pas with the alkyl tail located at the n terminus
Tài liệu Báo cáo khoa học: Different modes of dipeptidyl peptidase IV (CD26) inhibition by oligopeptides derived from the N-terminus of HIV-1 Tat indicate at least two inhibitor binding sites doc
Ngày tải lên :
20/02/2014, 11:20
... substrates The inhibition of the hydrolysis of the substrates in at least five different concentrations (10)5 M to · 10)5 M) in the absence and presence of different inhibitor concentrations around ... the application of simulated annealing techniques without applying a huge water box surrounding the whole enzyme– ligand complex and periodic boundary conditions Two independent simulated annealing ... different binding sites was reflected by the change of the slope in dependence of the inhibitor concentration At high inhibitor concentrations a hill coefficient of )1.6 was determined The Lineweaver–Burk...
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Báo cáo toán học: "A prolific construction of strongly regular graphs with the n-e.c. property" pptx
Ngày tải lên :
07/08/2014, 06:23
... and permutations are chosen uniformly at random Lemma 3.3 in Section shows that Construction generates many non-isomorphic graphs We then show that most of the graphs generated have the n- e.c property ... permutation πi The total number of ways of choosing the πi is (q!)q+1 , The functions σi,j in Construction supply another source of randomness in the designs Since there are q+1 functions to be chosen ... permutations adds more randomness to our construction than the choice of bijections Construction is the version of Construction that produces the graphs in Theorem 1.1 Construction Suppose that...
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Tài liệu Báo cáo khoa học: Basis of recognition between the NarJ chaperone and the N-terminus of the NarG subunit from Escherichia coli nitrate reductase pdf
Ngày tải lên :
16/02/2014, 14:20
... a conformational change in NarJ upon interaction with both NarG peptides B NarJ ⁄ NarG complex formation is mostly entropy driven and undergoes pH-dependent modulation of the binding affinity ... kinetic parameters of the interaction (on rate constant kon and off rate constant koff) between NarJ and the NarG(1–15) peptide Taking into account the existence of two subpopulations of NarJ at ... common feature of this new family of chaperones It is worth mentioning that the function of these proteins is not restricted to the recognition and binding of the N- terminus of the nascent metalloprotein,...
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Báo cáo khoa học: An arginyl in the N-terminus of the V1a vasopressin receptor is part of the conformational switch controlling activation by agonist docx
Ngày tải lên :
07/03/2014, 21:20
... recently that the N- terminus of the V1aR provides agonist-specific binding epitopes Consequently, truncation of the V1aR N- terminus prevented high affinity AVP binding but did not affect antagonist ... the conformational switch of the V1aR in the off-state The unique ability of arginyl to fulfil this constraining function in the N- terminus of the V1aR is similar to the unique constraining role ... high affinity agonist binding and signalling It is one of the constraining residues which maintain the V1aR in the inactive conformation and as such is part of the receptor activation switch There...
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Báo cáo Y học: The N-terminus of m5C-DNA methyltransferase Msp I is involved in its topoisomerase activity docx
Ngày tải lên :
24/03/2014, 00:21
... Characterisation of independent DNA and multiple Zn-binding domains at the N terminus of human DNA-(cytosine-5) methyltransferase: modulating the property of a DNA-binding domain by contiguous Zn-binding ... DNA was treated with M.MspI in topoisomerase I buffer Lane 1, DNA incubated with topoisomerase I (control); lane 2, DNA incubated with M.MspI; lane 3, DNA incubated with p26; lane 4, DNA incubated ... Methylation and imprinting: from host defense to gene regulation? Science 260, 309–310 Graessmann, M & Graessmann, A (1993) DNA Methylation, Chromatin Structure and the Regulation of Gene Expression...
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Báo cáo khoa học: Residues near the N-terminus of protein B control autocatalytic proteolysis and the activity of soluble methane mono-oxygenase doc
Ngày tải lên :
31/03/2014, 09:20
... full-length and truncated proteins (data not shown) These data, taken together with the SAXS study, are consistent with a relatively minor change in conformation on truncation of free protein B Similar ... Incremental truncation of protein B To investigate more thoroughly the role of the N- terminal region in the truncation reaction and in the activity of protein B, a series of N- terminal truncates ... indicated that a nucleophilic group was indeed present, because an increased reaction rate of p-nitrophenol formation was observed in the presence of increasing concentrations of protein B Control...
