anti-tTG Igs...

Ngày tải lên: 08/03/2014, 09:20

... [79] found increased levels of CTGF mRNA and protein in fibroblasts exposed to 1% of oxygen or treated with cobalt chloride, a chemical stabilizer of HIF-1α. The induction of CTGF in response to hypoxia ... hypoxia might be actively involved in pathogenesis of SSc by stimulating the release of extracellular matrix protein. This could result in a vicious circle of hypoxia and fibrosis. Hypoxia stimulates ... excessive deposition of matrix might impair further the diffusion of oxygen and cause a vicious circle of hypoxia and tissue fibrosis. Currently, there are no specific modulators of HIFs or PHDs available for...

Ngày tải lên: 09/08/2014, 01:22

... variety of immunologically mediated conditions that range from sepsis to autoimmunity. Of these diseases, rheumatoid arthritis (RA) shows the clearest evidence for involvement of HMGB1 in pathogenesis. ... release proinflammatory cytokines. The role of HMGB1 in systemic lupus erythematosus Studies on patients with lupus support a role of HMGB1 in disease manifestations. Thus, biopsies of skin of patients with cutaneous ... research. This review will summarize the role of HMGB1 in the pathogenesis of the rheumatic diseases and its potential as a therapeutic target. Concept of an alarmin Mammalian organisms have evolved...

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Ngày tải lên: 10/08/2014, 16:22

Ngày tải lên: 10/08/2014, 16:23

Ngày tải lên: 10/08/2014, 16:23

Ngày tải lên: 10/08/2014, 16:23

Ngày tải lên: 10/08/2014, 16:23

Ngày tải lên: 12/08/2014, 18:21

... hatching until the end of experiment. Some of the chickens from each treatment group were infected with an isolate of ALV-J, ADOL-7501, at 2 weeks of age. The effects of viral infection were ... enhancement of mitogen response in chickens infected with Marek's disease virus and the herpesvirus of turkeys. Infect. Immun. 1978, 21 , 474-479. 26. Lillehoj, H. S. Effects of immunosuppression ... analyzed using two-tailed Student t-test with assumption of different variance. Significance of differences in percentage of viremia, antibody and the results of histopathology was determined by Chi-square...

Ngày tải lên: 07/08/2014, 17:22

... Ipadeola T. Clinical trial of riboflavin in sickle cell disease. East Afr Med J 1993; 70:418–21. 114 Clarke R. Homocysteine-lowering trials for pre- vention of heart disease and stroke. Semin ... levels of LH and FSH were higher in patients than in controls at the same stage of development of secondary sexual characteristics. This suggested a variation in the rate of maturation of the hypothalamic–pituitary ... stimula- tion tests and the conflicting results of hormonal assessment make it difficult to evaluate the role of endocrinal dysfunction in the pathogenesis of growth impairment. Endocrine function is...

Ngày tải lên: 12/02/2014, 19:20

... the inhibition of CYP activity observed in the absence of changes in protein expression in rabbit he- patocytes [22]. ROS indirectly reduced the activity of selected isoforms of CYP by inducing ... compilation ê 2011 FEBS Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction Tae-Hoon Kim*, Sang-Ho Lee* and Sun-Mee Lee School of Pharmacy, Sungkyunkwan University, ... studies suggest that some of the effects of HMGB1 result from its interaction with TLR2 or TLR4, leading to the media- tion of various cellular responses and the release of proinflammatory cytokines...

Ngày tải lên: 14/02/2014, 18:20

... Department of Neurodegenerative Disease, Institute of Neurology, London, UK Parkinson’s disease (PD) is a common neurodegenera- tive disease which affects over 1% of people over the age of 65 years ... that some of the genes involved in the genetics of Lewy body disease, have in common the fact that they impinge on ceramide metabolism. One shortfall of the present theory is the lack of neuro- pathological ... of the disorder, which often results in severe distal sensory loss and mutilating acropathy [32]. Although muta- tions in SPTLC1 cause neurological disease, there is, as yet, no description of...

Ngày tải lên: 18/02/2014, 14:20

Ngày tải lên: 19/02/2014, 22:20

... tuber-   - izations  . Another way of estimating the morbidity burden of disease is to calculate years of living with disability (YLD). The Global Burden of Disease Study estimates that COPD ... underdi-  extent of the underreporting varies across countries and depends on the level of awareness and understanding of COPD among health professionals, the organization of health care services ...  of disease burden that are consistent and measurable across nations. The authors of the Global Burden of Dis- ease Study designed a method to estimate the fraction of mortality...

Ngày tải lên: 21/02/2014, 12:20