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Báo cáo khoa học: Identification of tyrosine-phosphorylation sites in the nuclear membrane protein emerin pot
Ngày tải lên :
07/03/2014, 12:20
... emerin Emerin is the product of a gene linked to EDMD [19,21] An integral membrane protein specifically located at the inner nuclear membrane, emerin, like other INM proteins, binds to lamins ... mislocalization of emerin that is caused by the loss of emerin binding to lamin A (X- linked form) or by the loss of lamin A (autosomal dominant form) [22,23] Several emerin binding partners have ... Scheme for the identification of emerin phosphorylation sites HeLa cells were grown in two different populations, one in normal medium and the other in medium containing arginine and lysine labeled...
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Báo cáo khoa học: Evaluation of potential regulatory elements identi®ed as DNase I hypersensitive sites in the CFTR gene doc
Ngày tải lên :
08/03/2014, 10:20
... increasing amounts of DNase show a proportionate increase in the intensity of the DHS fragments in the control samples In Fig 7A the forskolin-treated chromatin shows a relative increase in the ... similar intensity but the DHS in intron 18 is less evident (Fig 5B) In contrast, the DHS in intron 18 is more prominent than those in introns 16 and 17 (Fig 5A) in chromatin from Capan1 cells The ... the pancreatic cell lines Capan1 and NP31 were evaluated further DHS in airway epithelial cells were investigated further in the airway carcinoma cell line Calu3 Of particular interest were the...
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Báo cáo khoa học: Two CCAAT/enhancer binding protein sites in the cytochrome P4503A1 locus Potencial role in the glucocorticoid response ppt
Ngày tải lên :
17/03/2014, 09:20
... Characterization of the C/EBP binding sequences in the CYP3A1 promoter region We used gel mobility-shift assays, with the goal of identifying active C/EBPa binding sites within the CYP3A1 locus ... performed using an anti-C/EBPa Ig Symbol ÔsÕ in panel B and C denotes the position of the C/EBP containing complex and the arrowhead ÔssÕ the position of the DNAÆprotein complex shifted by the specific ... poly(vinylidene difluoride) membranes, and the membranes incubated with a specific anti-C/EBPa Ig Protein loading control using Amido Black staining of the membrane is shown in the bottom panel...
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Possible Strategies for Listening Comprehension: Applying the Concepts of Conversational Implicature and Adjacency Pairs to Understand Speaker Intention in the TOEFL Listening Section doc
Ngày tải lên :
24/03/2014, 19:20
... whether or not the understanding of speaker intention will contribute to choosing the correct answers in the TOEFL Listening Section The results indicate that the feasibility of the training ... enjoyable tasks) ▪Maintaining and protecting motivation (making learning and tasks stimulating; setting learner specific goals; increasing their self-confidence; allowing learners to maintain a positive ... presented the opinions of each group to the class I asked them to discuss such issues as whether the series of listening strategies applying conversational analysis was interesting to them, whether the...
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Báo cáo khoa học: Autoregulatory binding sites in the zebrafish six3a promoter region define a new recognition sequence for Six3 proteins potx
Ngày tải lên :
29/03/2014, 08:20
... that intramolecular interactions involving residues outside of the protein–DNA binding interface can also in uence DNA recognition [10,40] In particular, variations in the position of the N-terminal ... comparisons of the binding affinities of the 18 different ATTA-containing sites In this study, we used a biotin-labelled 27 bp DNA fragment containing a1 as a probe in EMSAs, and tested the in uence ... binding mode of the HD and in uence the nucleotide contacts made by the recognition helix [6] Notably, these different binding modes seemed to depend on the binding site sequence, and the binding...
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Báo cáo khoa học: Co-operation of domain-binding and calcium-binding sites in the activation of gelsolin pptx
Ngày tải lên :
31/03/2014, 01:20
... actin-binding sites, is in interaction with the C-terminal a-helix of G6 domain The sequence 159–193, including the second actin interface, appears also in interaction with G6 domain Therefore, ... domain Footprint of G2 on gelsolin G4–6 domain Two sites within the G2 domain appear involved in the G2- G4–6 interface in the presence of EGTA (Fig 3) The interaction of these two sites (residues ... 0.5–0.8 lM) in EGTA, weaker binding was evident in the presence of mM calcium (Fig 5) In addition a change in the interface occurs during calcium binding to IIG6 site (Fig 6) The interaction...