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The 11th form non-english majors’ level of satisfaction with their reading comprehension lessons at phan boi chau specialized upper secondary school, nghe an
Ngày tải lên :
07/11/2012, 14:54
... intended to be useful in either learning or using the L2 Strategies can be very different in nature, ranging from planning the -6- organization of one's learning (a metacognitive learning strategy) ... strategies “allow learners to control their own cognition - that is, to coordinate the learning process by using functions such as centering, arranging, planning, and evaluating”, affective strategies ... facilitate their learning new words • Analyzing expressions: students determine the meaning of a new expression by breaking it down into parts and using the meanings of the parts to understand the...
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Incorporating english cultural elements into english training with the comparing - contrasting approach: A case of tourism students at haiphong community college part 3
Ngày tải lên :
07/11/2012, 15:06
... Exploration- The student can evaluate a generalization about the target culture in terms of the amount of evidence substantiating it, and has the skills needed to locate and organize information ... Investigating conditions of Tourism students in learning English culture and their expectation on English culture - Finding out the effective ways of incorporating English cultural elements into the English ... ask the students to write a short composition, comparing and contrasting between men and women in the UK with the behaviour between men and women in their country 14 Task sheet Dating customs The...
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TEACHING READING ESP IN INTEGRATION WITH THE OTHER LANGUAGE SKILLS TO STUDENTS OF LINGUSTICS AT UNIVERSITY OF SOCIAL SCIENCES AND HUMANITIES, VIETNAM NATIONAL UNIVERSITY, HANOI
Ngày tải lên :
07/09/2013, 13:45
... aims at identifying and analyzing both strong points and weak points of the teaching and learning of reading ESP in Department of Linguistics and Vietnamese Studies at USSH – VNU based on the ... light of Communicative Language Teaching with a hope that there will be some improvement in teaching and learning reading skills in integration with the development of the other language skills ... introduces the advantages of skill-integration in teaching and learning reading and relationship between this skill and the other language skills Part C is the main part of the study It consists of two...
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THE 11TH FORM NON ENGLISH MAJORS’ LEVEL OF SATISFACTION WITH THEIR READING COMPREHENSION LESSONS AT PHAN BOI CHAU SPECIALIZED UP
Ngày tải lên :
07/09/2013, 13:48
... teachers and students involved in identifying and using information on learning on learning styles should proceed with caution and be aware that no single diagnostic instrument can solve all learning ... lesson plan In conclusion, bringing the gap between teachers’ and learners’ perception, narrowing the gap between teaching and learning play “an important role in enabling students to maximize their ... element in learning in general and in learning reading in particular but helping students to be satisfied with their reading lessons is a challenging task There are many factors that are worth considering...
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difficulties in teaching reading comprehension with the new english textbook “tieng anh 10” (the set of standard textbooks) to the 10th form students at ke sat high school
Ngày tải lên :
29/01/2014, 14:43
... : knowing Do not know what to when lack comprehension is - Do not see any organization Add on rather than integrate new + knowing what is information understood - Do not realize they not understand ... input This can help them to be acquainted with the theme and the language relating to the theme From then, the students can speak, listen and write about the things relating to the theme in the ... addition, understanding the teacher's explanation in English is the threat to the students They cannot understand all the things the teacher explains in English That is the reason why the teacher has...
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Tài liệu Báo cáo khoa học: Acetylcholinesterase from the invertebrate Ciona intestinalis is capable of assembling into asymmetric forms when co-expressed with vertebrate collagenic tail peptide doc
Ngày tải lên :
18/02/2014, 17:20
... and native enzyme expressed in vivo indicates the enzyme is AChE To determine the nature of the cholinesterase activity of the recombinant C intestinalis enzyme and to compare it with the native ... Sedimentation coefficients of recombinant and native forms of AChE from C intestinalis Data are the mean ± SE of ‡ determinations for recombinant enzyme and three and four determinations for enzyme ... with the AChE of Ciona savignyi GenScript Corporation (Piscataway, NJ, USA) synthesized and subcloned a cDNA for the protein into pcDNA3.1 (Invitrogen) after linker sequences containing EcoRI and...
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Báo cáo khoa học: Interactions of HIPPI, a molecular partner of Huntingtin interacting protein HIP1, with the specific motif present at the putative promoter sequence of the caspase-1, caspase-8 and caspase-10 genes pdf
Ngày tải lên :
07/03/2014, 10:20
... incorporated on the basis of this Detection of nuclear fragmentation, and caspase-1, caspase-3 and caspase-8 activation Nuclear fragmentation, and caspase-1, caspase-3 and caspase-8 activation, were ... showing gradual increase in fluorescence intensity of GST–HIPPI (0.8 lM) at 340 nm (kexc ¼ 295 nm) at saturation level of binding with the bp motif AAAGACATG with increasing salt (NaCl) concentrations ... comparison with that obtained with the wild-type 60 bp sequence The result of this experiment is shown in Fig 3, and indicates that mutation of the specific site of the binding motif at the putative...
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Báo cáo khoa học: Nitric oxide formation from the reaction of nitrite with carp and rabbit hemoglobin at intermediate oxygen saturations pdf
Ngày tải lên :
16/03/2014, 06:20
... The maximal HbNO concentration during the reaction of nitrite with hemoglobin depends on initial oxygen saturation and on oxygen afnity The maximal HbNO concentration is plotted as a function ... ATP on the reaction of nitrite with carp hemoglobin at different oxygen saturations Concentration proles of oxygenated hemoglobin, methemoglobin, nitrosylhemoglobin and deoxygenated hemoglobin are ... Nitritehemoglobin reactions at different O2 saturations F B Jensen documenting that nitrite causes vasodilation and increases blood ow, consistent with its conversion into NO by hemoglobin and...
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Báo cáo Y học: Differential scanning calorimetric study of myosin subfragment 1 with tryptic cleavage at the N-terminal region of the heavy chain pdf
Ngày tải lên :
17/03/2014, 10:20
... performed under the same conditions, at the same protein concentration (1 mgÆmL)1), and even in the same rotor Both these S1 species demonstrated sharp sedimentation boundaries, and sedimentation coefficients ... F-actin and retained in the supernatant We observed no boundaries of the protein sedimenting with the coefficient of about S in these experiments These results indicated that Nt-S1, like S1 and t-S1, ... treatment such as subtraction of instrumental background, concentration normalization, and chemical baseline correction, they can be used for the description of the irreversible thermal denaturation...
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Human resources for industrialization and modernization associated with the development of knowledge based economy in the province of thua thien hue at the present time
Ngày tải lên :
22/07/2014, 18:29
... country in the context of globalization and international economic integration Globalization and economic 39 integration in the world is an objective trend, creating opportunities for developing ... resolved in Danang, offering points of orientations and proposed solutions to the human resources development for industrialization and modernization in Da Nang in the near future, namely: socioeconomic ... modernization associated with the development of the knowledge-based economy Evaluation of natural conditions, socio- economic situations influencing the formation and development of human resources...
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Báo cáo lâm nghiệp: "Spatio-temporal pattern of bog pine (Pinus uncinata var. rotundata) at the interface with the Norway spruce (Picea abies) belt on the edge of a raised bog in the Jura Mountains, Switzerland" doc
Ngày tải lên :
08/08/2014, 01:21
... that there has been a drastic increase in pine pollen abundance in the recent past within peat profiles, although pine (Pinus spp.) stands are rather scattered throughout the Jura region In some ... survived in such wet conditions unless the environmental conditions changed, i.e the bog dried and the water table sank 4.5 Primeval niche of bog pine and projection of pine stands into the future ... relation with climatic change and increasing temperatures [22], it is not excluded that increasing summer temperatures will enhance pine evapotranspiration and accelerate further new centripetal dynamics...
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Báo cáo y học: "Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus" pps
Ngày tải lên :
09/08/2014, 10:20
... haplotypes in the NAT2 gene in the Japanese population, namely NAT2*4, NAT2*5B, NAT2*5E, NAT2*6A, NAT2*7B and NAT2*13 Of these, NAT2*4 is the wild-type haplotype; the remaining haplotypes are mutant types ... DNA from the blood samples Genotyping at the single nucleotide polymorphisms in the NAT2 gene and inference of haplotype combinations The NAT2 gene has at least 13 SNPs Genotyping at four SNP ... major components of the NAT2 mutant haplotype in Caucasian individuals are NAT2*5B and NAT2*6A; in the Japanese population, NAT2*6A and NAT2*7B are the major components Each haplotype contains specific...
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báo cáo khoa học: "D -Cn S1 α another allele associated with a decreased synthesis rate at the caprine α locus -casein S1" ppsx
Ngày tải lên :
09/08/2014, 22:22
... transmitted to their daughters, an observation at variance with the conclusions of the present note Re-examination of the surviving dam-daughter pairs among the considered by these authors suggests the ... occurrence of parentage errors in this sample The non-transmission of fraction D in the remaining pairs is attributable to mere chance (P= 0.03) Allele a is the seventh allele identified at the goat ... ,-Cn s were 0.05 in Alpine and 0.03 in Saanen Because in their data a was not distinD -Cn S1 guished from a these values in fact apply to the combined frequencies of , O ,-Cn s o -Cn S1 a and...
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