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Báo cáo khoa học: "Histochemical Characterization of the Lectin-binding Sites in the Equine Vomeronasal Organ" potx
Ngày tải lên :
07/08/2014, 17:22
... of the Lectin-binding Sites in the Equine Vomeronasal Organ 17 Fig Histochemical staining of DBA (A and B), SBA (C and D), and Isolectin B4 (E and F) in the vomeronasal sensory epithelium of the ... consisted of the receptor, supporting cells, and basal cells The J acobson's glands were situated in the lamina propria Since the ducts of these glands penetrated the epithelium and opened into the VNO ... immunohistochemistry[7,12], the observed lectin-binding patterns of the equine receptor cells may reflect the various subtypes of the vomeronasal receptor cells in the horse The marmoset supporting cells showed positive...
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Báo cáo khoa học: "An artificial regeneration system for establishing northern red oak on dry-mesic sites in the Lake States, USA" pptx
Ngày tải lên :
08/08/2014, 23:22
... micro-environments Moreover, we expect the "best growth" to occur in the unsprayed 25% crown cover plots in future years Thus far the seedlings in these plots are the tallest seedlings in the study, and even greater ... considering the recent restrictions on the use of herbicides in the US It also reinforces the importance of selecting sites where understory competition is minimal while at the same time providing adequate ... of competing vegetation and to seedling dieback caused by a late spring frost in 1992 Herbicide spraying temporarily reduced the density of competing vegetation in the clearcut during the first...
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Báo cáo khoa hoc:" Despite WT1 binding sites in the promoter region of human and mouse nucleoporin glycoprotein 210, WT1 does not influence expression of GP210" pptx
Ngày tải lên :
11/08/2014, 08:20
... amino acid insert and the KTS insert in the zinc finger region, did not influence GP210 expression in SAOS osterosarcoma cells, in a system using tetracycline-induced repression of expression In ... determine whether the putative WT1 binding sites in the GP210 promoter might correspond to functional reg- The present study describes the genomic structure of the human nucleoporin GP210 gene, including ... for either of these proteins The 121-kDa pore membrane protein POM121 [7,8] is located in the pore membrane domain of the NPC with a short (29 residues) N-terminal tail protruding into the lumen...
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Báo cáo y học: "Multiple sites in the N-terminal half of simian immunodeficiency virus capsid protein contribute to evasion from rhesus monkey TRIM5a-mediated restriction" docx
Ngày tải lên :
13/08/2014, 01:20
... (Figures and 3A), clearly excluding the possibility that some of the determinants lie outside the CA We then generated a chimeric GH123 containing the N-terminal half (from the 1st to 120th) of SIVmac239 ... with SIVmac239/P) in the viral ability to saturate TRIM5a in Rh FRhK4 cells, and suggest that the multiple sites in the N-terminal half of GH123 CA affect its binding to Rh TRIM5a Finally, we checked ... GH123/Q In the case of Rh TRIM5a, it has been reported that Rh TRIM5a sensitivity determinants lie in the loop between a-helices and of CA protein, equivalent to the cyclophilin A (CypA) binding...
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Báo cáo y học: " Processing sites in the human immunodeficiency virus type 1 (HIV-1) Gag-Pro-Pol precursor are cleaved by the viral protease at different rates" ppt
Ngày tải lên :
13/08/2014, 09:21
... pausing during expression The activity of the intrinsic protease was inactivated by a D25A substitution of the catalytic aspartate The location of the Gag NC/p1 [53] and pl/p6 [54] sites and the ... processing products The first we assigned the products based on the known processing sites in Gag-Pro-Pol The size of the pi120 intermediate was consistent with an initial cleavage at the p2/NC ... (presumably at the same rate this site is cleaved in Gag), generating the pi120 NC-TFPR-RT-RH -IN intermediate and the p42 MA-CA-p2 intermediate The next cleavage removes IN from the C terminus of pi120...
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Báo cáo y học: "Motif composition, conservation and condition-specificity of single and alternative transcription start sites in the Drosophila genome" docx
Ngày tải lên :
14/08/2014, 21:20
... support for the identified sites across the Drosophila genome, for a single gene the TSS location information is often incomplete using either database, and inconsistent using both The TSSs identified ... TSSs in the EPD and our sets, highlighting the bias in the usage of the most 5' evidence as TSSs, rather than the most highly utilized locations Looking at the presence of sequence motifs within ... begin with a start codon, indicating that no transcript evidence is available and making the annotation incomplete on the 5' end Filtering out such simple cases does not mean that the remaining...
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Techniques for teaching production in the lesson listen and read english 9
Ngày tải lên :
14/08/2017, 08:28
... the entrance to the village e.They visited the shrine on the mountain f In the afternoon, they went boating in the river and had a picnic on the river bank before going home late in the evening ... visit the shrine a In the afternoon, they went boating in the river and had a picnic on the river bank f They went home late in the evening Unit 4: LEARNING A FOREIGN LANGUAGE Period 20: GETTING ... working in pairs Comparision Compare the contents of the lesson with the facts Expressing feelings and opinions Express feelings and opinions about the content or characters in the dialogue Imagination...
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Unit 1: A day in the life of. Listening
Ngày tải lên :
21/06/2013, 01:26
... WHILE-LISTENING Pre order these pictures WHILE-LISTENING Listen and order these pictures WHILE-LISTENING Listen again and decide whether the statements are True (T) or False (F) Mr Lam lives in ... routine:/ru:'ti:n/ pedal:/'pedl/ office:/'ɔfis/ food stall:/fu:d stɔ:l/ purchase:/'pə:t∫əs/ drop:/drɔp/ passengers:/'pæsindʒə/ ride:/raid/ WHILE-LISTENING Look at the pictures and describe them ... PRE-LISTENING WHO IS HE? - He gets up very early - He has got a cyclo - He usually has meals at a foot stall - He drives passengers to everywhere they want HE IS A CYCLO DRIVER PRE-LISTENING Listen...
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Real Audio to Augment Real Listening in the ESL Classroom
Ngày tải lên :
06/09/2013, 10:10
... enjoy include: • • • • • • Listening to information that interests them Listening to sound clips over and over again Listening to a variety of voices which strengthens listening ability Being encouraged ... students would enjoy doing research about a particular topic and then sharing their findings with the rest of the class For example, Give the students the topic of Martin Luther King Jr and some questions ... the meaning through context Ticking off Items For those interested in practicing with listening for specific information, have the students tick off items from a list While the students are listening...
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DIFFICULTIES IN TEACHING LISTENING COMPREHENSION IN THE COURSE BOOK
Ngày tải lên :
07/09/2013, 13:37
... students’ opinion on the Listening Comprehension of the course book “Head for Business”, on the exercises in the LC and requirements for learning listening, on extra practice listening, and on the Listening ... employ the traditional method of teaching listening Classes are usually conducted in the form of lectures, with most of the time the 11 teachers playing the key role in the classroom, being the main ... supplementary listening A Yes Table 3: Students’ opinions on the exercises in the LC and requirements for learning/teaching listening Regarding students’ opinion on the exercises in the LC and requirements...
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A study of difficulties in learning english listening skill for beginners in the asemlink of intrernational languages center and some suggested solutions
Ngày tải lên :
14/12/2013, 00:41
... interesting topics for further listening The authentic listening material is usually interesting because the listeners are exposed to the real life With the listening text in the text book, the ... Dinh Phuong (2006), there are two ways of listening in the real life They are casual listening and focused listening depending on the purpose of listening One type of listening, casual listening, ... results of the process of studying the theoretical background, then working out the real difficulties in learning the English listening skill in the Asemlink center based on the theory Finally,...
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Tài liệu Limit the Data Displayed in a Bound List Box doc
Ngày tải lên :
21/01/2014, 12:20
... created called btnLoadList Enter the code in Listing 1.2 in the Click event of the btnLoadList button This code loads the data entered from txtCustLimit into the parameter of the OleDBDataAdapter1, ... supplied, as indicated by the ? This will be performed using code in the final step of this How-To The % is a wildcard that tells the server to make it a fuzzy search Resize the ListBox control, ... created by using the ? in the Select statement of the data adapter Then Dataset1 is cleared of its data with the Clear method Finally, DataSet1 is refilled with data based off the value in txtCustLimit,...
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Tài liệu Báo cáo khoa học: Effect of deletion of the DNase I hypersensitive sites on the transcription of chicken Ig-b gene and on the maintenance of active chromatin state in the Ig-b locus docx
Ngày tải lên :
19/02/2014, 16:20
... histones, and the remaining DHSs in the deleted cells were examined to determine the roles of these DHSs on the transcription of Ig-b gene and on the maintenance of the active chromatin state Results ... sensitivity in the b-globin locus are the same as the wild type control [17] Thus, there again has been no description either of the region involved in DNase I general sensitivity or of the region for the ... without DHSs deleted in this study because the positions of DHSs remain the same In the chicken b-globin locus, the DNase I sensitive region coincides with the region in which the core histones...
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